RHEA:19618          (APPROVED)

a 5'-(N(7)-methyl 5'-triphosphoguanosine)-(purine-ribonucleotide)-[mRNA] + S-adenosyl-L-methionine => a 5'-(N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-purine-ribonucleotide)-[mRNA] + H(+) + S-adenosyl-L-homocysteine

Last modified: 2019-01-16. Chemically balanced: yes.

a 5'-(N7-methyl 5'-triphosphoguanosine)-(purine-ribonucleotide)-[mRNA]
GENERIC:12925
(RHEA-COMP:12925)
(no structure available)
a 5'-(N7-methyl 5'-triphosphoguanosine)-(purine-ribonucleotide) residue
CHEBI:133968
chebi link
Formula: C16H22N5O17P3R
Charge: -2
Position: 
+
S-adenosyl-L-methionine
CHEBI:59789
chebi link
Formula: C15H23N6O5S
Charge: 1
(no structure available)
=>
a 5'-(N7-methyl 5'-triphosphoguanosine)-(2'-O-methyl-purine-ribonucleotide)-[mRNA]
GENERIC:12926
(RHEA-COMP:12926)
(no structure available)
a 5'-(N7-methyl 5'-triphosphoguanosine)-(2'-O-methyl-purine-ribonucleotide) residue
CHEBI:133969
chebi link
Formula: C17H24N5O17P3R
Charge: -2
Position: 
+
H+
CHEBI:15378
chebi link
Formula: H
Charge: 1
(no structure available)
+
S-adenosyl-L-homocysteine
CHEBI:57856
chebi link
Formula: C14H20N6O5S
Charge: 0
(no structure available)

Same participants, different directions

RHEA:19617 a 5'-(N(7)-methyl 5'-triphosphoguanosine)-(purine-ribonucleotide)-[mRNA] + S-adenosyl-L-methionine = a 5'-(N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-purine-ribonucleotide)-[mRNA] + H(+) + S-adenosyl-L-homocysteine
RHEA:19619 a 5'-(N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-purine-ribonucleotide)-[mRNA] + H(+) + S-adenosyl-L-homocysteine => a 5'-(N(7)-methyl 5'-triphosphoguanosine)-(purine-ribonucleotide)-[mRNA] + S-adenosyl-L-methionine
RHEA:19620 a 5'-(N(7)-methyl 5'-triphosphoguanosine)-(purine-ribonucleotide)-[mRNA] + S-adenosyl-L-methionine <=> a 5'-(N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-purine-ribonucleotide)-[mRNA] + H(+) + S-adenosyl-L-homocysteine

Links to other resources

Enzymes
Enzyme classification
EC 2.1.1.57  [ENZYME]  [IntEnz]
UniProtKB
 [reviewed protein(s)]  [all proteins(s)]
Reactions
KEGG reaction
R03922
MetaCyc
2.1.1.57-RXN

Reaction relationships

Outgoing
RHEA:19618
is a
RHEA:58957
a ribonucleotide in RNA + S-adenosyl-L-methionine => a 2'-O-methylribonucleotide in RNA + H(+) + S-adenosyl-L-homocysteine
Incoming
no data

Citations

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