RHEA:13558          (APPROVED)

ATP + glycine + L-gamma-glutamyl-L-cysteine => ADP + glutathione + H(+) + phosphate

Last modified: 2020-05-27. Chemically balanced: yes.

ATP
CHEBI:30616
chebi link
Formula: C10H12N5O13P3
Charge: -4
(no structure available)
+
glycine
CHEBI:57305
chebi link
Formula: C2H5NO2
Charge: 0
(no structure available)
+
L-γ-glutamyl-L-cysteine
CHEBI:58173
chebi link
Formula: C8H13N2O5S
Charge: -1
(no structure available)
=>
ADP
CHEBI:456216
chebi link
Formula: C10H12N5O10P2
Charge: -3
(no structure available)
+
glutathione
CHEBI:57925
chebi link
Formula: C10H16N3O6S
Charge: -1
(no structure available)
+
H+
CHEBI:15378
chebi link
Formula: H
Charge: 1
(no structure available)
+
phosphate
CHEBI:43474
chebi link
Formula: HO4P
Charge: -2
(no structure available)

Same participants, different directions

RHEA:13557 ATP + glycine + L-gamma-glutamyl-L-cysteine = ADP + glutathione + H(+) + phosphate
RHEA:13559 ADP + glutathione + H(+) + phosphate => ATP + glycine + L-gamma-glutamyl-L-cysteine
RHEA:13560 ATP + glycine + L-gamma-glutamyl-L-cysteine <=> ADP + glutathione + H(+) + phosphate

Links to other resources

Enzymes
Enzyme classification
EC 6.3.2.3  [ENZYME]  [IntEnz]
UniProtKB
 [reviewed protein(s)]  [all proteins(s)]
Reactions
KEGG reaction
R00497
EcoCyc
GLUTATHIONE-SYN-RXN
MetaCyc
GLUTATHIONE-SYN-RXN
MACiE
M0199
Reactome
R-HSA-174394.4

Reaction relationships

Outgoing
no data
Incoming
no data

Citations

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