RHEA:21630          (APPROVED)

acetate + androst-4-ene-3,17-dione + H2O + NADP(+) => 17alpha-hydroxyprogesterone + NADPH + O2

Last modified: 2018-12-16Chemically balanced: yes.

Formula: C21H30O3
Charge: 0
(no structure available)
+
Formula: C21H26N7O17P3
Charge: -4
(no structure available)
+
Formula: O2
Charge: 0
(no structure available)
<=
Formula: C2H3O2
Charge: -1
(no structure available)
+
Formula: C19H26O2
Charge: 0
(no structure available)
+
Formula: H2O
Charge: 0
(no structure available)
+
Formula: C21H25N7O17P3
Charge: -3
(no structure available)

Same participants, different directions

RHEA:21628 17alpha-hydroxyprogesterone + NADPH + O2 = acetate + androst-4-ene-3,17-dione + H2O + NADP(+)
RHEA:21629 17alpha-hydroxyprogesterone + NADPH + O2 => acetate + androst-4-ene-3,17-dione + H2O + NADP(+)
RHEA:21631 17alpha-hydroxyprogesterone + NADPH + O2 <=> acetate + androst-4-ene-3,17-dione + H2O + NADP(+)

Comments

Published in:
"A steroid ketone monooxygenase from Cylindrocarpon radicicola."
Katagiri, M. and Itagaki, E.
In: Müller, F. (Ed.), Chemistry and Biochemistry of Flavoenzymes, CRC Press, Florida, 1991, pp. 102–108.

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