RHEA:10489          (APPROVED)

5-formyltetrahydrofolate + ATP => 5,10-methenyltetrahydrofolate + ADP + phosphate

Last modified: 2015-06-22. Chemically balanced: yes.

5-formyltetrahydrofolate
CHEBI:57457
chebi link
Formula: C20H21N7O7
Charge: -2
(no structure available)
+
ATP
CHEBI:30616
chebi link
Formula: C10H12N5O13P3
Charge: -4
(no structure available)
=>
5,10-methenyltetrahydrofolate
CHEBI:57455
chebi link
Formula: C20H20N7O6
Charge: -1
(no structure available)
+
ADP
CHEBI:456216
chebi link
Formula: C10H12N5O10P2
Charge: -3
(no structure available)
+
phosphate
CHEBI:43474
chebi link
Formula: HO4P
Charge: -2
(no structure available)

Same participants, different directions

RHEA:10488 5-formyltetrahydrofolate + ATP = 5,10-methenyltetrahydrofolate + ADP + phosphate
RHEA:10490 5,10-methenyltetrahydrofolate + ADP + phosphate => 5-formyltetrahydrofolate + ATP
RHEA:10491 5-formyltetrahydrofolate + ATP <=> 5,10-methenyltetrahydrofolate + ADP + phosphate

Links to other resources

Enzymes
Enzyme classification
EC 6.3.3.2  [ENZYME]  [IntEnz]
UniProtKB
 [reviewed protein(s)]  [all proteins(s)]
Reactions
KEGG reaction
R02301
EcoCyc
5-FORMYL-THF-CYCLO-LIGASE-RXN
MetaCyc
5-FORMYL-THF-CYCLO-LIGASE-RXN

Reaction relationships

Outgoing
no data
Incoming
no data

Citations

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