RHEA:11281          (APPROVED)

(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + dCMP + H2O => (6S)-5,6,7,8-tetrahydrofolate + 5-hydroxymethyl-dCMP

Last modified: 2019-11-22. Chemically balanced: yes.

(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate
CHEBI:15636
chebi link
Formula: C20H21N7O6
Charge: -2
(no structure available)
+
dCMP
CHEBI:57566
chebi link
Formula: C9H12N3O7P
Charge: -2
(no structure available)
+
H2O
CHEBI:15377
chebi link
Formula: H2O
Charge: 0
(no structure available)
=>
(6S)-5,6,7,8-tetrahydrofolate
CHEBI:57453
chebi link
Formula: C19H21N7O6
Charge: -2
(no structure available)
+
5-hydroxymethyl-dCMP
CHEBI:57962
chebi link
Formula: C10H14N3O8P
Charge: -2
(no structure available)

Same participants, different directions

RHEA:11280 (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + dCMP + H2O = (6S)-5,6,7,8-tetrahydrofolate + 5-hydroxymethyl-dCMP
RHEA:11282 (6S)-5,6,7,8-tetrahydrofolate + 5-hydroxymethyl-dCMP => (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + dCMP + H2O
RHEA:11283 (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + dCMP + H2O <=> (6S)-5,6,7,8-tetrahydrofolate + 5-hydroxymethyl-dCMP

Links to other resources

Enzymes
Enzyme classification
EC 2.1.2.8  [ENZYME]  [IntEnz]
UniProtKB
 [reviewed protein(s)]  [all proteins(s)]
Reactions
KEGG reaction
R01669
MetaCyc
2.1.2.8-RXN

Reaction relationships

Outgoing
no data
Incoming
no data

Citations

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