RHEA:26196          (APPROVED)

(S)-malate + ATP + CoA <=> (S)-malyl-CoA + ADP + phosphate

Last modified: 2015-07-14. Chemically balanced: yes.

(S)-malate
CHEBI:15589
chebi link
Formula: C4H4O5
Charge: -2
(no structure available)
+
ATP
CHEBI:30616
chebi link
Formula: C10H12N5O13P3
Charge: -4
(no structure available)
+
CoA
CHEBI:57287
chebi link
Formula: C21H32N7O16P3S
Charge: -4
(no structure available)
<=>
(S)-malyl-CoA
CHEBI:57317
chebi link
Formula: C25H35N7O20P3S
Charge: -5
(no structure available)
+
ADP
CHEBI:456216
chebi link
Formula: C10H12N5O10P2
Charge: -3
(no structure available)
+
phosphate
CHEBI:43474
chebi link
Formula: HO4P
Charge: -2
(no structure available)

Same participants, different directions

RHEA:26193 (S)-malate + ATP + CoA = (S)-malyl-CoA + ADP + phosphate
RHEA:26194 (S)-malate + ATP + CoA => (S)-malyl-CoA + ADP + phosphate
RHEA:26195 (S)-malyl-CoA + ADP + phosphate => (S)-malate + ATP + CoA

Links to other resources

Enzymes
Enzyme classification
EC 6.2.1.9  [ENZYME]  [IntEnz]
UniProtKB
 [reviewed protein(s)]  [all proteins(s)]
Reactions
KEGG reaction
R01256
MetaCyc
MALATE--COA-LIGASE-RXN

Reaction relationships

Outgoing
no data
Incoming
no data

Citations

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