Rhea - Annotated reactions database

RHEA:44181 (APPROVED)

2-methylpropanoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] => (2E)-2-methylpropenoyl-CoA + reduced [electron-transfer flavoprotein]

Last modified: 2020-02-03. Chemically balanced: yes.

2-methylpropanoyl-CoA

CHEBI:57338

Formula: C25H38N7O17P3S

Charge: -4

H⁺

CHEBI:15378

Formula: H

Charge: 1

oxidized [electron-transfer flavoprotein]

GENERIC:10685

(RHEA-COMP:10685)

FAD

CHEBI:57692

Formula: C27H30N9O15P2

Charge: -3

Position:

(2E)-2-methylpropenoyl-CoA

CHEBI:62500

Formula: C25H36N7O17P3S

Charge: -4

reduced [electron-transfer flavoprotein]

GENERIC:10686

(RHEA-COMP:10686)

FADH₂

CHEBI:58307

Formula: C27H33N9O15P2

Charge: -2

Position:

Same participants, different directions

RHEA:44180 2-methylpropanoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] = (2E)-2-methylpropenoyl-CoA + reduced [electron-transfer flavoprotein]

RHEA:44182 (2E)-2-methylpropenoyl-CoA + reduced [electron-transfer flavoprotein] => 2-methylpropanoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein]

RHEA:44183 2-methylpropanoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] <=> (2E)-2-methylpropenoyl-CoA + reduced [electron-transfer flavoprotein]

Comments

Reaction catalyzed by isobutyryl-CoA dehydrogenase (ACAD-8)

Links to other resources

Enzymes

UniProtKB

[reviewed protein(s)] [all proteins(s)]

Reactions

no data

Reaction relationships

Outgoing

RHEA:44181

is a

RHEA:31096

2-methylpropanoyl-CoA + A => (2E)-2-methylpropenoyl-CoA + AH2

RHEA:44181

is a

RHEA:47197

a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] => a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]