RHEA:24330          (APPROVED)

10-formyldihydrofolate + ADP + phosphate => 7,8-dihydrofolate + ATP + formate

Last modified: 2017-03-17. Chemically balanced: yes.

7,8-dihydrofolate
CHEBI:57451
chebi link
Formula: C19H19N7O6
Charge: -2
(no structure available)
+
ATP
CHEBI:30616
chebi link
Formula: C10H12N5O13P3
Charge: -4
(no structure available)
+
formate
CHEBI:15740
chebi link
Formula: CHO2
Charge: -1
(no structure available)
<=
10-formyldihydrofolate
CHEBI:57452
chebi link
Formula: C20H19N7O7
Charge: -2
(no structure available)
+
ADP
CHEBI:456216
chebi link
Formula: C10H12N5O10P2
Charge: -3
(no structure available)
+
phosphate
CHEBI:43474
chebi link
Formula: HO4P
Charge: -2
(no structure available)

Same participants, different directions

RHEA:24328 7,8-dihydrofolate + ATP + formate = 10-formyldihydrofolate + ADP + phosphate
RHEA:24329 7,8-dihydrofolate + ATP + formate => 10-formyldihydrofolate + ADP + phosphate
RHEA:24331 7,8-dihydrofolate + ATP + formate <=> 10-formyldihydrofolate + ADP + phosphate

Links to other resources

Enzymes
Enzyme classification
EC 6.3.4.17  [ENZYME]  [IntEnz]
UniProtKB
 [reviewed protein(s)]  [all proteins(s)]
Reactions
KEGG reaction
R02238
MetaCyc
FORMATE--DIHYDROFOLATE-LIGASE-RXN

Reaction relationships

Outgoing
no data
Incoming
no data

Citations

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