Rhea - Annotated reactions database

RHEA:21292 (APPROVED)

a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+)

Last modified: 2020-02-03. Chemically balanced: yes. Qualifiers: Class of reactions

a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate)

CHEBI:58456

Formula: C11H14O19P3R2

Charge: -5

ATP

CHEBI:30616

Formula: C10H12N5O13P3

Charge: -4

a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate)

CHEBI:57836

Formula: C11H13O22P4R2

Charge: -7

ADP

CHEBI:456216

Formula: C10H12N5O10P2

Charge: -3

H⁺

CHEBI:15378

Formula: H

Charge: 1

Same participants, different directions

RHEA:21293 a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP => a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+)

RHEA:21294 a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+) => a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP

RHEA:21295 a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP <=> a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+)

Links to other resources

Enzymes

Enzyme classification

EC 2.7.1.153 [ENZYME] [IntEnz]

UniProtKB

[reviewed protein(s)] [all proteins(s)]

Reactions

KEGG reaction

R04545

MetaCyc

2.7.1.153-RXN

Reaction relationships

Outgoing

no data

Incoming

RHEA:43396

1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phospho-1D-myo-inositol 4,5-bisphosphate + ATP = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol 3,4,5-triphosphate) + ADP + H(+)

is a

RHEA:21292

RHEA:55632