RHEA:12222          (APPROVED)

4-methyl-2-oxopentanoate + H(+) + NADH + NH4(+) => H2O + L-leucine + NAD(+)

Last modified: 2018-01-25. Chemically balanced: yes.

H2O
CHEBI:15377
chebi link
Formula: H2O
Charge: 0
(no structure available)
+
L-leucine
CHEBI:57427
chebi link
Formula: C6H13NO2
Charge: 0
(no structure available)
+
NAD+
CHEBI:57540
chebi link
Formula: C21H26N7O14P2
Charge: -1
(no structure available)
<=
4-methyl-2-oxopentanoate
CHEBI:17865
chebi link
Formula: C6H9O3
Charge: -1
(no structure available)
+
H+
CHEBI:15378
chebi link
Formula: H
Charge: 1
(no structure available)
+
NADH
CHEBI:57945
chebi link
Formula: C21H27N7O14P2
Charge: -2
(no structure available)
+
NH4+
CHEBI:28938
chebi link
Formula: H4N
Charge: 1
(no structure available)

Same participants, different directions

RHEA:12220 H2O + L-leucine + NAD(+) = 4-methyl-2-oxopentanoate + H(+) + NADH + NH4(+)
RHEA:12221 H2O + L-leucine + NAD(+) => 4-methyl-2-oxopentanoate + H(+) + NADH + NH4(+)
RHEA:12223 H2O + L-leucine + NAD(+) <=> 4-methyl-2-oxopentanoate + H(+) + NADH + NH4(+)

Links to other resources

Enzymes
Enzyme classification
EC 1.4.1.9  [ENZYME]  [IntEnz]
UniProtKB
 [reviewed protein(s)]  [all proteins(s)]
Reactions
KEGG reaction
R01088
MetaCyc
LEUCINE-DEHYDROGENASE-RXN

Reaction relationships

Outgoing
no data
Incoming
no data

Citations

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