RHEA:22497          (OBSOLETE)

H(+) + H2O + N,N-dimethylglycine + oxidized [electron-transfer flavoprotein] => formaldehyde + reduced [electron-transfer flavoprotein] + sarcosine

Last modified: 2018-01-25. Chemically balanced: yes.

H+
CHEBI:15378
chebi link
Formula: H
Charge: 1
(no structure available)
+
H2O
CHEBI:15377
chebi link
Formula: H2O
Charge: 0
(no structure available)
+
N,N-dimethylglycine
CHEBI:58251
chebi link
Formula: C4H9NO2
Charge: 0
(no structure available)
+
oxidized [electron-transfer flavoprotein]
GENERIC:10685
(RHEA-COMP:10685)
(no structure available)
FAD
CHEBI:57692
chebi link
Formula: C27H30N9O15P2
Charge: -3
Position: 
=>
formaldehyde
CHEBI:16842
chebi link
Formula: CH2O
Charge: 0
(no structure available)
+
reduced [electron-transfer flavoprotein]
GENERIC:10686
(RHEA-COMP:10686)
(no structure available)
FADH2
CHEBI:58307
chebi link
Formula: C27H33N9O15P2
Charge: -2
Position: 
+
sarcosine
CHEBI:57433
chebi link
Formula: C3H7NO2
Charge: 0
(no structure available)

Same participants, different directions

RHEA:22496 H(+) + H2O + N,N-dimethylglycine + oxidized [electron-transfer flavoprotein] = formaldehyde + reduced [electron-transfer flavoprotein] + sarcosine
RHEA:22498 formaldehyde + reduced [electron-transfer flavoprotein] + sarcosine => H(+) + H2O + N,N-dimethylglycine + oxidized [electron-transfer flavoprotein]
RHEA:22499 H(+) + H2O + N,N-dimethylglycine + oxidized [electron-transfer flavoprotein] <=> formaldehyde + reduced [electron-transfer flavoprotein] + sarcosine

Comments

The reaction has been replaced by RHEA:52856 as it has been shown that formate is not formed in vivo but that the methyl group is transferred to tetrahydrofolate

Links to other resources

Enzymes
UniProtKB
 [reviewed protein(s)]  [all proteins(s)]
Reactions
no data

Reaction relationships

Outgoing
no data
Incoming
no data

Citations

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