Rhea results for: CHEBI:15379

Number of hits: 1937

Information:
The query resolved to the following ChEBI compounds (by name): none

Accession Equation / Hits details Other directions
RHEA:11212 indole + O2 = 2-formamidobenzaldehyde

RHEA:10404 all-trans-beta-carotene + O2 = 2 retinal

RHEA:10512 (S)-malate + O2 = H2O2 + oxaloacetate

RHEA:11288 dihydromacarpine + H(+) + O2 = H2O2 + macarpine

RHEA:11796 ecdysone + O2 = 3-dehydroecdysone + H2O2

RHEA:12384 5,6-dihydrouracil + O2 = H2O2 + uracil

RHEA:13489 (S)-canadine + H(+) + 2 O2 = berberine + 2 H2O2

RHEA:14409 cysteamine + O2 = H(+) + hypotaurine

RHEA:15369 2,3-dihydroxybenzoate + O2 = 2-carboxy-cis,cis-muconate + 2 H(+)

RHEA:15441 (S)-dihydroorotate + O2 = H2O2 + orotate

RHEA:16621 dihydrosanguinarine + H(+) + O2 = H2O2 + sanguinarine

RHEA:17853 L-sorbopyranose + O2 = 5-dehydro-D-fructose + H2O2

RHEA:18477 2,3-dihydroxybenzoate + O2 = 2-hydroxy-3-(3-oxoprop-1-enyl)but-2-enedioate + H(+)

RHEA:18513 mannitol + O2 = H2O2 + mannose

RHEA:18573 dihydrochelirubine + H(+) + O2 = chelirubine + H2O2

RHEA:19161 2 2-aminophenol + O2 = 2 6-iminocyclohexa-2,4-dienone + 2 H2O

RHEA:19441 benzene-1,2,4-triol + O2 = 3-hydroxy-cis,cis-muconate + 2 H(+)

RHEA:19445 2,3-dihydroxyindole + O2 = anthranilate + CO2 + H(+)

RHEA:21328 cholesterol + O2 = cholest-4-en-3-one + H2O2

RHEA:22216 O2 + trans-caffeate = 3-(2-carboxyethenyl)-cis,cis-muconate + 2 H(+)

RHEA:22392 (9Z,12Z)-octadecadienoate + O2 = (7S,8S,9Z,12Z)-7,8-dihydroxyoctadeca-9,12-dienoate

RHEA:23180 a secondary alcohol + O2 = a ketone + H2O2

RHEA:23564 2 columbamine + O2 = 2 berberine + 2 H2O

RHEA:24112 2 glutathione + O2 = glutathione disulfide + H2O2

RHEA:26023 8'-apo-beta-carotenol + O2 = (3E,5E)-7-hydroxy-6-methylhepta-3,5-dienal + 14'-apo-beta-carotenal

RHEA:30083 4 Cu(+) + 4 H(+) + O2 = 4 Cu(2+) + 2 H2O

RHEA:31107 3-phenylpyruvate + O2 = (2-hydroxyphenyl)acetate + CO2

RHEA:10504 7alpha-hydroxycholest-4-en-3-one + H(+) + NADPH + O2 = 7alpha,12alpha-dihydroxycholest-4-en-3-one + H2O + NADP(+)

RHEA:10548 L-arginine + O2 = 4-guanidinobutanamide + CO2 + H2O

RHEA:10648 2-hydroxycyclohexan-1-one + H(+) + NADPH + O2 = 6-hydroxyhexan-6-olide + H2O + NADP(+)

RHEA:10920 (1R,4R)-bornane-2,5-dione + H(+) + NADH + O2 = (1R,4R)-5-oxo-1,2-campholide + H2O + NAD(+)

RHEA:10956 H(+) + NADPH + O2 + trans-cinnamate = 2-coumarate + H2O + NADP(+)

RHEA:10976 H(+) + NADH + O2 + quinolin-2-ol = 5,6-dihydroquinoline-2,5,6-triol + NAD(+)

RHEA:11124 2,5-dihydroxypyridine + H2O + O2 = formate + 2 H(+) + maleamate

RHEA:11360 2 2',3,4,4',6'-pentahydroxychalcone + 2 H(+) + O2 = 2 aureusidin + 2 H2O

RHEA:11368 1-acyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphocholine + H(+) + NADH + O2 = 1-acyl-2-[(S)-12-hydroxyoleoyl]-sn-glycero-3-phosphocholine + H2O + NAD(+)

RHEA:11700 H(+) + NADPH + O2 + progesterone = H2O + NADP(+) + testosterone acetate

RHEA:11968 AH2 + kynurenate + O2 = 7,8-dihydro-7,8-dihydroxykynurenate + A

RHEA:11984 AH2 + O2 + progesterone = A + H2O + testosterone acetate

RHEA:11996 2-hydroxybiphenyl + H(+) + NADH + O2 = biphenyl-2,3-diol + H2O + NAD(+)

RHEA:12264 2',4,4',6'-tetrahydroxychalcone + H(+) + O2 = aureusidin + H2O

RHEA:12629 2-oxoglutarate + L-hyoscyamine + O2 = (6S)-6-hydroxyhyoscyamine + CO2 + succinate

RHEA:12777 2-amino-4-hydroxypteridine + O2 = 2-amino-4,7-dihydroxypteridine + chemical entity

RHEA:12809 4 catechol + 3 O2 = 2 dibenzo[1,4]dioxin-2,3-dione + 6 H2O

RHEA:13225 3beta-hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carbaldehyde + NADPH + O2 = 3beta-hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carboxylate + H2O + NADP(+)

RHEA:13229 3beta-hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carbaldehyde + NADH + O2 = 3beta-hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carboxylate + H2O + NAD(+)

RHEA:13937 4-sulfobenzoate + NADH + O2 = 3,4-dihydroxybenzoate + NAD(+) + sulfite

RHEA:14193 3-hydroxybenzoate + AH2 + O2 = 2,3-dihydroxybenzoate + A + H2O

RHEA:14437 H2O + L-lysine + O2 = 6-amino-2-oxohexanoate + H2O2 + NH4(+)

RHEA:14689 4-chlorophenylacetate + NADH + O2 = 3,4-dihydroxyphenylacetate + chloride + NAD(+)

RHEA:14897 apigenin + 3 H(+) + 2 NADPH + O2 = 2-hydroxy-2,3-dihydrogenistein + H2O + 2 NADP(+)

RHEA:14941 all-trans-antheraxanthin + H(+) + NADH + O2 = all-trans-violaxanthin + H2O + NAD(+)

RHEA:14953 H(+) + NADPH + O2 + tetradecanoyl-CoA = (11Z)-tetradecenoyl-CoA + 2 H2O + NADP(+)

RHEA:14957 H(+) + NADH + O2 + tetradecanoyl-CoA = (11Z)-tetradecenoyl-CoA + 2 H2O + NAD(+)

RHEA:15381 O2 + quercetin = 2-(3,4-dihydroxybenzoyloxy)-4,6-dihydroxybenzoate + CO

RHEA:15701 AH2 + all-trans-neurosporene + O2 = A + all-trans-lycopene + 2 H2O

RHEA:15833 (S)-4-hydroxymandelate + H(+) + O2 = 4-hydroxybenzaldehyde + CO2 + H2O2

RHEA:16133 H2O + N(1)-acetylspermine + O2 = 3-aminopropanal + H2O2 + N(1)-acetylspermidine

RHEA:16681 4-hydroxyphenylacetate + H(+) + NADH + O2 = 3,4-dihydroxyphenylacetate + H2O + NAD(+)

RHEA:16941 N-acetylindoxyl + O2 = H2O + N-acetylisatin

RHEA:16973 2-hydroxypyridine + AH2 + O2 = 2,5-dihydroxypyridine + A + H2O

RHEA:17245 3-hydroxyanthranilate + O2 = 6-imino-5-oxocyclohexa-1,3-dienecarboxylate + H2O2

RHEA:17541 an aromatic primary alcohol + O2 = an aromatic aldehyde + H2O2

RHEA:17669 3-(2-hydroxyphenyl)propanoate + H(+) + NADH + O2 = 3-(2,3-dihydroxyphenyl)propanoate + H2O + NAD(+)

RHEA:18205 AH2 + O2 + progesterone = 11alpha-hydroxyprogesterone + A + H2O

RHEA:18433 cyclohexylamine + H2O + O2 = cyclohexanone + H2O2 + NH4(+)

RHEA:18729 4,4-dimethyl-5alpha-cholest-7-en-3beta-ol + H(+) + NADPH + O2 = 4beta-hydroxymethyl-4alpha-methyl-5alpha-cholest-7-en-3beta-ol + H2O + NADP(+)

RHEA:18733 4,4-dimethyl-5alpha-cholest-7-en-3beta-ol + H(+) + NADH + O2 = 4beta-hydroxymethyl-4alpha-methyl-5alpha-cholest-7-en-3beta-ol + H2O + NAD(+)

RHEA:18917 5alpha-cholest-7-en-3beta-ol + H(+) + NADPH + O2 = cholesta-5,7-dien-3beta-ol + 2 H2O + NADP(+)

RHEA:18921 5alpha-cholest-7-en-3beta-ol + H(+) + NADH + O2 = cholesta-5,7-dien-3beta-ol + 2 H2O + NAD(+)

RHEA:19001 4beta-hydroxymethyl-4alpha-methyl-5alpha-cholest-7-en-3beta-ol + H(+) + NADPH + O2 = 3beta-hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carbaldehyde + 2 H2O + NADP(+)

RHEA:19005 4beta-hydroxymethyl-4alpha-methyl-5alpha-cholest-7-en-3beta-ol + H(+) + NADH + O2 = 3beta-hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carbaldehyde + 2 H2O + NAD(+)

RHEA:19025 H2O + L-aspartate + O2 = H2O2 + NH4(+) + oxaloacetate

RHEA:19137 17beta-estradiol + AH2 + O2 = 6beta-hydroxyestradiol-17beta + A + H2O

RHEA:19325 H(+) + NADH + O2 + quinolin-4-ol = H2O + NAD(+) + quinoline-3,4-diol

RHEA:19425 H(+) + imidazole-4-acetate + NADH + O2 = 5-hydroxyimidazole-4-acetate + H2O + NAD(+)

RHEA:19557 AH2 + O2 + pregna-4,9(11)-diene-3,20-dione = 9,11alpha-epoxypregn-4-ene-3,20-dione + A + H2O

RHEA:19561 androst-4-ene-3,17-dione + H(+) + NADPH + O2 = H2O + NADP(+) + testololactone

RHEA:19601 H(+) + NADH + O2 + orcinol = 2,3,5-trihydroxytoluene + H2O + NAD(+)

RHEA:19829 a primary alcohol + O2 = an aldehyde + H2O2

RHEA:20169 H(+) + NADPH + O2 + tetradecanoyl-CoA = (11E)-tetradecenoyl-CoA + 2 H2O + NADP(+)

RHEA:20173 H(+) + NADH + O2 + tetradecanoyl-CoA = (11E)-tetradecenoyl-CoA + 2 H2O + NAD(+)

RHEA:20449 5-amino-4-chloro-2-(2,3-dihydroxyphenyl)pyridazin-3(2H)-one + O2 = 5-amino-4-chloro-2-(2-hydroxymuconoyl)pyridazin-3(2H)-one + 2 H(+)

RHEA:20617 L-galactono-1,4-lactone + O2 = H(+) + H2O2 + L-ascorbate

RHEA:20760 AH2 + linalool + O2 = (6E)-8-hydroxylinalool + A + H2O

RHEA:21236 anthranilate + 2 H(+) + NADPH + O2 = 2,3-dihydroxybenzoate + NADP(+) + NH4(+)

RHEA:21784 H2O + L-ascorbate + O2 = 2 H(+) + L-threonate + oxalate

RHEA:21912 CoA + H(+) + O2 + pyruvate = acetyl-CoA + CO2 + H2O2

RHEA:21940 AH2 + O2 + squalene = (S)-2,3-epoxysqualene + A + H2O

RHEA:22080 H(+) + NADH + O2 + quinolin-2-ol = H2O + NAD(+) + quinoline-2,8-diol

RHEA:22196 (9Z,12Z)-octadecadienoyl-CoA + AH2 + O2 = (6Z,9Z,12Z)-octadecatrienoyl-CoA + A + 2 H2O

RHEA:22616 2 H(+) + O2 + 2 sulochrin = 2 (2R)-bisdechlorogeodin + 2 H2O

RHEA:22692 3-hydroxybenzoate + H(+) + NADH + O2 = 2,5-dihydroxybenzoate + H2O + NAD(+)

RHEA:22696 AH2 + androst-4-ene-3,17-dione + O2 = A + H2O + testololactone

RHEA:23216 benzoyl-CoA + H(+) + NADPH + O2 = 3-hydroxybenzoyl-CoA + H2O + NADP(+)

RHEA:23316 2'-deoxyuridine + 2-oxoglutarate + O2 = 2-deoxy-D-ribono-1,4-lactone + CO2 + succinate + uracil

RHEA:23400 7,8-dihydroxykynurenate + O2 = 5-(3-carboxy-3-oxoprop-1-en-1-yl)-4,6-dihydroxypyridine-2-carboxylate + H(+)

RHEA:23740 4-hydroxyphenylacetonitrile + H(+) + NADPH + O2 = 4-hydroxymandelonitrile + H2O + NADP(+)

RHEA:23756 D-arabinono-1,4-lactone + O2 = dehydro-D-arabinono-1,4-lactone + H(+) + H2O2

RHEA:24088 all-trans-zeaxanthin + H(+) + NADH + O2 = all-trans-antheraxanthin + H2O + NAD(+)

RHEA:24092 2 H(+) + O2 + 2 sulochrin = 2 (2S)-bisdechlorogeodin + 2 H2O

RHEA:24120 H(+) + leukotriene E4 + NADPH + O2 = 20-hydroxy-leukotriene E4 + H2O + NADP(+)

RHEA:24416 2,4'-dihydroxyacetophenone + O2 = 4-hydroxybenzoate + formate + 2 H(+)

RHEA:25311 glycolate + O2 = glyoxylate + H2O2

RHEA:25864 H2O + N(1)-acetylspermidine + O2 = 4-acetamidobutanal + H2O2 + propane-1,3-diamine

RHEA:27922 5-methylsulfanyl-2,3-dioxopentyl phosphate + H2O + O2 = 4-methylsulfanyl-2-oxobutanoate + formate + 2 H(+) + phosphate

RHEA:28186 aminoacetone + H2O + O2 = H2O2 + methylglyoxal + NH4(+)

RHEA:29407 2-methoxy-6-(all-trans-octaprenyl)phenol + H(+) + NADPH + O2 = 2-methoxy-6-all-trans-octaprenyl-1,4-benzoquinol + H2O + NADP(+)

RHEA:30035 3,4-dihydroxybenzoate + 2 H(+) + NADH + O2 = benzene-1,2,4-triol + CO2 + H2O + NAD(+)

RHEA:30039 3,4-dihydroxybenzoate + 2 H(+) + NADPH + O2 = benzene-1,2,4-triol + CO2 + H2O + NADP(+)

RHEA:30651 2 H2O + O2 + urate = allantoin + CO2 + H2O2

RHEA:30775 H2O + O2 + pyridoxamine = H2O2 + NH4(+) + pyridoxal

RHEA:30787 (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-phenylalanine + O2 = (6R)-L-erythro-6,7-dihydrobiopterin + H2O + L-tyrosine

RHEA:30895 H2O + O2 + propane-1,3-diamine = 3-aminopropanal + H2O2 + NH4(+)

RHEA:31127 3-O-methylgallate + O2 = 2-oxo-2H-pyran-4,6-dicarboxylate + H(+) + methanol

RHEA:31903 H(+) + indole + NADH + O2 = H2O + indolin-2-one + NAD(+)

RHEA:31923 H(+) + indolin-2-one + NADH + O2 = 3-hydroxyindolin-2-one + H2O + NAD(+)

RHEA:31931 3-hydroxyindolin-2-one + H(+) + NADH + O2 = 2-hydroxy-2H-1,4-benzoxazin-3(4H)-one + H2O + NAD(+)

RHEA:31935 2-hydroxy-2H-1,4-benzoxazin-3(4H)-one + H(+) + NADH + O2 = DIBOA + H2O + NAD(+)

RHEA:32315 4,4-dimethyl-5alpha-cholest-7-en-3beta-ol + 2 H(+) + 3 NADPH + 3 O2 = 3beta-hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carboxylate + 4 H2O + 3 NADP(+)

RHEA:32319 4,4-dimethyl-5alpha-cholest-7-en-3beta-ol + 2 H(+) + 3 NADH + 3 O2 = 3beta-hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carboxylate + 4 H2O + 3 NAD(+)

RHEA:32891 (1S,5S)-alpha-pinene + H(+) + NADH + O2 = alpha-pinene oxide + H2O + NAD(+)

RHEA:33443 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + 2 H(+) + 3 NADPH + 3 O2 = 4alpha-carboxyl-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol + 4 H2O + 3 NADP(+)

RHEA:33531 H(+) + N-acylsphinganine + NADPH + O2 = H2O + N-acyl-(4R)-hydroxysphinganine + NADP(+)

RHEA:33603 H(+) + N-hexacosanoylsphinganine + NADPH + O2 = H2O + N-(2-hydroxyhexacosanoyl)sphinganine + NADP(+)

RHEA:33659 H(+) + N-tetracosanoylsphinganine + NADPH + O2 = H2O + N-(2-hydroxytetracosanoyl)sphinganine + NADP(+)

RHEA:33667 H(+) + N-tetracosanoylphytosphingosine + NADPH + O2 = H2O + N-(2-hydroxytetracosanoyl)phytosphingosine + NADP(+)

RHEA:33675 (4S)-N-(2,3-dihydroxytetracosanoyl)-4-hydroxysphinganine + H2O + NADP(+) = H(+) + N-(2-hydroxytetracosanoyl)phytosphingosine + NADPH + O2

RHEA:34315 AH2 + all-trans-beta-carotene + O2 = A + beta-carotene 15,15' epoxide + H2O

RHEA:34687 AH2 + N-acyl-15-methylhexadecasphinganine + O2 = A + 2 H2O + N-acyl-15-methylhexadecasphing-4-enine

RHEA:34827 H(+) + N-acyl-15-methylhexadecasphinganine + NADPH + O2 = H2O + N-acyl-4-hydroxy-15-methylhexadecasphinganine + NADP(+)

RHEA:35451 cholest-4-en-3-one + 2 H(+) + 3 NADPH + 3 O2 = (25S)-3-oxocholest-4-en-26-oate + 4 H2O + 3 NADP(+)

RHEA:36075 AH2 + N-acylsphinganine + O2 = A + an N-acylsphing-4-enine + 2 H2O

RHEA:39119 (6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + O2 = (2E,6Z,9Z,12Z,15Z,18Z,21Z)-tetracosaheptaenoyl-CoA + H2O2

RHEA:39135 (6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA + O2 = (2E,6Z,9Z,12Z,15Z,18Z)-tetracosahexaenoyl-CoA + H2O2

RHEA:39763 (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + NADPH + O2 = 11,12-epoxy-(5Z,8Z,14Z)-eicosatrienoate + H2O + NADP(+)

RHEA:41504 2 H(+) + miltiradiene + 2 NADPH + 2 O2 = ferruginol + 3 H2O + 2 NADP(+)

RHEA:42472 dibenzo-p-dioxin + NADH + O2 = 2,2',3-trihydroxydiphenyl ether + H(+) + NAD(+)

RHEA:43940 cholest-4-en-3-one + H(+) + NADPH + O2 = (25S)-3-oxocholest-4-en-26-ol + H2O + NADP(+)

RHEA:43944 (25S)-3-oxocholest-4-en-26-ol + H(+) + NADPH + O2 = (25S)-3-oxocholest-4-en-26-al + 2 H2O + NADP(+)

RHEA:43948 (25S)-3-oxocholest-4-en-26-al + NADPH + O2 = (25S)-3-oxocholest-4-en-26-oate + H2O + NADP(+)

RHEA:44772 2-methoxy-6-(all-trans-hexaprenyl)phenol + H(+) + NADPH + O2 = 2-methoxy-6-all-trans-hexaprenyl-1,4-benzoquinol + H2O + NADP(+)

RHEA:46816 4,4-dimethyl-5alpha-cholest-8-en-3beta-ol + H(+) + NADPH + O2 = 4alpha-hydroxymethyl-4beta-methyl-5alpha-cholest-8-en-3beta-ol + H2O + NADP(+)

RHEA:46820 4alpha-hydroxymethyl-4beta-methyl-5alpha-cholest-8-en-3beta-ol + H(+) + NADPH + O2 = 4alpha-hydroxyformyl-4beta-methyl-5alpha-cholest-8-en-3beta-ol + 2 H2O + NADP(+)

RHEA:46824 4alpha-hydroxyformyl-4beta-methyl-5alpha-cholest-8-en-3beta-ol + NADPH + O2 = 4alpha-carboxy-4beta-methyl-5alpha-cholest-8-en-3beta-ol + H2O + NADP(+)

RHEA:46836 4alpha-methyl-5alpha-cholest-8-en-3beta-ol + H(+) + NADPH + O2 = 4alpha-hydroxymethyl-5alpha-cholest-8-en-3beta-ol + H2O + NADP(+)

RHEA:46840 4alpha-hydroxymethyl-5alpha-cholest-8-en-3beta-ol + H(+) + NADPH + O2 = 4alpha-formyl-5alpha-cholest-8-en-3beta-ol + 2 H2O + NADP(+)

RHEA:46844 4alpha-formyl-5alpha-cholest-8-en-3beta-ol + NADPH + O2 = 4alpha-carboxy-5alpha-cholest-8-ene-3beta-ol + H2O + NADP(+)

RHEA:51660 a N-(1,2-saturated acyl)sphinganine + H(+) + NADPH + O2 = H2O + N-(2-hydroxyacyl)-sphinganine + NADP(+)

RHEA:10860 3-hydroxy-2-methylpyridine-5-carboxylate + NADH + O2 = 2-(acetamidomethylene)succinate + NAD(+)

RHEA:10864 3-hydroxy-2-methylpyridine-5-carboxylate + NADPH + O2 = 2-(acetamidomethylene)succinate + NADP(+)

RHEA:11472 an N-methyl-L-amino acid + H2O + O2 = an L-alpha-amino acid + formaldehyde + H2O2

RHEA:13029 H2O + N-acetyl-D-glucosamine + O2 = H(+) + H2O2 + N-acetyl-D-glucosaminate

RHEA:18569 an aromatic aldehyde + H2O + O2 = an aromatic carboxylate + H(+) + H2O2

RHEA:18581 ethanolamine + H2O + O2 = glycolaldehyde + H2O2 + NH4(+)

RHEA:19957 2 5'-dehydroinosine + O2 = 2 9-riburonosylhypoxanthine + 2 H(+)

RHEA:21168 (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + anthranilate + O2 = (6R)-L-erythro-6,7-dihydrobiopterin + 3-hydroxyanthranilate + H2O

RHEA:21716 (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + (S)-mandelate + O2 = (6R)-L-erythro-6,7-dihydrobiopterin + (S)-4-hydroxymandelate + H2O

RHEA:23036 2 inosine + O2 = 2 5'-dehydroinosine + 2 H2O

RHEA:23200 H2O + N(6)-methyl-L-lysine + O2 = formaldehyde + H2O2 + L-lysine

RHEA:24324 6-oxocineole + H(+) + NADPH + O2 = 1,6,6-trimethyl-2,7-dioxabicyclo[3.2.2]nonan-3-one + H2O + NADP(+)

RHEA:25876 L-aspartate + O2 = H2O2 + iminosuccinate

RHEA:33247 O2 + putrescine = 1-pyrroline + H2O2 + NH4(+)

RHEA:33679 2 [Fe(II)-cytochrome b5] + 2 H(+) + N-tetracosanoylsphinganine + O2 = 2 [Fe(III)-cytochrome b5] + H2O + N-tetracosanoylphytosphingosine

RHEA:34623 (25R)-5beta-cholestane-3alpha,7alpha,12alpha,26-tetrol + H(+) + NADPH + O2 = (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al + 2 H2O + NADP(+)

RHEA:39827 2 [Fe(II)-cytochrome b5] + 2 H(+) + O2 + tetracosanoate = 2-hydroxytetracosanoate + 2 [Fe(III)-cytochrome b5] + H2O

RHEA:39831 2 [Fe(II)-cytochrome b5] + 2 H(+) + hexadecanoate + O2 = 2-hydroxyhexadecanoate + 2 [Fe(III)-cytochrome b5] + H2O

RHEA:40963 4 2-aminophenol + 3 O2 = 2 2-aminophenoxazin-3-one + 6 H2O

RHEA:46088 (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al + O2 + 2 reduced [adrenodoxin] = (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate + H2O + 2 oxidized [adrenodoxin]

RHEA:54260 2-oxoglutarate + L-asparaginyl-[protein] + O2 = (3S)-3-hydroxy-L-asparaginyl-[protein] + CO2 + succinate

RHEA:54276 2-oxoglutarate + L-aspartyl-[protein] + O2 = (3S)-3-hydroxy-L-aspartyl-[protein] + CO2 + succinate

RHEA:56744 2-oxoglutarate + L-arginyl-[protein] + O2 = (3R)-3-hydroxy-L-arginyl-[protein] + CO2 + succinate

RHEA:10156 dihydrochelirubine + O2 + reduced [NADPH--hemoprotein reductase] = 12-hydroxydihydrochelirubine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:10528 dihydrosanguinarine + O2 + reduced [NADPH--hemoprotein reductase] = 10-hydroxydihydrosanguinarine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:11072 anthranilate + 3 H(+) + NADPH + O2 = catechol + CO2 + NADP(+) + NH4(+)

RHEA:11076 anthranilate + 3 H(+) + NADH + O2 = catechol + CO2 + NAD(+) + NH4(+)

RHEA:11480 3-hydroxybenzoate + H(+) + NADPH + O2 = 3,4-dihydroxybenzoate + H2O + NADP(+)

RHEA:12797 (6S)-6-hydroxyhyoscyamine + 2-oxoglutarate + O2 = CO2 + H(+) + H2O + scopolamine + succinate

RHEA:14601 L-lysine + O2 = 5-aminopentanamide + CO2 + H2O

RHEA:16917 2,6-dihydroxypyridine + H(+) + NADH + O2 = 2,3,6-trihydroxypyridine + H2O + NAD(+)

RHEA:17197 2 3-(4-hydroxyphenyl)pyruvate + O2 = 2 4-hydroxyphenylacetate + 2 CO2

RHEA:17257 O2 + reduced [NADPH--hemoprotein reductase] + vinorine = H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + vomilenine

RHEA:20385 (2R,3R)-dihydroquercetin + H(+) + NADH + O2 = (2R,3R)-2,3-dihydrogossypetin + H2O + NAD(+)

RHEA:20389 (2R,3R)-dihydroquercetin + H(+) + NADPH + O2 = (2R,3R)-2,3-dihydrogossypetin + H2O + NADP(+)

RHEA:20545 H(+) + L-kynurenine + NADPH + O2 = 3-hydroxy-L-kynurenine + H2O + NADP(+)

RHEA:20728 H2O + L-glutamate + O2 = 2-oxoglutarate + H2O2 + NH4(+)

RHEA:21680 (2S)-2-hydroxyphytanate + O2 = 2-oxophytanate + H2O2

RHEA:22808 6-hydroxynicotinate + H2O + O2 = 2,6-dihydroxynicotinate + H2O2

RHEA:22956 1-(1,2-saturated alkyl)-2-acyl-sn-glycero-3-phosphoethanolamine + AH2 + O2 = 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + A + 2 H2O

RHEA:23724 H2O + O2 + pyridoxal = 4-pyridoxate + H(+) + H2O2

RHEA:26233 geranylgeraniol + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + plaunotol

RHEA:28238 calycosin + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] + pseudobaptigenin

RHEA:28242 O2 + pratensein + reduced [NADPH--hemoprotein reductase] = 5-hydroxypseudobaptigenin + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:28651 inosine + O2 = 9-riburonosylhypoxanthine + H(+) + H2O

RHEA:35191 noranthrone + O2 = H2O + norsolorinic acid

RHEA:40747 2-oxoglutarate + L-lysine + O2 = (3S)-3-hydroxy-L-lysine + CO2 + succinate

RHEA:40931 2-oxoglutarate + L-ornithine + O2 = (3S)-3-hydroxy-L-ornithine + CO2 + succinate

RHEA:42420 2-oxoglutarate + L-lysine + O2 = (4R)-4-hydroxy-L-lysine + CO2 + succinate

RHEA:49000 aurachin C + H(+) + NADH + O2 = 4-hydroxy-2-methyl-3-oxo-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide + H2O + NAD(+)

RHEA:49004 aurachin C + H(+) + NADPH + O2 = 4-hydroxy-2-methyl-3-oxo-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide + H2O + NADP(+)

RHEA:49008 aurachin C + H(+) + NADPH + O2 = aurachin C epoxide + H2O + NADP(+)

RHEA:49012 aurachin C + H(+) + NADH + O2 = aurachin C epoxide + H2O + NAD(+)

RHEA:10028 D-glutamate + H2O + O2 = 2-oxoglutarate + H2O2 + NH4(+)

RHEA:10608 O2 + reduced [NADPH--hemoprotein reductase] + trans-cinnamate = H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + trans-4-coumarate

RHEA:10732 ATP + D-firefly luciferin + O2 = AMP + CO2 + diphosphate + firefly oxyluciferin + hnu

RHEA:11292 2 H(+) + O2 + rifamycin B = H2O2 + rifamycin O

RHEA:11452 7-deoxyloganin + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + loganin + oxidized [NADPH--hemoprotein reductase]

RHEA:12388 formononetin + O2 + reduced [NADPH--hemoprotein reductase] = 2'-hydroxyformononetin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:13525 (1R,4R)-camphor + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[putidaredoxin] = (1R,4R,5R)-5-hydroxycamphor + H2O + 2 oxidized [2Fe-2S]-[putidaredoxin]

RHEA:14161 1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + O2 = 3-(methylsulfanyl)propanoate + CO + formate + 2 H(+)

RHEA:14749 1-hydroxy-2-naphthoate + O2 = (3Z)-4-(2-carboxyphenyl)-2-oxobut-3-enoate + H(+)

RHEA:15449 homogentisate + O2 = 4-maleylacetoacetate + H(+)

RHEA:15865 AH2 + O2 + tryptamine = 4-hydroxytryptamine + A + H2O

RHEA:16745 AH2 + O2 + phylloquinone = 2,3-epoxyphylloquinone + A + H2O

RHEA:19341 2 H(+) + O2 + octane + 2 reduced [rubredoxin] = H2O + octan-1-ol + 2 oxidized [rubredoxin]

RHEA:19673 1,2,3-trihydroxybenzene + O2 = (2Z,4E)-2-hydroxyhexa-2,4-dienedioate + 2 H(+)

RHEA:25880 2 L-dopa + O2 = 2 3-(3,4-dihydroxyphenyl)pyruvate + 2 NH4(+)

RHEA:27413 2-oxoglutarate + codeine + O2 = CO2 + formaldehyde + morphine + succinate

RHEA:27477 2-oxoglutarate + O2 + thebaine = CO2 + formaldehyde + neopinone + succinate

RHEA:27662 (S)-2-hydroxyglutarate + O2 = 2-oxoglutarate + H2O2

RHEA:32755 (S)-naringenin + 2-oxoglutarate + O2 = apigenin + CO2 + H(+) + H2O + succinate

RHEA:33515 2 5,6-dihydroxyindole + O2 = 2 H2O + 2 indole-5,6-quinone

RHEA:33911 an N-alkylglycine + H2O + O2 = an alkylamine + glyoxylate + H2O2

RHEA:34015 ergosta-5,7-dien-3betabeta-ol + H(+) + NADPH + O2 = ergosterol + 2 H2O + NADP(+)

RHEA:35831 2-oxoglutarate + kanamycin B + O2 = 2'-dehydrokanamycin A + CO2 + NH4(+) + succinate

RHEA:38971 O2 + octadecanoyl-CoA = (2E)-octadecenoyl-CoA + H2O2

RHEA:38987 nonanoyl-CoA + O2 = (2E)-nonenoyl-CoA + H2O2

RHEA:40471 (2S)-methylpentadecanoyl-CoA + O2 = 2-methyl-(2E)-pentadecenoyl-CoA + H2O2

RHEA:41440 (2-aminoethyl)phosphonate + 2-oxoglutarate + O2 = (2R)-(2-amino-1-hydroxyethyl)phosphonate + CO2 + succinate

RHEA:41532 (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-phenylalanine + O2 = (4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin + 3-hydroxy-L-phenylalanine

RHEA:43480 1-O-methyl (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = 1-O-methyl-8-hydroperoxy-(5Z,9E,11Z,14Z)-eicosatetraenoate

RHEA:47700 H(+) + ketocytochalasin + NADPH + O2 = H2O + iso-precytochalasin + NADP(+)

RHEA:47704 H(+) + iso-precytochalasin + NADPH + O2 = cytochalasin Z16 + H2O + NADP(+)

RHEA:47804 epothilone C + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = epothilone A + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]

RHEA:48752 2-oxoglutarate + O2 + validamycin A = CO2 + H(+) + succinate + validamycin B

RHEA:49052 asperlicin C + H(+) + NADH + O2 = asperlicin E + H2O + NAD(+)

RHEA:49056 asperlicin C + H(+) + NADPH + O2 = asperlicin E + H2O + NADP(+)

RHEA:50168 N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + O2 = N-(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoyl-glycine

RHEA:50172 N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-alanine + O2 = N-(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoyl-alanine

RHEA:50176 N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-gamma-aminobutanoate + O2 = N-(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoyl-gamma-aminobutanoate

RHEA:50180 N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-gamma-aminobutanoate + O2 = N-(15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl-gamma-aminobutanoate

RHEA:50184 N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-alanine + O2 = N-(15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl-alanine

RHEA:50188 N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + O2 = N-(15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl-glycine

RHEA:53792 O2 + phenylmethanethiol = benzothialdehyde + H2O2

RHEA:55648 2-oxoglutarate + O2 + validoxylamine A = CO2 + H(+) + succinate + validoxylamine B

RHEA:58712 NADH + O2 + rifampicin = H(+) + H2O + NAD(+) + rifampicin para-naphthoquinone carboxamide

RHEA:58720 (S)-nicotine + NADPH + O2 = H2O + NADP(+) + trans-(S)-nicotine N(1')-oxide

RHEA:10836 NADPH + O2 + questin = demethylsulochrin + NADP(+)

RHEA:11004 2 H(+) + NADH + O2 + salicylate = catechol + CO2 + H2O + NAD(+)

RHEA:11052 4-aminobenzoate + 2 H(+) + NADH + O2 = 4-aminophenol + CO2 + H2O + NAD(+)

RHEA:11056 4-aminobenzoate + 2 H(+) + NADPH + O2 = 4-aminophenol + CO2 + H2O + NADP(+)

RHEA:11276 4 hydroquinone + O2 = 4 benzosemiquinone + 2 H2O

RHEA:11812 H2O + methanethiol + O2 = formaldehyde + H(+) + H2O2 + hydrogen sulfide

RHEA:11976 anhydrotetracycline + H(+) + NADPH + O2 = 5a,11a-dehydrotetracycline + H2O + NADP(+)

RHEA:11992 L-pipecolate + O2 = H(+) + H2O2 + L-1-piperideine-6-carboxylate

RHEA:12633 benzoate + H(+) + NADH + O2 = (1R,6S)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate + NAD(+)

RHEA:12677 AH2 + Latia luciferin + 2 O2 = A + CO2 + formate + H(+) + H2O + hnu + oxidized Latia luciferin

RHEA:13605 2 L-ascorbate + O2 = 2 H2O + 2 L-dehydroascorbate

RHEA:13813 benzene + H(+) + NADH + O2 = cis-1,2-dihydrobenzene-1,2-diol + NAD(+)

RHEA:13821 2-oxoglutarate + glutarate + O2 = (S)-2-hydroxyglutarate + CO2 + succinate

RHEA:14237 10-deoxysarpagine + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + sarpagine

RHEA:14681 2 2-aminophenol + A + O2 = 2-aminophenoxazin-3-one + AH2 + 2 H2O

RHEA:15033 O2 + pyridoxine = H2O2 + pyridoxal

RHEA:15321 (6aR,11aR)-3,9-dihydroxypterocarpan + O2 + reduced [NADPH--hemoprotein reductase] = (6aS,11aS)-3,6a,9-trihydroxypterocarpan + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:15489 adenosine + H2O + 2 O2 = 9-riburonosyladenine + H(+) + 2 H2O2

RHEA:15909 2-oxoglutarate + O2 + taurine = aminoacetaldehyde + CO2 + H(+) + succinate + sulfite

RHEA:16033 2-oxoglutarate + gibberellin A44 + O2 = CO2 + gibberellin A19 + H(+) + succinate

RHEA:16165 L-tryptophan + O2 = CO2 + H2O + indole-3-acetamide

RHEA:16385 4-hydroxybenzoate + 2 H(+) + NADPH + O2 = CO2 + H2O + hydroquinone + NADP(+)

RHEA:16389 4-hydroxybenzoate + 2 H(+) + NADH + O2 = CO2 + H2O + hydroquinone + NAD(+)

RHEA:16513 (S)-lactate + O2 = acetate + CO2 + H2O

RHEA:16737 H(+) + NADH + O2 + toluene = (1S,2R)-3-methylcyclohexa-3,5-diene-1,2-diol + NAD(+)

RHEA:16753 Mg-13(1)-oxoprotoporphyrin 13-monomethyl ester + NADPH + O2 = 3,8-divinyl protochlorophyllide a + 2 H2O + NADP(+)

RHEA:17077 H2O + N,N-dimethylglycine + O2 = formaldehyde + H2O2 + sarcosine

RHEA:17109 FMNH2 + N-methylnicotinate + O2 = (Z)-2-((N-methylformamido)methylene)-5-hydroxybutanolactone + FMN + H(+)

RHEA:18185 adenosine + O2 = 5'-dehydroadenosine + H2O2

RHEA:18273 H2O + O2 + putrescine = 4-aminobutanal + H2O2 + NH4(+)

RHEA:18369 O2 + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + H2O2

RHEA:18465 L-dopa + O2 = 5-(L-alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde + H(+)

RHEA:18745 2 juglone + O2 = 2 3,5-dihydroxy-1,4-naphthoquinone + 2 H(+)

RHEA:18849 a 2'-unsubstituted isoflavone + O2 + reduced [NADPH--hemoprotein reductase] = a 2'-hydroxyisoflavone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:18929 AH2 + O2 + thiophene-2-carbonyl-CoA = 5-hydroxythiophene-2-carbonyl-CoA + A + H(+) + H2O

RHEA:18957 (4R)-limonene + O2 + reduced [NADPH--hemoprotein reductase] = (1R,5S)-carveol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:19241 ent-kaur-16-en-19-oate + O2 + reduced [NADPH--hemoprotein reductase] = ent-7alpha-hydroxykaur-16-en-19-oate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:19457 2-nitrophenol + 2 H(+) + 2 NADPH + O2 = catechol + H2O + 2 NADP(+) + nitrite

RHEA:19473 4-hydroxybenzoate + H(+) + NADH + O2 = 3,4-dihydroxybenzoate + H2O + NAD(+)

RHEA:20920 2,4-dichlorophenol + H(+) + NADPH + O2 = 3,5-dichlorocatechol + H2O + NADP(+)

RHEA:21688 a polyvinyl alcohol + n O2 = an oxidized polyvinyl alcohol + n H2O2

RHEA:22372 H2O + O2 + propionate 3-nitronate = 3-oxopropanoate + H(+) + H2O2 + nitrite

RHEA:22540 5'-dehydroadenosine + H2O + O2 = 9-riburonosyladenine + H(+) + H2O2

RHEA:22644 O2 + protopine + reduced [NADPH--hemoprotein reductase] = 6-hydroxyprotopine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:22700 gibberellin A12 aldehyde + O2 + reduced [NADPH--hemoprotein reductase] = gibberellin A12 + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:22760 Cypridina luciferin + O2 = CO2 + hnu + oxidized Cypridina luciferin

RHEA:22844 (6aS,11aS)-4-dimethylallyl-3,6a,9-trihydroxypterocarpan + O2 + reduced [NADPH--hemoprotein reductase] = glyceollin I + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:22904 ent-7alpha-hydroxykaur-16-en-19-oate + O2 + reduced [NADPH--hemoprotein reductase] = gibberellin A12 aldehyde + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:22960 formononetin + O2 + reduced [NADPH--hemoprotein reductase] = calycosin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:23432 (4S)-limonene + O2 + reduced [NADPH--hemoprotein reductase] = (4S)-perillyl alcohol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:24504 1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + O2 = 4-methylsulfanyl-2-oxobutanoate + formate + 2 H(+)

RHEA:24660 H(+) + L-arginine + NADPH + O2 = H2O + N(omega)-hydroxy-L-arginine + NADP(+)

RHEA:24664 2 N(omega)-hydroxy-L-arginine + NADPH + 2 O2 = H(+) + 2 H2O + 2 L-citrulline + NADP(+) + 2 nitric oxide

RHEA:25265 2-phenylethylamine + H2O + O2 = 2-phenylacetaldehyde + H2O2 + NH4(+)

RHEA:25772 2-oxoglutarate + L-asparagine + O2 = (2S,3S)-3-hydroxyasparagine + CO2 + succinate

RHEA:25816 H2O + norspermine + O2 = 3-aminopropanal + H2O2 + norspermidine

RHEA:25976 (+)-epi-isozizaene + H(+) + NADPH + O2 = (5S)-albaflavenol + H2O + NADP(+)

RHEA:25980 (5S)-albaflavenol + H(+) + NADPH + O2 = albaflavenone + 2 H2O + NADP(+)

RHEA:25984 (+)-epi-isozizaene + H(+) + NADPH + O2 = (5R)-albaflavenol + H2O + NADP(+)

RHEA:25988 (5R)-albaflavenol + H(+) + NADPH + O2 = albaflavenone + 2 H2O + NADP(+)

RHEA:25996 H2O + N(1)-acetylspermine + O2 = H2O2 + N-(3-acetamidopropyl)-4-aminobutanal + propane-1,3-diamine

RHEA:26047 (6aS,11aS)-2-dimethylallyl-3,6a,9-trihydroxypterocarpan + O2 + reduced [NADPH--hemoprotein reductase] = glyceollin II + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:26051 (6aS,11aS)-2-dimethylallyl-3,6a,9-trihydroxypterocarpan + O2 + reduced [NADPH--hemoprotein reductase] = glyceollin III + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:26164 AH2 + echinenone + O2 = 4'-hydroxyechinenone + A + H2O

RHEA:26249 H(+) + levopimaradienol + NADPH + O2 = 2 H2O + levopimaradienal + NADP(+)

RHEA:26253 H(+) + isopimara-7,15-dienol + NADPH + O2 = 2 H2O + isopimara-7,15-dienal + NADP(+)

RHEA:26257 dehydroabietadienol + H(+) + NADPH + O2 = dehydroabietadienal + 2 H2O + NADP(+)

RHEA:26293 (1'S,5'S)-averufin + NADPH + O2 = 1'-hydroxyversicolorone + H2O + NADP(+)

RHEA:26393 all-trans-zeaxanthin + 2 O2 = 2 (3R)-hydroxy-beta-ionone + 4,9-dimethyldodeca-2,4,6,8,10-pentaenedial

RHEA:26418 (3R)-3-hydroxy-8'-apo-beta-carotenal + O2 = (2E,4E,6E)-2,6-dimethylocta-2,4,6-trienedial + (3R)-all-trans-3-hydroxyretinal

RHEA:26458 ethylnitronate + FMNH2 + O2 = acetaldehyde + FMN + 2 H(+) + H2O + nitrite

RHEA:27337 2 H(+) + O2 + progesterone + reduced 2[4Fe-4S]-[ferredoxin] = 15beta-hydroxyprogesterone + H2O + oxidized 2[4Fe-4S]-[ferredoxin]

RHEA:27546 anthranilate + FADH2 + O2 = 3-hydroxyanthranilate + FAD + H(+) + H2O

RHEA:28146 geranylhydroquinone + H(+) + NADPH + O2 = 3''-hydroxy-geranylhydroquinone + H2O + NADP(+)

RHEA:28414 gamma-L-glutamylputrescine + H2O + O2 = 4-(gamma-L-glutamylamino)butanal + H2O2 + NH4(+)

RHEA:29171 a ubiquinol + 2 O2 = a ubiquinone + 2 H(+) + 2 superoxide

RHEA:29175 2 O2 + ubiquinol-8 = 2 H(+) + 2 superoxide + ubiquinone-8

RHEA:29179 a menaquinol + 2 O2 = a menaquinone + 2 H(+) + 2 superoxide

RHEA:29183 menaquinol-8 + 2 O2 = 2 H(+) + menaquinone-8 + 2 superoxide

RHEA:29311 FMNH2 + O2 + sulfoacetate = FMN + glyoxylate + 2 H(+) + H2O + sulfite

RHEA:29403 6-methoxy-3-methyl-2-all-trans-octaprenyl-1,4-benzoquinol + AH2 + O2 = 3-demethylubiquinol-8 + A + H2O

RHEA:29715 2-hydroxyethane-1-sulfonate + FMNH2 + O2 = FMN + glycolaldehyde + 2 H(+) + H2O + sulfite

RHEA:29727 ethane-1-sulfonate + FMNH2 + O2 = acetaldehyde + FMN + 2 H(+) + H2O + sulfite

RHEA:29735 butane-1-sulfonate + FMNH2 + O2 = butanal + FMN + 2 H(+) + H2O + sulfite

RHEA:31567 bisphenol A + H(+) + NADH + O2 = 2,2-bis(4-hydroxyphenyl)-1-propanol + H2O + NAD(+)

RHEA:31699 4 H(+) + 2 O2 + pentalenene + 4 reduced [2Fe-2S]-[ferredoxin] = 3 H2O + 4 oxidized [2Fe-2S]-[ferredoxin] + pentalen-13-al

RHEA:31703 2 H(+) + O2 + pentalenene + 2 reduced [2Fe-2S]-[ferredoxin] = H2O + 2 oxidized [2Fe-2S]-[ferredoxin] + pentalen-13-ol

RHEA:31707 2 H(+) + O2 + pentalen-13-ol + 2 reduced [2Fe-2S]-[ferredoxin] = 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin] + pentalen-13-al

RHEA:31971 10beta-hydroxytaxa-4(20),11-dien-5alpha-yl acetate + H(+) + NADPH + O2 = 10beta,14beta-dihydroxytaxa-4(20),11-dien-5alpha-yl acetate + H2O + NADP(+)

RHEA:31975 H(+) + NADPH + O2 + taxusin = 7beta-hydroxytaxusin + H2O + NADP(+)

RHEA:32115 2-oxoglutarate + DIBOA beta-D-glucoside + O2 = CO2 + succinate + TRIBOA beta-D-glucoside

RHEA:32127 2-oxoglutarate + L-proline + O2 = cis-4-hydroxy-L-proline + CO2 + succinate

RHEA:32439 (+)-epi-isozizaene + 2 H(+) + 2 NADPH + 2 O2 = albaflavenone + 3 H2O + 2 NADP(+)

RHEA:32499 (1R,5R)-sabinene + H(+) + NADPH + O2 = (1S,3R,5S)-sabinol + H2O + NADP(+)

RHEA:33047 (1R,4R)-camphor + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[putidaredoxin] = (+)-6-endo-hydroxycamphor + H2O + 2 oxidized [2Fe-2S]-[putidaredoxin]

RHEA:33219 ent-kaur-16-en-19-oate + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = gibberellin A12 + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]

RHEA:33283 2-hydroxycyclohexan-1-one + NADPH + O2 = 6-oxohexanoate + H2O + NADP(+)

RHEA:33463 episterol + H(+) + NADPH + O2 = ergosta-5,7,24(28)-trien-3beta-ol + 2 H2O + NADP(+)

RHEA:33699 2 [Fe(II)-cytochrome b5] + C20 sphinganine + 2 H(+) + O2 = (4R)-hydroxyeicosasphinganine + 2 [Fe(III)-cytochrome b5] + H2O

RHEA:33903 H2O + O2 + pseudooxynicotine = 4-oxo-4-(pyridin-3-yl)butanal + H2O2 + methylamine

RHEA:33907 4-(methylamino)butanoate + H2O + O2 = 4-aminobutanoate + formaldehyde + H2O2

RHEA:34011 ergosta-5,7,24(28)-trien-3beta-ol + 2 H2O + NADP(+) = ergosta-5,7-dien-3betabeta-ol + H(+) + NADPH + O2

RHEA:34143 cannabinerolate + O2 = Delta(9)-tetrahydrocannabinolate + H2O2

RHEA:34259 (+)-larreatricin + AH2 + O2 = (+)-3'-hydroxylarreatricin + A + H2O

RHEA:34283 2 L-tyrosine + O2 = 2 L-dopa

RHEA:34579 2 2-oxoglutarate + 2 O2 + pentalenolactone D = 2 CO2 + H2O + pentalenolactone F + 2 succinate

RHEA:34583 2-oxoglutarate + O2 + pentalenolactone D = CO2 + H2O + pentalenolactone E + succinate

RHEA:34587 2-oxoglutarate + O2 + pentalenolactone E = CO2 + pentalenolactone F + succinate

RHEA:34615 2-hydroxyethylphosphonate + O2 = H(+) + hydrogencarbonate + methylphosphonate

RHEA:34635 1-deoxy-11-oxopentalenate + H(+) + NADPH + O2 = H2O + NADP(+) + pentalenolactone D

RHEA:34639 1-deoxy-11-oxopentalenate + H(+) + NADPH + O2 = H2O + NADP(+) + neopentalenolactone D

RHEA:35455 5alpha-cholest-7-en-3-one + 2 H(+) + 3 NADPH + 3 O2 = (25S)-Delta7-dafachronate + 4 H2O + 3 NADP(+)

RHEA:35611 menadiol + 2 O2 = 2 H(+) + menadione + 2 superoxide

RHEA:35703 1'-hydroxyversicolorone + H(+) + NADPH + O2 = (2S,3S)-versiconal hemiacetal acetate + H2O + NADP(+)

RHEA:35707 (2S)-versicolorone + H(+) + NADPH + O2 = (3S)-versiconol acetate + H2O + NADP(+)

RHEA:35955 O2 + reduced [NADPH--hemoprotein reductase] + tryprostatin B = 6-hydroxytryprostatin B + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:35959 H(+) + NADPH + O2 + tryprostatin B = demethoxyfumitremorgin C + 2 H2O + NADP(+)

RHEA:35963 O2 + reduced [NADPH--hemoprotein reductase] + tryprostatin A = fumitremorgin C + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:35967 fumitremorgin C + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = 12alpha,13alpha-dihydroxyfumitremorgin C + 2 H(+) + 2 H2O + 2 oxidized [NADPH--hemoprotein reductase]

RHEA:35975 2-oxoglutarate + AH2 + fumitremorgin B + 2 O2 = A + CO2 + H2O + succinate + verruculogen

RHEA:36043 all-trans-8'-apo-beta-carotenal + O2 = 13-apo-beta-carotenone + 2,6-dimethyldeca-2,4,6,8-tetraenedial

RHEA:36343 2-methylsulfanyl-N(6)-(Delta(2)-isopentenyl)adenosine in tRNA + H(+) + NADPH + O2 = 2-methylsulfanyl-N(6)-(cis-4-hydroxy-Delta(2)-isopentenyl)adenosine in tRNA + H2O + NADP(+)

RHEA:36887 (8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA + AH2 + O2 = (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + A + 2 H2O

RHEA:36891 (9Z,12Z)-octadecadienoyl-CoA + AH2 + O2 = (9Z,12Z,15Z)-octadecatrienoyl-CoA + A + 2 H2O

RHEA:36935 (11E)-octadecenoyl-CoA + AH2 + O2 = (9Z,11E)-octadecadienoyl-CoA + A + 2 H2O

RHEA:36939 AH2 + O2 + tetradecanoyl-CoA = (9Z)-tetradecenoyl-CoA + A + 2 H2O

RHEA:36951 AH2 + heptadecanoyl-CoA + O2 = (9Z)-heptadecenoyl-CoA + A + 2 H2O

RHEA:36955 AH2 + O2 + pentadecanoyl-CoA = (9Z)-pentadecenoyl-CoA + A + 2 H2O

RHEA:37023 2 [Fe(II)-cytochrome b5] + 2 H(+) + hexadecanoyl-CoA + O2 = (6Z)-hexadecenoyl-CoA + 2 [Fe(III)-cytochrome b5] + 2 H2O

RHEA:37447 O2 + tetracenomycin F1 = H(+) + H2O + tetracenomycin D3

RHEA:37543 2-amino-5-chlorophenol + O2 = 2-amino-5-chloromuconate 6-semialdehyde

RHEA:37871 2-heptyl-4-quinolone + H(+) + NADH + O2 = 2-heptyl-3-hydroxy-4(1H)-quinolone + H2O + NAD(+)

RHEA:37907 (9Z)-octadecenoate + O2 = (8E,10S)-10-hydroperoxy-octadeca-8-enoate

RHEA:37919 (9Z,12Z)-octadecadienoate + O2 = (8E,10S,12Z)-10-hydroperoxyoctadeca-8,12-dienoate

RHEA:37923 (9Z,12Z,15Z)-octadecatrienoate + O2 = (8E,10S,12Z,15Z)-10-hydroperoxyoctadeca-8,12,15-trienoate

RHEA:38959 a 2,3-saturated acyl-CoA + O2 = a (2E)-enoyl-CoA + H2O2

RHEA:39983 2 [Fe(II)-cytochrome b5] + a 1,2-saturated fatty acid + 2 H(+) + O2 = 2 [Fe(III)-cytochrome b5] + a 2-hydroxy fatty acid + H2O

RHEA:40171 dodecanoyl-CoA + O2 = (2E)-dodecenoyl-CoA + H2O2

RHEA:40175 O2 + octanoyl-CoA = (2E)-octenoyl-CoA + H2O2

RHEA:40179 decanoyl-CoA + O2 = (2E)-decenoyl-CoA + H2O2

RHEA:40183 O2 + tetradecanoyl-CoA = (2E)-tetradecenoyl-CoA + H2O2

RHEA:40203 O2 + reduced [NADPH--hemoprotein reductase] + tetradecanoate = 14-hydroxytetradecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:40271 O2 + tetradecanedioyl-CoA = (2E)-tetradecenedioyl-CoA + H2O2

RHEA:40423 (7Z,10Z,13Z,16Z)-docosatetraenoyl-CoA + AH2 + O2 = (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA + A + 2 H2O

RHEA:41247 (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = 9R-hydroperoxy(5Z,7E,11Z,14Z)-eicosatetraenoate

RHEA:41340 (6Z,9Z,12Z)-octadecatrienoate + O2 = 10R-hydroperoxy-(6Z,8E,12Z)-octadecatrienoate

RHEA:41344 (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + O2 = (5Z,7Z,8Z,10E,14Z,17Z)-12-hydroperoxyeicosapentaenoate

RHEA:41448 2-oxoglutarate + L-isoleucine + O2 = (4S)-4-hydroxy-L-isoleucine + CO2 + succinate

RHEA:41452 5-methyl-1-naphthoate + H(+) + NADPH + O2 = 3-hydroxy-5-methyl-1-naphthoate + H2O + NADP(+)

RHEA:41724 dodecanoate + O2 + reduced [NADPH--hemoprotein reductase] = (11R)-hydroxydodecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:42172 (11Z)-eicosenoyl-CoA + AH2 + O2 = (8Z,11Z)-eicosadienoyl-CoA + A + 2 H2O

RHEA:42176 (9Z)-tetradecenoyl-CoA + AH2 + O2 = (9Z,12Z)-tetradecadienoyl-CoA + A + 2 H2O

RHEA:42180 (6Z,9Z,12Z)-octadecatrienoyl-CoA + AH2 + O2 = (6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoA + A + 2 H2O

RHEA:42192 (9Z)-pentadecenoyl-CoA + AH2 + O2 = (9Z,12Z)-pentadecadienoyl-CoA + A + 2 H2O

RHEA:42196 (9Z)-heptadecenoyl-CoA + AH2 + O2 = (9Z,12Z)-heptadecadienoyl-CoA + A + 2 H2O

RHEA:42460 dibenzofuran + H(+) + NADH + O2 = biphenyl-2,2',3-triol + NAD(+)

RHEA:42464 biphenyl-2,2',3-triol + O2 = 2-hydroxy-6-(2-hydroxyphenyl)-6-oxo-cis,cis-hexa-2,4-dienoate + 2 H(+)

RHEA:42828 2-hydroxy-5-methyl-1-naphthoate + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = 2,7-dihydroxy-5-methyl-1-naphthoate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]

RHEA:43104 AH2 + N-acyleicosasphinganine + O2 = A + 2 H2O + N-acyleicosasphing-4-enine

RHEA:43116 2 [Fe(II)-cytochrome b5] + 2 H(+) + N-octanoylsphinganine + O2 = 2 [Fe(III)-cytochrome b5] + H2O + N-octanoyl-4-hydroxysphinganine

RHEA:43468 (8Z,11Z,14Z)-eicosatrienoate + O2 = (8Z,10E,14Z)-12-hydroperoxyeicosatrienoate

RHEA:43476 (6Z,9Z,12Z)-octadecatrienoate + O2 = 10-hydroperoxy-(6Z,8E,12Z)-octadecatrienoate

RHEA:43836 cholesterol + H(+) + NADPH + O2 = 26-hydroxycholesterol + H2O + NADP(+)

RHEA:43844 (3beta)-hydroxy-cholest-5-en-26-al + NADPH + O2 = (3beta)-hydroxy-cholest-5-en-26-oate + H2O + NADP(+)

RHEA:43952 3,7,11,15-tetramethylhexadecanoate + H(+) + NADPH + O2 = H2O + NADP(+) + omega-hydroxy-3,7,11,15-tetramethyl-hexadecanoate

RHEA:43956 15-methylhexadecanoate + H(+) + NADPH + O2 = H2O + NADP(+) + omega-hydroxy-15-methyl-hexadecanoate

RHEA:43976 H(+) + hexadecanoate + NADPH + O2 = 14-hydroxyhexadecanoate + H2O + NADP(+)

RHEA:43980 H(+) + hexadecanoate + NADPH + O2 = 15-hydroxyhexadecanoate + H2O + NADP(+)

RHEA:43984 (2E,6E)-farnesol + H(+) + NADPH + O2 = (2E,6E)-omega-hydroxy-farnesol + H2O + NADP(+)

RHEA:43988 (2E,6E)-farnesyl diphosphate + H(+) + NADPH + O2 = (2E,6E)-omega-hydroxy-farnesyl diphosphate + H2O + NADP(+)

RHEA:43992 (2E,6E,10E)-geranylgeraniol + H(+) + NADPH + O2 = 16-hydroxy-(2E,6E,10E)-geranylgeraniol + H2O + NADP(+)

RHEA:45112 gamma-tocopherol + H(+) + NADPH + O2 = 13-hydroxy-gamma-tocopherol + H2O + NADP(+)

RHEA:45236 (25R)-3beta-hydroxy-5-cholesten-26-al + H(+) + O2 + 2 reduced [adrenodoxin] = (25R)-3beta-hydroxy-5-cholestenoate + H2O + 2 oxidized [adrenodoxin]

RHEA:45268 4'-hydroxyechinenone + AH2 + O2 = 4',4'-dihydroxyechinenone + A + H2O

RHEA:45332 7,8-dihydroneopterin + O2 = 7,8-dihydroxanthopterin + formate + glycolaldehyde + H(+)

RHEA:45700 betaine + H2O + O2 = formaldehyde + H2O2 + N,N-dimethylglycine

RHEA:46056 (11E)-octadecenoyl-CoA + 2 [Fe(II)-cytochrome b5] + 2 H(+) + O2 = (11E,13Z)-octadecadienoyl-CoA + 2 [Fe(III)-cytochrome b5] + 2 H2O

RHEA:46060 (11E)-octadecenoyl-CoA + 2 [Fe(II)-cytochrome b5] + 2 H(+) + O2 = (5Z,11E)-octadecadienoyl-CoA + 2 [Fe(III)-cytochrome b5] + 2 H2O

RHEA:46064 (11E)-octadecenoyl-CoA + 2 [Fe(II)-cytochrome b5] + 2 H(+) + O2 = (6Z,11E)-octadecadienoyl-CoA + 2 [Fe(III)-cytochrome b5] + 2 H2O

RHEA:46092 (25R)-cholest-5-ene-3beta,26-diol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = (25R)-3beta-hydroxy-5-cholesten-26-al + 2 H2O + 2 oxidized [adrenodoxin]

RHEA:46108 (2E,6E,10E)-geranylgeraniol + H(+) + 2 NADPH + 2 O2 = (2E,6E,10E)-geranylgeranate + 3 H2O + 2 NADP(+)

RHEA:46120 4beta-hydroxycholesterol + H(+) + NADPH + O2 = 4beta,7alpha-dihydroxycholesterol + H2O + NADP(+)

RHEA:46132 cholesterol + H(+) + NADPH + O2 = 25-hydroxycholesterol + H2O + NADP(+)

RHEA:46140 cholesterol + O2 + reduced [NADPH--hemoprotein reductase] = 22R-hydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:46144 cholesterol + O2 + reduced [NADPH--hemoprotein reductase] = (24R)-hydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:46200 5alpha-androstane-3beta,17beta-diol + H(+) + NADPH + O2 = 5alpha-androstane-3beta,6alpha,17beta-triol + H2O + NADP(+)

RHEA:46204 androst-5-en-3beta,17beta-diol + H(+) + NADPH + O2 = androst-5-en-3beta,7alpha,17beta-triol + H2O + NADP(+)

RHEA:46300 O2 + reduced [NADPH--hemoprotein reductase] + testosterone = 2-hydroxytestosterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:46380 7alpha-hydroxycholesterol + O2 + reduced [NADPH--hemoprotein reductase] = (24S)-7alpha-dihydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:46384 (24S)-hydroxycholesterol + O2 + reduced [NADPH--hemoprotein reductase] = 24S,25-dihydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:46388 (24S)-hydroxycholesterol + O2 + reduced [NADPH--hemoprotein reductase] = (24S,25R)-24,26-dihydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:46400 cholesterol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = (25R)-cholest-5-ene-3beta,26-diol + H2O + 2 oxidized [adrenodoxin]

RHEA:46444 (11Z)-hexadecenoyl-CoA + AH2 + O2 = (10E,12Z)-hexadecadienoyl-CoA + A + 2 H2O

RHEA:46460 22R-hydroxycholesterol + H(+) + NADPH + O2 = (22R,7alpha)-dihydroxycholesterol + H2O + NADP(+)

RHEA:46464 (24S)-25-epoxycholesterol + H(+) + NADPH + O2 = (24S,25)-epoxy-7alpha-hydroxycholesterol + H2O + NADP(+)

RHEA:46568 5-hexenoyl-[ACP] + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = 5-hexynoyl-[ACP] + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]

RHEA:46572 2 H(+) + hexanoyl-[ACP] + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = 5-hexenoyl-[ACP] + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]

RHEA:46580 O2 + reduced [NADPH--hemoprotein reductase] + vitamin D2 = 25-hydroxyvitamin D2 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:46584 1alpha-hydroxyvitamin D2 + O2 + reduced [NADPH--hemoprotein reductase] = 1alpha,25-dihydroxyvitamin D2 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:46588 calciol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = calcidiol + H2O + 2 oxidized [adrenodoxin]

RHEA:46592 alfacalcidol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = calcitriol + H2O + 2 oxidized [adrenodoxin]

RHEA:46760 2,4-dinitrotoluene + NADH + O2 = 4-methyl-5-nitrocatechol + NAD(+) + nitrite

RHEA:46768 a 1-acyl-2-hexadecanoyl-glycerolipid + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = a 1-acyl-2-[(9Z)-hexadecenoyl]-glycerolipid + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]

RHEA:46888 3-deoxy-alpha-D-manno-oct-2-ulosonate + O2 = 3,8-dideoxy-8-oxo-alpha-D-manno-octulosonate + H2O2

RHEA:47344 3beta-hydroxycholest-5-en-7-one + 2 H(+) + O2 + 2 reduced [adrenodoxin] = (25R)-3beta,26-dihydroxycholest-5-en-7-one + H2O + 2 oxidized [adrenodoxin]

RHEA:47376 (25R)-3beta,26-dihydroxycholest-5-en-7-one + 2 H(+) + O2 + 2 reduced [adrenodoxin] = (25R)-3beta-hydroxycholest-5-en-7-one-26-al + 2 H2O + 2 oxidized [adrenodoxin]

RHEA:47380 (25R)-3beta-hydroxycholest-5-en-7-one-26-al + H(+) + O2 + 2 reduced [adrenodoxin] = (25R)-3beta-hydroxycholest-5-en-7-one-26-oate + H2O + 2 oxidized [adrenodoxin]

RHEA:47808 epothilone D + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = epothilone B + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]

RHEA:47812 H(+) + N(6)-(dimethylallyl)adenosine 5'-phosphate + NADPH + O2 = 9-ribosyl-trans-zeatin 5'-phosphate + H2O + NADP(+)

RHEA:47816 H(+) + N(6)-(dimethylallyl)adenosine 5'-diphosphate + NADPH + O2 = 9-ribosyl-trans-zeatin 5'-diphosphate + H2O + NADP(+)

RHEA:47820 H(+) + N(6)-(dimethylallyl)adenosine 5'-triphosphate + NADPH + O2 = 9-ribosyl-trans-zeatin 5'-triphosphate + H2O + NADP(+)

RHEA:48576 4-chlorocatechol + O2 = 3-chloro-cis,cis-muconate + 2 H(+)

RHEA:48588 2 H2O + 2 leukotriene A4 + O2 = 2 lipoxin B4

RHEA:48624 (5Z,8Z,11Z,13E,15S)-hydroxyeicosatetraenoate + O2 = (5S)-hydroperoxy-(15S)-hydroxy-(6E,8Z,11Z,13E)-eicosatetraenoate

RHEA:48668 20-hydroxy-leukotriene B4 + O2 + reduced [NADPH--hemoprotein reductase] = 20-oxo-leukotriene B4 + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:48672 20-oxo-leukotriene B4 + O2 + reduced [NADPH--hemoprotein reductase] = 20-carboxy-leukotriene B4 + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:48704 (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + O2 = 12S-HpEPE

RHEA:48744 (-)-yatein + 2-oxoglutarate + O2 = (-)-deoxypodophyllotoxin + CO2 + H2O + succinate

RHEA:48808 (5S)-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + AH2 + O2 = (5S,15S)-dihydroxy-(6E,8Z,11Z,13E)-eicosatetraenoate + A + H2O

RHEA:48812 (5S)-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + AH2 + O2 = (5S,15R)-dihydroxy-(6E,8Z,11Z,13E)-eicosatetraenoate + A + H2O

RHEA:48816 (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + AH2 + O2 = 17R-hydroxy-(4Z,7Z,10Z,13Z,15E,19Z)-docosahexaenoate + A + H2O

RHEA:48820 (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + AH2 + O2 = 13-hydroxy-(4Z,7Z,10Z,14E,16Z,19Z)-docosahexaenoate + A + H2O

RHEA:48828 H(+) + NADPH + O2 + resorcinol = benzene-1,2,4-triol + H2O + NADP(+)

RHEA:48832 (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = 15-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate

RHEA:48844 (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = 5-hydroperoxy-(6E,8Z,11Z,14Z)-eicosatetraenoate

RHEA:48860 18-HEPE + O2 = (5S)-hydroperoxy-18-hydroxy-(7E,9E,11Z,14Z,16E)-eicosapentaenoate

RHEA:49028 (-)-bursehernin + O2 + reduced [NADPH--hemoprotein reductase] = (-)-5'-demethylyatein + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:49032 (-)-4'-desmethyl-deoxypodophyllotoxin + O2 + reduced [NADPH--hemoprotein reductase] = 4'-demethylepipodophyllotoxin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:49044 H(+) + NADH + O2 + protoasukamycin = 4-hydroxyprotoasukamycin + H2O + NAD(+)

RHEA:49272 alfacalcidol + O2 + reduced [NADPH--hemoprotein reductase] = calcitriol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:49316 beta-cryptoxanthin + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = (5R,6S)-5,6-epoxi-beta-cryptoxanthin + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]

RHEA:49380 5-HEPE + O2 + reduced [NADPH--hemoprotein reductase] = 5,20-di-HEPE + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:49384 (12R)-hydroxy-(9Z)-octadecenoate + O2 + reduced [NADPH--hemoprotein reductase] = (12R),18-dihydroxy-(9Z)-octadecenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:49684 H(+) + NADH + O2 + resorcinol = benzene-1,2,4-triol + H2O + NAD(+)

RHEA:49716 3-hydroxy-4-methylanthranilyl-[aryl-carrier protein] + H(+) + NADH + O2 = 3,5-dihydroxy-4-methylanthranilyl-[aryl-carrier protein] + H2O + NAD(+)

RHEA:49888 (1R,6R)-1,4,5,5a,6,9-hexahydrophenazine-1,6-dicarboxylate + O2 = (1R,10aS)-1,4,10,10a-tetrahydrophenazine-1,6-dicarboxylate + H2O2

RHEA:49892 (1R,10aS)-1,4,10,10a-tetrahydrophenazine-1,6-dicarboxylate + O2 = (5aS)-5,5a-dihydrophenazine-1,6-dicarboxylate + H2O2

RHEA:49900 5,10-dihydrophenazine-1,6-dicarboxylate + O2 = H2O2 + phenazine-1,6-dicarboxylate

RHEA:49904 (1R,6R)-1,4,5,5a,6,9-hexahydrophenazine-1,6-dicarboxylate + H(+) + O2 = (1R,10aS)-1,4,10,10a-tetrahydrophenazine-1-carboxylate + CO2 + H2O2

RHEA:49940 (1R,10aS)-1,4,10,10a-tetrahydrophenazine-1-carboxylate + O2 = (10aS)-10,10a-dihydrophenazine-1-carboxylate + H2O2

RHEA:49948 (1R)-1,4,5,10-tetrahydrophenazine-1-carboxylate + O2 = (10aS)-10,10a-dihydrophenazine-1-carboxylate + H2O2

RHEA:49956 5,10-dihydrophenazine 1-carboxylate + O2 = H2O2 + phenazine-1-carboxylate

RHEA:49960 (1R)-1,4,5,10-tetrahydrophenazine-1-carboxylate + H(+) + O2 = 5,10-dihydrophenazine + CO2 + H2O2

RHEA:49964 5,10-dihydrophenazine + O2 = H2O2 + phenazine

RHEA:49984 H(+) + jasmonate + NADPH + O2 = (1R,2R)-12-hydroxyjasmonate + H2O + NADP(+)

RHEA:49988 acetone + H(+) + NADPH + O2 = H2O + methyl acetate + NADP(+)

RHEA:50156 N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-taurine + O2 = N-(15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl-taurine

RHEA:50160 N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-taurine + O2 = N-(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoyl-taurine

RHEA:50196 (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + AH2 + O2 = (15S)-hydroxy-(5Z,8Z,11Z,13E,17Z)-eicosapentaenoate + A + H2O

RHEA:50200 (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + AH2 + O2 = (18S)-hydroxy-(5Z,8Z,11Z,14Z,16E)-eicosapentaenoate + A + H2O

RHEA:50204 (18S)-hydroxy-(5Z,8Z,11Z,14Z,16E)-eicosapentaenoate + O2 = (5S)-hydroperoxy-(18S)-hydroxy-(6E,8Z,11Z,14Z,16E)-eicosapentaenoate

RHEA:50256 cholesterol + O2 + reduced [NADPH--hemoprotein reductase] = 25-hydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:50264 cholesterol + O2 + reduced [NADPH--hemoprotein reductase] = 26-hydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:50276 (14R,15S)-epoxy-(5Z,8Z,11Z)-eicosatrienoate + O2 = (12S)-hydroperoxy-(14R,15S)-epoxy-(5Z,8Z,10E)-eicosatrienoate

RHEA:50280 (14R,15S)-epoxy-(5Z,8Z,11Z)-eicosatrienoate + O2 = (5S)-hydroperoxy-(14R,15S)-epoxy-(6E,8Z,11Z)-eicosatrienoate

RHEA:50284 (14S,15R)-epoxy-(5Z,8Z,11Z)-eicosatrienoate + O2 = (12S)-hydroperoxy-(14S,15R)-epoxy-(5Z,8Z,10E)-eicosatrienoate

RHEA:50288 (14S,15R)-epoxy-(5Z,8Z,11Z)-eicosatrienoate + O2 = (8S)-hydroperoxy-(14S,15R)-epoxy-(5Z,9E,11Z)-eicosatrienoate

RHEA:50296 N-[(5Z,8Z,11Z,14Z)-eicosatetraenoyl]-serotonin + O2 + reduced [NADPH--hemoprotein reductase] = 2-oxo-N-[(5Z,8Z,11Z,14Z)-eicosatetraenoyl]-serotonin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:50300 all-trans-retinol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = all-trans-4-hydroxyretinol + H2O + 2 oxidized [adrenodoxin]

RHEA:50356 4-hydroxy-6-methylpretetramide + NADPH + O2 = 4-dedimethylamino-4-oxo-anhydrotetracycline + H2O + NADP(+)

RHEA:50360 (R)-mandelonitrile + O2 = benzoyl cyanide + H2O2

RHEA:50720 FMNH2 + methanesulfinate + O2 = FMN + H(+) + H2O + methanesulfonate

RHEA:50744 2 glyphosate + O2 = 2 aminomethylphosphonate + 2 glyoxylate + 2 H(+)

RHEA:50752 2 naphthalene-1,2,4,8-tetrol + O2 = 2 3,5-dihydroxy-1,4-naphthoquinone + 2 H(+) + 2 H2O

RHEA:50868 (18R)-hydroxy-(5Z,8Z,11Z,14Z,16E)-eicosapentaenoate + O2 = (5,12,18R)-trihydroxy-(6Z,8E,10E,14Z,16E)-eicosapentaenoate

RHEA:50872 (15R)-hydroxy-(5Z,8Z,11Z,13E,17Z)-eicosapentaenoate + O2 = (5,6,15R)-trihydroxy-(7E,9E,11Z,13E,17Z)-eicosapentaenoate

RHEA:50924 (5Z,8Z,11Z,14Z)-eicosatetraenoate + 2 O2 = (8S,15S)-dihydroperoxy-(5Z,9E,11Z,13E)-eicosatetraenoate

RHEA:50928 (5Z,8Z,11Z,14Z)-eicosatetraenoate + 2 O2 = (14R,15S)-dihydroperoxy-(5Z,8Z,10E,12E)-eicosatetraenoate

RHEA:50972 (15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + O2 = (8S,15S)-dihydroperoxy-(5Z,9E,11Z,13E)-eicosatetraenoate

RHEA:51024 H(+) + NADH + O2 + toluene-4-sulfonate = 4-(hydroxymethyl)benzenesulfonate + H2O + NAD(+)

RHEA:51080 (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 + reduced [NADPH--hemoprotein reductase] = 19,20-epoxy-(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:51084 (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 + reduced [NADPH--hemoprotein reductase] = 16,17-epoxy-(4Z,7Z,10Z,13Z,19Z)-docosapentaenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:51088 (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 + reduced [NADPH--hemoprotein reductase] = 13,14-epoxy-(4Z,7Z,10Z,16Z,19Z)-docosapentaenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:51092 (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 + reduced [NADPH--hemoprotein reductase] = 10,11-epoxy-(4Z,7Z,13Z,16Z,19Z)-docosapentaenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:51096 (7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + O2 + reduced [NADPH--hemoprotein reductase] = 19,20-epoxy-(7Z,10Z,13Z,16Z)-docosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:51100 (7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + O2 + reduced [NADPH--hemoprotein reductase] = 16,17-epoxy-(7Z,10Z,13Z,19Z)-docosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:51104 (7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + O2 + reduced [NADPH--hemoprotein reductase] = 13,14-epoxy-(7Z,10Z,16Z,19Z)-docosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:51108 (7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + O2 + reduced [NADPH--hemoprotein reductase] = 10,11-epoxy-(7Z,13Z,16Z,19Z)-docosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:51112 (4Z,7Z,10Z,13Z,16Z)-docosapentaenoate + O2 + reduced [NADPH--hemoprotein reductase] = 20-hydroxy-(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:51168 (R)-adrenaline + H2O + O2 = 3,4-dihydroxymandelaldehyde + H2O2 + methylamine

RHEA:51260 4'-O-methylnorbelladine + O2 + reduced [NADPH--hemoprotein reductase] = (10bR,4aS)-noroxomaritidine + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:51264 4'-O-methylnorbelladine + O2 + reduced [NADPH--hemoprotein reductase] = (10bS,4aR)-noroxomaritidine + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:51324 (8Z,11Z,14Z)-eicosatrienoate + O2 = (8R)-hydroperoxy-(9E,11Z,14Z)-eicosatrienoate

RHEA:51328 (8Z,11Z,14Z)-eicosatrienoate + O2 = 10-hydroperoxy-(8Z,11Z,14Z)-eicosatrienoate

RHEA:51332 (8Z,11Z,14Z)-eicosatrienoate + O2 = 11-hydroperoxy-(8Z,12E,14Z)-eicosatrienoate

RHEA:51336 (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + O2 = 8-hydroperoxy-(5Z,9E,11Z,14Z,17Z)-eicosapentaenoate

RHEA:51340 (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 = 10-hydroperoxy-(4Z,7Z,11E,13Z,16Z,19Z)-docosahexaenoate

RHEA:51412 (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + O2 = (8R)-hydroperoxy-(5Z,9E,11Z,14Z,17Z)-eicosapentaenoate

RHEA:51532 H(+) + NADPH + O2 + urate = 5-hydroxyisourate + H2O + NADP(+)

RHEA:51640 (9Z,12Z)-octadecadienoate + O2 = (11R)-hydroperoxy-(9Z,12Z)-octadecadienoate

RHEA:51648 H2O + N(6)-acetyl-L-lysyl-[protein] + O2 = [protein]-(S)-2-amino-6-oxohexanoate + acetamide + H2O2

RHEA:51668 H(+) + mevastatin + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = 2 oxidized [2Fe-2S]-[ferredoxin] + pravastatin

RHEA:51792 H(+) + NADH + O2 + salicylate = 2,3-dihydroxybenzoate + H2O + NAD(+)

RHEA:51968 (18R)-hydroxy-(5Z,8Z,11Z,14Z,16E)-eicosapentaenoate + O2 = (5S)-hydroperoxy-(18R)-hydroxy-(6E,8Z,11Z,14Z,16E)-eicosapentaenoate

RHEA:52120 (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 + reduced [NADPH--hemoprotein reductase] = (19R,20S)-epoxy-(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:52124 (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 + reduced [NADPH--hemoprotein reductase] = (19S,20R)-epoxy-(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:52168 (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + O2 + reduced [NADPH--hemoprotein reductase] = 8,9-epoxy-(5Z,11Z,14Z,17Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:52172 (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + O2 + reduced [NADPH--hemoprotein reductase] = 11,12-epoxy-(5Z,8Z,14Z,17Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:52176 (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + O2 + reduced [NADPH--hemoprotein reductase] = 14,15-epoxy-(5Z,8Z,11Z,17Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:52320 O2 + reduced [NADPH--hemoprotein reductase] + tryptamine = H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + serotonin

RHEA:52520 O2 + prostaglandin E1 + reduced [NADPH--hemoprotein reductase] = 20-hydroxy prostaglandin E1 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:52524 O2 + prostaglandin A1 + reduced [NADPH--hemoprotein reductase] = 20-hydroxy prostaglandin A1 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:52824 (1R,4R)-dihydrocarvone + H(+) + NADPH + O2 = (4R,7R)-4-isopropenyl-7-methyloxepan-2-one + H2O + NADP(+)

RHEA:52828 (1S,4R)-isodihydrocarvone + H(+) + NADPH + O2 = (3S,6R)-6-isopropenyl-3-methyloxepan-2-one + H2O + NADP(+)

RHEA:52832 1-hydroxylimonen-2-one + H(+) + NADPH + O2 = 7-hydroxy-4-isopropenyl-7-methyloxepan-2-one + H2O + NADP(+)

RHEA:52908 3-dimethylallyl-4-hydroxyphenylpyruvate + O2 = 3-dimethylallyl-4-hydroxymandelate + CO2

RHEA:52912 3-dimethylallyl-4-hydroxymandelate + O2 = 3-dimethylallyl-4-hydroxybenzoate + CO2 + H2O

RHEA:53200 17beta-hydroxy-5alpha-androstan-3-one + O2 + reduced [NADPH--hemoprotein reductase] = 17beta,19-dihydroxy-3-oxo-5alpha-androstanone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:53204 17beta,19-dihydroxy-3-oxo-5alpha-androstanone + O2 + reduced [NADPH--hemoprotein reductase] = 17beta-hydroxy-3,19-dioxo-5alpha-androstanone + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:53208 daidzein + O2 + reduced [NADPH--hemoprotein reductase] = 2'-hydroxydaidzein + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:53212 17beta-hydroxy-5alpha-androstan-3-one + O2 + reduced [NADPH--hemoprotein reductase] = 17beta,18-dihydroxy-3-oxo-5alpha-androstanone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:53232 cholesta-5,24-dien-3beta-ol + O2 + reduced [NADPH--hemoprotein reductase] = (24S)-25-epoxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:53236 cholesta-5,24-dien-3beta-ol + O2 + reduced [NADPH--hemoprotein reductase] = cholesta-5,24Z-dien-3beta,27-diol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:53240 cholesta-5,7-dien-3beta-ol + O2 + reduced [NADPH--hemoprotein reductase] = cholesta-5,7-dien-3beta,25-diol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:53244 cholesta-5,7-dien-3beta-ol + O2 + reduced [NADPH--hemoprotein reductase] = cholesta-5,7-dien-3beta,24S-diol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:53260 O2 + reduced [NADPH--hemoprotein reductase] + testosterone = 1beta-hydroxytestosterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:53264 O2 + reduced [NADPH--hemoprotein reductase] + testosterone = 2beta-hydroxytestosterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:53332 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + O2 = 2-[15(S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl]-glycerol

RHEA:53408 (1S,4R)-1-hydroxylimonen-2-one + H(+) + NADPH + O2 = (4R,7R)-7-hydroxy-4-isopropenyl-7-methyloxepan-2-one + H2O + NADP(+)

RHEA:53412 (1R,4S)-1-hydroxylimonen-2-one + H(+) + NADPH + O2 = (4S,7S)-7-hydroxy-4-isopropenyl-7-methyloxepan-2-one + H2O + NADP(+)

RHEA:53608 4-hydroxyestrone + O2 = (2Z,10Z)-3-hydroxy-5,17-dioxo-4,5-secoestra-2,10-diene-3-oate + H(+)

RHEA:53652 (5S)-hydroperoxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + O2 = (5S,15S)-dihydroperoxy-(6E,8Z,11Z,13E)-eicosatetraenoate

RHEA:53656 (5S,6R)-dihydroxy-(7E,9E,11Z,14Z)-eicosatetraenoate + O2 = (5S,6R)-dihydroxy-(15S)-hydroperoxy-(7E,9E,11Z,13E)-eicosatetraenoate

RHEA:53660 (5S)-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + O2 = (5S)-hydroxy-(15S)-hydroperoxy-(6E,8Z,11Z,13E)-eicosatetraenoate

RHEA:53672 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + AH2 + O2 = 2-[(11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoyl]-sn-glycero-3-phosphoethanolamine + A + H2O

RHEA:53676 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + AH2 + O2 = 2-[(11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoyl]-sn-glycero-3-phosphocholine + A + H2O

RHEA:53680 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + AH2 + O2 = 2-[(15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl]-sn-glycero-3-phosphocholine + A + H2O

RHEA:53684 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + AH2 + O2 = 2-[(15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl]-sn-glycero-3-phosphocholine + A + H2O

RHEA:53828 2-oxoglutarate + a 5-hydroxymethyl-2'-deoxycytidine in DNA + O2 = a 5-formyl-2'-deoxycytidine in DNA + CO2 + H2O + succinate

RHEA:53832 2-oxoglutarate + a 5-formyl-2'-deoxycytidine in DNA + O2 = a 5-carboxyl-2'-deoxycytidine in DNA + CO2 + H(+) + succinate

RHEA:54024 2-oxoglutarate + L-histidyl-[ribosomal protein uL15] + O2 = (3S)-3-hydroxy-L-histidyl-[ribosomal protein uL15] + CO2 + succinate

RHEA:54088 3,4-dihydroxyphenylacetate + H(+) + NADH + O2 = 2,4,5-trihydroxyphenylacetate + H2O + NAD(+)

RHEA:54092 3,4-dihydroxyphenylacetate + H(+) + NADPH + O2 = 2,4,5-trihydroxyphenylacetate + H2O + NADP(+)

RHEA:54204 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + 2 O2 = 2-(prostaglandin G2)-sn-glycero-3-phosphoethanolamine

RHEA:54212 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + 2 O2 = 2-(prostaglandin G2)-sn-glycero-3-phosphocholine

RHEA:54264 2-oxoglutarate + L-histidyl-[ankyrin-repeat domain protein] + O2 = (3S)-3-hydroxy-L-histidyl-[ankyrin-repeat domain protein] + CO2 + succinate

RHEA:54436 2-oxoglutarate + a (2R,3S,4S)-leucoanthocyanidin + O2 = a (4S)-2,3-dehydroflavan-3,4-diol + CO2 + H(+) + H2O + succinate

RHEA:54576 2-oxoglutarate + N(1)-methyladenosine in tRNA + O2 = adenosine in tRNA + CO2 + formaldehyde + succinate

RHEA:54596 2-oxoglutarate + hexadecanoyl-CoA + O2 = 2-hydroxyhexadecanoyl-CoA + CO2 + succinate

RHEA:54600 2-oxoglutarate + O2 + octanoyl-CoA = 2-hydroxyoctanoyl-CoA + CO2 + succinate

RHEA:54604 2-oxoglutarate + decanoyl-CoA + O2 = 2-hydroxydecanoyl-CoA + CO2 + succinate

RHEA:54612 2-oxoglutarate + 3-methylbutanoyl-CoA + O2 = 2-hydroxy-3-methylbutanoyl-CoA + CO2 + succinate

RHEA:54616 2-oxoglutarate + heptadecanoyl-CoA + O2 = 2-hydroxyheptadecanoyl-CoA + CO2 + succinate

RHEA:54620 2-oxoglutarate + eicosanoyl-CoA + O2 = 2-hydroxyeicosanoyl-CoA + CO2 + succinate

RHEA:54624 2-oxoglutarate + O2 + octadecanoyl-CoA = 2-hydroxyoctadecanoyl-CoA + CO2 + succinate

RHEA:54628 2-oxoglutarate + dodecanoyl-CoA + O2 = 2-hydroxydodecanoyl-CoA + CO2 + succinate

RHEA:54632 2-oxoglutarate + O2 + tetradecanoyl-CoA = 2-hydroxytetradecanoyl-CoA + CO2 + succinate

RHEA:54808 H(+) + L-isoleucine-(+)-7-isojasmonate + NADPH + O2 = H2O + L-isoleucine-(+)-12-hydroxy-7-isojasmonate + NADP(+)

RHEA:54836 H(+) + heptan-2-one + NADPH + O2 = H2O + NADP(+) + pentyl acetate

RHEA:54840 H(+) + NADPH + O2 + octan-3-one = H2O + NADP(+) + pentyl propanoate

RHEA:54844 H(+) + hexan-3-one + NADPH + O2 = ethyl butanoate + H2O + NADP(+)

RHEA:54848 H(+) + hexan-3-one + NADPH + O2 = H2O + NADP(+) + propyl propanoate

RHEA:54852 H(+) + heptan-4-one + NADPH + O2 = H2O + NADP(+) + propyl butanoate

RHEA:54856 H(+) + NADPH + O2 + octan-3-one = ethyl hexanoate + H2O + NADP(+)

RHEA:54860 geranial + H(+) + NADPH + O2 = (1E)-2,6-dimethylhepta-1,5-dien-1-yl formate + H2O + NADP(+)

RHEA:54864 H(+) + NADPH + O2 + sulcatone = 4-methylpent-3-en-1-yl acetate + H2O + NADP(+)

RHEA:55008 (1R,4S)-1-hydroxylimonen-2-one + NADPH + O2 = (3S)-3-isopropenyl-6-oxoheptanoate + H2O + NADP(+)

RHEA:55012 (1S,4R)-1-hydroxylimonen-2-one + NADPH + O2 = (3R)-3-isopropenyl-6-oxoheptanoate + H2O + NADP(+)

RHEA:55164 a jasmonyl-L-isoleucinate + H(+) + NADPH + O2 = H2O + L-isoleucine-12-hydroxyjasmonate + NADP(+)

RHEA:55172 2-oxoglutarate + hexanoyl-CoA + O2 = 2-hydroxyhexanoyl-CoA + CO2 + succinate

RHEA:55176 2-oxoglutarate + butanoyl-CoA + O2 = 2-hydroxybutanoyl-CoA + CO2 + succinate

RHEA:55180 2-oxoglutarate + 3-methylnonanoyl-CoA + O2 = 2-hydroxy-3-methylnonanoyl-CoA + CO2 + succinate

RHEA:55184 2-oxoglutarate + 3-methylundecanoyl-CoA + O2 = 2-hydroxy-3-methylundecanoyl-CoA + CO2 + succinate

RHEA:55192 2-oxoglutarate + 3-methyldodecanoyl-CoA + O2 = 2-hydroxy-3-methyldodecanoyl-CoA + CO2 + succinate

RHEA:55376 2 a quinol + O2 = 2 a quinone + 2 H2O

RHEA:55436 ferruginol + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + salviol

RHEA:55476 2 [Fe(II)-cytochrome b5] + 2 H(+) + N-acyleicosasphinganine + O2 = 2 [Fe(III)-cytochrome b5] + H2O + N-acyl-4-hydroxyeicosasphinganine

RHEA:55484 ent-cassa-12,15-diene + O2 + reduced [NADPH--hemoprotein reductase] = ent-cassa-12,15-dien-2beta-ol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:55532 H(+) + H2O + L-phenylalanine + O2 = 2-phenylacetaldehyde + CO2 + H2O2 + NH4(+)

RHEA:55788 acetone + H(+) + NADH + O2 = H2O + hydroxyacetone + NAD(+)

RHEA:55792 butan-2-one + H(+) + NADH + O2 = 1-hydroxy-2-butanone + H2O + NAD(+)

RHEA:55796 H(+) + NADH + O2 + phenol = H2O + hydroquinone + NAD(+)

RHEA:55800 2 [Fe(II)-cytochrome b5] + 2 H(+) + N-acyleicosasphinganine + O2 = 2 [Fe(III)-cytochrome b5] + 2 H2O + N-acyleicosasphing-4-enine

RHEA:55828 cortisol + O2 + reduced [NADPH--hemoprotein reductase] = 6beta-hydroxycortisol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:55832 cortisone + O2 + reduced [NADPH--hemoprotein reductase] = 6beta-hydroxycortisone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:55904 7-chloro-L-tryptophan + chloride + FADH2 + O2 = 6,7-dichloro-L-tryptophan + FAD + 2 H2O

RHEA:56104 2 AH2 + all-trans-4,4'-diaponeurosporene + 2 O2 = 4,4'-diaponeurosporenal + 2 A + 3 H2O

RHEA:56108 genistein + O2 + reduced [NADPH--hemoprotein reductase] = 2'-hydroxygenistein + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:56468 (1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + 3 bromide + 3 FADH2 + 3 O2 = (3,4,5-tribromo-1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + 3 FAD + 6 H2O

RHEA:56472 (1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + bromide + FADH2 + O2 = (5-bromo-1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + FAD + 2 H2O

RHEA:56476 (5-bromo-1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + bromide + FADH2 + O2 = (4,5-dibromo-1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + FAD + 2 H2O

RHEA:56480 (4,5-dibromo-1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + bromide + FADH2 + O2 = (3,4,5-tribromo-1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + FAD + 2 H2O

RHEA:56704 (2S)-3-(1H-indol-3-yl)-2-isocyanopropanoate + 2-oxoglutarate + H(+) + O2 = 3-[(E)-2-isocyanovinyl]indole + 2 CO2 + H2O + succinate

RHEA:56724 AH2 + all-trans-beta-carotene + O2 = 4-hydroxy-all-trans-beta-carotene + A + H2O

RHEA:56728 4-hydroxy-all-trans-beta-carotene + AH2 + O2 = 4,4-dihydroxy-all-trans-beta-carotene + A + H2O

RHEA:56756 5 H(+) + 3 O2 + obtusifoliol + 6 reduced [2Fe-2S]-[ferredoxin] = 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + formate + 4 H2O + 6 oxidized [2Fe-2S]-[ferredoxin]

RHEA:56760 24,25-dihydrolanosterol + 5 H(+) + 3 O2 + 6 reduced [2Fe-2S]-[ferredoxin] = 4,4-dimethyl-8,14-cholestadien-3beta-ol + formate + 4 H2O + 6 oxidized [2Fe-2S]-[ferredoxin]

RHEA:56812 2-oxoglutarate + chloride + H(+) + L-threonyl-[L-threonyl-carrier protein] + O2 = 4-chloro-L-threonyl-[L-threonyl-carrier protein] + CO2 + H2O + succinate

RHEA:57016 3,6-dichloro-2-methoxybenzoate + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = 3,6-dichlorosalicylate + formaldehyde + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]

RHEA:57028 FADH2 + N-methylnicotinate + O2 = (Z)-2-((N-methylformamido)methylene)-5-hydroxybutanolactone + FAD + H(+)

RHEA:57152 2-oxoglutarate + L-lysyl-[protein] + O2 = (3S)-3-hydroxy-L-lysyl-[protein] + CO2 + succinate

RHEA:57156 2-oxoglutarate + L-lysyl-[protein] + O2 = 4-hydroxy-L-lysyl-[protein] + CO2 + succinate

RHEA:57160 2-oxoglutarate + L-arginyl-[ribosomal protein eS6] + O2 = (3R)-3-hydroxy-L-arginyl-[ribosomal protein eS6] + CO2 + succinate

RHEA:57164 2-oxoglutarate + L-arginyl-[RCC1 domain-containing protein] + O2 = (3R)-3-hydroxy-L-arginyl-[RCC1 domain-containing protein] + CO2 + succinate

RHEA:57424 guaiacol + O2 + reduced [NADH--hemoprotein reductase] = catechol + formaldehyde + H(+) + H2O + oxidized [NADH--hemoprotein reductase]

RHEA:57428 anisole + O2 + reduced [NADH--hemoprotein reductase] = formaldehyde + H(+) + H2O + oxidized [NADH--hemoprotein reductase] + phenol

RHEA:57432 3-methoxycatechol + O2 + reduced [NADH--hemoprotein reductase] = 1,2,3-trihydroxybenzene + formaldehyde + H(+) + H2O + oxidized [NADH--hemoprotein reductase]

RHEA:57436 guaethol + O2 + reduced [NADH--hemoprotein reductase] = acetaldehyde + catechol + H(+) + H2O + oxidized [NADH--hemoprotein reductase]

RHEA:57440 2-methylanisole + O2 + reduced [NADH--hemoprotein reductase] = 2-hydroxytoluene + formaldehyde + H(+) + H2O + oxidized [NADH--hemoprotein reductase]

RHEA:57560 (+)-cis-trans-nepetalactol + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = 7-deoxyloganetate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]

RHEA:57564 (+)-cis-trans-nepetalactol + O2 + reduced [NADPH--hemoprotein reductase] = 7-deoxyloganetic alcohol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:57568 7-deoxyloganetic alcohol + O2 + reduced [NADPH--hemoprotein reductase] = 7-deoxyloganetic aldehyde + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:57572 7-deoxyloganetic aldehyde + O2 + reduced [NADPH--hemoprotein reductase] = 7-deoxyloganetate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:57576 7-deoxyloganate + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + loganate + oxidized [NADPH--hemoprotein reductase]

RHEA:57764 2,6-dinitrotoluene + NADH + O2 = 3-methyl-4-nitrocatechol + NAD(+) + nitrite

RHEA:57768 2-nitrotoluene + NADH + O2 = 3-methylcatechol + NAD(+) + nitrite

RHEA:57772 3-nitrotoluene + NADH + O2 = 4-methylcatechol + NAD(+) + nitrite

RHEA:57776 2-chloro-6-nitrotoluene + NADH + O2 = 4-chloro-3-methylcatechol + NAD(+) + nitrite

RHEA:57780 2-chloro-4-nitrotoluene + NADH + O2 = 3-chloro-4-methylcatechol + NAD(+) + nitrite

RHEA:57784 1,4-dinitrobenzene + NADH + O2 = 4-nitrocatechol + H(+) + NAD(+) + nitrite

RHEA:57788 1,3-dinitrobenzene + NADH + O2 = 4-nitrocatechol + H(+) + NAD(+) + nitrite

RHEA:57792 3,4-dinitrotoluene + NADH + O2 = 4-methyl-6-nitrocatechol + NAD(+) + nitrite

RHEA:57796 4-nitrotoluene + NADH + O2 = 4-methylcatechol + NAD(+) + nitrite

RHEA:57800 2,3-dinitrotoluene + NADH + O2 = 4-methyl-3-nitrocatechol + H(+) + NAD(+) + nitrite

RHEA:57804 1-chloro-3-nitrobenzene + NADH + O2 = 4-chlorocatechol + NAD(+) + nitrite

RHEA:57808 1-chloro-3-nitrobenzene + NADH + O2 = 3-chlorocatechol + NAD(+) + nitrite

RHEA:57844 fraxetin + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + sideretin (reduced form)

RHEA:57896 2-oxoglutarate + a 5'-(N(7)-methyl 5'-triphosphoguanosine)-(N(7),2'-O-dimethyladenosine 5'-phosphate)-[mRNA] + O2 = a 5'-(N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyladenosine 5'-phosphate)-[mRNA] + CO2 + formaldehyde + succinate

RHEA:57900 2-oxoglutarate + N(6)-methyladenosine in U6 snRNA + O2 = adenosine in U6 snRNA + CO2 + formaldehyde + succinate

RHEA:57904 2-oxoglutarate + a 5'-(N(7)-methyl 5'-triphosphoguanosine)-(N(7),2'-O-dimethyladenosine 5'-phosphate) in U6 snRNA + O2 = a 5'-(N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyladenosine 5'-phosphate) in U6 snRNA + CO2 + formaldehyde + succinate

RHEA:58064 O2 + reduced [NADPH--hemoprotein reductase] + xanthotoxin = 5-hydroxyxanthotoxin + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:58124 (19S)-geissoschizine + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] + polyneuridine aldehyde

RHEA:58128 A + O2 + reduced [NADPH--hemoprotein reductase] + tetrahydroalstonine = AH2 + alstonine + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:58132 A + ajmalicine + O2 + reduced [NADPH--hemoprotein reductase] = AH2 + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] + serpentine

RHEA:58204 O2 + reduced [NADPH--hemoprotein reductase] + tetrahydroalstonine = dihydroalstonine + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:58212 ajmalicine + O2 + reduced [NADPH--hemoprotein reductase] = dihydroserpentine + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:58396 4-amino-5-hydroxy-3-all-trans-hexaprenylbenzoate + 5 H(+) + O2 + 4 reduced [2Fe-2S]-[ferredoxin] = 3,4-dihydroxy-5-all-trans-hexaprenylbenzoate + H2O + NH4(+) + 4 oxidized [2Fe-2S]-[ferredoxin]

RHEA:58488 4-(trimethylamino)butanoate + H(+) + NADH + O2 = H2O + NAD(+) + succinate semialdehyde + trimethylamine

RHEA:58496 choline + H(+) + NADH + O2 = glycolaldehyde + H2O + NAD(+) + trimethylamine

RHEA:58500 betaine + H(+) + NADH + O2 = glyoxylate + H2O + NAD(+) + trimethylamine

RHEA:58516 (19S)-geissoschizine + O2 + reduced [NADPH--hemoprotein reductase] = 15alpha-stemmadenine intermediate I + 2 H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:58520 (19S)-geissoschizine + O2 + reduced [NADPH--hemoprotein reductase] = akuammicine + formate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:58604 FAD + 2 H(+) + NADH + O2 = FADH2-C4alpha-hydroperoxide + NAD(+)

RHEA:58676 NADPH + O2 + rifamycin SV = H2O + NADP(+) + rifamycin SV para-naphthoquinone carboxamide

RHEA:58684 FAD + 2 H(+) + NADPH + O2 = FADH2-C4alpha-hydroperoxide + NADP(+)

RHEA:58688 NADH + O2 + rifamycin SV = H2O + NAD(+) + rifamycin SV para-naphthoquinone carboxamide

RHEA:58696 NADPH + O2 + rifampicin = H(+) + H2O + NADP(+) + rifampicin para-naphthoquinone carboxamide

RHEA:58784 2-oxoglutarate + a 5'-methyltriphosphate-guanosine-ribonucleotide-snRNA + O2 = a 5'-triphospho-guanosine-ribonucleotide-snRNA + CO2 + formaldehyde + H(+) + succinate

RHEA:10316 2-oxoglutarate + O2 + thymine = 5-hydroxymethyluracil + CO2 + succinate

RHEA:11148 4 Fe(2+) + 4 H(+) + O2 = 4 Fe(3+) + 2 H2O

RHEA:11648 (-)-menthol + H(+) + NADPH + O2 = 1,4-menthane-3,8-diol + H2O + NADP(+)

RHEA:12512 D-aspartate + H2O + O2 = H2O2 + NH4(+) + oxaloacetate

RHEA:14509 2-oxoglutarate + mugineate + O2 = 3-epihydroxymugineate + CO2 + H(+) + succinate

RHEA:14917 3 O2 + obtusifoliol + 3 reduced [NADPH--hemoprotein reductase] = 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + formate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]

RHEA:15157 4-hydroxyphenylacetate + H(+) + NADPH + O2 = H2O + homogentisate + NADP(+)

RHEA:15161 4-hydroxyphenylacetate + H(+) + NADH + O2 = H2O + homogentisate + NAD(+)

RHEA:15633 3,4-dihydroxyphenylacetate + O2 = 2-hydroxy-5-carboxymethylmuconate semialdehyde + H(+)

RHEA:16329 (9Z,12Z,15Z)-octadecatrienoate + O2 = (R)-2-hydroperoxy-(9Z,12Z,15Z)-octadecatrienoate

RHEA:16649 (S)-N-methylcoclaurine + O2 + reduced [NADPH--hemoprotein reductase] = (S)-3'-hydroxy-N-methylcoclaurine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:16709 (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-tryptophan + O2 = (4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin + 5-hydroxy-L-tryptophan

RHEA:17713 (R)-reticuline + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] + salutaridine

RHEA:17769 choline + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = betaine aldehyde hydrate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]

RHEA:19281 (7S)-marmesin + O2 + reduced [NADPH--hemoprotein reductase] = acetone + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] + psoralen

RHEA:19721 2 [Fe(II)-cytochrome b5] + 2 H(+) + O2 + octadecanoyl-CoA = (9Z)-octadecenoyl-CoA + 2 [Fe(III)-cytochrome b5] + 2 H2O

RHEA:19969 hydroxylamine + O2 = H(+) + H2O + nitrite

RHEA:20065 2'-deoxymugineate + 2-oxoglutarate + O2 = 3-epihydroxy-2'-deoxymugineate + CO2 + H(+) + succinate

RHEA:20149 O2 + quinine + reduced [NADPH--hemoprotein reductase] = 3-hydroxyquinine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:20357 3-phenylpropanoate + H(+) + NADH + O2 = 3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate + NAD(+)

RHEA:20541 H(+) + Mg-13(1)-hydroxyprotoporphyrin 13-monomethyl ester + NADPH + O2 = 2 H2O + Mg-13(1)-oxoprotoporphyrin 13-monomethyl ester + NADP(+)

RHEA:20585 loganin + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] + secologanin

RHEA:21340 1,2-bis(4-hydroxy-3-methoxyphenyl)ethylene + O2 = 2 4-hydroxy-3-methoxybenzaldehyde

RHEA:21376 3-(4-hydroxyphenyl)pyruvate + O2 = (S)-4-hydroxymandelate + CO2

RHEA:21456 (S)-tetrahydrocolumbamine + O2 + reduced [NADPH--hemoprotein reductase] = (S)-canadine + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:21652 2-chlorobenzoate + H(+) + NADH + O2 = catechol + chloride + CO2 + NAD(+)

RHEA:23456 (9Z,12Z)-octadecadienoate + AH2 + O2 = A + crepenynate + 2 H2O

RHEA:23576 (R)-N-methylcoclaurine + (S)-N-methylcoclaurine + O2 + reduced [NADPH--hemoprotein reductase] = berbamunine + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:23684 (S)-N-methylcanadine + O2 + reduced [NADPH--hemoprotein reductase] = allocryptopine + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:24028 2-oxoglutarate + 4-(trimethylamino)butanoate + O2 = carnitine + CO2 + succinate

RHEA:24044 3,4-dihydroxybenzoate + O2 = 4-carboxy-2-hydroxy-cis,cis-muconate 6-semialdehyde + H(+)

RHEA:24060 N-hydroxy-L-tyrosine + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + N,N-dihydroxy-L-tyrosine + oxidized [NADPH--hemoprotein reductase]

RHEA:24068 cyclohexanone + H(+) + NADPH + O2 = H2O + hexano-6-lactone + NADP(+)

RHEA:24272 H(+) + Mg-protoporphyrin IX 13-monomethyl ester + NADPH + O2 = H2O + Mg-13(1)-hydroxyprotoporphyrin 13-monomethyl ester + NADP(+)

RHEA:24785 3-(3-hydroxyphenyl)propanoate + H(+) + NADH + O2 = 3-(2,3-dihydroxyphenyl)propanoate + H2O + NAD(+)

RHEA:25005 L-tryptophan + O2 + reduced [NADPH--hemoprotein reductase] = 2 H(+) + H2O + N-hydroxy-L-tryptophan + oxidized [NADPH--hemoprotein reductase]

RHEA:25009 N-hydroxy-L-tryptophan + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + N,N-dihydroxy-L-tryptophan + oxidized [NADPH--hemoprotein reductase]

RHEA:25050 3-coumarate + H(+) + NADH + O2 = (2E)-3-(2,3-dihydroxyphenyl)prop-2-enoate + H2O + NAD(+)

RHEA:25054 (2E)-3-(2,3-dihydroxyphenyl)prop-2-enoate + O2 = (2Z,4E,7E)-2-hydroxy-6-oxonona-2,4,7-trienedioate + H(+)

RHEA:25058 H(+) + NADH + O2 + trans-cinnamate = (2E)-3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)prop-2-enoate + NAD(+)

RHEA:25972 H2O + N(8)-acetylspermidine + O2 = 4-acetamidobutanal + H2O2 + propane-1,3-diamine

RHEA:26027 H2O + N(1)-acetylspermidine + O2 = 3-aminopropanal + H2O2 + N-acetylputrescine

RHEA:26085 (4S)-limonene + H(+) + NADPH + O2 = H2O + limonene 1,2-epoxide + NADP(+)

RHEA:26089 (4S)-limonene + H(+) + NADH + O2 = H2O + limonene 1,2-epoxide + NAD(+)

RHEA:26093 (4R)-limonene + H(+) + NADH + O2 = H2O + limonene 1,2-epoxide + NAD(+)

RHEA:26097 (4R)-limonene + H(+) + NADPH + O2 = H2O + limonene 1,2-epoxide + NADP(+)

RHEA:26205 4-nitrophenol + H(+) + NADPH + O2 = 4-nitrocatechol + H2O + NADP(+)

RHEA:26385 all-trans-8'-apo-beta-carotenal + O2 = (2E,4E,6E)-2,6-dimethylocta-2,4,6-trienedial + all-trans-retinal

RHEA:27310 naphthalene-1,2-diol + O2 = 2-hydroxychromene-2-carboxylate + H(+)

RHEA:27321 3-epi-6-deoxocathasterone + O2 + reduced [NADPH--hemoprotein reductase] = 6-deoxotyphasterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:27325 (22S,24R)-22-hydroxy-5alpha-ergostan-3-one + O2 + reduced [NADPH--hemoprotein reductase] = 3-dehydro-6-deoxoteasterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:27329 H(+) + NADH + O2 + urate = 5-hydroxyisourate + H2O + NAD(+)

RHEA:27481 (S)-columbianetin + O2 + reduced [NADPH--hemoprotein reductase] = acetone + angelicin + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:27522 2,5-dihydroxypyridine + O2 = H(+) + N-formylmaleamate

RHEA:27846 (2E)-3-(3-hydroxyphenyl)prop-2-enoate + H(+) + NADH + O2 = (2E)-3-(2,3-dihydroxyphenyl)prop-2-enoate + H2O + NAD(+)

RHEA:27946 dopamine + H2O + O2 = 3,4-dihydroxyphenylacetaldehyde + H2O2 + NH4(+)

RHEA:28210 H2O + L-saccharopine + O2 = (S)-2-amino-6-oxohexanoate + H2O2 + L-glutamate

RHEA:28618 2-methylbutyronitrile + H(+) + NADPH + O2 = 2-hydroxy-2-methylbutanenitrile + H2O + NADP(+)

RHEA:28623 (-)-vetispiradiene + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + solavetivol

RHEA:28627 O2 + reduced [NADPH--hemoprotein reductase] + solavetivol = H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] + solavetivone

RHEA:29599 monacolin L carboxylate + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + monacolin J carboxylate + oxidized [NADPH--hemoprotein reductase]

RHEA:30991 beta-amyrin + O2 + reduced [NADPH--hemoprotein reductase] = 24-hydroxy-beta-amyrin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:30995 O2 + reduced [NADPH--hemoprotein reductase] + sophoradiol = H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + soyasapogenol B

RHEA:31019 4 AH2 + all-trans-4,4'-diapolycopene + 4 O2 = 4 A + all-trans-4,4'-diapolycopene-4,4'-dial + 6 H2O

RHEA:31355 dimethyl sulfide + H(+) + NADH + O2 = formaldehyde + H2O + methanethiol + NAD(+)

RHEA:31599 FMNH2 + O2 + thymine = (Z)-2-methylureidoacrylate peracid + FMN + H(+)

RHEA:31711 beta-amyrin + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = 11-oxo-beta-amyrin + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]

RHEA:31715 beta-amyrin + O2 + reduced [NADPH--hemoprotein reductase] = 11alpha-hydroxy-beta-amyrin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:31719 11alpha-hydroxy-beta-amyrin + O2 + reduced [NADPH--hemoprotein reductase] = 11-oxo-beta-amyrin + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:31731 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + FMNH2 + O2 = 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + FMN + H(+) + H2O

RHEA:31899 indole + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + indolin-2-one + oxidized [NADPH--hemoprotein reductase]

RHEA:31919 indolin-2-one + O2 + reduced [NADPH--hemoprotein reductase] = 3-hydroxyindolin-2-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:31951 9beta-pimara-7,15-diene + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = 9beta-pimara-7,15-dien-19-oate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]

RHEA:31955 9beta-pimara-7,15-diene + O2 + reduced [NADPH--hemoprotein reductase] = 9beta-pimara-7,15-dien-19-ol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:31959 9beta-pimara-7,15-dien-19-ol + O2 + reduced [NADPH--hemoprotein reductase] = 9beta-pimara-7,15-dien-19-al + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:31963 9beta-pimara-7,15-dien-19-al + O2 + reduced [NADPH--hemoprotein reductase] = 9beta-pimara-7,15-dien-19-oate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:32447 all-trans-zeaxanthin + 2 H(+) + 2 NADH + 2 O2 = all-trans-violaxanthin + 2 H2O + 2 NAD(+)

RHEA:32455 (-)-vetispiradiene + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase] + solavetivone

RHEA:32471 demethylsuberosin + O2 + reduced [NADPH--hemoprotein reductase] = (7S)-marmesin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:33027 4 H(+) + 2 O2 + 4 reduced [2Fe-2S]-[ferredoxin] + spheroidene = 3 H2O + 4 oxidized [2Fe-2S]-[ferredoxin] + spheroiden-2-one

RHEA:33035 2-oxospirilloxanthin + 4 H(+) + 2 O2 + 4 reduced [2Fe-2S]-[ferredoxin] = 2,2'-dioxospirilloxanthin + 3 H2O + 4 oxidized [2Fe-2S]-[ferredoxin]

RHEA:33039 4 H(+) + 2 O2 + 4 reduced [2Fe-2S]-[ferredoxin] + spirilloxanthin = 2-oxospirilloxanthin + 3 H2O + 4 oxidized [2Fe-2S]-[ferredoxin]

RHEA:33295 L-hexahomomethionine + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = (E)-9-(methylsulfanyl)nonanal oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]

RHEA:33343 glycine + O2 = 2-iminoacetate + H2O2

RHEA:33671 2 [Fe(III)-cytochrome b5] + H2O + N-(2,3-dihydroxyhexacosanoyl)-(4S)-hydroxysphinganine = 2 [Fe(II)-cytochrome b5] + 2 H(+) + N-(2-hydroxyhexacosanyl)-(4R)-hydroxysphinganine + O2

RHEA:34003 5alpha-cholesta-7,24-dien-3beta-ol + H(+) + NADPH + O2 = cholesta-5,7,24-trien-3beta-ol + 2 H2O + NADP(+)

RHEA:34227 5-nitrosalicylate + O2 = 2-oxo-3-(5-oxofuran-2-ylidene)propanoate + H(+) + nitrite

RHEA:34231 5-nitrosalicylate + O2 = 4-nitro-6-oxohepta-2,4-dienedioate + H(+)

RHEA:34327 4-nitrophenol + H(+) + NADPH + O2 = 1,4-benzoquinone + H2O + NADP(+) + nitrite

RHEA:34399 9-cis-beta-carotene + O2 = 9-cis-10'-apo-beta-carotenal + beta-ionone

RHEA:34411 cannabigerolate + O2 = cannabidiolate + H2O2

RHEA:34499 1-deoxypentalenate + 2 H(+) + O2 + reduced 2[4Fe-4S]-[ferredoxin] = H2O + oxidized 2[4Fe-4S]-[ferredoxin] + pentalenate

RHEA:34575 2 H(+) + O2 + pentalenolactone F + 2 reduced [2Fe-2S]-[ferredoxin] = 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin] + pentalenolactone

RHEA:35107 3-nitrotyramine + H2O + O2 = 4-hydroxy-3-nitrophenylacetaldehyde + H2O2 + NH4(+)

RHEA:35499 11-oxo-beta-amyrin + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = glycyrrhetinate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]

RHEA:35503 11-oxo-beta-amyrin + O2 + reduced [NADPH--hemoprotein reductase] = 30-hydroxy-11-oxo-beta-amyrin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:35507 30-hydroxy-11-oxo-beta-amyrin + O2 + reduced [NADPH--hemoprotein reductase] = glycyrrhetaldehyde + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:35511 glycyrrhetaldehyde + O2 + reduced [NADPH--hemoprotein reductase] = glycyrrhetinate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:35547 cyclo(L-tyrosyl-L-tyrosyl) + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = 2 H2O + mycoclysin + 2 oxidized [2Fe-2S]-[ferredoxin]

RHEA:35555 cyclo(L-leucyl-L-leucyl) + 4 H(+) + 3 O2 + 6 reduced [2Fe-2S]-[ferredoxin] = 4 H2O + 6 oxidized [2Fe-2S]-[ferredoxin] + pulcherriminic acid

RHEA:35743 H(+) + NADPH + O2 + versicolorin B = 2 H2O + NADP(+) + versicolorin A

RHEA:36603 2-oxoglutarate + L-enduracididine + O2 = (3S)-3-hydroxy-L-enduracididine + CO2 + succinate

RHEA:36607 2-oxoglutarate + L-arginine + O2 = (2S,3S)-hydroxyarginine + CO2 + succinate

RHEA:36867 (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + AH2 + O2 = (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + A + 2 H2O

RHEA:36883 (8Z,11Z,14Z)-eicosatrienoyl-CoA + AH2 + O2 = (8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA + A + 2 H2O

RHEA:37583 D-lysine + H2O + O2 = 6-amino-2-oxohexanoate + H2O2 + NH4(+)

RHEA:37599 (9Z,12Z)-hexadecadienoyl-CoA + AH2 + O2 = (9Z,12Z,15Z)-hexadecatrienoyl-CoA + A + 2 H2O

RHEA:37835 aklavinone + H(+) + NADPH + O2 = epsilon-rhodomycinone + H2O + NADP(+)

RHEA:37971 H(+) + NADPH + O2 + octadecanoyl-CoA = (9Z)-octadecenoyl-CoA + 2 H2O + NADP(+)

RHEA:38179 O2 + reduced [NADPH--hemoprotein reductase] + testosterone = 19-hydroxytestosterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:38183 19-hydroxytestosterone + O2 + reduced [NADPH--hemoprotein reductase] = 19-oxotestosterone + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:38187 19-oxotestosterone + O2 + reduced [NADPH--hemoprotein reductase] = 17beta-estradiol + formate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:38579 dammarenediol-II + O2 + reduced [NADPH--hemoprotein reductase] = (20S)-protopanaxadiol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:39043 22-oxodocosanoate + O2 + reduced [NADPH--hemoprotein reductase] = docosanedioate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:39047 26-oxohexacosanoate + O2 + reduced [NADPH--hemoprotein reductase] = 2 H(+) + H2O + hexacosanedioate + oxidized [NADPH--hemoprotein reductase]

RHEA:39715 (9Z,12Z,15Z,18Z)-tetracosatetraenoyl-CoA + AH2 + O2 = (6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA + A + 2 H2O

RHEA:39719 O2 + reduced [NADPH--hemoprotein reductase] + tetracosanoate = H(+) + H2O + omega-hydroxytetracosanoate + oxidized [NADPH--hemoprotein reductase]

RHEA:39731 3-hydroxyhexadecanoate + O2 + reduced [NADPH--hemoprotein reductase] = 3,16-dihydroxyhexadecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:39735 3-hydroxyoctadecanoate + O2 + reduced [NADPH--hemoprotein reductase] = 3,18-dihydroxyoctadecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:39739 3-hydroxydodecanoate + H(+) + NADPH + O2 = 3,12-dihydroxydodecanoate + H2O + NADP(+)

RHEA:39767 20-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] = 20-oxo-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:39771 20-oxo-(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] = (5Z,8Z,11Z,14Z)-eicosatetraenedioate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:39775 (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + O2 + reduced [NADPH--hemoprotein reductase] = 17,18-epoxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:39815 2 [Fe(II)-cytochrome b5] + 2 H(+) + O2 + octadecanoate = 2-hydroxyoctadecanoate + 2 [Fe(III)-cytochrome b5] + H2O

RHEA:39819 2 [Fe(II)-cytochrome b5] + docosanoate + 2 H(+) + O2 = 2-hydroxydocosanoate + 2 [Fe(III)-cytochrome b5] + H2O

RHEA:39823 2 [Fe(II)-cytochrome b5] + eicosanoate + 2 H(+) + O2 = 2-hydroxyeicosanoate + 2 [Fe(III)-cytochrome b5] + H2O

RHEA:40083 hexacosanoate + O2 + reduced [NADPH--hemoprotein reductase] = 26-hydroxyhexacosanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:40127 an omega-oxo fatty acid + O2 + reduced [NADPH--hemoprotein reductase] = a dicarboxylate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:40215 FADH2 + O2 = FAD + H(+) + H2O2

RHEA:40315 glutaryl-CoA + O2 = (E)-glutaconyl-CoA + H2O2

RHEA:40319 O2 + tetracosanoyl-CoA = (2E)-tetracosenoyl-CoA + H2O2

RHEA:40495 N-[omega-(9Z,12Z)-octadecadienoyloxy]acyl-beta-D-glucosyl-(1<->1)-octadecasphing-4E-enine + O2 = N-[omega-(9R)-hydroperoxy-(10E,12Z)-octadecadienoyloxy]acyl-beta-D-glucosyl-(1<->1)-octadecasphing-4E-enine

RHEA:40559 dTDP-beta-L-evernosamine + NADPH + O2 = dTDP-N-hydroxy-beta-L-evernosamine + H2O + NADP(+)

RHEA:40567 AH2 + dTDP-2,3,6-trideoxy-3-C-methyl-4-O-methyl-3-nitroso-beta-L-arabino-hexopyranose + O2 = A + dTDP-beta-L-evernitrose + H2O

RHEA:41227 (S)-4-hydroxymandelate + O2 = 4-hydroxyphenylglyoxylate + H2O2

RHEA:41239 N-acyl (9Z,12Z)-octadecadienoate octadecasphin-4E-enine + O2 = N-acyl (9R)-hydroperoxy-(10E,12Z)-octadecadienoate octadecasphing-4E-enine

RHEA:41311 1-O-methyl (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = 1-O-methyl (5Z,8Z,10E,12R,14Z)-hydroperoxyiecosatetraenoate

RHEA:41315 1-O-methyl (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = (5Z,8Z,10E,12S,14Z)-hydroperoxyeicosatetraenoate methyl ester

RHEA:41324 (5Z,8Z,11Z)-eicosatrienoate + O2 = (5Z,8Z,10E,12S)-hydroperoxyeicosatrienoate

RHEA:41420 2 3-amino-4-hydroxybenzoate + H(+) + N-acetyl-L-cysteine + 2 O2 = CO2 + grixazone B + 4 H2O

RHEA:41424 2 3-amino-4-hydroxybenzaldehyde + N-acetyl-L-cysteine + 2 O2 = formate + grixazone A + H(+) + 3 H2O

RHEA:41516 O2 + phylloquinone + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + omega-hydroxyphylloquinone + oxidized [NADPH--hemoprotein reductase]

RHEA:41520 menaquinone-4 + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + omega-hydroxymenaquinone-4 + oxidized [NADPH--hemoprotein reductase]

RHEA:41560 (3S)-3-amino-3-(3-chloro-4-hydroxyphenyl)propanoyl-[SgcC2 peptidyl-carrier protein] + FADH2 + O2 = (3S)-3-amino-3-(3-chloro-4,5-dihydroxyphenyl)propanoyl-[SgcC2 peptidyl-carrier protein] + FAD + H(+) + H2O

RHEA:41756 1-O-methyl (9Z,12Z)-octadecadienoate + O2 = 1-O-methyl (9Z,11E,13S)-hydroperoxyoctadecadienoate

RHEA:42032 2 2-oxoglutarate + N(6),N(6)-dimethyl-L-lysine(36)-[histone H3] + 2 O2 = 2 CO2 + 2 formaldehyde + L-lysine(36)-[histone H3] + 2 succinate

RHEA:42088 all-trans-retinal + O2 + reduced [NADPH--hemoprotein reductase] = all-trans-retinoate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:42092 all-trans-retinol + O2 + reduced [NADPH--hemoprotein reductase] = all-trans-retinal + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:42280 (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = (5Z,8Z,11R,12E,14Z)-11-hydroperoxyeicosatetraenoate

RHEA:42284 (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = (15R)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate

RHEA:42476 2,2',3-trihydroxydiphenyl ether + H(+) + O2 = 2-hydroxy-6-(2-hydroxyphenoxy)-6-oxo-cis,cis-hexa-2,4-dienoate

RHEA:42568 2,3-dihydroxy-p-cumate + O2 = 3-carboxy-2-hydroxy-7-methyl-6-oxo-(2Z,4Z)-octadienoate + H(+)

RHEA:42680 2 hercynine + 2 L-selenocysteine + O2 = 2 H2O + 2 hercynylselenocysteine

RHEA:43504 5-hydroxymethylfurfural + O2 = 2,5-diformylfuran + H2O2

RHEA:43512 2-(dihydroxymethyl)-5-formylfuran + O2 = 2-carboxy-5-formylfuran + H(+) + H2O2

RHEA:43520 2-carboxy-5-(dihydroxymethyl)furan + O2 = 2,5-dicarboxyfuran + H(+) + H2O2

RHEA:43724 (2E,6E)-farnesoate + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + juvenile hormone III carboxylate + oxidized [NADPH--hemoprotein reductase]

RHEA:43840 26-hydroxycholesterol + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = (3beta)-hydroxy-cholest-5-en-26-al + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]

RHEA:44548 (omega-1)-ethyl fatty acid + O2 + reduced [NADPH--hemoprotein reductase] = (omega-1)-hydroxy fatty acid + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:45056 deoxynogalonate + O2 = H(+) + H2O + nogalonate

RHEA:45072 (9Z)-octadecenoyl-CoA + O2 + reduced [NADPH--hemoprotein reductase] = (9Z)-18-hydroxyoctadecenoyl-CoA + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:45084 dodecanoate + O2 + reduced [NADPH--hemoprotein reductase] = 7-hydroxydodecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:45108 (+)-alpha-tocopherol + O2 + reduced [NADPH--hemoprotein reductase] = 13-hydroxy-alpha-tocopherol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:45464 2 [Fe(II)-cytochrome b5] + eicosanoyl-CoA + 2 H(+) + O2 = (5Z)-eicosenoyl-CoA + 2 [Fe(III)-cytochrome b5] + 2 H2O

RHEA:45792 2-oxoglutarate + [ribosomal protein S23]-L-proline + O2 = [ribosomal protein S23]-trans-3-hydroxy-L-proline + CO2 + succinate

RHEA:45972 3-oxochol-4-en-22-oate + H(+) + NADH + O2 = 9alpha-hydroxy-3-oxochol-4-en-22-oate + H2O + NAD(+)

RHEA:45976 3-oxochola-1,4-dien-22-oate + H(+) + NADH + O2 = 9alpha-hydroxy-3-oxochola-1,4-dien-22-oate + H2O + NAD(+)

RHEA:45980 3-oxochol-4-en-22-oyl-CoA + H(+) + NADH + O2 = 9alpha-hydroxy-3-oxochol-4-en-22-oyl-CoA + H2O + NAD(+)

RHEA:45984 3-oxochola-1,4-dien-22-oyl-CoA + H(+) + NADH + O2 = 9alpha-hydroxy-3-oxochola-1,4-dien-22-oyl-CoA + H2O + NAD(+)

RHEA:45988 3,17-dihydroxy-9,10-seconandrost-1,3,5(10)-triene-9-one + FMNH2 + O2 = 3,4,17-trihydroxy-9,10-seconandrost-1,3,5(10)-triene-9-one + FMN + H(+) + H2O

RHEA:46136 aminopyrrolnitrin + H(+) + NADPH + 2 O2 = 2 H2O + NADP(+) + pyrrolnitrin

RHEA:46232 (9Z,12Z)-hexadecadienoyl-CoA + 2 [Fe(II)-cytochrome b5] + 2 H(+) + O2 = (9Z,12Z,15Z)-hexadecatrienoyl-CoA + 2 [Fe(III)-cytochrome b5] + 2 H2O

RHEA:46392 4beta-hydroxycholesterol + O2 + reduced [NADPH--hemoprotein reductase] = 4beta,24S-dihydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:46428 4beta-hydroxycholesterol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = (25R)-4beta,26-dihydroxycholesterol + H2O + 2 oxidized [adrenodoxin]

RHEA:46432 (25R)-4beta,26-dihydroxycholesterol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = (25R)-3beta,4beta-dihydroxycholest-5-en-26-al + 2 H2O + 2 oxidized [adrenodoxin]

RHEA:46436 (25R)-3beta,4beta-dihydroxycholest-5-en-26-al + H(+) + O2 + 2 reduced [adrenodoxin] = (25R)-3beta,4beta-dihydroxycholest-5-en-26-oate + H2O + 2 oxidized [adrenodoxin]

RHEA:46472 4alpha-methyl-5alpha-cholesta-8,24-dien-3beta-ol + H(+) + NADPH + O2 = 4alpha-hydroxymethyl-5alpha-cholesta-8,24-dien-3beta-ol + H2O + NADP(+)

RHEA:46476 4alpha-hydroxymethyl-5alpha-cholesta-8,24-dien-3beta-ol + H(+) + NADPH + O2 = 4alpha-formyl-5alpha-cholesta-8,24-dien-3beta-ol + 2 H2O + NADP(+)

RHEA:46480 4alpha-formyl-5alpha-cholesta-8,24-dien-3beta-ol + NADPH + O2 = 4alpha-carboxy-5alpha-cholesta-8,24-dien-3beta-ol + H2O + NADP(+)

RHEA:46536 (6Z,9Z,12Z)-octadecatrienoyl-containing glycerolipid + 2 [Fe(II)-cytochrome b5] + 2 H(+) + O2 = 2 [Fe(III)-cytochrome b5] + a (9Z,12Z)-octadeca-9,12-dien-6-ynoyl-containing glycerolipid + 2 H2O

RHEA:46540 (6Z,9Z,12Z,15Z)-octadecatetraenoyl-containing glycerolipid + 2 [Fe(II)-cytochrome b5] + 2 H(+) + O2 = 2 [Fe(III)-cytochrome b5] + a (9Z,12Z,15Z)-octadeca-9,12,15-trien-6-ynoyl-containing glycerolipid + 2 H2O

RHEA:46576 (24R)-ethylcholest-5-en-3beta-ol + H(+) + NADPH + O2 = 2 H2O + NADP(+) + stigmasterol

RHEA:46596 NADPH + O2 + rifampicin = 2'-N-hydroxyrifampicin + H2O + NADP(+)

RHEA:46756 a 1-acyl-2-hexadecanoyl-glycerolipid + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = a 1-acyl-2-[(7Z)-hexadecenoyl]-glycerolipid + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]

RHEA:46784 a 1-[(9Z,12Z)-octadecdienoyl]-2-acyl-glycerolipid + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = a 1-[(9Z,12Z,15Z)-octadectrienoyl]-2-acyl-glycerolipid + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]

RHEA:46788 a 1-[(6Z,9Z,12Z)-octadectrienoyl]-2-acyl-glycerolipid + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = a 1-[(6Z,9Z,12Z,15Z)-octadectetraenoyl]-2-acyl-glycerolipid + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]

RHEA:47056 4alpha-methyl-5alpha-cholesta-8,24-dien-3beta-ol + 2 H(+) + 3 NADPH + 3 O2 = 4alpha-carboxy-5alpha-cholesta-8,24-dien-3beta-ol + 4 H2O + 3 NADP(+)

RHEA:47060 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + H(+) + NADPH + O2 = 4alpha-hydroxymethyl-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol + H2O + NADP(+)

RHEA:47064 4alpha-hydroxymethyl-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol + H(+) + NADPH + O2 = 4alpha-formyl-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol + 2 H2O + NADP(+)

RHEA:47068 4alpha-formyl-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol + NADPH + O2 = 4alpha-carboxyl-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol + H2O + NADP(+)

RHEA:47216 17beta-estradiol + O2 + reduced [NADPH--hemoprotein reductase] = 6beta-hydroxyestradiol-17beta + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:47276 17beta-estradiol + O2 + reduced [NADPH--hemoprotein reductase] = 15alpha-hydroxy-17beta-estradiol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:47284 17beta-estradiol + O2 + reduced [NADPH--hemoprotein reductase] = 6alpha-hydroxy-17beta-estradiol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:47288 17beta-estradiol + O2 + reduced [NADPH--hemoprotein reductase] = 7alpha-hydroxy-17beta-estradiol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:47292 estrone + O2 + reduced [NADPH--hemoprotein reductase] = 4-hydroxyestrone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:47308 estrone + O2 + reduced [NADPH--hemoprotein reductase] = 6alpha-hydroxyestrone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:47312 estrone + O2 + reduced [NADPH--hemoprotein reductase] = 15alpha-hydroxyestrone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:47336 17beta-estradiol + O2 + reduced [NADPH--hemoprotein reductase] = 16beta,17beta-estriol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:47340 estrone + O2 + reduced [NADPH--hemoprotein reductase] = 6beta-hydroxyestrone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:48008 2-hydroxybenzoyl-CoA + H(+) + NADH + O2 = 2,5-dihydroxybenzoyl-CoA + H2O + NAD(+)

RHEA:48568 3-chlorocatechol + O2 = (2E,4Z)-2-chloromuconate + 2 H(+)

RHEA:48736 (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] = 18(R)-HETE + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:48776 O2 + prostaglandin H2 + reduced [NADPH--hemoprotein reductase] = 19-hydroxyprostaglandin H2 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:48796 O2 + prostaglandin H1 + reduced [NADPH--hemoprotein reductase] = 19-hydroxyprostaglandin H1 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:48936 2-oxoglutarate + [Skp1 protein]-L-proline + O2 = [Skp1 protein]-trans-4-hydroxy-L-proline + CO2 + succinate

RHEA:48988 NADH + O2 + rifampicin = 2'-N-hydroxyrifampicin + H2O + NAD(+)

RHEA:48996 3-methylcatechol + O2 = 2-hydroxy-6-oxo-2,4-heptadienoate + H(+)

RHEA:49048 25-hydroxyvitamin D2 + 2 H(+) + O2 + 2 reduced [adrenodoxin] = 1alpha,25-dihydroxyvitamin D2 + H2O + 2 oxidized [adrenodoxin]

RHEA:49068 25-hydroxy-24-oxocalciol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = (1S)-1,25-dihydroxy-24-oxocalciol + H2O + 2 oxidized [adrenodoxin]

RHEA:49084 (-)-matairesinol + O2 + reduced [NADPH--hemoprotein reductase] = (-)-pluviatolide + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:49160 1,4-cineole + H(+) + NADPH + O2 = 2-exo-hydroxy-1,4-cineole + H2O + NADP(+)

RHEA:49212 20S-hydroxycholecalciferol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = 20S,25-dihydroxycholecalciferol + H2O + 2 oxidized [adrenodoxin]

RHEA:49328 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] + spheroidene = 2-hydroxyspheroidene + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]

RHEA:49332 2-hydroxyspheroidene + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = 2,2-dihydroxyspheroidene + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]

RHEA:49340 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] + spirilloxanthin = 2-hydroxyspirilloxanthin + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]

RHEA:49344 2-hydroxyspirilloxanthin + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = 2,2-dihydroxyspirilloxanthin + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]

RHEA:49352 2-oxospirilloxanthin + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = 2'-hydroxy-2-oxospirilloxanthin + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]

RHEA:49356 2'-hydroxy-2-oxospirilloxanthin + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = 2',2'-dihydroxy-2-oxospirilloxanthin + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]

RHEA:49392 20S,23-dihydroxycholecalciferol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = 20S,23,24-trihydroxycholecalciferol + H2O + 2 oxidized [adrenodoxin]

RHEA:49396 20S,23-dihydroxycholecalciferol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = 20S,23,25-trihydroxycholecalciferol + H2O + 2 oxidized [adrenodoxin]

RHEA:49524 2-oxoglutarate + an N(6)-methyl-2'-deoxyadenosine in DNA + O2 = a 2'-deoxyadenosine in DNA + CO2 + formaldehyde + succinate

RHEA:49936 (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] = 5,6-epoxy-(8Z,11Z,14Z)-eicosatrienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:50012 H(+) + NADPH + O2 + tert-butanol = 2-methylpropane-1,2-diol + H2O + NADP(+)

RHEA:50076 (5Z,8Z,11Z)-eicosatrienoate + O2 + reduced [NADPH--hemoprotein reductase] = 19-hydroxy-(5Z,8Z,11Z)-eicosatrienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:50096 O2 + reduced [NADPH--hemoprotein reductase] + tetradecanoate = 13-hydroxytetradecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:50164 (5Z,8Z,11Z)-eicosatrienoate + O2 + reduced [NADPH--hemoprotein reductase] = 20-hydroxy-(5Z,8Z,11Z)-eicosatrienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:50236 O2 + pregnenolone + reduced [NADPH--hemoprotein reductase] = 17alpha-hydroxypregnenolone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:50304 O2 + progesterone + reduced [NADPH--hemoprotein reductase] = 21-hydroxyprogesterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:50308 17alpha-hydroxyprogesterone + O2 + reduced [NADPH--hemoprotein reductase] = 11-deoxycortisol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:50320 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + O2 + reduced [NADPH--hemoprotein reductase] = 1-[(9R,10S)-epoxy-octadecanoyl]-sn-glycero-3-phosphocholine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:50324 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + O2 + reduced [NADPH--hemoprotein reductase] = 1-[(9S,10R)-epoxy-octadecanoyl]-sn-glycero-3-phosphocholine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:50328 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + O2 + reduced [NADPH--hemoprotein reductase] = 1-[8-hydroxy-(9Z)-octadecenoyl]-sn-glycero-3-phosphocholine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:50332 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + O2 + reduced [NADPH--hemoprotein reductase] = 1-[11-hydroxy-(9Z)-octadecenoyl]-sn-glycero-3-phosphocholine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:50336 O2 + reduced [NADPH--hemoprotein reductase] + triacontanoate = H(+) + H2O + omega-hydroxy-triacontanoate + oxidized [NADPH--hemoprotein reductase]

RHEA:50824 (4Z,7Z,10Z,13Z,16Z)-docosapentaenoate + O2 = 14-hydroperoxy-(4Z,7Z,10Z,12E,16Z)-docosapentaenoate

RHEA:50828 (4Z,7Z,10Z,13Z,16Z)-docosapentaenoate + O2 = (17S)-hydroperoxy-(4Z,7Z,10Z,13Z,15E)-docosapentaenoate

RHEA:50832 (7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + O2 = 17-hydroperoxy-(7Z,10Z,13Z,15E,19Z)-docosapentaenoate

RHEA:50836 (7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + O2 = 14-hydroperoxy-(7Z,10Z,12E,16Z,19Z)-docosapentaenoate

RHEA:50840 (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 = (17S)-hydroperoxy-(4Z,7Z,10Z,13Z,15E,19Z)-docosahexaenoate

RHEA:51136 (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + 2 O2 = (10,17S)-dihydroperoxy-(4Z,7Z,11Z,13Z,15E,19Z)-docosahexaenoate

RHEA:51140 (4Z,7Z,10Z,13Z,16Z)-docosapentaenoate + 2 O2 = (10,17S)-dihydroperoxy-(4Z,7Z,11Z,13Z,15E)-docosapentaenoate

RHEA:51144 (7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + 2 O2 = (10,17)-dihydroperoxy-(7Z,11Z,13Z,15E,19Z)-docosapentaenoate

RHEA:51448 chenodeoxycholate + O2 + reduced [NADPH--hemoprotein reductase] = alpha-muricholate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:51452 O2 + reduced [NADPH--hemoprotein reductase] + ursodeoxycholate = beta-muricholate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:51484 (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] = 12-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:51492 all-trans-retinoate + O2 + reduced [NADPH--hemoprotein reductase] = all-trans-(4S)-hydroxyretinoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:51540 (S)-reticuline + O2 + reduced [NADPH--hemoprotein reductase] = (S)-corytuberine + 2 H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:51632 all-trans-(4S)-hydroxyretinoate + O2 + reduced [NADPH--hemoprotein reductase] = all-trans-(4S,16)-dihydroxyretinoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:51880 3,4,6-trichlorocatechol + O2 = (2Z,4E)-2,3,5-trichloromuconate + H(+)

RHEA:52156 (E)-phenylacetaldehyde oxime + O2 + reduced [NADPH--hemoprotein reductase] = (R)-mandelonitrile + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:52204 butachlor + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = butyl formate + H2O + N-(2,6-diethylphenyl)-2-chloroacetamide + 2 oxidized [2Fe-2S]-[ferredoxin]

RHEA:52208 alachlor + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = H2O + methyl formate + N-(2,6-diethylphenyl)-2-chloroacetamide + 2 oxidized [2Fe-2S]-[ferredoxin]

RHEA:52212 acetochlor + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = ethyl formate + H2O + N-(2-ethyl-6-methylphenyl)-2-chloroacetamide + 2 oxidized [2Fe-2S]-[ferredoxin]

RHEA:52284 (9Z,12Z)-octadecadienoate + O2 + reduced [NADPH--hemoprotein reductase] = 11-hydroxy-(9Z,12Z)-octadecadienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:52288 (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] = 7-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:52292 (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] = 13-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:52300 (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] = (12R)-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:52480 16-methoxytabersonine + O2 + reduced [NADPH--hemoprotein reductase] = (3R)-1,2-didehydro-3-hydroxy-16-methoxy-2,3-dihydrotabersonine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:52488 O2 + prostaglandin E2 + reduced [NADPH--hemoprotein reductase] = 20-hydroxy prostaglandin E2 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:52492 (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] = (11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:52496 (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] = (15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:52500 (9Z,12Z)-octadecadienoate + O2 + reduced [NADPH--hemoprotein reductase] = (13R)-hydroxy-(9Z,11E)-octadecadienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:52504 (9Z,12Z)-octadecadienoate + O2 + reduced [NADPH--hemoprotein reductase] = 9(R)-hydroxy-(10E,12Z)-octadecadienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:52508 (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] = 13(S)-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:52972 a C2-C8-saturated long-chain fatty acyl-[ACP] + O2 + reduced [flavodoxin] = a (7S)-7-hydroxy-C2-C8-saturated long-chain fatty acyl-[ACP] + H(+) + H2O + oxidized [flavodoxin]

RHEA:52976 a (7S)-7-hydroxy-C2-C8-saturated long-chain fatty acyl-[ACP] + O2 + reduced [flavodoxin] = a (7R,8R)-7,8-dihydroxy-C2-C8-saturated long-chain fatty acyl-[ACP] + H(+) + H2O + oxidized [flavodoxin]

RHEA:52980 a (7R,8R)-7,8-dihydroxy-C2-C8-saturated long-chain fatty acyl-[ACP] + O2 + reduced [flavodoxin] = 7-oxoheptanoyl-[ACP] + a fatty aldehyde + H(+) + 2 H2O + oxidized [flavodoxin]

RHEA:53156 N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + N-(5,6-epoxy-8Z,11Z,14Z-eicosatrienoyl)-ethanolamine + oxidized [NADPH--hemoprotein reductase]

RHEA:53196 O2 + reduced [NADPH--hemoprotein reductase] + testosterone = 16alpha,17beta-dihydroxyandrost-4-en-3-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:53216 17alpha-hydroxyprogesterone + O2 + reduced [NADPH--hemoprotein reductase] = 16alpha,17alpha-dihydroxyprogesterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:53220 16alpha,17alpha-dihydroxyprogesterone + O2 + reduced [NADPH--hemoprotein reductase] = 6beta,16alpha,17alpha-trihydroxyprogesterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:53224 16alpha,17alpha-dihydroxypregnenolone + O2 + reduced [NADPH--hemoprotein reductase] = 3beta,16alpha-dihydroxy-androst-5-en-17-one + acetate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:53228 androst-4-ene-3,17-dione + O2 + reduced [NADPH--hemoprotein reductase] = 16alpha-hydroxyandrost-4-ene-3,17-dione + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:53248 cholesta-5,7-dien-3beta-ol + O2 + reduced [NADPH--hemoprotein reductase] = 3beta-hydroxycholest-5-en-7-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:53252 5alpha-cholest-7-en-3beta-ol + O2 + reduced [NADPH--hemoprotein reductase] = 5alpha-cholestan-7-oxo-3beta-ol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:53256 5alpha-cholest-7-en-3beta-ol + O2 + reduced [NADPH--hemoprotein reductase] = 7alpha,8alpha-epoxy-5alpha-cholestan-3beta-ol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:53276 17beta-hydroxy-3,19-dioxo-5alpha-androstanone + O2 + reduced [NADPH--hemoprotein reductase] = 17beta-hydroxy-3-oxo-19-nor-5alpha-androst-1-ene + formate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:53308 (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] = 16(R)-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:53312 (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] = 16(S)-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:53392 2-phenylacetate + O2 + reduced [NADPH--hemoprotein reductase] = (2-hydroxyphenyl)acetate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:53444 O2 + reduced [NADPH--hemoprotein reductase] + testosterone = 11beta,17beta-dihydroxyandrost-4-ene-3-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:53552 (9S,10R)-epoxy-octadecanoate + O2 + reduced [NADPH--hemoprotein reductase] = 18-hydroxy-(9S,10R)-epoxy-octadecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:53556 (9R,10S)-epoxy-octadecanoate + O2 + reduced [NADPH--hemoprotein reductase] = 18-hydroxy-(9R,10S)-epoxy-octadecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:53560 9,10-epoxyoctadecanoate + O2 + reduced [NADPH--hemoprotein reductase] = 18-hydroxy-9,10-epoxy-octadecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:53564 9,10-epoxy-(12Z)-octadecenoate + O2 + reduced [NADPH--hemoprotein reductase] = 18-hydroxy-9,10-epoxy-(12Z)-octadecenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:53568 12,13-epoxy-(9Z)-octadecenoate + O2 + reduced [NADPH--hemoprotein reductase] = 18-hydroxy-12,13-epoxy-(9Z)-octadecenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:53572 8,9-epoxy-(5Z,11Z,14Z)-eicosatrienoate + O2 + reduced [NADPH--hemoprotein reductase] = 20-hydroxy-8,9-epoxy-(5Z,11Z,14Z)-eicosatrienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:53576 11,12-epoxy-(5Z,8Z,14Z)-eicosatrienoate + O2 + reduced [NADPH--hemoprotein reductase] = 20-hydroxy-11,12-epoxy-(5Z,8Z,14Z)-eicosatrienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:53580 14,15-epoxy-(5Z,8Z,11Z)-eicosatrienoate + O2 + reduced [NADPH--hemoprotein reductase] = 20-hydroxy-14,15-epoxy-(5Z,8Z,11Z)-eicosatrienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:53808 cholestanol + O2 + reduced [NADPH--hemoprotein reductase] = (24S)-hydroxycholestanol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:53812 cholestanol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = (25R)-26-hydroxycholestanol + H2O + 2 oxidized [adrenodoxin]

RHEA:53932 O2 + prostaglandin I2 + reduced [NADPH--hemoprotein reductase] = 19-hydroxy-prostaglandin I2 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:53936 O2 + reduced [NADPH--hemoprotein reductase] + thromboxane A2 = 19-hydroxy-thromboxane A2 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:53940 O2 + reduced [NADPH--hemoprotein reductase] + thromboxane A2 = 18-hydroxy-thromboxane A2 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:54156 2-oxoglutarate + [ribosomal protein uS12]-L-proline + O2 = [ribosomal protein uS12]-(3S)-3-hydroxy-L-proline + CO2 + succinate

RHEA:54160 2-oxoglutarate + [ribosomal protein uS12]-(3S)-3-hydroxy-L-proline + O2 = [ribosomal protein uS12]-(3S)-3,4-dihydroxy-L-proline + CO2 + succinate

RHEA:54280 2-oxoglutarate + L-aspartyl-[ankyrin-repeat domain protein] + O2 = (3S)-3-hydroxy-L-aspartyl-[ankyrin-repeat domain protein] + CO2 + succinate

RHEA:54740 9alpha,11alpha-methylene thromboxane A2 + O2 + reduced [NADPH--hemoprotein reductase] = 19-hydroxy-9alpha,11alpha-methylene thromboxane A2 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:54744 9alpha,11alpha-methylene thromboxane A2 + O2 + reduced [NADPH--hemoprotein reductase] = 18-hydroxy-9alpha,11alpha-methylene thromboxane A2 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:55024 O2 + reduced [NADPH--hemoprotein reductase] + tabersonine = (3R)-1,2-didehydro-3-hydroxy-2,3-dihydrotabersonine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:55440 beta-amyrin + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + maniladiol + oxidized [NADPH--hemoprotein reductase]

RHEA:55444 O2 + oleanolate + reduced [NADPH--hemoprotein reductase] = cochalate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:55456 ferruginol + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase] + sugiol

RHEA:55460 11-hydroxyferruginol + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = 11-hydroxysugiol + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]

RHEA:55464 11-hydroxysugiol + O2 + reduced [NADPH--hemoprotein reductase] = 11,20-dihydroxysugiol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:55468 11-hydroxyferruginol + O2 + reduced [NADPH--hemoprotein reductase] = 11,20-dihydroxyferruginol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:55504 (5S,9S,10S)-drim-7-en-11-ol + O2 + reduced [NADPH--hemoprotein reductase] = (5S,10S)-(9R)-7-drimene-11,12-diol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:55508 cucurbitadienol + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = 11-oxocucurbitadienol + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]

RHEA:55512 cucurbitadienol + O2 + reduced [NADPH--hemoprotein reductase] = 11-hydroxycucurbitadienol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:55516 11-hydroxycucurbitadienol + O2 + reduced [NADPH--hemoprotein reductase] = 11-oxocucurbitadienol + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:55524 H(+) + H2O + L-dopa + O2 = 3,4-dihydroxyphenylacetaldehyde + CO2 + H2O2 + NH4(+)

RHEA:56288 albendazole + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + hydroxyalbendazole + oxidized [NADPH--hemoprotein reductase]

RHEA:56292 fenbendazole + O2 + reduced [NADPH--hemoprotein reductase] = 4'-hydroxyfenbendazole + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:56348 4-hydroxybenzoate + 2 bromide + 5 H(+) + 2 NADPH + 2 O2 = 2,4-dibromophenol + CO2 + 4 H2O + 2 NADP(+)

RHEA:56352 4-hydroxybenzoate + bromide + 2 H(+) + NADPH + O2 = 3-bromo-4-hydroxybenzoate + 2 H2O + NADP(+)

RHEA:56356 3-bromo-4-hydroxybenzoate + bromide + 3 H(+) + NADPH + O2 = 2,4-dibromophenol + CO2 + 2 H2O + NADP(+)

RHEA:56368 3,4-dihydroxybenzoate + 2 bromide + 5 H(+) + 2 NADPH + 2 O2 = 3,5-dibromobenzene-1,2-diol + CO2 + 4 H2O + 2 NADP(+)

RHEA:56372 3,4-dihydroxybenzoate + bromide + 2 H(+) + NADPH + O2 = 3-bromo-4,5-dihydroxybenzoate + 2 H2O + NADP(+)

RHEA:56376 3-bromo-4,5-dihydroxybenzoate + bromide + 3 H(+) + NADPH + O2 = 3,5-dibromobenzene-1,2-diol + CO2 + 2 H2O + NADP(+)

RHEA:56484 3 O2 + oleanolate + 3 reduced [NADPH--hemoprotein reductase] = gypsogenate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]

RHEA:56488 O2 + oleanolate + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + hederagenin + oxidized [NADPH--hemoprotein reductase]

RHEA:56492 hederagenin + O2 + reduced [NADPH--hemoprotein reductase] = gypsogenin + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:56496 gypsogenin + O2 + reduced [NADPH--hemoprotein reductase] = gypsogenate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:56700 (2S)-3-(1H-indol-3-yl)-2-isocyanopropanoate + 2-oxoglutarate + H(+) + O2 = 3-[(Z)-2-isocyanoethenyl]-1H-indole + 2 CO2 + H2O + succinate

RHEA:56708 beta-amyrin + O2 + reduced [NADPH--hemoprotein reductase] = 16alpha-hydroxy-beta-amyrin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:56776 (+)-pinoresinol + O2 + reduced [NADPH--hemoprotein reductase] = (+)-piperitol + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:56780 (+)-piperitol + O2 + reduced [NADPH--hemoprotein reductase] = (+)-sesamin + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:56820 AH2 + cyclooctat-9-en-7-ol + O2 = A + cyclooctat-9-ene-5,7-diol + H2O

RHEA:56824 AH2 + cyclooctat-9-ene-5,7-diol + O2 = A + cyclooctatin + H2O

RHEA:57516 dolabradiene + O2 + reduced [NADPH--hemoprotein reductase] = 15,16-epoxydolabrene + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:57520 15,16-epoxydolabrene + O2 + reduced [NADPH--hemoprotein reductase] = 3beta-hydroxy-15,16-epoxydolabrene + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:57660 (+)-valencene + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = (+)-nootkatone + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]

RHEA:57664 (+)-valencene + O2 + reduced [NADPH--hemoprotein reductase] = alpha-nootkatol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:57668 alpha-nootkatol + O2 + reduced [NADPH--hemoprotein reductase] = (+)-nootkatone + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:57672 (+)-5-epi-aristolochene + O2 + reduced [NADPH--hemoprotein reductase] = 2beta-hydroxy-5-epi-aristolochene + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:57676 4-epi-eremophilene + O2 + reduced [NADPH--hemoprotein reductase] = 4-epi-eremophilene-2beta-ol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:57864 indole-3-carbonyl nitrile + O2 + reduced [NADPH--hemoprotein reductase] = 4-hydroxy-indole-3-carbonyl nitrile + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:57968 germacra-1(10),4,11(13)-trien-12-oate + O2 + reduced [NADPH--hemoprotein reductase] = 8-epi-inunolide + 2 H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:57972 8beta-hydroxygermacra-1(10),4,11(13)-trien-12-oate + O2 + reduced [NADPH--hemoprotein reductase] = eupatolide + 2 H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:58016 8beta-hydroxygermacra-1(10),4,11(13)-trien-12-oate + O2 + reduced [NADPH--hemoprotein reductase] = 6alpha,8beta-hydroxygermacra-1(10),4,11(13)-trien-12-oate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:58032 germacra-1(10),4,11(13)-trien-12-oate + O2 + reduced [NADPH--hemoprotein reductase] = 8alpha-hydroxygermacra-1(10),4,11(13)-trien-12-oate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:10012 (R)-6-hydroxynicotine + H2O + O2 = 6-hydroxypseudooxynicotine + H2O2

RHEA:10104 2-oxoglutarate + gibberellin A20 + O2 = CO2 + gibberellin A1 + succinate

RHEA:10312 H(+) + NADH + O2 + terephthalate = (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate + NAD(+)

RHEA:10692 6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate + 3 O2 = H(+) + 2 H2O + 2 H2O2 + pyrroloquinoline quinone

RHEA:11152 5-pyridoxate + NADPH + O2 = 2-(acetamidomethylene)-3-(hydroxymethyl)succinate + NADP(+)

RHEA:11732 O2 + reduced [NADPH--hemoprotein reductase] + sophoraflavanone B = H(+) + H2O + leachianone G + oxidized [NADPH--hemoprotein reductase]

RHEA:12204 dihydromonacolin L carboxylate + O2 + reduced [NADPH--hemoprotein reductase] = 3alpha-hydroxy-3,5-dihydromonacolin L carboxylate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:12877 acetylacetone + O2 = acetate + H(+) + methylglyoxal

RHEA:13021 4-hydroxy-3-methoxybenzoate + H(+) + NADH + O2 = 3,4-dihydroxybenzoate + formaldehyde + H2O + NAD(+)

RHEA:14361 H2O + O2 + S-prenyl-L-cysteine = 3-methyl-2-butenal + H2O2 + L-cysteine

RHEA:15005 2-oxoglutarate + gibberellin A1 + O2 = CO2 + gibberellin A8 + succinate

RHEA:15697 liquiritigenin + O2 + reduced [NADPH--hemoprotein reductase] = 2 H(+) + H2O + licodione + oxidized [NADPH--hemoprotein reductase]

RHEA:15717 daunorubicin + H(+) + NADPH + O2 = doxorubicin + H2O + NADP(+)

RHEA:16761 chlorohydroquinone + O2 = 5-chlorocarbonyl-4-hydroxy-penta-2,4-dienoate + H(+)

RHEA:17293 2 H(+) + NADH + O2 + precorrin-3A = H2O + NAD(+) + precorrin-3B

RHEA:17357 O2 + 2 R'C(R)SH = H2O2 + R'C(R)S-S(R)CR'

RHEA:18033 benzoate + O2 + reduced [NADPH--hemoprotein reductase] = 4-hydroxybenzoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:18057 O2 + Watasenia luciferin = CO2 + hnu + oxidized Watasenia luciferin

RHEA:18613 4-methoxybenzoate + AH2 + O2 = 4-hydroxybenzoate + A + formaldehyde + H2O

RHEA:18621 2-oxoglutarate + a (2S)-flavan-4-one + O2 = a (2R,3R)-dihydroflavonol + CO2 + succinate

RHEA:19901 L-tryptophan + O2 = alpha,beta-didehydrotryptophan + H2O2

RHEA:20361 4-hydroxy-3-all-trans-hexaprenylbenzoate + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = 3,4-dihydroxy-5-all-trans-hexaprenylbenzoate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]

RHEA:20417 coelenterazine + O2 = CO2 + coelenteramide + hnu

RHEA:20848 H(+) + O2 + phosphate + pyruvate = acetyl phosphate + CO2 + H2O2

RHEA:21076 2'-deoxyuridine + 2-oxoglutarate + O2 = CO2 + succinate + uridine

RHEA:21628 17alpha-hydroxyprogesterone + NADPH + O2 = acetate + androst-4-ene-3,17-dione + H2O + NADP(+)

RHEA:21632 2 catechol + O2 = 2 1,2-benzoquinone + 2 H2O

RHEA:21880 2 H(+) + O2 + oxalate = 2 CO2 + H2O2

RHEA:22204 3-hydroxyphenylacetate + H(+) + NADPH + O2 = H2O + homogentisate + NADP(+)

RHEA:22208 3-hydroxyphenylacetate + H(+) + NADH + O2 = H2O + homogentisate + NAD(+)

RHEA:22548 H2O + L-lysine + O2 = (S)-2-amino-6-oxohexanoate + H2O2 + NH4(+)

RHEA:22620 H(+) + L-tryptophan + O2 = 3-indoleglycolaldehyde + CO2 + NH4(+)

RHEA:22756 a long-chain primary fatty alcohol + O2 = a long-chain fatty aldehyde + H2O2

RHEA:22916 4'-hydroxyacetophenone + H(+) + NADPH + O2 = 4-hydroxyphenyl acetate + H2O + NADP(+)

RHEA:22952 O2 + octanedioyl-CoA = (2E)-octenedioyl-CoA + H2O2

RHEA:23640 1-aminocyclopropane-1-carboxylate + L-ascorbate + O2 = CO2 + ethene + 2 H2O + hydrogen cyanide + L-dehydroascorbate

RHEA:23696 myo-inositol + O2 = D-glucuronate + H(+) + H2O

RHEA:23852 catechol + O2 = cis,cis-muconate + 2 H(+)

RHEA:24220 beta-myrcene + O2 + reduced [NADPH--hemoprotein reductase] = (4R)-ipsdienol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:24992 L-phenylalanine + O2 + reduced [NADPH--hemoprotein reductase] = 2 H(+) + H2O + N-hydroxy-L-phenylalanine + oxidized [NADPH--hemoprotein reductase]

RHEA:24996 N-hydroxy-L-phenylalanine + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + N,N-dihydroxy-L-phenylalanine + oxidized [NADPH--hemoprotein reductase]

RHEA:25395 (9Z,12Z)-octadecadienoate + O2 = (8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoate

RHEA:25658 (R)-pulegone + O2 + reduced [NADPH--hemoprotein reductase] = (R)-menthofuran + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:26077 methanesulfonate + NADH + O2 = formaldehyde + H2O + NAD(+) + sulfite

RHEA:26217 abieta-7,13-diene + O2 + reduced [NADPH--hemoprotein reductase] = abieta-7,13-dien-18-ol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:26397 all-trans-zeaxanthin + 2 O2 = 2 3beta-hydroxy-beta-cyclocitral + crocetin dialdehyde

RHEA:26494 chloride + FADH2 + L-tryptophan + O2 = 7-chloro-L-tryptophan + FAD + 2 H2O

RHEA:27333 6-hydroxynicotinate + 2 H(+) + NADH + O2 = 2,5-dihydroxypyridine + CO2 + H2O + NAD(+)

RHEA:28422 (1E,2S)-2-methylbutanal oxime + O2 + reduced [NADPH--hemoprotein reductase] = 2-hydroxy-2-methylbutanenitrile + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:28927 3,4,5-trihydroxybenzoate + O2 = (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate + 2 H(+)

RHEA:30231 H2O + O2 + S-(2E,6E)-farnesyl-L-cysteine = (2E,6E)-farnesal + H2O2 + L-cysteine

RHEA:30243 4 L-ascorbate + O2 = 2 H2O + 4 monodehydro-L-ascorbate radical

RHEA:30251 2 a ubiquinol + n H(+)(in) + O2 = 2 a ubiquinone + n H(+)(out) + 2 H2O

RHEA:30351 H(+) + NADH + O2 + pyrrole-2-carboxylate = 5-hydroxypyrrole-2-carboxylate + H2O + NAD(+)

RHEA:30355 a quinol + methane + O2 = a quinone + H2O + methanol

RHEA:30395 (S)-2-hydroxypropylphosphonate + H(+) + NADH + O2 = (1R,2S)-epoxypropylphosphonate + 2 H2O + NAD(+)

RHEA:30591 H2O + O2 + tyramine = (4-hydroxyphenyl)acetaldehyde + H2O2 + NH4(+)

RHEA:31271 1-hydroxy-2-naphthoate + 2 H(+) + NADH + O2 = CO2 + H2O + NAD(+) + naphthalene-1,2-diol

RHEA:31523 2-oxoglutarate + 2 H(+) + O2 = 3 CO2 + ethene + H2O

RHEA:31531 2-oxoglutarate + L-arginine + O2 = CO2 + N(omega)-hydroxy-L-arginine + succinate

RHEA:31571 1-hydroxy-2-naphthoate + 2 H(+) + NADPH + O2 = CO2 + H2O + NADP(+) + naphthalene-1,2-diol

RHEA:31587 FMNH2 + O2 + uracil = (Z)-3-ureidoacrylate peracid + FMN + H(+)

RHEA:31679 O2 + prosolanapyrone II = H2O2 + prosolanapyrone III

RHEA:31695 (9Z,12Z)-octadecadienoate + O2 = (8E,10R,12Z)-10-hydroperoxyoctadeca-8,12-dienoate

RHEA:31927 3-hydroxyindolin-2-one + O2 + reduced [NADPH--hemoprotein reductase] = 2-hydroxy-2H-1,4-benzoxazin-3(4H)-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:31939 2-hydroxy-2H-1,4-benzoxazin-3(4H)-one + O2 + reduced [NADPH--hemoprotein reductase] = DIBOA + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:31943 cholest-4-en-3-one + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = (25S)-3-oxocholest-4-en-26-ol + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]

RHEA:31947 ent-isokaurene + O2 + reduced [NADPH--hemoprotein reductase] = ent-isokauren-2beta-ol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:32171 H(+) + NADPH + O2 + phenylacetyl-CoA = 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA + H2O + NADP(+)

RHEA:32283 3-hydroxyanthranilate + O2 = H(+) + H2O + quinolinate

RHEA:32491 (1E,4E,8E)-alpha-humulene + O2 + reduced [NADPH--hemoprotein reductase] = 10-hydroxy-alpha-humulene + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:32503 linalool + O2 + reduced [NADPH--hemoprotein reductase] = (6E)-8-hydroxylinalool + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:32635 linalool + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = (6E)-8-oxolinalool + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]

RHEA:32639 (6E)-8-hydroxylinalool + O2 + reduced [NADPH--hemoprotein reductase] = (6E)-8-oxolinalool + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:32683 5-hydroxymethylfurfural + 2 H2O + 3 O2 = 2,5-dicarboxyfuran + 2 H(+) + 3 H2O2

RHEA:32999 (+)-amorpha-4,11-diene + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = (+)-artemisinate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]

RHEA:33003 (+)-amorpha-4,11-diene + O2 + reduced [NADPH--hemoprotein reductase] = (+)-artemisinic alcohol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:33007 (+)-artemisinic alcohol + O2 + reduced [NADPH--hemoprotein reductase] = (+)-artemisinic aldehyde + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:33011 (+)-artemisinic aldehyde + O2 + reduced [NADPH--hemoprotein reductase] = (+)-artemisinate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:33043 (1R,4R)-camphor + H(+) + NADPH + O2 = (+)-6-exo-hydroxycamphor + H2O + NADP(+)

RHEA:33279 L-tryptophan + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = (E)-(indol-3-yl)acetaldehyde oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]

RHEA:33467 ergosta-5,7,24(28)-trien-3beta-ol + H(+) + NADPH + O2 = ergosta-5,7,22,24(28)-tetraen-3beta-ol + 2 H2O + NADP(+)

RHEA:33519 2 [Fe(II)-cytochrome b5] + 2 H(+) + O2 + sphinganine = 4-hydroxysphinganine + 2 [Fe(III)-cytochrome b5] + H2O

RHEA:33599 2 [Fe(II)-cytochrome b5] + 2 H(+) + N-hexacosanoylsphinganine + O2 = 2 [Fe(III)-cytochrome b5] + H2O + N-(hexacosanoyl)-(4R)-hydroxysphinganine

RHEA:33915 4-(methylamino)butanoate + H2O + O2 = H2O2 + methylamine + succinate semialdehyde

RHEA:33927 4-(6-hydroxypyridin-3-yl)-4-oxobutanoate + 2 H(+) + 2 NADH + O2 = 2,5-dihydroxypyridine + H2O + 2 NAD(+) + succinate semialdehyde

RHEA:33931 all-trans-zeaxanthin + O2 = (3R)-11-cis-3-hydroxyretinal + (3R)-all-trans-3-hydroxyretinal

RHEA:33935 2 N(omega)-hydroxy-L-arginine + NADH + 2 O2 = H(+) + 2 H2O + 2 L-citrulline + NAD(+) + 2 nitric oxide

RHEA:33939 H(+) + L-arginine + NADH + O2 = H2O + N(omega)-hydroxy-L-arginine + NAD(+)

RHEA:33943 H(+) + 2 L-arginine + 3 NADH + 4 O2 = 4 H2O + 2 L-citrulline + 3 NAD(+) + 2 nitric oxide

RHEA:34047 6'''-deamino-6'''-hydroxyneomycin C + O2 = 6'''-deamino-6'''-oxoneomycin C + H2O2

RHEA:34287 2 L-dopa + O2 = 2 H2O + 2 L-dopaquinone

RHEA:34307 4-nitrocatechol + NADPH + O2 = 2-hydroxy-1,4-benzoquinone + H2O + NADP(+) + nitrite

RHEA:34311 4-nitrocatechol + NADH + O2 = 2-hydroxy-1,4-benzoquinone + H2O + NAD(+) + nitrite

RHEA:34619 1-deoxypentalenate + 2-oxoglutarate + O2 = 1-deoxy-11beta-hydroxypentalenate + CO2 + succinate

RHEA:34807 (R)-dihydrocamalexate + O2 + reduced [NADPH--hemoprotein reductase] = camalexin + CO2 + 2 H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:35055 3,6-dichlorocatechol + O2 = (2E,4E)-2,5-dichloromuconate + H(+)

RHEA:35307 H(+) + NADH + O2 + salicylate = 2,5-dihydroxybenzoate + H2O + NAD(+)

RHEA:35531 cyclo(L-phenylalanyl-L-leucyl) + 2 O2 = albonoursin + 2 H2O2

RHEA:35535 cyclo(L-phenylalanyl-L-leucyl) + O2 = cyclo[(Z)-alpha,beta-didehydrophenylalanyl-L-leucyl] + H2O2

RHEA:35539 cyclo[(Z)-alpha,beta-didehydrophenylalanyl-L-leucyl] + O2 = albonoursin + H2O2

RHEA:36255 (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + 1-O-(1,2-saturated-alkyl)-sn-glycerol + O2 = (6R)-L-erythro-6,7-dihydrobiopterin + a 1-(1-hydroxyalkyl)-sn-glycerol + H2O

RHEA:36631 D-ribulose 1,5-bisphosphate + O2 = 2-phosphoglycolate + 3-phospho-D-glycerate + 2 H(+)

RHEA:37039 5 AH2 + 2 H(+) + heme b + 4 O2 = 5 A + delta-staphylobilin + Fe(2+) + formaldehyde + 4 H2O

RHEA:37363 5 AH2 + 2 H(+) + heme b + 4 O2 = 5 A + beta-staphylobilin + Fe(2+) + formaldehyde + 4 H2O

RHEA:37423 aclacinomycin N + O2 = aclacinomycin A + H2O2

RHEA:37791 aclacinomycin A + O2 = aclacinomycin Y + H2O2

RHEA:37795 2 H(+) + 2 NADPH + O2 = 2 H2O + 2 NADP(+)

RHEA:37847 13-dihydrodaunorubicin + H(+) + NADPH + O2 = daunorubicin + 2 H2O + NADP(+)

RHEA:37851 13-deoxydaunorubicin + H(+) + NADPH + O2 = 13-dihydrodaunorubicin + H2O + NADP(+)

RHEA:37899 2-oxoglutarate + 7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + O2 = 7-(2-hydroxy-3-amino-3-carboxypropyl)wyosine(37) in tRNA(Phe) + CO2 + succinate

RHEA:38039 (9Z,12Z,15Z)-octadecatrienoyl-containing glycerolipid + 2 [Fe(II)-cytochrome b5] + 2 H(+) + O2 = 2 [Fe(III)-cytochrome b5] + a (5Z,9Z,12Z,15Z)-octadecatetraenoyl-containing glycerolipid + 2 H2O

RHEA:39087 decanedioyl-CoA + O2 = (2E)-decenedioyl-CoA + H2O2

RHEA:39295 (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA + AH2 + O2 = (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + A + 2 H2O

RHEA:39567 (11Z,14Z)-eicosadienoyl-CoA + AH2 + O2 = (8Z,11Z,14Z)-eicosatrienoyl-CoA + A + 2 H2O

RHEA:39571 (11Z,14Z,17Z)-eicosatrienoyl-CoA + AH2 + O2 = (8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA + A + 2 H2O

RHEA:39655 (7Z,10Z,13Z,16Z)-docosatetraenoyl-CoA + AH2 + O2 = (4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA + A + 2 H2O

RHEA:39671 (9Z)-hexadecenoyl-CoA + AH2 + O2 = (9Z,12Z)-hexadecadienoyl-CoA + A + 2 H2O

RHEA:40079 docosanoate + O2 + reduced [NADPH--hemoprotein reductase] = 22-hydroxydocosanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:40167 hexadecanoyl-CoA + O2 = (2E)-hexadecenoyl-CoA + H2O2

RHEA:40299 6-deoxyerythronolide B + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = erythronolide B + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]

RHEA:40459 (2S)-pristanoyl-CoA + O2 = (2E)-pristenoyl-CoA + H2O2

RHEA:40555 dTDP-beta-L-evernosamine + H(+) + 2 NADPH + 2 O2 = dTDP-2,3,6-trideoxy-3-C-methyl-4-O-methyl-3-nitroso-beta-L-arabino-hexopyranose + 3 H2O + 2 NADP(+)

RHEA:40563 dTDP-N-hydroxy-beta-L-evernosamine + H(+) + NADPH + O2 = dTDP-2,3,6-trideoxy-3-C-methyl-4-O-methyl-3-nitroso-beta-L-arabino-hexopyranose + 2 H2O + NADP(+)

RHEA:41211 (indol-3-yl)acetate + H(+) + NADH + O2 = (2-hydroxy-1H-indol-3-yl)acetate + H2O + NAD(+)

RHEA:41556 2-oxoglutarate + L-arginyl-[ribosomal protein uL16] + O2 = (3R)-3-hydroxy-L-arginyl-[ribosomal protein uL16] + CO2 + succinate

RHEA:42160 (11Z,14Z)-eicosadienoyl-CoA + AH2 + O2 = (5Z,11Z,14Z)-eicosatrienoyl-CoA + A + 2 H2O

RHEA:42164 (11Z,14Z,17Z)-eicosatrienoyl-CoA + AH2 + O2 = (5Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA + A + 2 H2O

RHEA:42208 an omega-(methylsulfanyl)-N-sulfo-alkylhydroximate S-glucoside + H(+) + NADPH + O2 = an omega-(methylsulfinyl)-alkyl-glucosinolate + H2O + NADP(+)

RHEA:42492 3'-N-debenzoyl-2'-deoxytaxol + AH2 + O2 = 3'-N-debenzoyltaxol + A + H2O

RHEA:42676 L-cysteine + L-histidine + O2 = H2O + L-alanin-3-yl L-histidin-5-yl sulfoxide

RHEA:42820 2 H(+) + 2 NADPH + 2 O2 + tetracenomycin A2 = H2O + 2 NADP(+) + tetracenomycin C

RHEA:42824 2 H(+) + 2 NADH + 2 O2 + tetracenomycin A2 = H2O + 2 NAD(+) + tetracenomycin C

RHEA:43072 beta-amyrin + O2 + reduced [NADPH--hemoprotein reductase] = erythrodiol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:43076 erythrodiol + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + 2 H2O + oleanolic aldehyde + oxidized [NADPH--hemoprotein reductase]

RHEA:43080 O2 + oleanolic aldehyde + reduced [NADPH--hemoprotein reductase] = 2 H(+) + H2O + oleanolate + oxidized [NADPH--hemoprotein reductase]

RHEA:43472 (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 = 14-hydroperoxy-(4Z,7Z,10Z,12E,16Z,19Z)-docosahexaenoate

RHEA:43592 all-trans-zeaxanthin + O2 = (3R)-3-hydroxy-8'-apo-beta-carotenal + 3beta-hydroxy-beta-cyclocitral

RHEA:43596 (3R)-3-hydroxy-8'-apo-beta-carotenal + O2 = 3beta-hydroxy-beta-cyclocitral + crocetin dialdehyde

RHEA:43896 3beta-hydroxy-5alpha-androstan-17-one + H(+) + NADPH + O2 = 3beta,7alpha-dihydroxy-5alpha-androstan-17-one + H2O + NADP(+)

RHEA:43996 2-oxoglutarate + 3-methyl fatty acyl-CoA + O2 = 2-hydroxy-3-methyl fatty acyl-CoA + CO2 + succinate

RHEA:44000 2-oxoglutarate + 3-methylhexadecanoyl-CoA + O2 = 2-hydroxy-3-methylhexadecanoyl-CoA + CO2 + succinate

RHEA:45044 2 [Fe(II)cytochrome c] + H(+) + nitroxyl + O2 = 2 [Fe(III)cytochrome c] + H2O + nitrite

RHEA:45288 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + 2 O2 = 2-glyceryl-prostaglandin G2

RHEA:46192 3beta-hydroxyandrost-5-en-17-one + H(+) + NADPH + O2 = 3beta,7alpha-dihydroxyandrost-5-en-17-one + H2O + NADP(+)

RHEA:46196 H(+) + NADPH + O2 + pregnenolone = 7alpha-hydroxypregnenolone + H2O + NADP(+)

RHEA:46236 2 [Fe(II)-cytochrome b5] + a (9Z,12Z)-octadecadienoyl-containing glycerolipid + 2 H(+) + O2 = 2 [Fe(III)-cytochrome b5] + a (5Z,9Z,12Z)-octadecatrienoyl-containing glycerolipid + 2 H2O

RHEA:46304 O2 + reduced [NADPH--hemoprotein reductase] + testosterone = 16beta,17beta-dihydroxyandrost-4-en-3-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:46396 2 [Fe(II)-cytochrome b5] + an 11,12-saturated fatty acyl-CoA + 2 H(+) + O2 = 2 [Fe(III)-cytochrome b5] + an (11E)-Delta(11)-fatty acyl-CoA + 2 H2O

RHEA:46440 a (9Z,12Z)-octadecadienoyl-containing glycerolipid + AH2 + O2 = A + a (8E,10E,12Z)-octadecatrienoyl-containing glycerolipid + 2 H2O

RHEA:46500 2-oxoglutarate + O2 + UMP = CO2 + phosphate + succinate + uridine-5'-aldehyde

RHEA:46524 (11Z,14Z)-eicosadienoyl-CoA + 2 [Fe(II)-cytochrome b5] + 2 H(+) + O2 = (5Z,11Z,14Z)-eicosatrienoyl-CoA + 2 [Fe(III)-cytochrome b5] + 2 H2O

RHEA:46528 (11Z,14Z,17Z)-eicosatrienoyl-CoA + 2 [Fe(II)-cytochrome b5] + 2 H(+) + O2 = (5Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA + 2 [Fe(III)-cytochrome b5] + 2 H2O

RHEA:46532 2 [Fe(II)-cytochrome b5] + a (9Z,12Z)-octadecadienoyl-containing glycerolipid + 2 H(+) + O2 = 2 [Fe(III)-cytochrome b5] + a (9Z,11E,13Z)-octadeca-9,11,13-trienoyl-containing glycerolipid + 2 H2O

RHEA:46552 2 [Fe(II)-cytochrome b5] + a (9Z,12Z)-octadecadienoyl-containing glycerolipid + 2 H(+) + O2 = 2 [Fe(III)-cytochrome b5] + a (9Z)-octadec-9-en-12-ynoyl-containing glycerolipid + 2 H2O

RHEA:46728 (25S)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA + O2 = (24E)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-en-26-oyl-CoA + H2O2

RHEA:46772 1-octadecanoyl 2-acyl-glycerolipid + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = a 1-[(9Z)-octadecenoyl]-2-acyl-glycerolipid + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]

RHEA:46792 2 [Fe(II)-cytochrome b5] + an (11Z,14Z)-icosadienoyl-containing glycerolipid + 2 H(+) + O2 = 2 [Fe(III)-cytochrome b5] + an (8Z,11Z,14Z)-icosatrienoyl-containing glycerolipid + 2 H2O

RHEA:46796 2 [Fe(II)-cytochrome b5] + an (11Z,14Z,17Z)-icosatrienoyl-containing glycerolipid + 2 H(+) + O2 = 2 [Fe(III)-cytochrome b5] + an (8Z,11Z,14Z,17Z)-eicosatetraenoyl-containing glycerolipid + 2 H2O

RHEA:46976 (S)-6-hydroxynicotine + O2 = 6-hydroxy-N-methylmyosmine + H2O2

RHEA:46988 (R)-6-hydroxynicotine + O2 = 6-hydroxy-N-methylmyosmine + H2O2

RHEA:47224 3beta-sulfooxy-androst-5-en-17-one + H(+) + NADPH + O2 = 3beta-sulfooxy-16alpha-hydroxy-androst-5-en-17-one + H2O + NADP(+)

RHEA:47616 ethionamide + H(+) + NADPH + O2 = ethionamide S-oxide + H2O + NADP(+)

RHEA:47620 2-ethylhexyl sulfate + 2-oxoglutarate + O2 = 2-ethylhexanal + CO2 + H(+) + succinate + sulfate

RHEA:48584 2 H2O + 2 leukotriene A4 + O2 = 2 lipoxin A4

RHEA:48652 lipoxin B4 + O2 + reduced [NADPH--hemoprotein reductase] = 20-hydroxy-lipoxin B4 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:48836 (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + AH2 + O2 = (18R)-hydroxy-(5Z,8Z,11Z,14Z,16E)-eicosapentaenoate + A + H2O

RHEA:48852 (7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + AH2 + O2 = 13R-hydroxy-(7Z,10Z,14E,16Z,19Z)-docosapentaenoate + A + H2O

RHEA:48992 1,3,7-trimethylurate + H(+) + NADH + O2 = 1,3,7-trimethyl-5-hydroxyisourate + H2O + NAD(+)

RHEA:49204 20S-hydroxycholecalciferol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = 20S,24R-dihydroxycholecalciferol + H2O + 2 oxidized [adrenodoxin]

RHEA:49208 20S-hydroxycholecalciferol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = 20S,24S-dihydroxycholecalciferol + H2O + 2 oxidized [adrenodoxin]

RHEA:49376 12-hydroxyoctadecanoate + O2 + reduced [NADPH--hemoprotein reductase] = 12,18-dihydroxyoctadecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:50008 6-methylpretetramide + 2 H(+) + NADPH + O2 = 4-hydroxy-6-methylpretetramide + H2O + NADP(+)

RHEA:50228 FADH2 + O2 + resorcinol = benzene-1,2,4-triol + FAD + H(+) + H2O

RHEA:50292 all-trans-retinol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = all-trans-3,4-didehydroretinol + 2 H2O + 2 oxidized [adrenodoxin]

RHEA:50340 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] + testosterone = 1alpha-hydroxytestosterone + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]

RHEA:50368 2-methylbutan-2-ol + H(+) + NADPH + O2 = 3-hydroxy-3-methylbut-1-ene + 2 H2O + NADP(+)

RHEA:50388 5a,11a-dehydrotetracycline + H(+) + NADPH + O2 = 5a,11a-dehydrooxytetracycline + H2O + NADP(+)

RHEA:50444 (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + 2 O2 = prostaglandin G3

RHEA:50712 chloride + FADH2 + O2 + tetracycline = 7-chlorotetracycline + FAD + H(+) + 2 H2O

RHEA:50716 dimethyl sulfone + FMNH2 + O2 = FMN + formaldehyde + 2 H(+) + H2O + methanesulfinate

RHEA:50812 androst-4-ene-3,17-dione + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = 1alpha-hydroxyandrost-4-ene-3,17-dione + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]

RHEA:50848 (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + AH2 + O2 = (11R)-hydroxy-(5Z,8Z,12E,14Z,17Z)-eicosapentaenoate + A + H2O

RHEA:50852 (5Z,8Z,11Z,14Z)-eicosatetraenoate + AH2 + O2 = (11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoate + A + H2O

RHEA:50856 (5Z,8Z,11Z,14Z)-eicosatetraenoate + AH2 + O2 = (15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + A + H2O

RHEA:50860 (9Z,12Z)-octadecadienoate + AH2 + O2 = 13-hydroxy-(9Z,11E)-octadecadienoate + A + H2O

RHEA:50864 (9Z,12Z)-octadecadienoate + AH2 + O2 = 9-hydroxy-(10E,12Z)-octadecadienoate + A + H2O

RHEA:50932 (8S)-hydroperoxy-(5Z,9E,11Z,14Z)-eicosatetraenoate + O2 = (8S,15S)-dihydroperoxy-(5Z,9E,11Z,13E)-eicosatetraenoate

RHEA:51244 (9Z,12Z,15Z)-octadecatrienoate + O2 = (13R)-hydroperoxy-(9Z,11E,15Z)-octadecatrienoate

RHEA:51256 (9S)-hydroperoxy-(10E,12Z,15Z)-octadecatrienoate + O2 = (9S,16S)-dihydroperoxy-(10E,12Z,14E)-octadecatrienoate

RHEA:51404 H2O + L-arginine + O2 = 5-guanidino-2-oxopentanoate + H2O2 + NH4(+)

RHEA:51440 (9Z,12Z,15Z)-octadecatrienoate + O2 = (11S)-hydroperoxy-(9Z,12Z,15Z)-octadecatrienoate

RHEA:51508 2-oxoglutarate + L-proline + O2 = CO2 + succinate + trans-4-hydroxy-L-proline

RHEA:51568 (25S)-3-oxocholest-4-en-26-ol + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = (25S)-3-oxocholest-4-en-26-al + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]

RHEA:51572 (25S)-3-oxocholest-4-en-26-al + H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = (25S)-3-oxocholest-4-en-26-oate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]

RHEA:51948 (2S)-2-methylbutanenitrile + O2 + reduced [NADPH--hemoprotein reductase] = 2-hydroxy-2-methylbutanenitrile + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:51952 (E)-2-methylpropanal oxime + O2 + reduced [NADPH--hemoprotein reductase] = 2-hydroxy-2-methylpropanenitrile + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:51964 2-methylpropanenitrile + O2 + reduced [NADPH--hemoprotein reductase] = 2-hydroxy-2-methylpropanenitrile + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:52740 glyphosate + H2O + O2 = aminomethylphosphonate + glyoxylate + H(+) + H2O2

RHEA:52836 H(+) + indole + NADH + O2 = H2O + indoxyl + NAD(+)

RHEA:53736 a 2-halobenzoate + H(+) + NADH + O2 = a halide anion + catechol + CO2 + NAD(+)

RHEA:53776 3-mercaptopropanoate + O2 = 3-sulfinopropanoate + H(+)

RHEA:53892 an S-prenyl-L-cysteine + H2O + O2 = a prenal + H2O2 + L-cysteine

RHEA:53960 4-(gamma-L-glutamylamino)butanoy-[BtrI ACP] + FMNH2 + O2 = 4-(gamma-L-glutamylamino)-(2S)-2-hydroxybutanoyl-[BtrI ACP] + FMN + H(+) + H2O

RHEA:54144 2 2-oxoglutarate + 5-methylcytidine(34) in mitochondrial tRNA(Met) + 2 O2 = 5-formylcytidine(34) in mitochondrial tRNA(Met) + 2 CO2 + H2O + 2 succinate

RHEA:54256 2-oxoglutarate + L-histidyl-[protein] + O2 = (3S)-3-hydroxy-L-histidyl-[protein] + CO2 + succinate

RHEA:54872 (1S,4R)-menthone + H(+) + NADPH + O2 = (4S,7R)-7-isopropyl-4-methyloxepan-2-one + H2O + NADP(+)

RHEA:54992 3 A + FMN + H2O + L-glutamate + O2 = 2-oxoglutarate + 8-amino-8-demethylriboflavin 5'-phosphate + 3 AH2 + CO2 + H(+)

RHEA:55244 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + 6 [Fe(II)-cytochrome b5] + 5 H(+) + 3 O2 = 4alpha-carboxyl-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol + 6 [Fe(III)-cytochrome b5] + 4 H2O

RHEA:55432 11-hydroxyferruginol + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = carnosate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]

RHEA:55452 beta-amyrin + O2 + reduced [NADPH--hemoprotein reductase] = daturadiol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:55480 ent-cassa-12,15-diene + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = ent-3beta-hydroxycassa-12,15-dien-2-one + 3 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]

RHEA:55488 ent-cassa-12,15-dien-2beta-ol + O2 + reduced [NADPH--hemoprotein reductase] = ent-cassa-12,15-dien-2-one + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:55492 ent-cassa-12,15-dien-2-one + O2 + reduced [NADPH--hemoprotein reductase] = ent-3beta-hydroxycassa-12,15-dien-2-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:55496 ent-cassa-12,15-dien-2beta-ol + O2 + reduced [NADPH--hemoprotein reductase] = ent-cassa-12,15-dien-2beta,3beta-ol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:55500 ent-cassa-12,15-dien-2beta,3beta-ol + O2 + reduced [NADPH--hemoprotein reductase] = ent-3beta-hydroxycassa-12,15-dien-2-one + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:55528 H(+) + H2O + L-tyrosine + O2 = (4-hydroxyphenyl)acetaldehyde + CO2 + H2O2 + NH4(+)

RHEA:55756 2-oxoglutarate + an N(2)-[(3R)-3-(2-saturated-acyloxy)acyl]-L-ornithine lipid + O2 = a 2-hydroxyornithine lipid + CO2 + succinate

RHEA:55896 chloride + FADH2 + L-tryptophan + O2 = 5-chloro-L-tryptophan + FAD + 2 H2O

RHEA:55900 chloride + FADH2 + L-tryptophan + O2 = 6-chloro-L-tryptophan + FAD + 2 H2O

RHEA:55956 (9Z)-octadecenoate + AH2 + O2 = (12R)-hydroxy-(9Z)-octadecenoate + A + H2O

RHEA:56172 FMN + O2 = 8-demethyl-8-formylriboflavin 5'-phosphate + H2O

RHEA:56336 ent-isokaurene + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = ent-isokaurene-2beta,3beta-diol + 2 H(+) + 2 H2O + 2 oxidized [NADPH--hemoprotein reductase]

RHEA:56340 ent-isokauren-2beta-ol + O2 + reduced [NADPH--hemoprotein reductase] = ent-isokaurene-2beta,3beta-diol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:56360 13-deoxycarminomycin + H(+) + NADPH + O2 = 13-dihydrocarminomycin + H2O + NADP(+)

RHEA:56364 13-dihydrocarminomycin + H(+) + NADPH + O2 = carminomycin + 2 H2O + NADP(+)

RHEA:56528 chloride + D-tryptophan + FADH2 + O2 = 6-chloro-D-tryptophan + FAD + 2 H2O

RHEA:56680 beta-dihydromenaquinone-9 + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = H2O + omega-hydroxy-beta-dihydromenaquinone-9 + 2 oxidized [2Fe-2S]-[ferredoxin]

RHEA:56684 dihydrorhizobitoxine + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin] + rhizobitoxine

RHEA:56764 12-epi-fischerindole U + 2-oxoglutarate + chloride + H(+) + O2 = 12-epi-fischerindole G + CO2 + H2O + succinate

RHEA:56768 2 AH2 + all-trans-zeaxanthin + 2 O2 = 2 A + all-trans-adonixanthin + 3 H2O

RHEA:56772 2 AH2 + all-trans-adonixanthin + 2 O2 = 2 A + all-trans-(3S,3'S)-astaxanthin + 3 H2O

RHEA:56840 5-amino-2-hydroxybenzoate + O2 = (2Z,4E)-4-amino-6-oxohepta-2,4-dienedioate + H(+)

RHEA:57332 H2O + 3 O2 + 3 propionate 3-nitronate = 3 3-oxopropanoate + 3 H(+) + H2O2 + 2 nitrate + nitrite

RHEA:57356 2-oxoglutarate + chloride + H(+) + hapalindole U + O2 = CO2 + H2O + hapalindole G + succinate

RHEA:57376 (S)-N-methylcanadine + O2 + reduced [NADPH--hemoprotein reductase] = (S)-1-hydroxy-N-methylcanadine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:57380 (S)-1-hydroxy-N-methylcanadine + O2 + reduced [NADPH--hemoprotein reductase] = (13S,14R)-1,13-dihydroxy-N-methylcanadine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:57388 (13S,14R)-13-O-acetyl-1-hydroxy-N-methylcanadine + O2 + reduced [NADPH--hemoprotein reductase] = (13S,14R)-13-O-acetyl-1,8-dihydroxy-N-methylcanadine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:57544 (S)-beta-macrocarpene + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase] + zealexin A1

RHEA:57548 (S)-beta-macrocarpene + O2 + reduced [NADPH--hemoprotein reductase] = [(4S)-4-(5,5-dimethylcyclohex-1-en-1-yl)-cyclohex-1-en-1-yl]methanol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:57552 [(4S)-4-(5,5-dimethylcyclohex-1-en-1-yl)-cyclohex-1-en-1-yl]methanol + O2 + reduced [NADPH--hemoprotein reductase] = (4S)-4-(5,5-dimethylcyclohex-1-en-1-yl)cyclohex-1-ene-1-carbaldehyde + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:57556 (4S)-4-(5,5-dimethylcyclohex-1-en-1-yl)cyclohex-1-ene-1-carbaldehyde + O2 + reduced [NADPH--hemoprotein reductase] = 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + zealexin A1

RHEA:57584 a flavanone + O2 + reduced [NADPH--hemoprotein reductase] = a 2-hydroxyflavanone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:57588 (S)-naringenin + O2 + reduced [NADPH--hemoprotein reductase] = (2S)-2-hydroxynaringenin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:57592 (S)-pinocembrin + O2 + reduced [NADPH--hemoprotein reductase] = (2S)-2-hydroxypinocembrin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:57596 (S)-eriodictyol + O2 + reduced [NADPH--hemoprotein reductase] = (2S)-2hydroxyeriodictyol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:57620 dihydro-ML-236C carboxylate + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + 2 H2O + ML-236C carboxylate + oxidized [NADPH--hemoprotein reductase]

RHEA:57624 dihydro-ML-236C carboxylate + O2 + reduced [NADPH--hemoprotein reductase] = 3alpha-hydroxy-3,5-dihydro-ML-236C carboxylate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:57632 ML-236C carboxylate + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + ML-236A carboxylate + oxidized [NADPH--hemoprotein reductase]

RHEA:57848 2-oxoglutarate + O2 + scopoletin = CO2 + fraxetin + succinate

RHEA:57856 2-oxoglutarate + O2 + trans-feruloyl-CoA = 6'-hydroxy-trans-feruloyl-CoA + CO2 + succinate

RHEA:58348 2 2-oxoglutarate + N(omega),N(omega)'-dimethyl-L-arginyl-[protein] + 2 O2 = 2 CO2 + 2 formaldehyde + L-arginyl-[protein] + 2 succinate

RHEA:58352 2-oxoglutarate + N(omega),N(omega)-dimethyl-L-arginyl-[protein] + O2 = CO2 + formaldehyde + N(omega)-methyl-L-arginyl-[protein] + succinate

RHEA:58356 2-oxoglutarate + N(omega)-methyl-L-arginyl-[protein] + O2 = CO2 + formaldehyde + L-arginyl-[protein] + succinate

RHEA:58392 4-amino-3-all-trans-hexaprenylbenzoate + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = 4-amino-5-hydroxy-3-all-trans-hexaprenylbenzoate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]

RHEA:58468 2 2-oxoglutarate + N(omega),N(omega)-dimethyl-L-arginyl-[protein] + 2 O2 = 2 CO2 + 2 formaldehyde + L-arginyl-[protein] + 2 succinate

RHEA:58472 2-oxoglutarate + N(omega),N(omega)'-dimethyl-L-arginyl-[protein] + O2 = CO2 + formaldehyde + N(omega)-methyl-L-arginyl-[protein] + succinate

RHEA:10036 4-hydroxy-3-methoxy-benzenemethanol + O2 = 4-hydroxy-3-methoxybenzaldehyde + H2O2

RHEA:10084 3,4-dihydroxybenzoate + O2 = 3-carboxy-cis,cis-muconate + 2 H(+)

RHEA:10124 H(+) + NADPH + O2 + phenylacetone = benzyl acetate + H2O + NADP(+)

RHEA:10448 2-oxoglutarate + a flavanone + O2 = a flavone + CO2 + H2O + succinate

RHEA:10592 a 3',5'-unsubstituted flavanone + O2 + reduced [NADPH--hemoprotein reductase] = a 3'-hydroxy,5'-unsubstituted flavanone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:10784 2-oxoglutarate + N(6)-methyl-L-lysine(36)-[histone H3] + O2 = CO2 + formaldehyde + L-lysine(36)-[histone H3] + succinate

RHEA:10796 albendazole + H(+) + NADPH + O2 = albendazole S-oxide + H2O + NADP(+)

RHEA:11420 NADPH + O2 + senecionine = H2O + NADP(+) + senecionine N-oxide

RHEA:11428 beta-D-glucose + O2 = D-glucono-1,5-lactone + H2O2

RHEA:11436 4 [Fe(II)cytochrome c] + 4 H(+) + O2 = 4 [Fe(III)cytochrome c] + 2 H2O

RHEA:11880 (S)-6-hydroxynicotine + H2O + O2 = 6-hydroxypseudooxynicotine + H2O2

RHEA:11972 4 Fe(2+) + 6 H2O + O2 = 12 H(+) + 4 iron(III) oxide-hydroxide

RHEA:12200 2'-deoxymugineate + 2-oxoglutarate + O2 = CO2 + mugineate + succinate

RHEA:12352 L-gulono-1,4-lactone + O2 = H2O2 + L-xylo-hex-3-ulonolactone

RHEA:12496 2 Fe(2+) + 4 H2O + O2 = 6 H(+) + H2O2 + 2 iron(III) oxide-hydroxide

RHEA:12568 4-nitrophenol + H(+) + NADH + O2 = 4-nitrocatechol + H2O + NAD(+)

RHEA:12897 2-cis-(+)-abscisate + O2 + reduced [NADPH--hemoprotein reductase] = (+)-8'-hydroxyabscisate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:13045 ent-kaur-16-ene + O2 + reduced [NADPH--hemoprotein reductase] = ent-kaur-16-en-19-ol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:13313 H2O + O2 + sarcosine = formaldehyde + glycine + H2O2

RHEA:13545 (6E,10E)-geranyllinalool + O2 + reduced [NADPH--hemoprotein reductase] = (3E,7E)-4,8,12-trimethyltrideca 1,3,7,11-tetraene + but-3-en-2-one + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:13773 (S)-cheilanthifoline + O2 + reduced [NADPH--hemoprotein reductase] = (S)-stylopine + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:14021 AH2 + ecdysone + O2 = 20-hydroxyecdysone + A + H2O

RHEA:14049 AH2 + O2 + taxa-4,11-diene = A + H2O + taxa-4(20),11-dien-5alpha-ol

RHEA:14133 O2 + reduced [NADPH--hemoprotein reductase] + tabersonine = 16-hydroxytabersonine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:14181 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysine + O2 = (3S)-3-hydroxy-N(6),N(6),N(6)-trimethyl-L-lysine + CO2 + succinate

RHEA:14837 glyoxylate + H2O + O2 = H(+) + H2O2 + oxalate

RHEA:14985 (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = (8R)-hydroperoxy-(5Z,9E,11Z,14Z)-eicosatetraenoate

RHEA:15129 (4S)-limonene + O2 + reduced [NADPH--hemoprotein reductase] = (1S,6R)-isopiperitenol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:15629 a steroid + 2 H(+) + O2 + 2 reduced [adrenodoxin] = an 11beta-hydroxysteroid + H2O + 2 oxidized [adrenodoxin]

RHEA:15737 cyclopentanone + H(+) + NADPH + O2 = 5-valerolactone + H2O + NADP(+)

RHEA:15993 anthraniloyl-CoA + 2 H(+) + 2 NADPH + O2 = 2-amino-5-oxocyclohex-1-enecarbonyl-CoA + H2O + 2 NADP(+)

RHEA:15997 anthraniloyl-CoA + 2 H(+) + 2 NADH + O2 = 2-amino-5-oxocyclohex-1-enecarbonyl-CoA + H2O + 2 NAD(+)

RHEA:16337 a 3'-unsubstituted flavone + O2 + reduced [NADPH--hemoprotein reductase] = a 3'-hydroxyflavone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:16789 a (2S)-2-hydroxycarboxylate + O2 = a 2-oxocarboxylate + H2O2

RHEA:17061 H(+) + NADPH + O2 + phenol = catechol + H2O + NADP(+)

RHEA:17337 catechol + O2 = (2Z,4E)-2-hydroxy-6-oxohexa-2,4-dienoate + H(+)

RHEA:17945 (4S)-limonene + O2 + reduced [NADPH--hemoprotein reductase] = (1S,5R)-carveol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:18117 L-tyrosine + O2 = H2O + L-dopaquinone

RHEA:18165 biphenyl + H(+) + NADH + O2 = (2R,3S)-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD(+)

RHEA:18237 2,5-dihydroxybenzoate + O2 = 3-maleylpyruvate + H(+)

RHEA:18401 (E)-4-hydroxyphenylacetaldehyde oxime + O2 + reduced [NADPH--hemoprotein reductase] = (S)-4-hydroxymandelonitrile + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:18797 a 3'-hydroxy,5'-unsubstituted flavanone + O2 + reduced [NADPH--hemoprotein reductase] = a 3',5'-dihydroxyflavanone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:18857 lithocholate + O2 + reduced [NADPH--hemoprotein reductase] = 6beta-hydroxylithocholate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:18949 O2 + reduced [NADPH--hemoprotein reductase] + taxa-4(20),11-dien-5alpha-ol = H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + taxa-4(20),11-dien-5alpha,13alpha-diol

RHEA:19885 (S)-reticuline + O2 = (S)-scoulerine + H(+) + H2O2

RHEA:20265 2-oxoglutarate + L-proline + O2 = cis-3-hydroxy-L-proline + CO2 + succinate

RHEA:20441 L-cysteine + O2 = 3-sulfino-L-alanine + H(+)

RHEA:20485 (S)-scoulerine + O2 + reduced [NADPH--hemoprotein reductase] = (S)-cheilanthifoline + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:20529 2-cis-(+)-abscisic aldehyde + H2O + O2 = 2-cis-(+)-abscisate + H(+) + H2O2

RHEA:20696 2 H(+) + 2 superoxide = H2O2 + O2

RHEA:20748 2-oxoglutarate + O2 + penicillin N = CO2 + deacetoxycephalosporin C + H2O + succinate

RHEA:20980 2 bilirubin IXalpha + O2 = 2 biliverdin IXalpha + 2 H2O

RHEA:21104 AH2 + cholesterol + O2 = 25-hydroxycholesterol + A + H2O

RHEA:21280 H2O + 2 O2 + thiamine = H(+) + 2 H2O2 + thiamine acetate

RHEA:21304 ent-kaur-16-en-19-ol + O2 + reduced [NADPH--hemoprotein reductase] = ent-kaur-16-en-19-al + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:21452 a [peptide]-C-terminal glycine + L-ascorbate + O2 = a [peptide]-C-terminal 2-hydroxyglycine + H2O + L-dehydroascorbate

RHEA:21788 2-oxoglutarate + N(6),N(6)-dimethyl-L-lysine(36)-[histone H3] + O2 = CO2 + formaldehyde + N(6)-methyl-L-lysine(36)-[histone H3] + succinate

RHEA:22136 7(1)-hydroxychlorophyllide a + H(+) + NADPH + O2 = chlorophyllide b + 2 H2O + NADP(+)