RHEA:11612          (APPROVED)

H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+)

Last modified: 2020-02-03. Chemically balanced: yes.

H2O
CHEBI:15377
chebi link
Formula: H2O
Charge: 0
(no structure available)
+
L-glutamate
CHEBI:29985
chebi link
Formula: C5H8NO4
Charge: -1
(no structure available)
+
NADP+
CHEBI:58349
chebi link
Formula: C21H25N7O17P3
Charge: -3
(no structure available)
=
2-oxoglutarate
CHEBI:16810
chebi link
Formula: C5H4O5
Charge: -2
(no structure available)
+
H+
CHEBI:15378
chebi link
Formula: H
Charge: 1
(no structure available)
+
NADPH
CHEBI:57783
chebi link
Formula: C21H26N7O17P3
Charge: -4
(no structure available)
+
NH4+
CHEBI:28938
chebi link
Formula: H4N
Charge: 1
(no structure available)

Same participants, different directions

RHEA:11613 H2O + L-glutamate + NADP(+) => 2-oxoglutarate + H(+) + NADPH + NH4(+)
RHEA:11614 2-oxoglutarate + H(+) + NADPH + NH4(+) => H2O + L-glutamate + NADP(+)
RHEA:11615 H2O + L-glutamate + NADP(+) <=> 2-oxoglutarate + H(+) + NADPH + NH4(+)

Comments

RHEA:11609 part of RHEA:15501

Links to other resources

Enzymes
Enzyme classification
EC 1.4.1.3  [ENZYME]  [IntEnz]
Enzyme classification
EC 1.4.1.4  [ENZYME]  [IntEnz]
UniProtKB
 [reviewed protein(s)]  [all proteins(s)]
Reactions
KEGG reaction
R00248
EcoCyc
GLUTDEHYD-RXN
MetaCyc
GLUTAMATESYN-RXN
MetaCyc
GLUTAMATE-DEHYDROGENASE-NADP%2b-RXN
MetaCyc
GLUTDEHYD-RXN
Reactome
R-HSA-70600.4
Reactome
R-HSA-70589.4

Reaction relationships

Outgoing
no data
Incoming
no data

Citations

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