RHEA:12080          (APPROVED)

acetyl-CoA + H(+) + malonyl-[ACP] = 3-oxobutanoyl-[ACP] + CO2 + CoA

Last modified: 2020-02-03. Chemically balanced: yes.

acetyl-CoA
CHEBI:57288
chebi link
Formula: C23H34N7O17P3S
Charge: -4
(no structure available)
+
H+
CHEBI:15378
chebi link
Formula: H
Charge: 1
(no structure available)
+
malonyl-[ACP]
GENERIC:9623
(RHEA-COMP:9623)
(no structure available)
O-(S-malonylpantetheine-4ʼ-phosphoryl)-L-serine residue
CHEBI:78449
chebi link
Formula: C17H26N3O11PS
Charge: -2
Position: 
=
3-oxobutanoyl-[ACP]
GENERIC:9625
(RHEA-COMP:9625)
(no structure available)
O-(S-3-oxobutanoylpantetheine-4ʼ-phosphoryl)-L-serine residue
CHEBI:78450
chebi link
Formula: C18H29N3O10PS
Charge: -1
Position: 
+
CO2
CHEBI:16526
chebi link
Formula: CO2
Charge: 0
(no structure available)
+
CoA
CHEBI:57287
chebi link
Formula: C21H32N7O16P3S
Charge: -4
(no structure available)

Same participants, different directions

RHEA:12081 acetyl-CoA + H(+) + malonyl-[ACP] => 3-oxobutanoyl-[ACP] + CO2 + CoA
RHEA:12082 3-oxobutanoyl-[ACP] + CO2 + CoA => acetyl-CoA + H(+) + malonyl-[ACP]
RHEA:12083 acetyl-CoA + H(+) + malonyl-[ACP] <=> 3-oxobutanoyl-[ACP] + CO2 + CoA

Links to other resources

Enzymes
Enzyme classification
EC 2.3.1.180  [ENZYME]  [IntEnz]
UniProtKB
 [reviewed protein(s)]  [all proteins(s)]
Reactions
KEGG reaction
R10707
EcoCyc
2.3.1.180-RXN
MetaCyc
2.3.1.180-RXN

Reaction relationships

Outgoing
no data
Incoming
no data

Citations

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