RHEA:12067          (APPROVED)

5-oxopentanoate + H2O + NAD(+) <=> glutarate + 2 H(+) + NADH

Last modified: 2019-05-24. Chemically balanced: yes.

5-oxopentanoate
CHEBI:16120
chebi link
Formula: C5H7O3
Charge: -1
(no structure available)
+
H2O
CHEBI:15377
chebi link
Formula: H2O
Charge: 0
(no structure available)
+
NAD+
CHEBI:57540
chebi link
Formula: C21H26N7O14P2
Charge: -1
(no structure available)
<=>
glutarate
CHEBI:30921
chebi link
Formula: C5H6O4
Charge: -2
(no structure available)
+
2
H+
CHEBI:15378
chebi link
Formula: H
Charge: 1
(no structure available)
+
NADH
CHEBI:57945
chebi link
Formula: C21H27N7O14P2
Charge: -2
(no structure available)

Same participants, different directions

RHEA:12064 5-oxopentanoate + H2O + NAD(+) = glutarate + 2 H(+) + NADH
RHEA:12065 5-oxopentanoate + H2O + NAD(+) => glutarate + 2 H(+) + NADH
RHEA:12066 glutarate + 2 H(+) + NADH => 5-oxopentanoate + H2O + NAD(+)

Links to other resources

Enzymes
Enzyme classification
EC 1.2.1.20  [ENZYME]  [IntEnz]
UniProtKB
 [reviewed protein(s)]  [all proteins(s)]
Reactions
KEGG reaction
R02401
MetaCyc
GLUTARATE-SEMIALDEHYDE-DEHYDROGENASE-RXN

Reaction relationships

Outgoing
RHEA:12067
is a
RHEA:39042
an omega-oxo fatty acid + H2O + NAD(+) <=> a dicarboxylate + 2 H(+) + NADH
Incoming
no data

Citations

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