RHEA:60924          (APPROVED)

2-oxoglutarate + N(6)-methyl-L-lysyl-[protein] + O2 = CO2 + formaldehyde + L-lysyl-[protein] + succinate

Last modified: 2019-10-07. Chemically balanced: yes.

2-oxoglutarate
CHEBI:16810
chebi link
Formula: C5H4O5
Charge: -2
(no structure available)
+
N6-methyl-L-lysyl-[protein]
GENERIC:13053
(RHEA-COMP:13053)
(no structure available)
N6-methyl-L-lysine residue
CHEBI:61929
chebi link
Formula: C7H15N2O
Charge: 1
Position: 
+
O2
CHEBI:15379
chebi link
Formula: O2
Charge: 0
(no structure available)
=
CO2
CHEBI:16526
chebi link
Formula: CO2
Charge: 0
(no structure available)
+
formaldehyde
CHEBI:16842
chebi link
Formula: CH2O
Charge: 0
(no structure available)
+
L-lysyl-[protein]
GENERIC:9752
(RHEA-COMP:9752)
(no structure available)
L-lysine residue
CHEBI:29969
chebi link
Formula: C6H13N2O
Charge: 1
Position: 
+
succinate
CHEBI:30031
chebi link
Formula: C4H4O4
Charge: -2
(no structure available)

Same participants, different directions

RHEA:60925 2-oxoglutarate + N(6)-methyl-L-lysyl-[protein] + O2 => CO2 + formaldehyde + L-lysyl-[protein] + succinate
RHEA:60926 CO2 + formaldehyde + L-lysyl-[protein] + succinate => 2-oxoglutarate + N(6)-methyl-L-lysyl-[protein] + O2
RHEA:60927 2-oxoglutarate + N(6)-methyl-L-lysyl-[protein] + O2 <=> CO2 + formaldehyde + L-lysyl-[protein] + succinate

Links to other resources

Enzymes
UniProtKB
 [reviewed protein(s)]  [all proteins(s)]
Reactions
KEGG reaction
R09511
MetaCyc
RXN-8661

Reaction relationships

Outgoing
no data
Incoming
RHEA:10784
2-oxoglutarate + N(6)-methyl-L-lysyl(36)-[histone H3] + O2 = CO2 + formaldehyde + L-lysyl(36)-[histone H3] + succinate
is a
RHEA:60924

Citations

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