RHEA:11689          (APPROVED)

ATP + L-leucine + tRNA(Leu) => AMP + diphosphate + L-leucyl-tRNA(Leu)

Last modified: 2018-01-25. Chemically balanced: yes.

ATP
CHEBI:30616
chebi link
Formula: C10H12N5O13P3
Charge: -4
(no structure available)
+
L-leucine
CHEBI:57427
chebi link
Formula: C6H13NO2
Charge: 0
(no structure available)
+
tRNALeu
GENERIC:9613
(RHEA-COMP:9613)
(no structure available)
AMP 3'-end residue
CHEBI:78442
chebi link
Formula: C10H12N5O6P
Charge: -1
Position: 
=>
AMP
CHEBI:456215
chebi link
Formula: C10H12N5O7P
Charge: -2
(no structure available)
+
diphosphate
CHEBI:33019
chebi link
Formula: HO7P2
Charge: -3
(no structure available)
+
L-leucyl-tRNALeu
GENERIC:9622
(RHEA-COMP:9622)
(no structure available)
3'-(L-leucyl)adenylyl group
CHEBI:78494
chebi link
Formula: C16H24N6O7P
Charge: 0
Position: 

Same participants, different directions

RHEA:11688 ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu)
RHEA:11690 AMP + diphosphate + L-leucyl-tRNA(Leu) => ATP + L-leucine + tRNA(Leu)
RHEA:11691 ATP + L-leucine + tRNA(Leu) <=> AMP + diphosphate + L-leucyl-tRNA(Leu)

Links to other resources

Enzymes
Enzyme classification
EC 6.1.1.4  [ENZYME]  [IntEnz]
UniProtKB
 [reviewed protein(s)]  [all proteins(s)]
Reactions
KEGG reaction
R03657
EcoCyc
LEUCINE--TRNA-LIGASE-RXN
MetaCyc
LEUCINE--TRNA-LIGASE-RXN

Reaction relationships

Outgoing
no data
Incoming
no data

Citations

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