RHEA:21740          (APPROVED)

3-mercaptopyruvate + [thioredoxin]-dithiol = [thioredoxin]-disulfide + H(+) + hydrogen sulfide + pyruvate

Last modified: 2019-10-07. Chemically balanced: yes.

3-mercaptopyruvate
CHEBI:57678
chebi link
Formula: C3H3O3S
Charge: -1
(no structure available)
+
[thioredoxin]-dithiol
GENERIC:10698
(RHEA-COMP:10698)
(no structure available)
L-cysteine residue
CHEBI:29950
chebi link
Formula: C3H5NOS
Charge: 0
Position: n
(no structure available)
L-cysteine residue
CHEBI:29950
chebi link
Formula: C3H5NOS
Charge: 0
Position: n+3
=
[thioredoxin]-disulfide
GENERIC:10700
(RHEA-COMP:10700)
(no structure available)
L-cystine residue
CHEBI:50058
chebi link
Formula: C6H8N2O2S2
Charge: 0
Position: n/n+3
+
H+
CHEBI:15378
chebi link
Formula: H
Charge: 1
(no structure available)
+
hydrogen sulfide
CHEBI:29919
chebi link
Formula: HS
Charge: -1
(no structure available)
+
pyruvate
CHEBI:15361
chebi link
Formula: C3H3O3
Charge: -1
(no structure available)

Same participants, different directions

RHEA:21741 3-mercaptopyruvate + [thioredoxin]-dithiol => [thioredoxin]-disulfide + H(+) + hydrogen sulfide + pyruvate
RHEA:21742 [thioredoxin]-disulfide + H(+) + hydrogen sulfide + pyruvate => 3-mercaptopyruvate + [thioredoxin]-dithiol
RHEA:21743 3-mercaptopyruvate + [thioredoxin]-dithiol <=> [thioredoxin]-disulfide + H(+) + hydrogen sulfide + pyruvate

Comments

Multi-step reaction: RHEA:56296 and RHEA:56300

Links to other resources

Enzymes
Enzyme classification
EC 2.8.1.2  [ENZYME]  [IntEnz]
UniProtKB
 [reviewed protein(s)]  [all proteins(s)]
Reactions
KEGG reaction
R03105
EcoCyc
MERCAPYSTRANS-RXN
MetaCyc
MERCAPYSTRANS-RXN

Reaction relationships

Outgoing
no data
Incoming
no data

Citations

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