RHEA:15423          (APPROVED)

a long-chain fatty acyl-CoA + AMP + diphosphate => a long-chain fatty acid + ATP + CoA

Last modified: 2020-04-08. Chemically balanced: yes. Qualifiers: Class of reactions

a long-chain fatty acid
CHEBI:57560
chebi link
Formula: CO2R
Charge: -1
(no structure available)
+
ATP
CHEBI:30616
chebi link
Formula: C10H12N5O13P3
Charge: -4
(no structure available)
+
CoA
CHEBI:57287
chebi link
Formula: C21H32N7O16P3S
Charge: -4
(no structure available)
<=
a long-chain fatty acyl-CoA
CHEBI:83139
chebi link
Formula: C22H31N7O17P3SR
Charge: -4
(no structure available)
+
AMP
CHEBI:456215
chebi link
Formula: C10H12N5O7P
Charge: -2
(no structure available)
+
diphosphate
CHEBI:33019
chebi link
Formula: HO7P2
Charge: -3
(no structure available)

Same participants, different directions

RHEA:15421 a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-CoA + AMP + diphosphate
RHEA:15422 a long-chain fatty acid + ATP + CoA => a long-chain fatty acyl-CoA + AMP + diphosphate
RHEA:15424 a long-chain fatty acid + ATP + CoA <=> a long-chain fatty acyl-CoA + AMP + diphosphate

Links to other resources

Enzymes
Enzyme classification
EC 6.2.1.3  [ENZYME]  [IntEnz]
UniProtKB
 [reviewed protein(s)]  [all proteins(s)]
Reactions
KEGG reaction
R00390
MetaCyc
RXN-7904

Reaction relationships

Outgoing
RHEA:15423
is a
RHEA:38885
a fatty acyl-CoA + AMP + diphosphate => a fatty acid + ATP + CoA
Incoming
RHEA:30753
AMP + diphosphate + hexadecanoyl-CoA => ATP + CoA + hexadecanoate
is a
RHEA:15423
RHEA:33609
(9Z)-octadecenoyl-CoA + AMP + diphosphate => (9Z)-octadecenoate + ATP + CoA
is a
RHEA:15423
RHEA:33617
AMP + diphosphate + octadecanoyl-CoA => ATP + CoA + octadecanoate
is a
RHEA:15423
RHEA:33621
AMP + diphosphate + tetradecanoyl-CoA => ATP + CoA + tetradecanoate
is a
RHEA:15423
RHEA:33637
AMP + diphosphate + docosanoyl-CoA => ATP + CoA + docosanoate
is a
RHEA:15423
RHEA:33645
(9Z)-tetradecenoyl-CoA + AMP + diphosphate => (9Z)-tetradecenoate + ATP + CoA
is a
RHEA:15423
RHEA:33649
(9Z)-hexadecenoyl-CoA + AMP + diphosphate => (9Z)-hexadecenoate + ATP + CoA
is a
RHEA:15423
RHEA:33653
(9Z,12Z)-octadecadienoyl-CoA + AMP + diphosphate => (9Z,12Z)-octadecadienoate + ATP + CoA
is a
RHEA:15423
RHEA:36141
(2E)-hexadecenoyl-CoA + AMP + diphosphate => (E)-hexadec-2-enoate + ATP + CoA
is a
RHEA:15423
RHEA:44078
AMP + diphosphate + pentadecanoyl-CoA => ATP + CoA + pentadecanoate
is a
RHEA:15423
RHEA:44086
AMP + diphosphate + heptadecanoyl-CoA => ATP + CoA + heptadecanoate
is a
RHEA:15423
RHEA:44094
AMP + diphosphate + nonadecanoyl-CoA => ATP + CoA + nonadecanoate
is a
RHEA:15423
RHEA:44194
2-methylhexadecanoyl-CoA + AMP + diphosphate => 2-methylhexadecanoate + ATP + CoA
is a
RHEA:15423
RHEA:44202
12-methyloctadecanoyl-CoA + AMP + diphosphate => 12-methyloctadecanoate + ATP + CoA
is a
RHEA:15423
RHEA:44206
2-hydroxyhexadecanoyl-CoA + AMP + diphosphate => 2-hydroxyhexadecanoate + ATP + CoA
is a
RHEA:15423
RHEA:44210
12-methyltridecanoyl-CoA + AMP + diphosphate => 12-methyltridecanoate + ATP + CoA
is a
RHEA:15423
RHEA:44214
3-hydroxytetradecanoyl-CoA + AMP + diphosphate => 3-hydroxytetradecanoate + ATP + CoA
is a
RHEA:15423
RHEA:44218
12-hydroxyoctadecanoyl-CoA + AMP + diphosphate => 12-hydroxyoctadecanoate + ATP + CoA
is a
RHEA:15423
RHEA:44222
15-hydroxypentadecanoyl-CoA + AMP + diphosphate => 15-hydroxypentadecanoate + ATP + CoA
is a
RHEA:15423
RHEA:44938
(9Z,12Z,15Z)-octadecatrienoyl-CoA + AMP + diphosphate => (9Z,12Z,15Z)-octadecatrienoate + ATP + CoA
is a
RHEA:15423
RHEA:46210
AMP + diphosphate + eicosanoyl-CoA => ATP + CoA + eicosanoate
is a
RHEA:15423
RHEA:52010
8,9-epoxy-(5Z,11Z,14Z)-eicosatrienoyl-CoA + AMP + diphosphate => 8,9-epoxy-(5Z,11Z,14Z)-eicosatrienoate + ATP + CoA
is a
RHEA:15423
RHEA:52014
11,12-epoxy-(5Z,8Z,14Z)-eicosatrienoyl-CoA + AMP + diphosphate => 11,12-epoxy-(5Z,8Z,14Z)-eicosatrienoate + ATP + CoA
is a
RHEA:15423
RHEA:52018
14,15-epoxy-(5Z,8Z,11Z)-eicosatrienoyl-CoA + AMP + diphosphate => 14,15-epoxy-(5Z,8Z,11Z)-eicosatrienoate + ATP + CoA
is a
RHEA:15423
RHEA:52114
12-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoyl-CoA + AMP + diphosphate => 12-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + ATP + CoA
is a
RHEA:15423

Citations

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