RHEA:11742          (APPROVED)

glutathione disulfide + H(+) + NADPH => 2 glutathione + NADP(+)

Last modified: 2020-05-27. Chemically balanced: yes.

2
glutathione
CHEBI:57925
chebi link
Formula: C10H16N3O6S
Charge: -1
(no structure available)
+
NADP+
CHEBI:58349
chebi link
Formula: C21H25N7O17P3
Charge: -3
(no structure available)
<=
glutathione disulfide
CHEBI:58297
chebi link
Formula: C20H30N6O12S2
Charge: -2
(no structure available)
+
H+
CHEBI:15378
chebi link
Formula: H
Charge: 1
(no structure available)
+
NADPH
CHEBI:57783
chebi link
Formula: C21H26N7O17P3
Charge: -4
(no structure available)

Same participants, different directions

RHEA:11740 2 glutathione + NADP(+) = glutathione disulfide + H(+) + NADPH
RHEA:11741 2 glutathione + NADP(+) => glutathione disulfide + H(+) + NADPH
RHEA:11743 2 glutathione + NADP(+) <=> glutathione disulfide + H(+) + NADPH

Links to other resources

Enzymes
Enzyme classification
EC 1.8.1.7  [ENZYME]  [IntEnz]
UniProtKB
 [reviewed protein(s)]  [all proteins(s)]
Reactions
KEGG reaction
R00115
EcoCyc
GLUTATHIONE-REDUCT-NADPH-RXN
MetaCyc
GLUTATHIONE-REDUCT-NADPH-RXN
MACiE
M0006
Reactome
R-HSA-3323079.1
Reactome
R-HSA-71682.3

Reaction relationships

Outgoing
no data
Incoming
no data

Citations

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