RHEA:14005          (APPROVED)

H2O + L,L-cystathionine = 2-oxobutanoate + L-cysteine + NH4(+)

Last modified: 2020-05-27. Chemically balanced: yes.

H2O
CHEBI:15377
chebi link
Formula: H2O
Charge: 0
(no structure available)
+
L,L-cystathionine
CHEBI:58161
chebi link
Formula: C7H14N2O4S
Charge: 0
(no structure available)
=
2-oxobutanoate
CHEBI:16763
chebi link
Formula: C4H5O3
Charge: -1
(no structure available)
+
L-cysteine
CHEBI:35235
chebi link
Formula: C3H7NO2S
Charge: 0
(no structure available)
+
NH4+
CHEBI:28938
chebi link
Formula: H4N
Charge: 1
(no structure available)

Same participants, different directions

RHEA:14006 H2O + L,L-cystathionine => 2-oxobutanoate + L-cysteine + NH4(+)
RHEA:14007 2-oxobutanoate + L-cysteine + NH4(+) => H2O + L,L-cystathionine
RHEA:14008 H2O + L,L-cystathionine <=> 2-oxobutanoate + L-cysteine + NH4(+)

Comments

Multi-step reaction: RHEA:24910 + RHEA:39967 + RHEA:39975.

Links to other resources

Enzymes
Enzyme classification
EC 4.4.1.1  [ENZYME]  [IntEnz]
UniProtKB
 [reviewed protein(s)]  [all proteins(s)]
Reactions
KEGG reaction
R01001
MetaCyc
CYSTAGLY-RXN
Reactome
R-HSA-1614583.3

Reaction relationships

Outgoing
no data
Incoming
no data

Citations

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