RHEA:11682          (APPROVED)

AMP + diphosphate + GMP + 2 H(+) + L-glutamate => ATP + H2O + L-glutamine + XMP

Last modified: 2018-01-25. Chemically balanced: yes.

ATP
CHEBI:30616
chebi link
Formula: C10H12N5O13P3
Charge: -4
(no structure available)
+
H2O
CHEBI:15377
chebi link
Formula: H2O
Charge: 0
(no structure available)
+
L-glutamine
CHEBI:58359
chebi link
Formula: C5H10N2O3
Charge: 0
(no structure available)
+
XMP
CHEBI:57464
chebi link
Formula: C10H11N4O9P
Charge: -2
(no structure available)
<=
AMP
CHEBI:456215
chebi link
Formula: C10H12N5O7P
Charge: -2
(no structure available)
+
diphosphate
CHEBI:33019
chebi link
Formula: HO7P2
Charge: -3
(no structure available)
+
GMP
CHEBI:58115
chebi link
Formula: C10H12N5O8P
Charge: -2
(no structure available)
+
2
H+
CHEBI:15378
chebi link
Formula: H
Charge: 1
(no structure available)
+
L-glutamate
CHEBI:29985
chebi link
Formula: C5H8NO4
Charge: -1
(no structure available)

Same participants, different directions

RHEA:11680 ATP + H2O + L-glutamine + XMP = AMP + diphosphate + GMP + 2 H(+) + L-glutamate
RHEA:11681 ATP + H2O + L-glutamine + XMP => AMP + diphosphate + GMP + 2 H(+) + L-glutamate
RHEA:11683 ATP + H2O + L-glutamine + XMP <=> AMP + diphosphate + GMP + 2 H(+) + L-glutamate

Comments

Multi-step reaction: RHEA:15889 and RHEA:18301

Links to other resources

Enzymes
Enzyme classification
EC 6.3.5.2  [ENZYME]  [IntEnz]
UniProtKB
 [reviewed protein(s)]  [all proteins(s)]
Reactions
KEGG reaction
R01231
EcoCyc
GMP-SYN-GLUT-RXN
MetaCyc
GMP-SYN-GLUT-RXN
MACiE
M0234
Reactome
R-HSA-73792.2

Reaction relationships

Outgoing
no data
Incoming
no data

Citations

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