RHEA:12304          (APPROVED)

(S)-2-amino-6-oxohexanoate + H2O + NADP(+) = 2 H(+) + L-2-aminoadipate + NADPH

Last modified: 2020-02-03. Chemically balanced: yes.

(S)-2-amino-6-oxohexanoate
CHEBI:58321
chebi link
Formula: C6H11NO3
Charge: 0
(no structure available)
+
H2O
CHEBI:15377
chebi link
Formula: H2O
Charge: 0
(no structure available)
+
NADP+
CHEBI:58349
chebi link
Formula: C21H25N7O17P3
Charge: -3
(no structure available)
=
2
H+
CHEBI:15378
chebi link
Formula: H
Charge: 1
(no structure available)
+
L-2-aminoadipate
CHEBI:58672
chebi link
Formula: C6H10NO4
Charge: -1
(no structure available)
+
NADPH
CHEBI:57783
chebi link
Formula: C21H26N7O17P3
Charge: -4
(no structure available)

Same participants, different directions

RHEA:12305 (S)-2-amino-6-oxohexanoate + H2O + NADP(+) => 2 H(+) + L-2-aminoadipate + NADPH
RHEA:12306 2 H(+) + L-2-aminoadipate + NADPH => (S)-2-amino-6-oxohexanoate + H2O + NADP(+)
RHEA:12307 (S)-2-amino-6-oxohexanoate + H2O + NADP(+) <=> 2 H(+) + L-2-aminoadipate + NADPH

Comments

Multi-step reaction: RHEA:25121 and RHEA:49480.

Links to other resources

Enzymes
Enzyme classification
EC 1.2.1.31  [ENZYME]  [IntEnz]
UniProtKB
 [reviewed protein(s)]  [all proteins(s)]
Reactions
KEGG reaction
R03103
MetaCyc
1.2.1.31-RXN

Reaction relationships

Outgoing
no data
Incoming
no data

Citations

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