RHEA:10721          (APPROVED)

2-amino-6-acetyl-3,7,8,9-tetrahydro-3H-pyrimido[4,5-b][1,4]diazepin-4-one + glutathione disulfide + H2O => 6-pyruvoyl-5,6,7,8-tetrahydropterin + 2 glutathione

Last modified: 2017-03-16. Chemically balanced: yes.

2-amino-6-acetyl-3,7,8,9-tetrahydro-3H-pyrimido[4,5-b][1,4]diazepin-4-one
CHEBI:27714
chebi link
Formula: C9H11N5O2
Charge: 0
(no structure available)
+
glutathione disulfide
CHEBI:58297
chebi link
Formula: C20H30N6O12S2
Charge: -2
(no structure available)
+
H2O
CHEBI:15377
chebi link
Formula: H2O
Charge: 0
(no structure available)
=>
6-pyruvoyl-5,6,7,8-tetrahydropterin
CHEBI:136564
chebi link
Formula: C9H11N5O3
Charge: 0
(no structure available)
+
2
glutathione
CHEBI:57925
chebi link
Formula: C10H16N3O6S
Charge: -1
(no structure available)

Same participants, different directions

RHEA:10720 2-amino-6-acetyl-3,7,8,9-tetrahydro-3H-pyrimido[4,5-b][1,4]diazepin-4-one + glutathione disulfide + H2O = 6-pyruvoyl-5,6,7,8-tetrahydropterin + 2 glutathione
RHEA:10722 6-pyruvoyl-5,6,7,8-tetrahydropterin + 2 glutathione => 2-amino-6-acetyl-3,7,8,9-tetrahydro-3H-pyrimido[4,5-b][1,4]diazepin-4-one + glutathione disulfide + H2O
RHEA:10723 2-amino-6-acetyl-3,7,8,9-tetrahydro-3H-pyrimido[4,5-b][1,4]diazepin-4-one + glutathione disulfide + H2O <=> 6-pyruvoyl-5,6,7,8-tetrahydropterin + 2 glutathione

Links to other resources

Enzymes
Enzyme classification
EC 1.5.4.1  [ENZYME]  [IntEnz]
UniProtKB
 [reviewed protein(s)]  [all proteins(s)]
Reactions
KEGG reaction
R03984
MetaCyc
1.5.4.1-RXN

Reaction relationships

Outgoing
no data
Incoming
no data

Citations

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