RHEA:10180          (APPROVED)

(6S)-10-formyltetrahydrofolate + H2O + NADP(+) = (6S)-5,6,7,8-tetrahydrofolate + CO2 + H(+) + NADPH

Last modified: 2020-04-08. Chemically balanced: yes.

(6S)-10-formyltetrahydrofolate
CHEBI:57454
chebi link
Formula: C20H21N7O7
Charge: -2
(no structure available)
+
H2O
CHEBI:15377
chebi link
Formula: H2O
Charge: 0
(no structure available)
+
NADP+
CHEBI:58349
chebi link
Formula: C21H25N7O17P3
Charge: -3
(no structure available)
=
(6S)-5,6,7,8-tetrahydrofolate
CHEBI:57453
chebi link
Formula: C19H21N7O6
Charge: -2
(no structure available)
+
CO2
CHEBI:16526
chebi link
Formula: CO2
Charge: 0
(no structure available)
+
H+
CHEBI:15378
chebi link
Formula: H
Charge: 1
(no structure available)
+
NADPH
CHEBI:57783
chebi link
Formula: C21H26N7O17P3
Charge: -4
(no structure available)

Same participants, different directions

RHEA:10181 (6S)-10-formyltetrahydrofolate + H2O + NADP(+) => (6S)-5,6,7,8-tetrahydrofolate + CO2 + H(+) + NADPH
RHEA:10182 (6S)-5,6,7,8-tetrahydrofolate + CO2 + H(+) + NADPH => (6S)-10-formyltetrahydrofolate + H2O + NADP(+)
RHEA:10183 (6S)-10-formyltetrahydrofolate + H2O + NADP(+) <=> (6S)-5,6,7,8-tetrahydrofolate + CO2 + H(+) + NADPH

Links to other resources

Enzymes
Enzyme classification
EC 1.5.1.6  [ENZYME]  [IntEnz]
UniProtKB
 [reviewed protein(s)]  [all proteins(s)]
Reactions
KEGG reaction
R00941
MetaCyc
FORMYLTETRAHYDROFOLATE-DEHYDROGENASE-RXN

Reaction relationships

Outgoing
no data
Incoming
no data

Citations

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