RHEA:12654          (APPROVED)

(S)-malate + NAD(+) => CO2 + NADH + pyruvate

Last modified: 2019-04-29. Chemically balanced: yes.

(S)-malate
CHEBI:15589
chebi link
Formula: C4H4O5
Charge: -2
(no structure available)
+
NAD+
CHEBI:57540
chebi link
Formula: C21H26N7O14P2
Charge: -1
(no structure available)
=>
CO2
CHEBI:16526
chebi link
Formula: CO2
Charge: 0
(no structure available)
+
NADH
CHEBI:57945
chebi link
Formula: C21H27N7O14P2
Charge: -2
(no structure available)
+
pyruvate
CHEBI:15361
chebi link
Formula: C3H3O3
Charge: -1
(no structure available)

Same participants, different directions

RHEA:12653 (S)-malate + NAD(+) = CO2 + NADH + pyruvate
RHEA:12655 CO2 + NADH + pyruvate => (S)-malate + NAD(+)
RHEA:12656 (S)-malate + NAD(+) <=> CO2 + NADH + pyruvate

Links to other resources

Enzymes
Enzyme classification
EC 1.1.1.38  [ENZYME]  [IntEnz]
Enzyme classification
EC 1.1.1.39  [ENZYME]  [IntEnz]
UniProtKB
 [reviewed protein(s)]  [all proteins(s)]
Reactions
KEGG reaction
R00214
EcoCyc
1.1.1.39-RXN
EcoCyc
MALIC-NAD-RXN
MetaCyc
1.1.1.39-RXN
MetaCyc
MALIC-NAD-RXN
Reactome
R-HSA-9012268.2

Reaction relationships

Outgoing
no data
Incoming
no data

Citations

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