RHEA:10020          (APPROVED)

H2O + L-saccharopine + NADP(+) = (S)-2-amino-6-oxohexanoate + H(+) + L-glutamate + NADPH

Last modified: 2020-02-03. Chemically balanced: yes.

H2O
CHEBI:15377
chebi link
Formula: H2O
Charge: 0
(no structure available)
+
L-saccharopine
CHEBI:57951
chebi link
Formula: C11H19N2O6
Charge: -1
(no structure available)
+
NADP+
CHEBI:58349
chebi link
Formula: C21H25N7O17P3
Charge: -3
(no structure available)
=
(S)-2-amino-6-oxohexanoate
CHEBI:58321
chebi link
Formula: C6H11NO3
Charge: 0
(no structure available)
+
H+
CHEBI:15378
chebi link
Formula: H
Charge: 1
(no structure available)
+
L-glutamate
CHEBI:29985
chebi link
Formula: C5H8NO4
Charge: -1
(no structure available)
+
NADPH
CHEBI:57783
chebi link
Formula: C21H26N7O17P3
Charge: -4
(no structure available)

Same participants, different directions

RHEA:10021 H2O + L-saccharopine + NADP(+) => (S)-2-amino-6-oxohexanoate + H(+) + L-glutamate + NADPH
RHEA:10022 (S)-2-amino-6-oxohexanoate + H(+) + L-glutamate + NADPH => H2O + L-saccharopine + NADP(+)
RHEA:10023 H2O + L-saccharopine + NADP(+) <=> (S)-2-amino-6-oxohexanoate + H(+) + L-glutamate + NADPH

Links to other resources

Enzymes
Enzyme classification
EC 1.5.1.10  [ENZYME]  [IntEnz]
UniProtKB
 [reviewed protein(s)]  [all proteins(s)]
Reactions
KEGG reaction
R02315
MetaCyc
RXN3O-127

Reaction relationships

Outgoing
no data
Incoming
no data

Citations

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