RHEA:11827          (APPROVED)

(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + 3-methyl-2-oxobutanoate + H2O <=> (6S)-5,6,7,8-tetrahydrofolate + 2-dehydropantoate

Last modified: 2018-03-02. Chemically balanced: yes.

(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate
CHEBI:15636
chebi link
Formula: C20H21N7O6
Charge: -2
(no structure available)
+
3-methyl-2-oxobutanoate
CHEBI:11851
chebi link
Formula: C5H7O3
Charge: -1
(no structure available)
+
H2O
CHEBI:15377
chebi link
Formula: H2O
Charge: 0
(no structure available)
<=>
(6S)-5,6,7,8-tetrahydrofolate
CHEBI:57453
chebi link
Formula: C19H21N7O6
Charge: -2
(no structure available)
+
2-dehydropantoate
CHEBI:11561
chebi link
Formula: C6H9O4
Charge: -1
(no structure available)

Same participants, different directions

RHEA:11824 (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + 3-methyl-2-oxobutanoate + H2O = (6S)-5,6,7,8-tetrahydrofolate + 2-dehydropantoate
RHEA:11825 (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + 3-methyl-2-oxobutanoate + H2O => (6S)-5,6,7,8-tetrahydrofolate + 2-dehydropantoate
RHEA:11826 (6S)-5,6,7,8-tetrahydrofolate + 2-dehydropantoate => (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + 3-methyl-2-oxobutanoate + H2O

Links to other resources

Enzymes
Enzyme classification
EC 2.1.2.11  [ENZYME]  [IntEnz]
UniProtKB
 [reviewed protein(s)]  [all proteins(s)]
Reactions
KEGG reaction
R01226
EcoCyc
3-CH3-2-OXOBUTANOATE-OH-CH3-XFER-RXN
MetaCyc
3-CH3-2-OXOBUTANOATE-OH-CH3-XFER-RXN

Reaction relationships

Outgoing
no data
Incoming
no data

Citations

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