RHEA:10176          (APPROVED)

(2S,3R)-2-hydroxy-3-(indol-3-yl)butanoate + NAD(+) = (R)-3-(indol-3-yl)-2-oxobutanoate + H(+) + NADH

Last modified: 2019-11-04. Chemically balanced: yes.

(2S,3R)-2-hydroxy-3-(indol-3-yl)butanoate
CHEBI:131783
chebi link
Formula: C12H12NO3
Charge: -1
(no structure available)
+
NAD+
CHEBI:57540
chebi link
Formula: C21H26N7O14P2
Charge: -1
(no structure available)
=
(R)-3-(indol-3-yl)-2-oxobutanoate
CHEBI:91180
chebi link
Formula: C12H10NO3
Charge: -1
(no structure available)
+
H+
CHEBI:15378
chebi link
Formula: H
Charge: 1
(no structure available)
+
NADH
CHEBI:57945
chebi link
Formula: C21H27N7O14P2
Charge: -2
(no structure available)

Same participants, different directions

RHEA:10177 (2S,3R)-2-hydroxy-3-(indol-3-yl)butanoate + NAD(+) => (R)-3-(indol-3-yl)-2-oxobutanoate + H(+) + NADH
RHEA:10178 (R)-3-(indol-3-yl)-2-oxobutanoate + H(+) + NADH => (2S,3R)-2-hydroxy-3-(indol-3-yl)butanoate + NAD(+)
RHEA:10179 (2S,3R)-2-hydroxy-3-(indol-3-yl)butanoate + NAD(+) <=> (R)-3-(indol-3-yl)-2-oxobutanoate + H(+) + NADH

Links to other resources

Enzymes
Enzyme classification
EC 1.1.1.397  [ENZYME]  [IntEnz]
UniProtKB
 [reviewed protein(s)]  [all proteins(s)]
Reactions
KEGG reaction
R11336
MetaCyc
RXN-17529

Reaction relationships

Outgoing
RHEA:10176
is a
RHEA:34555
a (2S)-2-hydroxycarboxylate + NAD(+) = a 2-oxocarboxylate + H(+) + NADH
Incoming
no data

Citations

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