RHEA:22062          (APPROVED)

2 5'-deoxyadenosine + [sulfur carrier]-H + biotin + 2 L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin] => [sulfur carrier]-SH + dethiobiotin + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine

Last modified: 2018-06-13. Chemically balanced: yes.

[sulfur carrier]-SH
GENERIC:14737
(RHEA-COMP:14737)
(no structure available)
thiol group
CHEBI:29917
chebi link
Formula: HS
Charge: 0
Position: 
+
dethiobiotin
CHEBI:57861
chebi link
Formula: C10H17N2O3
Charge: -1
(no structure available)
+
2
reduced [2Fe-2S]-[ferredoxin]
GENERIC:10001
(RHEA-COMP:10001)
(no structure available)
[2Fe-2S]1+
CHEBI:33738
chebi link
Formula: Fe2S2
Charge: 1
Position: 
+
2
S-adenosyl-L-methionine
CHEBI:59789
chebi link
Formula: C15H23N6O5S
Charge: 1
(no structure available)
<=
2
5'-deoxyadenosine
CHEBI:17319
chebi link
Formula: C10H13N5O3
Charge: 0
(no structure available)
+
[sulfur carrier]-H
GENERIC:14739
(RHEA-COMP:14739)
(no structure available)
H group
CHEBI:64428
chebi link
Formula: H
Charge: 0
Position: 
+
biotin
CHEBI:57586
chebi link
Formula: C10H15N2O3S
Charge: -1
(no structure available)
+
2
L-methionine
CHEBI:57844
chebi link
Formula: C5H11NO2S
Charge: 0
(no structure available)
+
2
oxidized [2Fe-2S]-[ferredoxin]
GENERIC:10000
(RHEA-COMP:10000)
(no structure available)
[2Fe-2S]2+
CHEBI:33737
chebi link
Formula: Fe2S2
Charge: 2
Position: 

Same participants, different directions

RHEA:22060 [sulfur carrier]-SH + dethiobiotin + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = 2 5'-deoxyadenosine + [sulfur carrier]-H + biotin + 2 L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin]
RHEA:22061 [sulfur carrier]-SH + dethiobiotin + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine => 2 5'-deoxyadenosine + [sulfur carrier]-H + biotin + 2 L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin]
RHEA:22063 [sulfur carrier]-SH + dethiobiotin + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine <=> 2 5'-deoxyadenosine + [sulfur carrier]-H + biotin + 2 L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin]

Links to other resources

Enzymes
Enzyme classification
EC 2.8.1.6  [ENZYME]  [IntEnz]
UniProtKB
 [reviewed protein(s)]  [all proteins(s)]
Reactions
KEGG reaction
R01078
EcoCyc
2.8.1.6-RXN
MetaCyc
2.8.1.6-RXN

Reaction relationships

Outgoing
no data
Incoming
no data

Citations

Loading...