RHEA:12346          (APPROVED)

H(+) + L-glutamyl-tRNA(Glu) + NADPH => (S)-4-amino-5-oxopentanoate + NADP(+) + tRNA(Glu)

Last modified: 2018-03-02. Chemically balanced: yes.

(S)-4-amino-5-oxopentanoate
CHEBI:57501
chebi link
Formula: C5H9NO3
Charge: 0
(no structure available)
+
NADP+
CHEBI:58349
chebi link
Formula: C21H25N7O17P3
Charge: -3
(no structure available)
+
tRNAGlu
GENERIC:9663
(RHEA-COMP:9663)
(no structure available)
AMP 3'-end residue
CHEBI:78442
chebi link
Formula: C10H12N5O6P
Charge: -1
Position: 
<=
H+
CHEBI:15378
chebi link
Formula: H
Charge: 1
(no structure available)
+
L-glutamyl-tRNAGlu
GENERIC:9680
(RHEA-COMP:9680)
(no structure available)
3'-(L-glutamate)adenylyl group
CHEBI:78520
chebi link
Formula: C15H19N6O9P
Charge: -1
Position: 
+
NADPH
CHEBI:57783
chebi link
Formula: C21H26N7O17P3
Charge: -4
(no structure available)

Same participants, different directions

RHEA:12344 (S)-4-amino-5-oxopentanoate + NADP(+) + tRNA(Glu) = H(+) + L-glutamyl-tRNA(Glu) + NADPH
RHEA:12345 (S)-4-amino-5-oxopentanoate + NADP(+) + tRNA(Glu) => H(+) + L-glutamyl-tRNA(Glu) + NADPH
RHEA:12347 (S)-4-amino-5-oxopentanoate + NADP(+) + tRNA(Glu) <=> H(+) + L-glutamyl-tRNA(Glu) + NADPH

Links to other resources

Enzymes
Enzyme classification
EC 1.2.1.70  [ENZYME]  [IntEnz]
UniProtKB
 [reviewed protein(s)]  [all proteins(s)]
Reactions
KEGG reaction
R04109
EcoCyc
GLUTRNAREDUCT-RXN
MetaCyc
GLUTRNAREDUCT-RXN

Reaction relationships

Outgoing
no data
Incoming
no data

Citations

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