RHEA:42423          (APPROVED)

2-oxoglutarate + L-lysine + O2 <=> (4R)-4-hydroxy-L-lysine + CO2 + succinate

Last modified: 2018-06-11Chemically balanced: yes.

Formula: C5H4O5
Charge: -2
(no structure available)
+
Formula: C6H15N2O2
Charge: 1
(no structure available)
+
Formula: O2
Charge: 0
(no structure available)
<=>
Formula: C6H15N2O3
Charge: 1
(no structure available)
+
Formula: CO2
Charge: 0
(no structure available)
+
Formula: C4H4O4
Charge: -2
(no structure available)

Same participants, different directions

RHEA:42420 2-oxoglutarate + L-lysine + O2 = (4R)-4-hydroxy-L-lysine + CO2 + succinate
RHEA:42421 2-oxoglutarate + L-lysine + O2 => (4R)-4-hydroxy-L-lysine + CO2 + succinate
RHEA:42422 (4R)-4-hydroxy-L-lysine + CO2 + succinate => 2-oxoglutarate + L-lysine + O2

Comments

submitter: Carine Vaxelaire (CEA)

Published in:
"Synthesis of mono- and dihydroxylated amino acids with new alpha-ketoglutarate-dependent dioxygenases: biocatalytic oxidation of C-H bonds."
Baud D., Saaidi P.-L., Monfleur A., Harari M., Cuccaro J., Fossey A., Besnard M., Debard A., Mariage A., Pellouin V., Petit J.-L., Salanoubat M., Weissenbach J., de Berardinis V., Zaparucha A.
ChemCatChem 6:3012-3017(2014)

Links to other resources

Enzymes Reactions

Reaction relationships

Outgoing
no data
Incoming
no data

Citations

Loading...