RHEA:10247          (APPROVED)

4-fumarylacetoacetate + H2O <=> acetoacetate + fumarate + H(+)

Last modified: 2019-05-24. Chemically balanced: yes.

4-fumarylacetoacetate
CHEBI:18034
chebi link
Formula: C8H6O6
Charge: -2
(no structure available)
+
H2O
CHEBI:15377
chebi link
Formula: H2O
Charge: 0
(no structure available)
<=>
acetoacetate
CHEBI:13705
chebi link
Formula: C4H5O3
Charge: -1
(no structure available)
+
fumarate
CHEBI:29806
chebi link
Formula: C4H2O4
Charge: -2
(no structure available)
+
H+
CHEBI:15378
chebi link
Formula: H
Charge: 1
(no structure available)

Same participants, different directions

RHEA:10244 4-fumarylacetoacetate + H2O = acetoacetate + fumarate + H(+)
RHEA:10245 4-fumarylacetoacetate + H2O => acetoacetate + fumarate + H(+)
RHEA:10246 acetoacetate + fumarate + H(+) => 4-fumarylacetoacetate + H2O

Links to other resources

Enzymes
Enzyme classification
EC 3.7.1.2  [ENZYME]  [IntEnz]
UniProtKB
 [reviewed protein(s)]  [all proteins(s)]
Reactions
KEGG reaction
R01364
MetaCyc
FUMARYLACETOACETASE-RXN
MACiE
M0180
Reactome
R-HSA-71181.4

Reaction relationships

Outgoing
no data
Incoming
no data

Citations

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