Rhea results for: CHEBI:16526

Number of hits: 767

Information:
The query resolved to the following ChEBI compounds (by name): none

Accession Equation / Hits details Other directions
RHEA:27610 formate + H(+) = CO2 + H2

RHEA:17829 A + CO + H2O = AH2 + CO2

RHEA:18697 3-(4-hydroxyphenyl)pyruvate + H(+) = (4-hydroxyphenyl)acetaldehyde + CO2

RHEA:20501 H(+) + 2 pyruvate = 2-acetolactate + CO2

RHEA:20669 3beta-hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carboxylate + NAD(+) = 4alpha-methyl-5alpha-cholest-7-en-3-one + CO2 + NADH

RHEA:20673 3beta-hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carboxylate + NADP(+) = 4alpha-methyl-5alpha-cholest-7-en-3-one + CO2 + NADPH

RHEA:25767 3-carboxy-2-oxobutanoate + H(+) = 2-oxobutanoate + CO2

RHEA:29067 formate + H(+) + menaquinone-8 = CO2 + menaquinol-8

RHEA:31107 3-phenylpyruvate + O2 = (2-hydroxyphenyl)acetate + CO2

RHEA:31219 5-hydroxykynurenamine + CO2 = 5-hydroxy-L-kynurenine + H(+)

RHEA:31239 4 H(+) + uroporphyrinogen I = 4 CO2 + coproporphyrinogen I

RHEA:31447 6-amino-2-oxohexanoate + H2O2 = 5-aminopentanoate + CO2 + H2O

RHEA:42572 3-carboxy-2-hydroxy-7-methyl-6-oxo-(2Z,4Z)-octadienoate + H(+) = 2-hydroxy-7-methyl-6-oxo-(2E,4E)-octadienoate + CO2

RHEA:44768 3-methoxy-4-hydroxy-5-all-trans-hexaprenylbenzoate + H(+) = 2-methoxy-6-(all-trans-hexaprenyl)phenol + CO2

RHEA:12629 2-oxoglutarate + L-hyoscyamine + O2 = (6S)-6-hydroxyhyoscyamine + CO2 + succinate

RHEA:13385 3-oxododecanoate + H(+) = 2-undecanone + CO2

RHEA:13845 dihydroxyfumarate + H(+) = 2-hydroxy-3-oxopropanoate + CO2

RHEA:13885 H2O + stipitatonate = CO2 + stipitatate

RHEA:14073 3-hydroxy-L-glutamate + H(+) = 4-amino-3-hydroxybutanoate + CO2

RHEA:15077 H(+) + N-[(R)-pantothenoyl]-L-cysteine = (R)-pantetheine + CO2

RHEA:16557 2-amino-3-carboxymuconate 6-semialdehyde + H(+) = 2-aminomuconate 6-semialdehyde + CO2

RHEA:17685 H(+) + uracil 5-carboxylate = CO2 + uracil

RHEA:17757 H(+) + L-methionine = 3-(methylsulfanyl)propanamine + CO2

RHEA:17965 (R)-2-hydroperoxy-(9Z,12Z,15Z)-octadecatrienoate + H(+) = (8Z,11Z,14Z)-heptadecatrienal + CO2 + H2O

RHEA:18365 (R)-malate + NAD(+) = CO2 + NADH + pyruvate

RHEA:18989 H(+) + L-valine = 2-methylpropan-1-amine + CO2

RHEA:19333 H(+) + oxalyl-CoA = CO2 + formyl-CoA

RHEA:19445 2,3-dihydroxyindole + O2 = anthranilate + CO2 + H(+)

RHEA:19809 (S)-ureidoglycolate + 2 H(+) + H2O = CO2 + glyoxylate + 2 NH4(+)

RHEA:20561 3-hydroxypyruvate + H(+) = CO2 + glycolaldehyde

RHEA:20712 H(+) + heptanedioyl-CoA + L-alanine = 8-amino-7-oxononanoate + CO2 + CoA

RHEA:20840 H(+) + L-histidine = CO2 + histamine

RHEA:21312 2,5-dihydroxybenzoate + H(+) = CO2 + hydroquinone

RHEA:21576 carnitine + H(+) = 2-methylcholine + CO2

RHEA:22224 3 H(+) + 3 malonyl-CoA + N-methylanthraniloyl-CoA = 1,3-dihydroxy-N-methylacridone + 3 CO2 + 4 CoA + H2O

RHEA:22284 2 H(+) + H2O + N-carbamoylputrescine = CO2 + NH4(+) + putrescine

RHEA:22352 H(+) + L-lysine = cadaverine + CO2

RHEA:22988 3-oxopropanoate + CoA + NADP(+) = acetyl-CoA + CO2 + NADPH

RHEA:23072 H(+) + oxaloacetate + phosphate = CO2 + H2O + phosphoenolpyruvate

RHEA:23112 6-methylsalicylate + H(+) = 3-methylphenol + CO2

RHEA:23916 H(+) + UDP-alpha-D-glucuronate = CO2 + UDP-alpha-D-xylose

RHEA:24184 4,5-dihydroxyphthalate + H(+) = 3,4-dihydroxybenzoate + CO2

RHEA:24200 4-aminobenzoate + H(+) = aniline + CO2

RHEA:24730 anthranilate + H(+) = aniline + CO2

RHEA:25177 4-methyl-2-oxopentanoate + CoA + NAD(+) = 3-methylbutanoyl-CoA + CO2 + NADH

RHEA:27758 (6S)-5,6,7,8-tetrahydrofolate + glycine + NAD(+) = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + CO2 + NADH + NH4(+)

RHEA:27786 2-oxoglutarate + CoA + NAD(+) = CO2 + NADH + succinyl-CoA

RHEA:28042 CoA + NAD(+) + pyruvate = acetyl-CoA + CO2 + NADH

RHEA:29167 H2O + pyruvate + ubiquinone-8 = acetate + CO2 + ubiquinol-8

RHEA:30035 3,4-dihydroxybenzoate + 2 H(+) + NADH + O2 = benzene-1,2,4-triol + CO2 + H2O + NAD(+)

RHEA:30039 3,4-dihydroxybenzoate + 2 H(+) + NADPH + O2 = benzene-1,2,4-triol + CO2 + H2O + NADP(+)

RHEA:30651 2 H2O + O2 + urate = allantoin + CO2 + H2O2

RHEA:30795 2-oxoadipate + CoA + NAD(+) = CO2 + glutaryl-CoA + NADH

RHEA:30847 FAD + glutaryl-CoA + 2 H(+) = (2E)-butenoyl-CoA + CO2 + FADH2

RHEA:31047 (S)-methylmalonate semialdehyde + CoA + NAD(+) = CO2 + NADH + propanoyl-CoA

RHEA:33211 1,4-dihydroxy-2-naphthoate + all-trans-heptaprenyl diphosphate + H(+) = 2-demethylmenaquinol-7 + CO2 + diphosphate

RHEA:33223 2-oxobutanoate + CoA + NAD(+) = CO2 + NADH + propanoyl-CoA

RHEA:34595 H(+) + isopentadecanoyl-CoA + L-serine = 3-dehydro-15-methylhexadecasphinganine + CO2 + CoA

RHEA:38547 anthraniloyl-CoA + H(+) + malonyl-CoA = 4-hydroxy-2(1H)-quinolone + CO2 + 2 CoA

RHEA:42508 6-acetamido-2-oxohexanoate + H2O + NAD(+) = 5-acetamidopentanoate + CO2 + H(+) + NADH

RHEA:43004 H(+) + O-carbamoyl-L-serine = 2-aminoprop-2-enoate + CO2 + NH4(+)

RHEA:44448 an acyl-CoA + H(+) + malonyl-[ACP] = a 3-oxoacyl-[ACP] + CO2 + CoA

RHEA:44800 1,4-dihydroxy-2-naphthoate + all-trans-hexaprenyl diphosphate + H(+) = 2-demethylmenaquinol-6 + CO2 + diphosphate

RHEA:44804 1,4-dihydroxy-2-naphthoate + all-trans-nonaprenyl diphosphate + H(+) = 2-demethylmenaquinol-9 + CO2 + diphosphate

RHEA:44808 1,4-dihydroxy-2-naphthoate + all-trans-decaprenyl diphosphate + H(+) = 2-demethylmenaquinol-10 + CO2 + diphosphate

RHEA:44812 1,4-dihydroxy-2-naphthoate + all-trans-undecaprenyl diphosphate + H(+) = 2-demethylmenaquinol-11 + CO2 + diphosphate

RHEA:44816 1,4-dihydroxy-2-naphthoate + all-trans-dodecaprenyl diphosphate + H(+) = 2-demethylmenaquinol-12 + CO2 + diphosphate

RHEA:44820 1,4-dihydroxy-2-naphthoate + all-trans-tridecaprenyl diphosphate + H(+) = 2-demethylmenaquinol-13 + CO2 + diphosphate

RHEA:50252 an acyl-CoA + H(+) + malonyl-CoA = a 3-oxoacyl-CoA + CO2 + CoA

RHEA:11084 3-dehydro-L-gulonate + H(+) = CO2 + L-xylulose

RHEA:11704 2 H(+) + N-(carboxyaminomethyl)urea = CO2 + N-(aminomethyl)urea

RHEA:11940 2 H(+) + H2O + L-citrulline = CO2 + L-ornithine + NH4(+)

RHEA:13153 (R)-glycerate + CO2 + NAD(+) = 2-hydroxy-3-oxosuccinate + 2 H(+) + NADH

RHEA:13157 (R)-glycerate + CO2 + NADP(+) = 2-hydroxy-3-oxosuccinate + 2 H(+) + NADPH

RHEA:13293 3 H(+) + malonyl-CoA + 2 NADPH + octadecanoyl-CoA = CO2 + CoA + eicosanoyl-CoA + H2O + 2 NADP(+)

RHEA:13297 3 H(+) + malonyl-CoA + 2 NADH + octadecanoyl-CoA = CO2 + CoA + eicosanoyl-CoA + H2O + 2 NAD(+)

RHEA:13321 (R)-3,3-dimethylmalate + NAD(+) = 3-methyl-2-oxobutanoate + CO2 + NADH

RHEA:14365 2 H(+) + H2O + N-carbamoyl-L-aspartate = CO2 + L-aspartate + NH4(+)

RHEA:15445 H(+) + H2O + O-carbamoyl-L-serine = CO2 + 2 NH4(+) + pyruvate

RHEA:16733 H(+) + orsellinate = CO2 + orcinol

RHEA:16793 H(+) + N-[(R)-4-phosphopantothenoyl]-L-cysteine = CO2 + D-pantetheine 4'-phosphate

RHEA:17733 acetylenedicarboxylate + H(+) + H2O = CO2 + pyruvate

RHEA:17785 H(+) + L-glutamate = 4-aminobutanoate + CO2

RHEA:18385 acetone + ATP + CO2 + 2 H2O = acetoacetate + AMP + 3 H(+) + 2 phosphate

RHEA:18901 H(+) + H2O + N-benzyloxycarbonyl-L-leucine = benzyl alcohol + CO2 + L-leucine

RHEA:19725 H(+) + UDP-alpha-D-galacturonate = CO2 + UDP-beta-L-arabinopyranose

RHEA:19729 acetoacetate + H(+) = acetone + CO2

RHEA:20900 H(+) + H2O + N-benzyloxycarbonylglycine = benzyl alcohol + CO2 + glycine

RHEA:21640 NADP(+) + prephenate = 3-(4-hydroxyphenyl)pyruvate + CO2 + NADPH

RHEA:22964 H(+) + L-ornithine = CO2 + putrescine

RHEA:23960 H(+) + 2 H2O2 + hexadecanoate = CO2 + 3 H2O + pentadecanal

RHEA:35815 4-aminobenzoate + 5-phospho-alpha-D-ribose 1-diphosphate + H(+) = 4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate + CO2 + diphosphate

RHEA:38531 3-oxodecanoate + anthraniloyl-CoA + H(+) = 2-heptyl-4-quinolone + CO2 + CoA + H2O

RHEA:54276 2-oxoglutarate + L-aspartyl-[protein] + O2 = (3S)-3-hydroxy-L-aspartyl-[protein] + CO2 + succinate

RHEA:56744 2-oxoglutarate + L-arginyl-[protein] + O2 = (3R)-3-hydroxy-L-arginyl-[protein] + CO2 + succinate

RHEA:11072 anthranilate + 3 H(+) + NADPH + O2 = catechol + CO2 + NADP(+) + NH4(+)

RHEA:11076 anthranilate + 3 H(+) + NADH + O2 = catechol + CO2 + NAD(+) + NH4(+)

RHEA:12797 (6S)-6-hydroxyhyoscyamine + 2-oxoglutarate + O2 = CO2 + H(+) + H2O + scopolamine + succinate

RHEA:13869 NAD(+) + prephenate = 3-(4-hydroxyphenyl)pyruvate + CO2 + NADH

RHEA:13997 3-methyl-2-oxobutanoate + CoA + NAD(+) = 2-methylpropanoyl-CoA + CO2 + NADH

RHEA:14601 L-lysine + O2 = 5-aminopentanamide + CO2 + H2O

RHEA:15929 2 H(+) + 2 H2O + methylenediurea = CO2 + N-(hydroxymethyl)urea + 2 NH4(+)

RHEA:17197 2 3-(4-hydroxyphenyl)pyruvate + O2 = 2 4-hydroxyphenylacetate + 2 CO2

RHEA:21520 2 [Fe(III)-cytochrome b1] + formate = 2 [Fe(II)-cytochrome b1] + CO2 + H(+)

RHEA:30907 (S)-3-methyl-2-oxopentanoate + CoA + NAD(+) = 2-methylbutanoyl-CoA + CO2 + NADH

RHEA:40747 2-oxoglutarate + L-lysine + O2 = (3S)-3-hydroxy-L-lysine + CO2 + succinate

RHEA:40931 2-oxoglutarate + L-ornithine + O2 = (3S)-3-hydroxy-L-ornithine + CO2 + succinate

RHEA:42420 2-oxoglutarate + L-lysine + O2 = (4R)-4-hydroxy-L-lysine + CO2 + succinate

RHEA:45484 H(+) + pyruvate = acetaldehyde + CO2

RHEA:10388 GTP + oxaloacetate = CO2 + GDP + phosphoenolpyruvate

RHEA:10548 L-arginine + O2 = 4-guanidinobutanamide + CO2 + H2O

RHEA:10732 ATP + firefly D-luciferin + O2 = AMP + CO2 + diphosphate + firefly oxyluciferin + hnu

RHEA:13317 (2R,3R)-tartrate + H(+) = (R)-glycerate + CO2

RHEA:20513 2-aryl-2-methylmalonate + H(+) = 2-arylpropionate + CO2

RHEA:20948 3-sulfopyruvate + H(+) = CO2 + sulfoacetaldehyde

RHEA:21372 H(+) + H2O + urethane = CO2 + ethanol + NH4(+)

RHEA:21400 2-oxoglutarate + CoA + NADP(+) = CO2 + NADPH + succinyl-CoA

RHEA:25221 H(+) + L-cysteate = CO2 + taurine

RHEA:27413 2-oxoglutarate + codeine + O2 = CO2 + formaldehyde + morphine + succinate

RHEA:27477 2-oxoglutarate + O2 + thebaine = CO2 + formaldehyde + neopinone + succinate

RHEA:29063 a menaquinone + formate + H(+) = a menaquinol + CO2

RHEA:31015 H(+) + indole-3-carboxylate = CO2 + indole

RHEA:32755 (S)-naringenin + 2-oxoglutarate + O2 = apigenin + CO2 + H(+) + H2O + succinate

RHEA:34839 4 H(+) + 5 malonyl-CoA = 5,7-dihydroxy-2-methyl-4H-chromen-4-one + 5 CO2 + 5 CoA + H2O

RHEA:35119 (4-coumaroyl)acetyl-CoA + 4-coumaroyl-CoA + H2O = bisdemethoxycurcumin + CO2 + 2 CoA

RHEA:35139 (E)-4-coumaroyl-CoA + H2O + trans-feruloylacetyl-CoA = CO2 + 2 CoA + demethoxycurcumin

RHEA:35831 2-oxoglutarate + kanamycin B + O2 = 2'-dehydrokanamycin A + CO2 + NH4(+) + succinate

RHEA:37007 (8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA + H(+) + malonyl-CoA = 3-oxo-(10Z,13Z,16Z,19Z)-docosatetraenoyl-CoA + CO2 + CoA

RHEA:37095 (10Z,13Z,16Z,19Z)-docosatetraenoyl-CoA + H(+) + malonyl-CoA = 3-oxo-(12Z,15Z,18Z,21Z)-tetracosatetraenoyl-CoA + CO2 + CoA

RHEA:38031 (3E,5R)-5-carboxy-2-oxohept-3-enedioate + H(+) = (2Z,4Z)-2-hydroxyhepta-2,4-diene-1,7-dioate + CO2

RHEA:41440 (2-aminoethyl)phosphonate + 2-oxoglutarate + O2 = (2R)-(2-amino-1-hydroxyethyl)phosphonate + CO2 + succinate

RHEA:46952 2 formate + NAD(+) + 2 oxidized [2Fe-2S]-[ferredoxin] = 2 CO2 + H(+) + NADH + 2 reduced [2Fe-2S]-[ferredoxin]

RHEA:48752 2-oxoglutarate + O2 + validamycin A = CO2 + H(+) + succinate + validamycin B

RHEA:55648 2-oxoglutarate + O2 + validoxylamine A = CO2 + H(+) + succinate + validoxylamine B

RHEA:59216 (indol-3-yl)acetate + H(+) = CO2 + skatole

RHEA:10524 2-oxoglutarate + H(+) = CO2 + succinate semialdehyde

RHEA:10584 4-coumaroyl-CoA + 3 H(+) + 3 malonyl-CoA + NADPH = 3 CO2 + 4 CoA + H2O + isoliquiritigenin + NADP(+)

RHEA:11004 2 H(+) + NADH + O2 + salicylate = catechol + CO2 + H2O + NAD(+)

RHEA:11052 4-aminobenzoate + 2 H(+) + NADH + O2 = 4-aminophenol + CO2 + H2O + NAD(+)

RHEA:11056 4-aminobenzoate + 2 H(+) + NADPH + O2 = 4-aminophenol + CO2 + H2O + NADP(+)

RHEA:11628 a 2-oxocarboxylate + H(+) = an aldehyde + CO2

RHEA:11900 (1R,2S)-homoisocitrate + NAD(+) = 2-oxoadipate + CO2 + NADH

RHEA:11936 4-coumaroyl-CoA + 3 H(+) + 3 malonyl-CoA = 4 CO2 + 4 CoA + trans-resveratrol

RHEA:12188 2-oxoglutarate + [dihydrolipoyllysine-residue succinyltransferase]-(R)-N(6)-lipoyl-L-lysine + H(+) = [dihydrolipoyllysine-residue succinyltransferase]-(R)-N(6)-(S(8)-succinyldihydrolipoyl)-L-lysine + CO2

RHEA:12653 (S)-malate + NAD(+) = CO2 + NADH + pyruvate

RHEA:12677 AH2 + Latia luciferin + 2 O2 = A + CO2 + formate + H(+) + H2O + hnu + oxidized Latia luciferin

RHEA:13593 allantoate + 2 H(+) + H2O = CO2 + NH4(+) + ureidoglycine

RHEA:13669 5-hydroxy-6-methylpyridine-3,4-dicarboxylate + H(+) = 3-hydroxy-2-methylpyridine-5-carboxylate + CO2

RHEA:13821 2-oxoglutarate + glutarate + O2 = (S)-2-hydroxyglutarate + CO2 + succinate

RHEA:15657 1,6-dihydroxy-2-methylcyclohexa-2,4-dienecarboxylate + NAD(+) = 3-methylcatechol + CO2 + NADH

RHEA:15833 (S)-4-hydroxymandelate + H(+) + O2 = 4-hydroxybenzaldehyde + CO2 + H2O2

RHEA:15909 2-oxoglutarate + O2 + taurine = aminoacetaldehyde + CO2 + H(+) + succinate + sulfite

RHEA:16033 2-oxoglutarate + gibberellin A44 + O2 = CO2 + gibberellin A19 + H(+) + succinate

RHEA:16165 L-tryptophan + O2 = CO2 + H2O + indole-3-acetamide

RHEA:16385 4-hydroxybenzoate + 2 H(+) + NADPH + O2 = CO2 + H2O + hydroquinone + NADP(+)

RHEA:16389 4-hydroxybenzoate + 2 H(+) + NADH + O2 = CO2 + H2O + hydroquinone + NAD(+)

RHEA:16513 (S)-lactate + O2 = acetate + CO2 + H2O

RHEA:17641 H(+) + L-arginine = agmatine + CO2

RHEA:18253 (S)-malate + NADP(+) = CO2 + NADPH + pyruvate

RHEA:18533 5-hydroxy-L-tryptophan + H(+) = CO2 + serotonin

RHEA:18601 3,4-dihydroxyphthalate + H(+) = 3,4-dihydroxybenzoate + CO2

RHEA:18969 a long-chain fatty acid + H(+) + hnu = a long-chain alkane + CO2

RHEA:19533 2 H(+) + 2 H2O + N(2)-succinyl-L-arginine = CO2 + N(2)-succinyl-L-ornithine + 2 NH4(+)

RHEA:19717 H(+) + L-phenylalanine = 2-phenylethylamine + CO2

RHEA:21348 8 H(+) + 10 malonyl-CoA = 10 CO2 + 10 CoA + 2 H2O + tetracenomycin F2

RHEA:21580 (2S)-2-acetolactate + H(+) = (R)-acetoin + CO2

RHEA:22356 diphosphate + oxaloacetate = CO2 + phosphate + phosphoenolpyruvate

RHEA:22416 3,4-dihydroxybenzoate + H(+) = catechol + CO2

RHEA:22760 Cypridina luciferin + O2 = CO2 + hnu + oxidized Cypridina luciferin

RHEA:22992 3-oxopropanoate + CoA + NAD(+) = acetyl-CoA + CO2 + NADH

RHEA:23316 2'-deoxyuridine + 2-oxoglutarate + O2 = 2-deoxy-D-ribono-1,4-lactone + CO2 + succinate + uracil

RHEA:24224 (1R,6S)-1,6-dihydroxy-4-methylcyclohexa-2,4-diene-1-carboxylate + NADP(+) = 4-methylcatechol + CO2 + NADPH

RHEA:24228 (1R,6S)-1,6-dihydroxy-4-methylcyclohexa-2,4-diene-1-carboxylate + NAD(+) = 4-methylcatechol + CO2 + NADH

RHEA:24780 C-13(2)-carboxypyropheophorbide a + H(+) = CO2 + pyropheophorbide a

RHEA:25013 H(+) + N,N-dihydroxy-L-tryptophan = (E)-(indol-3-yl)acetaldehyde oxime + CO2 + H2O

RHEA:25078 (2S)-2-isopropyl-3-oxosuccinate + H(+) = 4-methyl-2-oxopentanoate + CO2

RHEA:25653 (2S)-2-amino-3-oxobutanoate + H(+) = aminoacetone + CO2

RHEA:25772 2-oxoglutarate + L-asparagine + O2 = (2S,3S)-3-hydroxyasparagine + CO2 + succinate

RHEA:27485 allantoate + 2 H(+) + H2O = (S)-2-ureidoglycine + CO2 + NH4(+)

RHEA:27746 H(+) + L-cysteine = CO2 + cysteamine

RHEA:27778 4-hydroxy-3-all-trans-octaprenylbenzoate + H(+) = 2-all-trans-octaprenylphenol + CO2

RHEA:28250 acetyl-CoA + H(+) + malonyl-CoA = acetoacetyl-CoA + CO2 + CoA

RHEA:29075 formate(out) + 2 H(+)(in) + ubiquinone-8 = CO2(out) + H(+)(out) + ubiquinol-8

RHEA:30703 H(+) + salicylate = CO2 + phenol

RHEA:31375 H(+) + pyrrole-2-carboxylate = 1H-pyrrole + CO2

RHEA:32115 2-oxoglutarate + DIBOA beta-D-glucoside + O2 = CO2 + succinate + TRIBOA beta-D-glucoside

RHEA:32127 2-oxoglutarate + L-proline + O2 = cis-4-hydroxy-L-proline + CO2 + succinate

RHEA:32135 2-oxobutanoate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] = CO2 + H(+) + propanoyl-CoA + 2 reduced [2Fe-2S]-[ferredoxin]

RHEA:32279 allantoate + 2 H(+) + 2 H2O = (S)-ureidoglycolate + CO2 + 2 NH4(+)

RHEA:32715 (2R,3S)-3-methylmalate + NAD(+) = 2-oxobutanoate + CO2 + NADH

RHEA:33447 4alpha-carboxyl-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol + NADP(+) = 4alpha-methyl-5alpha-cholesta-8,24-dien-3-one + CO2 + NADPH

RHEA:33683 H(+) + L-serine + octadecanoyl-CoA = 3-oxoeicosasphinganine + CO2 + CoA

RHEA:34107 glycine + H(+) + hexadecanoyl-CoA = 1-deoxymethyl-3-dehydrosphinganine + CO2 + CoA

RHEA:34139 Delta(9)-tetrahydrocannabinolate + H(+) = CO2 + Delta(9)-tetrahydrocannabinol

RHEA:34175 2-hydroxybenzoyl-CoA + malonyl-CoA = 4-hydroxycoumarin + CO2 + 2 CoA

RHEA:34579 2 2-oxoglutarate + 2 O2 + pentalenolactone D = 2 CO2 + H2O + pentalenolactone F + 2 succinate

RHEA:34583 2-oxoglutarate + O2 + pentalenolactone D = CO2 + H2O + pentalenolactone E + succinate

RHEA:34587 2-oxoglutarate + O2 + pentalenolactone E = CO2 + pentalenolactone F + succinate

RHEA:35115 4-coumaroyl-CoA + H(+) + malonyl-CoA = (4-coumaroyl)acetyl-CoA + CO2 + CoA

RHEA:35319 H(+) + malonyl-CoA + octadecanoyl-CoA = 3-oxoeicosanoyl-CoA + CO2 + CoA

RHEA:35383 precorrin-6B + S-adenosyl-L-methionine = CO2 + H(+) + precorrin-7 + S-adenosyl-L-homocysteine

RHEA:35975 2-oxoglutarate + AH2 + fumitremorgin B + 2 O2 = A + CO2 + H2O + succinate + verruculogen

RHEA:36031 (S)-2-ureidoglycine + allantoate + 2 H(+) + 2 H2O = (S)-ureidoglycolate + CO2 + 2 NH4(+) + ureidoglycine

RHEA:36519 H(+) + hexacosanoyl-CoA + malonyl-CoA = 3-oxooctacosanyol-CoA + CO2 + CoA

RHEA:36527 (11Z)-eicosenoyl-CoA + H(+) + malonyl-CoA = (13Z)-3-oxodocosenoyl-CoA + CO2 + CoA

RHEA:36531 (13Z)-docosenoyl-CoA + H(+) + malonyl-CoA = (15Z)-3-oxotetracosenoyl-CoA + CO2 + CoA

RHEA:36819 (11Z,14Z,17Z,20Z,23Z)-hexacosapentaenoyl-CoA + H(+) + malonyl-CoA = 3-oxo-(13Z,16Z,19Z,22Z,25Z)-octacosapentaenoyl-CoA + CO2 + CoA

RHEA:36843 (13Z,16Z,19Z,22Z,25Z)-octacosapentaenoyl-CoA + H(+) + malonyl-CoA = 3-oxo-(15Z,18Z,21Z,24Z,27Z)-triacontapentaenoyl-CoA + CO2 + CoA

RHEA:36851 (15Z,18Z,21Z,24Z,27Z)-triacontapentaenoyl-CoA + H(+) + malonyl-CoA = 3-oxo-(17Z,20Z,23Z,26Z,29Z)-dotriacontapentaenoyl-CoA + CO2 + CoA

RHEA:36871 (19Z,22Z,25Z,28Z,31Z)-tetratriacontapentaenoyl-CoA + H(+) + malonyl-CoA = 3-oxo-(21Z,24Z,27Z,30Z,33Z)-hexatriacontapentaenoyl-CoA + CO2 + CoA

RHEA:36875 (21Z,24Z,27Z,30Z,33Z)-hexatriacontapentaenoyl-CoA + H(+) + malonyl-CoA = 3-oxo-(23Z,26Z,29Z,32Z,35Z)-octatriacontapentaenoyl-CoA + CO2 + CoA

RHEA:36907 (11Z,14Z,17Z,20Z)-hexacosatetraenoyl-CoA + H(+) + malonyl-CoA = (13Z,16Z,19Z,22Z)-3-oxooctacosatetraenoyl-CoA + CO2 + CoA

RHEA:36911 (13Z,16Z,19Z,22Z)-octacosatetraenoyl-CoA + H(+) + malonyl-CoA = 3-oxo-(15Z,18Z,21Z,24Z)-triacontatetraenoyl-CoA + CO2 + CoA

RHEA:36915 (15Z,18Z,21Z,24Z)-triacontatetraenoyl-CoA + H(+) + malonyl-CoA = 3-oxo-(17Z,20Z,23Z,26Z)-dotriacontatetraenoyl-CoA + CO2 + CoA

RHEA:36919 (17Z,20Z,23Z,26Z)-dotriacontatetraenoyl-CoA + H(+) + malonyl-CoA = 3-oxo-(19Z,22Z,25Z,28Z)-tetratriacontatetraenoyl-CoA + CO2 + CoA

RHEA:36923 (19Z,22Z,25Z,28Z)-tetratriacontatetraenoyl-CoA + H(+) + malonyl-CoA = 3-oxo-(21Z,24Z,27Z,30Z)-hexatriacontatetraenoyl-CoA + CO2 + CoA

RHEA:36927 (21Z,24Z,27Z,30Z)-hexatriacontatetraenoyl-CoA + H(+) + malonyl-CoA = 3-oxo-(23Z,26Z,29Z,32Z)-octatriacontatetraenoyl-CoA + CO2 + CoA

RHEA:36943 (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + H(+) + malonyl-CoA = 3-oxo-(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + CO2 + CoA

RHEA:36947 (6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + H(+) + malonyl-CoA = 3-oxo-(8Z,11Z,14Z,17Z,20Z,23Z)-hexacosahexaenoyl-CoA + CO2 + CoA

RHEA:36963 (8Z,11Z,14Z,17Z,20Z,23Z)-hexacosahexaenoyl-CoA + H(+) + malonyl-CoA = 3-oxo-(10Z,13Z,16Z,19Z,22Z,25Z)-octacosahexaenoyl-CoA + CO2 + CoA

RHEA:36979 (12Z,15Z,18Z,21Z,24Z,27Z)-triacontahexaenoyl-CoA + H(+) + malonyl-CoA = 3-oxo-(14Z,17Z,20Z,23Z,26Z,29Z)-dotriacontahexaenoyl-CoA + CO2 + CoA

RHEA:36983 (14Z,17Z,20Z,23Z,26Z,29Z)-dotriacontahexaenoyl-CoA + H(+) + malonyl-CoA = 3-oxo-(16Z,19Z,22Z,25Z,28Z,31Z)-tetratriacontahexaenoyl-CoA + CO2 + CoA

RHEA:36995 (16Z,19Z,22Z,25Z,28Z,31Z)-tetratriacontahexaenoyl-CoA + H(+) + malonyl-CoA = 3-oxo-(18Z,21Z,24Z,27Z,30Z,33Z)-hexatriacontahexaenoyl-CoA + CO2 + CoA

RHEA:39291 (9Z,12Z,15Z,18Z)-tetracosatetraenoyl-CoA + H(+) + malonyl-CoA = 3-oxo-(11Z,14Z,17Z,20Z)-hexacosatetraenoyl-CoA + CO2 + CoA

RHEA:41448 2-oxoglutarate + L-isoleucine + O2 = (4S)-4-hydroxy-L-isoleucine + CO2 + succinate

RHEA:42244 H(+) + malonyl-[ACP] + propanoyl-CoA = 3-oxopentanoyl-[ACP] + CO2 + CoA

RHEA:42248 butanoyl-CoA + H(+) + malonyl-[ACP] = 3-oxohexanoyl-[ACP] + CO2 + CoA

RHEA:42252 H(+) + malonyl-[ACP] + pentanoyl-CoA = 3-oxoheptanoyl-[ACP] + CO2 + CoA

RHEA:42260 H(+) + heptanoyl-CoA + malonyl-[ACP] = 3-oxononanoyl-[ACP] + CO2 + CoA

RHEA:42268 2-methylpropanoyl-CoA + H(+) + malonyl-[ACP] = 3-oxo-4-methylpentanoyl-[ACP] + CO2 + CoA

RHEA:42272 3-methylbutanoyl-CoA + H(+) + malonyl-[ACP] = 3-oxo-5-methylhexanoyl-[ACP] + CO2 + CoA

RHEA:42276 2-methylbutanoyl-CoA + H(+) + malonyl-[ACP] = 3-oxo-4-methylhexanoyl-[ACP] + CO2 + CoA

RHEA:42836 acetyl-CoA + 7 H(+) + 5 malonyl-CoA + 3 NADPH = 5-methyl-1-naphthoate + 5 CO2 + 6 CoA + 4 H2O + 3 NADP(+)

RHEA:42840 acetyl-CoA + 6 H(+) + 5 malonyl-CoA + 2 NADPH = 2-hydroxy-5-methyl-1-naphthoate + 5 CO2 + 6 CoA + 3 H2O + 2 NADP(+)

RHEA:43524 L-allo-threonine + NADP(+) = aminoacetone + CO2 + NADPH

RHEA:43620 L-serine + NADP(+) = aminoacetaldehyde + CO2 + NADPH

RHEA:43624 2-aminomalonate semialdehyde + H(+) = aminoacetaldehyde + CO2

RHEA:43628 L-serine + NAD(+) = aminoacetaldehyde + CO2 + NADH

RHEA:43852 H(+) + malonyl-CoA + triacontanoyl-CoA = 3-oxo-dotriacontanoyl-CoA + CO2 + CoA

RHEA:44140 CoA + 2 H(+) + oxidized [flavodoxin] + pyruvate = acetyl-CoA + CO2 + reduced [flavodoxin]

RHEA:44264 eicosanoyl-CoA + 2 H(+) + 2 malonyl-CoA = 4-hydroxy-6-nonadecylpyran-2-one + 2 CO2 + 3 CoA

RHEA:44276 eicosanoyl-CoA + 3 H(+) + 3 malonyl-CoA = 4-hydroxy-6-(2-oxohenicosyl)pyran-2-one + 3 CO2 + 4 CoA

RHEA:44284 2 H(+) + 2 malonyl-CoA + octanoyl-CoA = 4-hydroxy-6-heptylpyran-2-one + 2 CO2 + 3 CoA

RHEA:44296 2 H(+) + hexadecanoyl-CoA + malonyl-CoA + methylmalonyl-CoA = 4-hydroxy-5-methyl-6-pentadecylpyran-2-one + 2 CO2 + 3 CoA

RHEA:44300 2 H(+) + malonyl-CoA + methylmalonyl-CoA + octadecanoyl-CoA = 4-hydroxy-5-methyl-6-heptadecylpyran-2-one + 2 CO2 + 3 CoA

RHEA:44568 4-hydroxy-3-all-trans-hexaprenylbenzoate + H(+) = 2-all-trans-hexaprenylphenol + CO2

RHEA:44572 4-hydroxy-3-all-trans-heptaprenylbenzoate + H(+) = 2-all-trans-heptaprenylphenol + CO2

RHEA:44576 4-hydroxy-3-all-trans-nonaprenylbenzoate + H(+) = 2-all-trans-nonaprenylphenol + CO2

RHEA:44580 4-hydroxy-3-all-trans-decaprenylbenzoate + H(+) = 2-all-trans-decaprenylphenol + CO2

RHEA:45160 3-oxopropanoate + H(+) = acetaldehyde + CO2

RHEA:45824 H(+) + L-serine = CO2 + ethanolamine

RHEA:45856 3-hydroxytetradecanoyl-CoA + 2 H(+) + 2 malonyl-CoA = 4-hydroxy-6-(2-hydroxytridecyl)-pyran-2-one + 2 CO2 + 3 CoA

RHEA:45860 12-hydroxyoctadecanoyl-CoA + 2 H(+) + 2 malonyl-CoA = 4-hydroxy-6-(11-hydroxyheptadecyl)-pyran-2-one + 2 CO2 + 3 CoA

RHEA:45864 16-hydroxyhexadecanoyl-CoA + 2 H(+) + 2 malonyl-CoA = 4-hydroxy-6-(15-hydroxypentadecyl)-pyran-2-one + 2 CO2 + 3 CoA

RHEA:45868 9-decenoyl-CoA + 2 H(+) + 2 malonyl-CoA = 4-hydroxy-6-(non-8-en-1-yl)-pyran-2-one + 2 CO2 + 3 CoA

RHEA:45872 15-hydroxypentadecanoyl-CoA + 2 H(+) + 2 malonyl-CoA = 4-hydroxy-6-(14-hydroxytetradecyl)-pyran-2-one + 2 CO2 + 3 CoA

RHEA:45876 2-methylhexadecanoyl-CoA + 2 H(+) + 2 malonyl-CoA = 6-(hexadecan-2-yl)-4-hydroxy-pyran-2-one + 2 CO2 + 3 CoA

RHEA:45880 3-methylundecanoyl-CoA + 2 H(+) + 2 malonyl-CoA = 4-hydroxy-6-(2-methyldecyl)-pyran-2-one + 2 CO2 + 3 CoA

RHEA:45884 12-methyloctadecanoyl-CoA + 2 H(+) + 2 malonyl-CoA = 4-hydroxy-6-(11-methylheptadecyl)-pyran-2-one + 2 CO2 + 3 CoA

RHEA:45888 12-methyltridecanoyl-CoA + 2 H(+) + 2 malonyl-CoA = 4-hydroxy-6-(11-methyldodecyl)-pyran-2-one + 2 CO2 + 3 CoA

RHEA:45916 12-hydroxyoctadecanoyl-CoA + 3 H(+) + 3 malonyl-CoA = 4-hydroxy-6-(13-hydroxy-2-oxononadecyl)pyran-2-one + 3 CO2 + 4 CoA

RHEA:45920 16-hydroxyhexadecanoyl-CoA + 3 H(+) + 3 malonyl-CoA = 4-hydroxy-6-(17-hydroxy-2-oxoheptadecyl)pyran-2-one + 3 CO2 + 4 CoA

RHEA:45924 9-decenoyl-CoA + 3 H(+) + 3 malonyl-CoA = 4-hydroxy-6-(2-oxoundec-10-en-1-yl)pyran-2-one + 3 CO2 + 4 CoA

RHEA:45928 15-hydroxypentadecanoyl-CoA + 3 H(+) + 3 malonyl-CoA = 4-hydroxy-6-(16-hydroxy-2-oxohexadecyl)pyran-2-one + 3 CO2 + 4 CoA

RHEA:45932 2-methylhexadecanoyl-CoA + 3 H(+) + 3 malonyl-CoA = 4-hydroxy-6-(3-methyl-2-oxoheptadecyl)pyran-2-one + 3 CO2 + 4 CoA

RHEA:45936 3-methylundecanoyl-CoA + 3 H(+) + 3 malonyl-CoA = 4-hydroxy-6-(4-methyl-2-oxododecyl)pyran-2-one + 3 CO2 + 4 CoA

RHEA:45940 12-methyloctadecanoyl-CoA + 3 H(+) + 3 malonyl-CoA = 4-hydroxy-6-(13-methyl-2-oxononadecyl)pyran-2-one + 3 CO2 + 4 CoA

RHEA:45944 12-methyltridecanoyl-CoA + 3 H(+) + 3 malonyl-CoA = 4-hydroxy-6-(13-methyl-2-oxotetradecyl)pyran-2-one + 3 CO2 + 4 CoA

RHEA:46828 4alpha-carboxy-4beta-methyl-5alpha-cholest-8-en-3beta-ol + NADP(+) = 4alpha-methyl-5alpha-cholest-8-en-3-one + CO2 + NADPH

RHEA:46848 4alpha-carboxy-5alpha-cholest-8-ene-3beta-ol + NADP(+) = 5alpha-cholest-8-en-3-one + CO2 + NADPH

RHEA:47608 3-(3-hydroxyphenyl)-propanoyl-CoA + 3 H(+) + 3 malonyl-CoA = 3,3',5-trihydroxybibenzyl + 4 CO2 + 4 CoA

RHEA:48744 (-)-yatein + 2-oxoglutarate + O2 = (-)-deoxypodophyllotoxin + CO2 + H2O + succinate

RHEA:49184 chlorophyllide a + H(+) + H2O = 8-ethyl-12-methyl-3-vinylbacteriochlorophyllide d + CO2 + methanol

RHEA:49904 (1R,6R)-1,4,5,5a,6,9-hexahydrophenazine-1,6-dicarboxylate + H(+) + O2 = (1R,10aS)-1,4,10,10a-tetrahydrophenazine-1-carboxylate + CO2 + H2O2

RHEA:49960 (1R)-1,4,5,10-tetrahydrophenazine-1-carboxylate + H(+) + O2 = 5,10-dihydrophenazine + CO2 + H2O2

RHEA:50380 3 H(+) + 3 malonyl-CoA = 1,3,5-trihydroxybenzene + 3 CO2 + 3 CoA

RHEA:51528 4-hydroxy-3-methoxybenzoate + H(+) = CO2 + guaiacol

RHEA:52908 3-dimethylallyl-4-hydroxyphenylpyruvate + O2 = 3-dimethylallyl-4-hydroxymandelate + CO2

RHEA:52912 3-dimethylallyl-4-hydroxymandelate + O2 = 3-dimethylallyl-4-hydroxybenzoate + CO2 + H2O

RHEA:53828 2-oxoglutarate + a 5-hydroxymethyl-2'-deoxycytidine in DNA + O2 = a 5-formyl-2'-deoxycytidine in DNA + CO2 + H2O + succinate

RHEA:53832 2-oxoglutarate + a 5-formyl-2'-deoxycytidine in DNA + O2 = a 5-carboxyl-2'-deoxycytidine in DNA + CO2 + H(+) + succinate

RHEA:54024 2-oxoglutarate + L-histidyl-[ribosomal protein uL15] + O2 = (3S)-3-hydroxy-L-histidyl-[ribosomal protein uL15] + CO2 + succinate

RHEA:54264 2-oxoglutarate + L-histidyl-[ankyrin-repeat domain protein] + O2 = (3S)-3-hydroxy-L-histidyl-[ankyrin-repeat domain protein] + CO2 + succinate

RHEA:54356 3-methyl-2-oxobutanoate + H(+) = 2-methylpropanal + CO2

RHEA:54360 4-methyl-2-oxopentanoate + H(+) = 3-methylbutanal + CO2

RHEA:54368 acetaldehyde + H(+) + pyruvate = acetoin + CO2

RHEA:54436 2-oxoglutarate + a (2R,3S,4S)-leucoanthocyanidin + O2 = a (4S)-2,3-dehydroflavan-3,4-diol + CO2 + H(+) + H2O + succinate

RHEA:54524 acetoacetate + H(+) + methylglyoxal = 3-hydroxyhexane-2,5-dione + CO2

RHEA:54576 2-oxoglutarate + N(1)-methyladenosine in tRNA + O2 = adenosine in tRNA + CO2 + formaldehyde + succinate

RHEA:54596 2-oxoglutarate + hexadecanoyl-CoA + O2 = 2-hydroxyhexadecanoyl-CoA + CO2 + succinate

RHEA:54600 2-oxoglutarate + O2 + octanoyl-CoA = 2-hydroxyoctanoyl-CoA + CO2 + succinate

RHEA:54604 2-oxoglutarate + decanoyl-CoA + O2 = 2-hydroxydecanoyl-CoA + CO2 + succinate

RHEA:54612 2-oxoglutarate + 3-methylbutanoyl-CoA + O2 = 2-hydroxy-3-methylbutanoyl-CoA + CO2 + succinate

RHEA:54616 2-oxoglutarate + heptadecanoyl-CoA + O2 = 2-hydroxyheptadecanoyl-CoA + CO2 + succinate

RHEA:54620 2-oxoglutarate + eicosanoyl-CoA + O2 = 2-hydroxyeicosanoyl-CoA + CO2 + succinate

RHEA:54624 2-oxoglutarate + O2 + octadecanoyl-CoA = 2-hydroxyoctadecanoyl-CoA + CO2 + succinate

RHEA:54628 2-oxoglutarate + dodecanoyl-CoA + O2 = 2-hydroxydodecanoyl-CoA + CO2 + succinate

RHEA:54632 2-oxoglutarate + O2 + tetradecanoyl-CoA = 2-hydroxytetradecanoyl-CoA + CO2 + succinate

RHEA:55040 (9Z)-hexadecenoyl-[ACP] + H(+) + malonyl-[ACP] = 3-oxo-(11Z)-octadecenoyl-[ACP] + CO2 + holo-[ACP]

RHEA:55172 2-oxoglutarate + hexanoyl-CoA + O2 = 2-hydroxyhexanoyl-CoA + CO2 + succinate

RHEA:55176 2-oxoglutarate + butanoyl-CoA + O2 = 2-hydroxybutanoyl-CoA + CO2 + succinate

RHEA:55180 2-oxoglutarate + 3-methylnonanoyl-CoA + O2 = 2-hydroxy-3-methylnonanoyl-CoA + CO2 + succinate

RHEA:55184 2-oxoglutarate + 3-methylundecanoyl-CoA + O2 = 2-hydroxy-3-methylundecanoyl-CoA + CO2 + succinate

RHEA:55192 2-oxoglutarate + 3-methyldodecanoyl-CoA + O2 = 2-hydroxy-3-methyldodecanoyl-CoA + CO2 + succinate

RHEA:55532 H(+) + H2O + L-phenylalanine + O2 = 2-phenylacetaldehyde + CO2 + H2O2 + NH4(+)

RHEA:56060 H(+) + hexadecanoate + hnu = CO2 + pentadecane

RHEA:56500 (R)-3,5-bisphosphomevalonate + H(+) = CO2 + isopentenyl phosphate + phosphate

RHEA:56704 (2S)-3-(1H-indol-3-yl)-2-isocyanopropanoate + 2-oxoglutarate + H(+) + O2 = 3-[(E)-2-isocyanovinyl]indole + 2 CO2 + H2O + succinate

RHEA:56812 2-oxoglutarate + chloride + H(+) + L-threonyl-[L-threonyl-carrier protein] + O2 = 4-chloro-L-threonyl-[L-threonyl-carrier protein] + CO2 + H2O + succinate

RHEA:57052 3-oxo-isoapionate + H(+) = CO2 + L-erythrulose

RHEA:57072 3-oxo-isoapionate 4-phosphate + H(+) = CO2 + L-erythrulose 1-phosphate

RHEA:57152 2-oxoglutarate + L-lysyl-[protein] + O2 = (3S)-3-hydroxy-L-lysyl-[protein] + CO2 + succinate

RHEA:57156 2-oxoglutarate + L-lysyl-[protein] + O2 = 4-hydroxy-L-lysyl-[protein] + CO2 + succinate

RHEA:57160 2-oxoglutarate + L-arginyl-[ribosomal protein eS6] + O2 = (3R)-3-hydroxy-L-arginyl-[ribosomal protein eS6] + CO2 + succinate

RHEA:57164 2-oxoglutarate + L-arginyl-[RCC1 domain-containing protein] + O2 = (3R)-3-hydroxy-L-arginyl-[RCC1 domain-containing protein] + CO2 + succinate

RHEA:57728 H(+) + trans-aconitate = CO2 + itaconate

RHEA:57896 2-oxoglutarate + a 5'-(N(7)-methyl 5'-triphosphoguanosine)-(N(7),2'-O-dimethyladenosine 5'-phosphate)-[mRNA] + O2 = a 5'-(N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyladenosine 5'-phosphate)-[mRNA] + CO2 + formaldehyde + succinate

RHEA:57900 2-oxoglutarate + N(6)-methyladenosine in U6 snRNA + O2 = adenosine in U6 snRNA + CO2 + formaldehyde + succinate

RHEA:57904 2-oxoglutarate + a 5'-(N(7)-methyl 5'-triphosphoguanosine)-(N(7),2'-O-dimethyladenosine 5'-phosphate) in U6 snRNA + O2 = a 5'-(N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyladenosine 5'-phosphate) in U6 snRNA + CO2 + formaldehyde + succinate

RHEA:58784 2-oxoglutarate + a 5'-methyltriphosphate-guanosine-ribonucleotide-snRNA + O2 = a 5'-triphospho-guanosine-ribonucleotide-snRNA + CO2 + formaldehyde + H(+) + succinate

RHEA:59048 D-ornithine + H(+) = CO2 + putrescine

RHEA:59052 D-lysine + H(+) = cadaverine + CO2

RHEA:59120 2-[(L-alanin-3-ylcarbamoyl)methyl]-2-hydroxybutanedioate + H(+) = 2-[(2-aminoethylcarbamoyl)methyl]-2-hydroxybutanedioate + CO2

RHEA:59900 2-oxoglutarate + L-gamma-glutamyl-L-propargylglycine + O2 = CO2 + L-gamma-glutamyl-(3R)-L-beta-ethynylserine + succinate

RHEA:10316 2-oxoglutarate + O2 + thymine = 5-hydroxymethyluracil + CO2 + succinate

RHEA:10372 CoA + NAD(+) + phenylglyoxylate = benzoyl-CoA + CO2 + NADH

RHEA:10432 2-(acetamidomethylene)succinate + H(+) + 2 H2O = acetate + CO2 + NH4(+) + succinate semialdehyde

RHEA:10624 2 ATP + CO2 + H2O + NH4(+) = 2 ADP + carbamoyl phosphate + 3 H(+) + phosphate

RHEA:10876 4-hydroxybenzoate + H(+) = CO2 + phenol

RHEA:11000 an N-carbamoyl-D-amino acid + 2 H(+) + H2O = a D-alpha-amino acid + CO2 + NH4(+)

RHEA:13457 3-methyl-2-oxobutanoate + [dihydrolipoyllysine-residue (2-methylpropanoyl)transferase]-(R)-N(6)-lipoyl-L-lysine + H(+) = [dihydrolipoyllysine-residue (2-methylpropanoyl)transferase]-(R)-N(6)-(S(8)-2-methylpropanoyldihydrolipoyl)-L-lysine + CO2

RHEA:14397 (3E,5R)-5-carboxy-2-oxohept-3-enedioate + H(+) = (4Z)-2-oxohept-4-enedioate + CO2

RHEA:14509 2-oxoglutarate + mugineate + O2 = 3-epihydroxymugineate + CO2 + H(+) + succinate

RHEA:14993 acetyl-CoA + 2n H(+) + n malonyl-CoA + 2n NADPH = a long-chain fatty acid + n CO2 + (n+1) CoA + 2n NADP(+)

RHEA:17677 2-(acetamidomethylene)-3-(hydroxymethyl)succinate + H(+) + 2 H2O = 2-(hydroxymethyl)-4-oxobutanoate + acetate + CO2 + NH4(+)

RHEA:19189 [dihydrolipoyllysine-residue acetyltransferase]-(R)-N(6)-lipoyl-L-lysine + H(+) + pyruvate = [dihydrolipoyllysine-residue acetyltransferase]-(R)-N(6)-(S(8)-acetyldihydrolipoyl)-L-lysine + CO2

RHEA:19305 3-hydroxybenzoyl-CoA + 2 H(+) + 3 malonyl-CoA = 2,3',4,6-tetrahydroxybenzophenone + 3 CO2 + 4 CoA

RHEA:20065 2'-deoxymugineate + 2-oxoglutarate + O2 = 3-epihydroxy-2'-deoxymugineate + CO2 + H(+) + succinate

RHEA:21376 3-(4-hydroxyphenyl)pyruvate + O2 = (S)-4-hydroxymandelate + CO2

RHEA:21648 H(+) + prephenate = 3-phenylpyruvate + CO2 + H2O

RHEA:21652 2-chlorobenzoate + H(+) + NADH + O2 = catechol + chloride + CO2 + NAD(+)

RHEA:21912 CoA + H(+) + O2 + pyruvate = acetyl-CoA + CO2 + H2O2

RHEA:22292 benzoyl-CoA + 3 H(+) + 3 malonyl-CoA = biphenyl-3,5-diol + 4 CO2 + 4 CoA

RHEA:22500 H(+) + malonyl-CoA + trans-feruloyl-CoA = CO2 + CoA + trans-feruloylacetyl-CoA

RHEA:23348 (R)-2-(carboxymethyl)-5-oxo-2,5-dihydro-2-furoate + H(+) = (4,5-dihydro-5-oxofuran-2-yl)-acetate + CO2

RHEA:23572 3-methylbutanoyl-CoA + 3 H(+) + 3 malonyl-CoA = 3 CO2 + 4 CoA + phlorisovalerophenone

RHEA:24028 2-oxoglutarate + 4-(trimethylamino)butanoate + O2 = carnitine + CO2 + succinate

RHEA:24608 5-dehydro-4-deoxy-D-glucarate + H(+) = 2,5-dioxopentanoate + CO2 + H2O

RHEA:28082 (2S)-ethylmalonyl-CoA + NADP(+) = (2E)-butenoyl-CoA + CO2 + NADPH

RHEA:29071 a ubiquinone + formate + H(+) = a ubiquinol + CO2

RHEA:33295 L-hexahomomethionine + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = (E)-9-(methylsulfanyl)nonanal oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]

RHEA:36067 Co-precorrin-6B + S-adenosyl-L-methionine = Co-precorrin-7 + CO2 + S-adenosyl-L-homocysteine

RHEA:36491 (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA + H(+) + malonyl-CoA = (9Z,12Z,15Z,18Z,21Z)-3-oxotetracosapentaenoyl-CoA + CO2 + CoA

RHEA:36603 2-oxoglutarate + L-enduracididine + O2 = (3S)-3-hydroxy-L-enduracididine + CO2 + succinate

RHEA:36607 2-oxoglutarate + L-arginine + O2 = (2S,3S)-hydroxyarginine + CO2 + succinate

RHEA:36967 (10Z,13Z,16Z,19Z,22Z,25Z)-octacosahexaenoyl-CoA + H(+) + malonyl-CoA = 3-oxo-(12Z,15Z,18Z,21Z,24Z,27Z)-triacontahexaenoyl-CoA + CO2 + CoA

RHEA:37003 (11Z,14Z,17Z)-eicosatrienoyl-CoA + H(+) + malonyl-CoA = 3-oxo-(13Z,16Z,19Z)-docosatrienoyl-CoA + CO2 + CoA

RHEA:37127 2-oxoglutarate + dioxidophosphate + H2O2 = CO2 + H(+) + phosphonate + succinate

RHEA:37243 (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA + H(+) + malonyl-CoA = 3-oxo-(11Z,14Z,17Z,20Z,23Z)-hexacosapentaenoyl-CoA + CO2 + CoA

RHEA:37339 3-(carbamoylamino)-2-methylpropanoate + 2 H(+) + H2O = (R)-3-amino-2-methylpropanoate + CO2 + NH4(+)

RHEA:37995 all-trans-nonaprenyl diphosphate + H(+) + homogentisate = 2-methyl-6-all-trans-nonaprenylbenzene-1,4-diol + CO2 + diphosphate

RHEA:38143 carbon disulfide + 2 H2O = CO2 + 2 H(+) + 2 hydrogen sulfide

RHEA:38151 carbonyl sulfide + H2O = CO2 + H(+) + hydrogen sulfide

RHEA:39679 (11Z)-octadecenoyl-CoA + H(+) + malonyl-CoA = 3-oxo-(13Z)-eicosenoyl-CoA + CO2 + CoA

RHEA:41420 2 3-amino-4-hydroxybenzoate + H(+) + N-acetyl-L-cysteine + 2 O2 = CO2 + grixazone B + 4 H2O

RHEA:42032 2 2-oxoglutarate + N(6),N(6)-dimethyl-L-lysyl(36)-[histone H3] + 2 O2 = 2 CO2 + 2 formaldehyde + L-lysyl(36)-[histone H3] + 2 succinate

RHEA:42356 (9Z)-tetradecenoyl-CoA + H(+) + malonyl-CoA = 3-oxo-(11Z)-hexadecenoyl-CoA + CO2 + CoA

RHEA:42616 (Z)-3-ureidoacrylate peracid + H(+) + H2O = (Z)-3-aminoperacrylic acid + CO2 + NH4(+)

RHEA:42620 (Z)-2-methylureidoacrylate peracid + H(+) + H2O = (Z)-2-hydroxy-3-aminoperacrylic acid + CO2 + NH4(+)

RHEA:42624 (Z)-3-ureidoacrylate + H(+) + H2O = (Z)-3-aminoacrylate + CO2 + NH4(+)

RHEA:43652 decanoyl-CoA + H(+) + malonyl-[ACP] = 3-oxododecanoyl-[ACP] + CO2 + CoA

RHEA:45792 2-oxoglutarate + [ribosomal protein S23]-L-proline + O2 = [ribosomal protein S23]-trans-3-hydroxy-L-proline + CO2 + succinate

RHEA:47160 4alpha-carboxyl-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol + NAD(+) = 4alpha-methyl-5alpha-cholesta-8,24-dien-3-one + CO2 + NADH

RHEA:47168 4alpha-carboxy-4beta-methyl-5alpha-cholest-8-en-3beta-ol + NAD(+) = 4alpha-methyl-5alpha-cholest-8-en-3-one + CO2 + NADH

RHEA:47172 4alpha-carboxy-5alpha-cholest-8-ene-3beta-ol + NAD(+) = 5alpha-cholest-8-en-3-one + CO2 + NADH

RHEA:48936 2-oxoglutarate + [Skp1 protein]-L-proline + O2 = [Skp1 protein]-trans-4-hydroxy-L-proline + CO2 + succinate

RHEA:49524 2-oxoglutarate + an N(6)-methyl-2'-deoxyadenosine in DNA + O2 = a 2'-deoxyadenosine in DNA + CO2 + formaldehyde + succinate

RHEA:50312 2-oxopentanoate + H(+) = butanal + CO2

RHEA:51488 archaetidylserine + H(+) = archaetidylethanolamine + CO2

RHEA:52396 4-O-phospho-D-threonate + NAD(+) = CO2 + dihydroxyacetone phosphate + NADH

RHEA:52404 3-dehydro-4-O-phospho-L-erythronate + H(+) = CO2 + dihydroxyacetone phosphate

RHEA:52408 4-phospho-D-erythronate + NAD(+) = CO2 + dihydroxyacetone phosphate + NADH

RHEA:52416 3-dehydro-4-O-phospho-D-erythronate + H(+) = CO2 + dihydroxyacetone phosphate

RHEA:53956 H(+) + L-glutamyl-[BtrI ACP] = 4-aminobutanoyl-[BtrI ACP] + CO2

RHEA:54156 2-oxoglutarate + [ribosomal protein uS12]-L-proline + O2 = [ribosomal protein uS12]-(3S)-3-hydroxy-L-proline + CO2 + succinate

RHEA:54160 2-oxoglutarate + [ribosomal protein uS12]-(3S)-3-hydroxy-L-proline + O2 = [ribosomal protein uS12]-(3S)-3,4-dihydroxy-L-proline + CO2 + succinate

RHEA:54280 2-oxoglutarate + L-aspartyl-[ankyrin-repeat domain protein] + O2 = (3S)-3-hydroxy-L-aspartyl-[ankyrin-repeat domain protein] + CO2 + succinate

RHEA:54924 (7Z)-tetradecenoyl-[ACP] + H(+) + malonyl-[ACP] = 3-oxo-(9Z)-hexadecenoyl-[ACP] + CO2 + holo-[ACP]

RHEA:54940 (3Z)-decenoyl-[ACP] + H(+) + malonyl-[ACP] = 3-oxo-(5Z)-dodecenoyl-[ACP] + CO2 + holo-[ACP]

RHEA:55524 H(+) + H2O + L-dopa + O2 = 3,4-dihydroxyphenylacetaldehyde + CO2 + H2O2 + NH4(+)

RHEA:56348 4-hydroxybenzoate + 2 bromide + 5 H(+) + 2 NADPH + 2 O2 = 2,4-dibromophenol + CO2 + 4 H2O + 2 NADP(+)

RHEA:56356 3-bromo-4-hydroxybenzoate + bromide + 3 H(+) + NADPH + O2 = 2,4-dibromophenol + CO2 + 2 H2O + NADP(+)

RHEA:56368 3,4-dihydroxybenzoate + 2 bromide + 5 H(+) + 2 NADPH + 2 O2 = 3,5-dibromobenzene-1,2-diol + CO2 + 4 H2O + 2 NADP(+)

RHEA:56376 3-bromo-4,5-dihydroxybenzoate + bromide + 3 H(+) + NADPH + O2 = 3,5-dibromobenzene-1,2-diol + CO2 + 2 H2O + NADP(+)

RHEA:56700 (2S)-3-(1H-indol-3-yl)-2-isocyanopropanoate + 2-oxoglutarate + H(+) + O2 = 3-[(Z)-2-isocyanoethenyl]-1H-indole + 2 CO2 + H2O + succinate

RHEA:56864 12 H(+) + 6 malonyl-CoA + NADH + 5 NADPH = (2E,5S,6E,8E,10E)-5-hydroxydodeca-2,6,8,10-tetraenal + 6 CO2 + 6 CoA + 4 H2O + NAD(+) + 5 NADP(+)

RHEA:57032 (E)-2-((N-methylformamido) methylene)succinate + H(+) + 2 H2O = CO2 + formate + methylamine + succinate semialdehyde

RHEA:58028 5 (S)-methylmalonyl-CoA + a medium-chain fatty acyl-CoA + 32 H(+) + 5 malonyl-CoA + 22 NADPH = a mycoketide-CoA + 10 CO2 + 10 CoA + 11 H2O + 22 NADP(+)

RHEA:59884 2-oxoglutarate + chloride + H(+) + L-lysine + O2 = 4-chloro-L-lysine + CO2 + H2O + succinate

RHEA:10104 2-oxoglutarate + gibberellin A20 + O2 = CO2 + gibberellin A1 + succinate

RHEA:10744 (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate + NAD(+) = 3,4-dihydroxybenzoate + CO2 + NADH

RHEA:10904 [cypemycin](1-18)-L-Cys-L-Leu-L-Val-L-Cys + A = AH2 + C(3,19),S(21)-[cypemycin](1-18)-L-Ala-L-Leu-N-thioethenyl-L-valinamide + CO2 + hydrogen sulfide

RHEA:11340 5-guanidino-2-oxopentanoate + H(+) = 4-guanidinobutanal + CO2

RHEA:12000 formate + NADP(+) = CO2 + NADPH

RHEA:12536 H(+) + L-arogenate = CO2 + H2O + L-phenylalanine

RHEA:12749 3,4,5-trihydroxybenzoate + H(+) = 1,2,3-trihydroxybenzene + CO2

RHEA:12765 CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]

RHEA:14045 1-carboxyvinyl carboxyphosphonate + H(+) = 3-(hydrohydroxyphosphoryl)pyruvate + CO2

RHEA:14341 2-oxoglutarate + glyoxylate + H(+) = 2-hydroxy-3-oxoadipate + CO2

RHEA:14641 cyanurate + H2O = biuret + CO2

RHEA:15005 2-oxoglutarate + gibberellin A1 + O2 = CO2 + gibberellin A8 + succinate

RHEA:15253 cis-aconitate + H(+) = CO2 + itaconate

RHEA:15985 formate + NAD(+) = CO2 + NADH

RHEA:16877 3-sulfino-L-alanine + H(+) = CO2 + hypotaurine

RHEA:17297 2-oxoglutarate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] = CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin] + succinyl-CoA

RHEA:17477 precorrin-6B + 2 S-adenosyl-L-methionine = CO2 + 3 H(+) + precorrin-8X + 2 S-adenosyl-L-homocysteine

RHEA:17501 H2O + polyneuridine aldehyde = 16-epivellosimine + CO2 + methanol

RHEA:18017 H(+) + indole-3-pyruvate = CO2 + indole-3-acetaldehyde

RHEA:18057 O2 + Watasenia luciferin = CO2 + hnu + oxidized Watasenia luciferin

RHEA:18345 a cis-3-alkyl-4-alkyloxetan-2-one = a cis-alkene + CO2

RHEA:18621 2-oxoglutarate + a (2S)-flavan-4-one + O2 = a (2R,3R)-dihydroflavonol + CO2 + succinate

RHEA:20417 coelenterazine + O2 = CO2 + coelenteramide + hnu

RHEA:20848 H(+) + O2 + phosphate + pyruvate = acetyl phosphate + CO2 + H2O2

RHEA:21076 2'-deoxyuridine + 2-oxoglutarate + O2 = CO2 + succinate + uridine

RHEA:21108 (S)-3-methyl-2-oxopentanoate + H(+) = 2-methylbutanal + CO2

RHEA:21880 2 H(+) + O2 + oxalate = 2 CO2 + H2O2

RHEA:22620 H(+) + L-tryptophan + O2 = 3-indoleglycolaldehyde + CO2 + NH4(+)

RHEA:23368 H(+) + phenylglyoxylate = benzaldehyde + CO2

RHEA:23640 1-aminocyclopropane-1-carboxylate + L-ascorbate + O2 = CO2 + ethene + 2 H2O + hydrogen cyanide + L-dehydroascorbate

RHEA:23972 (E)-glutaconyl-CoA + H(+) + Na(+)(in) = (2E)-butenoyl-CoA + CO2 + Na(+)(out)

RHEA:25000 H(+) + N,N-dihydroxy-L-phenylalanine = (E)-phenylacetaldehyde oxime + CO2 + H2O

RHEA:25139 (2S)-2-amino-3-oxo-4-(phosphooxy)butanoate + H(+) = 3-amino-2-oxopropyl phosphate + CO2

RHEA:25698 H(+) + N,N-dihydroxy-L-hexahomomethionine = (E)-9-(methylsulfanyl)nonanal oxime + CO2 + H2O

RHEA:25706 H(+) + N,N-dihydroxy-L-dihomomethionine = (E)-5-(methylsulfanyl)pentanal oxime + CO2 + H2O

RHEA:25719 H(+) + N,N-dihydroxy-L-trihomomethionine = (E)-6-(methylsulfanyl)hexanal oxime + CO2 + H2O

RHEA:25731 H(+) + N,N-dihydroxy-L-tetrahomomethionine = (E)-7-(methylsulfanyl)heptanal oxime + CO2 + H2O

RHEA:25743 H(+) + N,N-dihydroxy-L-pentahomomethionine = (E)-8-(methylsulfanyl)octanal oxime + CO2 + H2O

RHEA:26478 1,4-dihydroxy-2-naphthoate + an all-trans-polyprenyl diphosphate + H(+) = a 2-demethylmenaquinol + CO2 + diphosphate

RHEA:27333 6-hydroxynicotinate + 2 H(+) + NADH + O2 = 2,5-dihydroxypyridine + CO2 + H2O + NAD(+)

RHEA:27666 (R)-methylmalonyl-CoA + H(+) = CO2 + propanoyl-CoA

RHEA:30099 1,4-dihydroxy-2-naphthoate + all-trans-octaprenyl diphosphate + H(+) = 2-demethylmenaquinol-8 + CO2 + diphosphate

RHEA:30179 oxalate + oxidized 2[4Fe-4S]-[ferredoxin] = 2 CO2 + reduced 2[4Fe-4S]-[ferredoxin]

RHEA:30487 H(+) + N,N-dihydroxy-L-isoleucine = (1E,2S)-2-methylbutanal oxime + CO2 + H2O

RHEA:30499 H(+) + N,N-dihydroxy-L-valine = (E)-2-methylpropanal oxime + CO2 + H2O

RHEA:31271 1-hydroxy-2-naphthoate + 2 H(+) + NADH + O2 = CO2 + H2O + NAD(+) + naphthalene-1,2-diol

RHEA:31523 2-oxoglutarate + 2 H(+) + O2 = 3 CO2 + ethene + H2O

RHEA:31531 2-oxoglutarate + L-arginine + O2 = CO2 + N(omega)-hydroxy-L-arginine + succinate

RHEA:31571 1-hydroxy-2-naphthoate + 2 H(+) + NADPH + O2 = CO2 + H2O + NADP(+) + naphthalene-1,2-diol

RHEA:32131 (2S)-ethylmalonyl-CoA + H(+) = butanoyl-CoA + CO2

RHEA:33091 1,4-dihydroxy-6-naphthoate + all-trans-octaprenyl diphosphate + H(+) = 2-demethylmenaquinol-8 + CO2 + diphosphate

RHEA:33279 L-tryptophan + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = (E)-(indol-3-yl)acetaldehyde oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]

RHEA:33455 4alpha-carboxy-5alpha-cholesta-8,24-dien-3beta-ol + NADP(+) = CO2 + NADPH + zymosterone

RHEA:34483 4-coumaroyl-CoA + H(+) + H2O + malonyl-CoA = 4-hydroxybenzalacetone + 2 CO2 + 2 CoA

RHEA:34619 1-deoxypentalenate + 2-oxoglutarate + O2 = 1-deoxy-11beta-hydroxypentalenate + CO2 + succinate

RHEA:34807 (R)-dihydrocamalexate + O2 + reduced [NADPH--hemoprotein reductase] = camalexin + CO2 + 2 H2O + oxidized [NADPH--hemoprotein reductase]

RHEA:34823 H2O + trans-feruloyl-CoA + trans-feruloylacetyl-CoA = CO2 + 2 CoA + curcumin

RHEA:35143 benzoyl-CoA + 2 H(+) + 3 malonyl-CoA = 2,4,6-trihydroxybenzophenone + 3 CO2 + 4 CoA

RHEA:35291 11-methyldodecanoyl-CoA + H(+) + malonyl-CoA = 3-oxoisopentadecanoyl-CoA + CO2 + CoA

RHEA:35335 H(+) + isopentadecanoyl-CoA + malonyl-CoA = 3-oxoisoheptadecanoyl-CoA + CO2 + CoA

RHEA:35379 (6Z,9Z,12Z)-octadecatrienoyl-CoA + H(+) + malonyl-CoA = (8Z,11Z,14Z)-3-oxoeicosatrienoyl-CoA + CO2 + CoA

RHEA:35675 H(+) + L-serine + tetradecanoyl-CoA = 3-oxohexadecasphinganine + CO2 + CoA

RHEA:35679 dodecanoyl-CoA + H(+) + L-serine = 3-oxotetradecasphinganine + CO2 + CoA

RHEA:36347 N(1)-methylguanosine(37) in tRNA(Phe) + pyruvate + S-adenosyl-L-methionine = 4-demethylwyosine(37) in tRNA(Phe) + 5'-deoxyadenosine + CO2 + H2O + L-methionine

RHEA:36503 (9Z,12Z)-octadecadienoyl-CoA + H(+) + malonyl-CoA = (11Z,14Z)-3-oxoicosa-11,14-dienoyl-CoA + CO2 + CoA

RHEA:36507 docosanoyl-CoA + H(+) + malonyl-CoA = 3-oxotetracosanoyl-CoA + CO2 + CoA

RHEA:36511 (9Z)-octadecenoyl-CoA + H(+) + malonyl-CoA = (11Z)-3-oxoicosenoyl-CoA + CO2 + CoA

RHEA:36515 H(+) + malonyl-CoA + tetracosanoyl-CoA = 3-oxohexacosanoyl-CoA + CO2 + CoA

RHEA:36663 (S)-1-pyrroline-5-carboxylate + H(+) + H2O + malonyl-CoA = (2S,5S)-5-carboxymethylproline + CO2 + CoA

RHEA:36807 H(+) + malonyl-CoA + octacosanoyl-CoA = 3-oxo-triacontanoyl-CoA + CO2 + CoA

RHEA:36859 (17Z,20Z,23Z,26Z,29Z)-dotriacontapentaenoyl-CoA + H(+) + malonyl-CoA = 3-oxo-(19Z,22Z,25Z,28Z,31Z)-tetratriacontapentaenoyl-CoA + CO2 + CoA

RHEA:37091 (8Z,11Z,14Z)-eicosatrienoyl-CoA + H(+) + malonyl-CoA = 3-oxo-(10Z,13Z,16Z)-docosatrienoyl-CoA + CO2 + CoA

RHEA:37227 (E,E)-sorbate + H(+) = (E)-1,3-pentadiene + CO2

RHEA:37899 2-oxoglutarate + 7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + O2 = 7-(2-hydroxy-3-amino-3-carboxypropyl)wyosine(37) in tRNA(Phe) + CO2 + succinate

RHEA:37975 H(+) + homogentisate + phytyl diphosphate = 2-methyl-6-phytyl-1,4-benzene-1,4-diol + CO2 + diphosphate

RHEA:38003 all-trans-geranylgeranyl diphosphate + H(+) + homogentisate = 6-geranylgeranyl-2-methylbenzene-1,4-diol + CO2 + diphosphate

RHEA:38367 8 H(+) + malonamoyl-[OxyC ACP] + 8 malonyl-CoA = 18-carbamoyl-3,5,7,9,11,13,15,17-octaoxooctadecanoyl-[OxyC ACP] + 8 CO2 + 8 CoA

RHEA:40955 (R)-5-phosphomevalonate + ATP = ADP + CO2 + isopentenyl phosphate + phosphate

RHEA:41524 5 H(+) + 5 malonyl-CoA = 5 CO2 + 5 CoA + H2O + naphthalene-1,3,6,8-tetrol

RHEA:41556 2-oxoglutarate + L-arginyl-[ribosomal protein uL16] + O2 = (3R)-3-hydroxy-L-arginyl-[ribosomal protein uL16] + CO2 + succinate

RHEA:42316 a 2-oxocarboxylate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] = an acyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]

RHEA:42832 (2E)-octenal + H(+) + pyruvate = (S)-3-acetyloctanal + CO2

RHEA:43452 2 H(+) + hexanoyl-CoA + 2 malonyl-CoA = 4-hydroxy-6-pentylpyran-2-one + 2 CO2 + 3 CoA

RHEA:43996 2-oxoglutarate + 3-methyl fatty acyl-CoA + O2 = 2-hydroxy-3-methyl fatty acyl-CoA + CO2 + succinate

RHEA:44000 2-oxoglutarate + 3-methylhexadecanoyl-CoA + O2 = 2-hydroxy-3-methylhexadecanoyl-CoA + CO2 + succinate

RHEA:44260 2 H(+) + hexadecanoyl-CoA + 2 malonyl-CoA = 4-hydroxy-6-pentadecylpyran-2-one + 2 CO2 + 3 CoA

RHEA:44268 3 H(+) + hexadecanoyl-CoA + 3 malonyl-CoA = 4-hydroxy-6-(2-oxoheptadecyl)pyran-2-one + 3 CO2 + 4 CoA

RHEA:44272 3 H(+) + 3 malonyl-CoA + octadecanoyl-CoA = 4-hydroxy-6-(2-oxononadecyl)pyran-2-one + 3 CO2 + 4 CoA

RHEA:44280 2 H(+) + 2 malonyl-CoA + octadecanoyl-CoA = 4-hydroxy-6-heptadecylpyran-2-one + 2 CO2 + 3 CoA

RHEA:45144 3-(methylsulfanyl)acryloyl-CoA + 2 H2O = acetaldehyde + CO2 + CoA + methanethiol

RHEA:46500 2-oxoglutarate + O2 + UMP = CO2 + phosphate + succinate + uridine-5'-aldehyde

RHEA:47620 2-ethylhexyl sulfate + 2-oxoglutarate + O2 = 2-ethylhexanal + CO2 + H(+) + succinate + sulfate

RHEA:49628 acetyl-CoA + 3 malonyl-CoA + 2 S-adenosyl-L-methionine = 3,5-dimethylorsellinate + 3 CO2 + 4 CoA + 2 S-adenosyl-L-homocysteine

RHEA:50396 (2-aminobenzoyl)acetate + H(+) + octanoyl-CoA = 2-heptyl-4-quinolone + CO2 + CoA + H2O

RHEA:50404 (2-aminobenzoyl)acetate + H(+) + S-octanoyl-L-cysteinyl-[PqsC protein] = 1-(2-aminophenyl)decane-1,3-dione + CO2 + L-cysteinyl-[PqsC protein]

RHEA:51508 2-oxoglutarate + L-proline + O2 = CO2 + succinate + trans-4-hydroxy-L-proline

RHEA:51980 an L-N,N-dihydroxypolyhomomethionine + H(+) = an (E)-omega-(methylsulfanyl)-alkanal oxime + CO2 + H2O

RHEA:53736 a 2-halobenzoate + H(+) + NADH + O2 = a halide anion + catechol + CO2 + NAD(+)

RHEA:54144 2 2-oxoglutarate + 5-methylcytidine(34) in mitochondrial tRNA(Met) + 2 O2 = 5-formylcytidine(34) in mitochondrial tRNA(Met) + 2 CO2 + H2O + 2 succinate

RHEA:54256 2-oxoglutarate + L-histidyl-[protein] + O2 = (3S)-3-hydroxy-L-histidyl-[protein] + CO2 + succinate

RHEA:54260 2-oxoglutarate + L-asparaginyl-[protein] + O2 = (3S)-3-hydroxy-L-asparaginyl-[protein] + CO2 + succinate

RHEA:54992 3 A + FMN + H2O + L-glutamate + O2 = 2-oxoglutarate + 8-amino-8-demethylriboflavin 5'-phosphate + 3 AH2 + CO2 + H(+)

RHEA:55072 2-oxobutanoate + H(+) = 1-propanal + CO2

RHEA:55076 4-methylsulfanyl-2-oxobutanoate + H(+) = 3-methylsulfanylpropanal + CO2

RHEA:55528 H(+) + H2O + L-tyrosine + O2 = (4-hydroxyphenyl)acetaldehyde + CO2 + H2O2 + NH4(+)

RHEA:55756 2-oxoglutarate + an N(2)-[(3R)-3-(2-saturated-acyloxy)acyl]-L-ornithine lipid + O2 = a 2-hydroxyornithine lipid + CO2 + succinate

RHEA:56180 8-carboxy-8-demethylriboflavin 5'-phosphate + 2 A + H2O + L-glutamate = 2-oxoglutarate + 8-amino-8-demethylriboflavin 5'-phosphate + 2 AH2 + CO2

RHEA:56520 Fe-coproporphyrin III + 2 S-adenosyl-L-methionine = 2 5'-deoxyadenosine + 2 CO2 + heme b + 2 L-methionine

RHEA:56764 12-epi-fischerindole U + 2-oxoglutarate + chloride + H(+) + O2 = 12-epi-fischerindole G + CO2 + H2O + succinate

RHEA:57356 2-oxoglutarate + chloride + H(+) + hapalindole U + O2 = CO2 + H2O + hapalindole G + succinate

RHEA:57612 20 H(+) + holo-[compactin nonaketide synthase] + 9 malonyl-CoA + 11 NADPH = 9 CO2 + 9 CoA + dihydro-ML-236C-[compactin nonaketide synthase] + 6 H2O + 11 NADP(+)

RHEA:57724 H(+) + 2 Na(+)(in) + oxaloacetate = CO2 + 2 Na(+)(out) + pyruvate

RHEA:57748 2 (S)-methylmalonyl-CoA + 10 H(+) + icosanoyl-[(phenol)carboxyphthiodiolenone synthase] + 3 malonyl-CoA + 5 NADPH = C32-carboxyphthiodiolenone-[(phenol)carboxyphthiodiolenone synthase] + 5 CO2 + 5 CoA + 2 H2O + 5 NADP(+)

RHEA:57752 2 (S)-methylmalonyl-CoA + docosanoyl-[(phenol)carboxyphthiodiolenone synthase] + 10 H(+) + 3 malonyl-CoA + 5 NADPH = C34-carboxyphthiodiolenone-[(phenol)carboxyphthiodiolenone synthase] + 5 CO2 + 5 CoA + 2 H2O + 5 NADP(+)

RHEA:57756 2 (S)-methylmalonyl-CoA + 17-(4-hydroxyphenyl)heptadecanoyl-[(phenol)carboxyphthiodiolenone synthase] + 10 H(+) + 3 malonyl-CoA + 5 NADPH = C35-(phenol)carboxyphthiodiolenone-[(phenol)carboxyphthiodiolenone synthase] + 5 CO2 + 5 CoA + 2 H2O + 5 NADP(+)

RHEA:57760 2 (S)-methylmalonyl-CoA + 19-(4-hydroxyphenyl)nonadecanoyl-[(phenol)carboxyphthiodiolenone synthase] + 10 H(+) + 3 malonyl-CoA + 5 NADPH = C37-(phenol)carboxyphthiodiolenone-[(phenol)carboxyphthiodiolenone synthase] + 5 CO2 + 5 CoA + 2 H2O + 5 NADP(+)

RHEA:57848 2-oxoglutarate + O2 + scopoletin = CO2 + fraxetin + succinate

RHEA:57856 2-oxoglutarate + O2 + trans-feruloyl-CoA = (E)-6-hydroxyferuloyl-CoA + CO2 + succinate

RHEA:58348 2 2-oxoglutarate + N(omega),N(omega)'-dimethyl-L-arginyl-[protein] + 2 O2 = 2 CO2 + 2 formaldehyde + L-arginyl-[protein] + 2 succinate

RHEA:58352 2-oxoglutarate + N(omega),N(omega)-dimethyl-L-arginyl-[protein] + O2 = CO2 + formaldehyde + N(omega)-methyl-L-arginyl-[protein] + succinate

RHEA:58356 2-oxoglutarate + N(omega)-methyl-L-arginyl-[protein] + O2 = CO2 + formaldehyde + L-arginyl-[protein] + succinate

RHEA:58468 2 2-oxoglutarate + N(omega),N(omega)-dimethyl-L-arginyl-[protein] + 2 O2 = 2 CO2 + 2 formaldehyde + L-arginyl-[protein] + 2 succinate

RHEA:58472 2-oxoglutarate + N(omega),N(omega)'-dimethyl-L-arginyl-[protein] + O2 = CO2 + formaldehyde + N(omega)-methyl-L-arginyl-[protein] + succinate

RHEA:59016 4alpha-carboxy-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-3beta-ol + NAD(+) = CO2 + cycloeucalenone + NADH

RHEA:59380 4-amino-4-deoxyprephenate + NAD(+) = 3-(4-aminophenyl)pyruvate + CO2 + H(+) + NADH

RHEA:59540 (2R)-ethylmalonyl-CoA + H(+) = butanoyl-CoA + CO2

RHEA:10448 2-oxoglutarate + a flavanone + O2 = a flavone + CO2 + H2O + succinate

RHEA:10784 2-oxoglutarate + N(6)-methyl-L-lysyl(36)-[histone H3] + O2 = CO2 + formaldehyde + L-lysyl(36)-[histone H3] + succinate

RHEA:11492 H(+) + O-phospho-L-threonine = (R)-1-aminopropan-2-yl phosphate + CO2

RHEA:11560 (1R,6S)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate + NAD(+) = catechol + CO2 + NADH

RHEA:12200 2'-deoxymugineate + 2-oxoglutarate + O2 = CO2 + mugineate + succinate

RHEA:12552 (E)-cinnamoyl-CoA + 3 H(+) + 3 malonyl-CoA = (E)-pinosylvin + 4 CO2 + 4 CoA

RHEA:12621 H(+) + L-aspartate = CO2 + L-alanine

RHEA:12733 CO2 + diphosphate + nicotinate beta-D-ribonucleotide = 5-phospho-alpha-D-ribose 1-diphosphate + 2 H(+) + quinolinate

RHEA:13981 2 [Fe(III)-cytochrome b561] + CO + H2O = 2 [Fe(II)-cytochrome b561] + CO2 + 2 H(+)

RHEA:14181 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysine + O2 = (3S)-3-hydroxy-N(6),N(6),N(6)-trimethyl-L-lysine + CO2 + succinate

RHEA:14185 3-phenylpyruvate + H(+) = 2-phenylacetaldehyde + CO2

RHEA:15189 2 [Fe(III)cytochrome c553] + formate = 2 [Fe(II)cytochrome c553] + CO2 + H(+)

RHEA:15425 coproporphyrinogen III + 2 S-adenosyl-L-methionine = 2 5'-deoxyadenosine + 2 CO2 + 2 L-methionine + protoporphyrinogen IX

RHEA:15689 H(+) + L-2,4-diaminobutanoate = CO2 + propane-1,3-diamine

RHEA:16073 2,2-dialkylglycine + H(+) + pyruvate = CO2 + dialkyl ketone + L-alanine

RHEA:17425 CoA + NADP(+) + pyruvate = acetyl-CoA + CO2 + NADPH

RHEA:17581 an N-carbamoyl-L-2-amino acid + 2 H(+) + H2O = an L-alpha-amino acid + CO2 + NH4(+)

RHEA:18565 19 H(+) + holo-[lovastatin nonaketide synthase] + 9 malonyl-CoA + 11 NADPH + S-adenosyl-L-methionine = 9 CO2 + 9 CoA + dihydromonacolin L-[lovastatin nonaketide synthase] + 6 H2O + 11 NADP(+) + S-adenosyl-L-homocysteine

RHEA:18617 ATP + oxaloacetate = ADP + CO2 + phosphoenolpyruvate

RHEA:19093 2 H(+) + siroheme = 12,18-didecarboxysiroheme + 2 CO2

RHEA:19865 4 H(+) + uroporphyrinogen III = 4 CO2 + coproporphyrinogen III

RHEA:20057 2 H(+) + H2O + N-carbamoylsarcosine = CO2 + NH4(+) + sarcosine

RHEA:20265 2-oxoglutarate + L-proline + O2 = cis-3-hydroxy-L-proline + CO2 + succinate

RHEA:20748 2-oxoglutarate + O2 + penicillin N = CO2 + deacetoxycephalosporin C + H2O + succinate

RHEA:20768 3-phosphonopyruvate + H(+) = CO2 + phosphonoacetaldehyde

RHEA:20828 1,2-diacyl-sn-glycero-3-phospho-L-serine + H(+) = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CO2

RHEA:21040 CO + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] = CO2 + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]

RHEA:21492 2,3-dihydroxybenzoate + H(+) = catechol + CO2

RHEA:21788 2-oxoglutarate + N(6),N(6)-dimethyl-L-lysyl(36)-[histone H3] + O2 = CO2 + formaldehyde + N(6)-methyl-L-lysyl(36)-[histone H3] + succinate

RHEA:22732 4-hydroxyphenylacetate + H(+) = 4-methylphenol + CO2

RHEA:22872 2-oxoglutarate + L-prolyl-[procollagen] + O2 = CO2 + succinate + trans-3-hydroxy-L-prolyl-[procollagen]

RHEA:22896 acetyl-CoA + 2n H(+) + n malonyl-CoA + 2n NADPH = a long-chain fatty acyl-CoA + n CO2 + n CoA + H2O + 2n NADP(+)

RHEA:23044 H(+) + N,N-dihydroxy-L-tyrosine = (E)-4-hydroxyphenylacetaldehyde oxime + CO2 + H2O

RHEA:23476 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate + H(+) = (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O

RHEA:23632 D-threo-isocitrate + NAD(+) = 2-oxoglutarate + CO2 + NADH

RHEA:24460 H(+) + malonyl-[ACP] = acetyl-[ACP] + CO2

RHEA:24865 (3R)-3-hydroxy-16-methoxy-2,3-dihydrotabersonine + 2-oxoglutarate + O2 = 4-O-deacetyl-16-O-demethylvindoline + CO2 + succinate

RHEA:24960 apo-[aequorin] + 3 Ca(2+) + coelenterazine + O2 = [excited state blue fluorescent protein] + CO2

RHEA:25249 H(+) + 2 pyruvate = (2S)-2-acetolactate + CO2

RHEA:25593 2-oxoglutarate + H(+) + isochorismate = 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate + CO2

RHEA:26301 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + H(+) = (S)-allantoin + CO2

RHEA:27314 dichlorochromopyrrolate + 6 H(+) + 4 NADH + 4 O2 = 2 CO2 + dichloroarcyriaflavin A + 6 H2O + 4 NAD(+)

RHEA:27405 a ubiquinone + H2O + pyruvate = a ubiquinol + acetate + CO2

RHEA:27654 2-oxobutanoate + H(+) + pyruvate = (S)-2-ethyl-2-hydroxy-3-oxobutanoate + CO2

RHEA:28602 L-isoleucine + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = (1E,2S)-2-methylbutanal oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]

RHEA:28606 L-valine + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = (E)-2-methylpropanal oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]

RHEA:30339 H(+) + L-tryptophan = CO2 + tryptamine

RHEA:31535 2-oxoglutarate + L-arginine + O2 = (S)-1-pyrroline-5-carboxylate + CO2 + guanidine + H(+) + H2O + succinate

RHEA:32271 (2R,3S)-3-isopropylmalate + NAD(+) = 4-methyl-2-oxopentanoate + CO2 + NADH

RHEA:32719 L-dihomomethionine + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = (E)-5-(methylsulfanyl)pentanal oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]

RHEA:32723 L-trihomomethionine + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = (E)-6-(methylsulfanyl)hexanal oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]

RHEA:33243 L-tetrahomomethionine + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = (E)-7-(methylsulfanyl)heptanal oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]

RHEA:33263 L-phenylalanine + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = (E)-phenylacetaldehyde oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]

RHEA:33291 L-pentahomomethionine + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = (E)-8-(methylsulfanyl)octanal oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]

RHEA:33499 H(+) + prephenate = 3-[(4R)-4-hydroxycyclohexa-1,5-dien-1-yl]-2-oxopropanoate + CO2

RHEA:34119 3 H(+) + hexanoyl-CoA + 3 malonyl-CoA = 3,5,7-trioxododecanoyl-CoA + 3 CO2 + 3 CoA

RHEA:34535 H(+) + hexadecanoyl-CoA + L-alanine = 1-deoxy-3-dehydrosphinganine + CO2 + CoA

RHEA:34771 a 3beta-hydroxysteroid-4alpha-carboxylate + NADP(+) = a 3-oxosteroid + CO2 + NADPH

RHEA:34775 a 3beta-hydroxysteroid-4alpha-carboxylate + NAD(+) = a 3-oxosteroid + CO2 + NADH

RHEA:35179 6 H(+) + hexanoyl-[ACP] + 7 malonyl-CoA = 7 CO2 + 7 CoA + 2 H2O + holo-[ACP] + noranthrone

RHEA:35327 eicosanoyl-CoA + H(+) + malonyl-CoA = 3-oxodocosanoyl-CoA + CO2 + CoA

RHEA:35759 8-O-methylsterigmatocystin + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = aflatoxin B1 + CO2 + 2 H(+) + H2O + methanol + 2 oxidized [NADPH--hemoprotein reductase]

RHEA:35763 8-O-methyldihydrosterigmatocystin + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = aflatoxin B2 + CO2 + 2 H(+) + H2O + methanol + 2 oxidized [NADPH--hemoprotein reductase]

RHEA:36479 (7Z,10Z,13Z,16Z)-docosatetraenoyl-CoA + H(+) + malonyl-CoA = (9Z,12Z,15Z,18Z)-3-oxotetracosatetraenoyl-CoA + CO2 + CoA

RHEA:36711 ATP + H(+) + H2O + O-ureido-D-serine = ADP + CO2 + D-cycloserine + NH4(+) + phosphate

RHEA:37119 7-[(3S)-(3-amino-3-methoxycarbonyl)propyl]wyosine(37) in tRNA(Phe) + CO2 + S-adenosyl-L-methionine = 2 H(+) + S-adenosyl-L-homocysteine + wybutosine(37) in tRNA(Phe)

RHEA:37815 (R)-2-(4-chloro-2-methylphenoxy)propanoate + 2-oxoglutarate + O2 = 2-methyl-4-chlorophenol + CO2 + pyruvate + succinate

RHEA:37823 (R)-(2,4-dichlorophenoxy)propanoate + 2-oxoglutarate + O2 = 2,4-dichlorophenol + CO2 + pyruvate + succinate

RHEA:37827 (S)-(2,4-dichlorophenoxy)propanoate + 2-oxoglutarate + O2 = 2,4-dichlorophenol + CO2 + pyruvate + succinate

RHEA:37831 (S)-2-(4-chloro-2-methylphenoxy)propanoate + 2-oxoglutarate + O2 = 2-methyl-4-chlorophenol + CO2 + pyruvate + succinate

RHEA:38543 H(+) + malonyl-CoA + S-anthraniloyl-L-cysteinyl-[PqsD protein] = (2-aminobenzoyl)acetyl-CoA + CO2 + L-cysteinyl-[PqsD protein]

RHEA:39167 H(+) + malonyl-CoA + tetradecanoyl-CoA = 3-oxohexadecanoyl-CoA + CO2 + CoA

RHEA:41800 acetyl-[ACP] + H(+) + malonyl-[ACP] = 3-oxobutanoyl-[ACP] + CO2 + holo-[ACP]

RHEA:42256 H(+) + hexanoyl-CoA + malonyl-[ACP] = 3-oxooctanoyl-[ACP] + CO2 + CoA

RHEA:42764 formate + 2 H(+) + oxidized coenzyme F420-(gamma-Glu)(n) = CO2 + reduced coenzyme F420-(gamma-Glu)(n)

RHEA:42852 3 H(+) + holo-[2-methylbutanoate polyketide synthase] + 2 malonyl-CoA + 2 NADPH + S-adenosyl-L-methionine = (S)-2-methylbutanoyl-[2-methylbutanoate polyketide synthase] + 2 CO2 + 2 CoA + H2O + 2 NADP(+) + S-adenosyl-L-homocysteine

RHEA:43368 dodecanoyl-CoA + 3 H(+) + 3 malonyl-CoA = 4-hydroxy-6-(2-oxotridecyl)pyran-2-one + 3 CO2 + 4 CoA

RHEA:43460 dodecanoyl-CoA + 2 H(+) + 2 malonyl-CoA = 4-hydroxy-6-undecylpyran-2-one + 2 CO2 + 3 CoA

RHEA:43640 dodecanoyl-CoA + H(+) + malonyl-[ACP] = 3-oxotetradecanoyl-[ACP] + CO2 + CoA

RHEA:43644 H(+) + malonyl-[ACP] + tetradecanoyl-CoA = 3-oxohexadecanoyl-[ACP] + CO2 + CoA

RHEA:43648 H(+) + hexadecanoyl-CoA + malonyl-[ACP] = 3-oxooctadecanoyl-[ACP] + CO2 + CoA

RHEA:45140 2,3-epoxyphylloquinone + 4-carboxy-L-glutamyl-[protein] + H(+) + H2O = CO2 + L-glutamyl-[protein] + O2 + phylloquinol

RHEA:45800 15-demethylaclacinomycin T + AH2 + O2 = 10-decarboxymethylaclacinomycin T + A + CO2 + H2O

RHEA:47164 4alpha-carboxy-5alpha-cholesta-8,24-dien-3beta-ol + NAD(+) = CO2 + NADH + zymosterone

RHEA:48592 a quinone + formate + H(+) = a quinol + CO2

RHEA:48984 (2,4-dichlorophenoxy)acetate + 2-oxoglutarate + O2 = 2,4-dichlorophenol + CO2 + glyoxylate + succinate

RHEA:49720 2 H(+) + NADH + 2 O2 + protoviolaceinate = CO2 + 2 H2O + NAD(+) + violacein

RHEA:49728 2 H(+) + NADPH + 2 O2 + protoviolaceinate = CO2 + 2 H2O + NADP(+) + violacein

RHEA:49732 H(+) + O2 + violaceinate = CO2 + H2O + violacein

RHEA:49736 2 H(+) + NADH + 2 O2 + protodeoxyviolaceinate = CO2 + deoxyviolacein + 2 H2O + NAD(+)

RHEA:49740 2 H(+) + NADPH + 2 O2 + protodeoxyviolaceinate = CO2 + deoxyviolacein + 2 H2O + NADP(+)

RHEA:49744 deoxyviolaceinate + H(+) + O2 = CO2 + deoxyviolacein + H2O

RHEA:49748 2 H(+) + NADPH + 2 O2 + protodeoxyviolaceinate = CO2 + 2 H2O + NADP(+) + proviolacein

RHEA:49752 2 H(+) + NADH + 2 O2 + protodeoxyviolaceinate = CO2 + 2 H2O + NAD(+) + proviolacein

RHEA:49756 H(+) + O2 + protoviolaceinate = CO2 + H2O + proviolacein

RHEA:50344 3 (S)-methylmalonyl-CoA + a holo-[mycolipanoate synthase] + a long-chain fatty acyl-CoA + 9 H(+) + 6 NADPH = a long-chain mycolipanoyl-[mycolipanoate synthase] + 3 CO2 + 4 CoA + 3 H2O + 6 NADP(+)

RHEA:50472 anthraniloyl-CoA + H(+) + malonyl-CoA = (2-aminobenzoyl)acetyl-CoA + CO2 + CoA

RHEA:50952 7-chloro-L-tryptophan + AH2 + O2 = A + CO2 + 2 H2O + monodechloroaminopyrrolnitrin

RHEA:51044 indole-3-pyruvate imine dimer = CO2 + NH4(+) + protodeoxyviolaceinate

RHEA:51972 an L-polyhomomethionine + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = an (E)-omega-(methylsulfanyl)-alkanal oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]

RHEA:52636 2-oxoglutarate + a 5-methyl-2'-deoxycytidine in DNA + O2 = a 5-hydroxymethyl-2'-deoxycytidine in DNA + CO2 + succinate

RHEA:54268 2-oxoglutarate + [hypoxia-inducible factor alpha subunit]-L-asparagine + O2 = [hypoxia-inducible factor alpha subunit]-(3S)-3-hydroxy-L-asparagine + CO2 + succinate

RHEA:54272 2-oxoglutarate + L-asparaginyl-[ankyrin-repeat domain protein] + O2 = (3S)-3-hydroxy-L-asparaginyl-[ankyrin-repeat domain protein] + CO2 + succinate

RHEA:55752 2 CO2 + coenzyme B + coenzyme M + 2 reduced [2Fe-2S]-[ferredoxin] = coenzyme M-coenzyme B heterodisulfide + 2 formate + 2 oxidized [2Fe-2S]-[ferredoxin]

RHEA:55888 [aequorin]--dioxetanone = [excited state blue fluorescent protein] + CO2

RHEA:56688 (2S)-3-(4-hydroxyphenyl)-2-isocyanopropanoate + 2-oxoglutarate + O2 = (2E)-3-(4-hydroxyphenyl)-2-isocyanoprop-2-enoate + CO2 + H2O + succinate

RHEA:56692 (2S)-3-(4-hydroxyphenyl)-2-isocyanopropanoate + 2-oxoglutarate + H(+) + O2 = 4-[(E)-2-isocyanoethenyl]phenol + 2 CO2 + H2O + succinate

RHEA:57868 (E)-4-coumaroyl-CoA + 2-oxoglutarate + O2 = (E)-2,4-dihydroxycinnamoyl-CoA + CO2 + succinate

RHEA:58360 2-oxoglutarate + L-lysyl-[protein] + O2 = (5S)-5-hydroxy-L-lysyl-[protein] + CO2 + succinate

RHEA:10136 2 glyoxylate + H(+) = 2-hydroxy-3-oxopropanoate + CO2

RHEA:10180 (6S)-10-formyltetrahydrofolate + H2O + NADP(+) = (6S)-5,6,7,8-tetrahydrofolate + CO2 + H(+) + NADPH

RHEA:10588 4 (R)-methylmalonyl-CoA + a long-chain acyl-[mycocerosate synthase] + 12 H(+) + 8 NADPH = a tetramethylated-mycocerosoyl-[mycocerosate synthase] + 4 CO2 + 4 CoA + 4 H2O + 8 NADP(+)

RHEA:10712 L-phenylalanine + O2 = 2-phenylacetamide + CO2 + H2O

RHEA:10764 (2R,3S,4S)-leucocyanidin + 2-oxoglutarate + O2 = (4S)-2,3-dehydroleucocyanidin + CO2 + H(+) + H2O + succinate

RHEA:10768 (2R,3S,4S)-3,4-leucopelargonidin + 2-oxoglutarate + O2 = (4S)-2,3-dehydroleucopelargonidin + CO2 + H(+) + H2O + succinate

RHEA:10792 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + H(+) = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + CO2

RHEA:11508 2-oxoglutarate + L-aspartyl-[protein] + O2 = 3-hydroxy-L-aspartyl-[protein] + CO2 + succinate

RHEA:11712 3-methyl-2-oxobutanoate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] = 2-methylpropanoyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]

RHEA:12240 acetyl-CoA + 3 H(+) + 3 malonyl-CoA + NADPH = 6-methylsalicylate + 3 CO2 + 4 CoA + H2O + NADP(+)

RHEA:12256 L-arogenate + NAD(+) = CO2 + L-tyrosine + NADH

RHEA:12272 H(+) + L-dopa = CO2 + dopamine

RHEA:12605 D-glyceraldehyde 3-phosphate + H(+) + pyruvate = 1-deoxy-D-xylulose 5-phosphate + CO2

RHEA:12645 CoA + indole-3-pyruvate + 2 oxidized [2Fe-2S]-[ferredoxin] = CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin] + S-2-(indol-3-yl)acetyl-CoA

RHEA:12773 2-oxoglutarate + O2 + proclavaminate = CO2 + dihydroclavaminate + H2O + succinate

RHEA:12921 glycine + H(+) + succinyl-CoA = 5-aminolevulinate + CO2 + CoA

RHEA:13389 glutaryl-CoA + 2 H(+) + oxidized [electron-transfer flavoprotein] = (2E)-butenoyl-CoA + CO2 + reduced [electron-transfer flavoprotein]

RHEA:14345 H(+) + L-tyrosine = CO2 + tyramine

RHEA:14565 (11Z)-hexadecenoyl-[ACP] + H(+) + malonyl-[ACP] = 3-oxo-(13Z)-octadecenoyl-[ACP] + CO2 + holo-[ACP]

RHEA:14765 coelenterazine h + O2 = CO2 + excited coelenteramide h monoanion + H(+) + hnu

RHEA:15101 H(+) + meso-2,6-diaminopimelate = CO2 + L-lysine

RHEA:15417 L-arogenate + NADP(+) = CO2 + L-tyrosine + NADPH

RHEA:15641 H(+) + oxaloacetate = CO2 + pyruvate

RHEA:15649 carbamate + 2 H(+) = CO2 + NH4(+)

RHEA:15805 7,8-diaminononanoate + ATP + CO2 = ADP + dethiobiotin + 3 H(+) + phosphate

RHEA:15821 2 A + glycine = 2 AH2 + CO2 + hydrogen cyanide

RHEA:15981 H(+) + S-adenosyl-L-methionine = CO2 + S-adenosyl 3-(methylsulfanyl)propylamine

RHEA:16065 2-oxoglutarate + O2 + phytanoyl-CoA = 2-hydroxyphytanoyl-CoA + CO2 + succinate

RHEA:16569 2-oxoglutarate + L-lysyl-[procollagen] + O2 = (5R)-5-hydroxy-L-lysyl-[procollagen] + CO2 + succinate

RHEA:16977 acetoacetate + coenzyme M + NADP(+) = 2-oxopropyl-coenzyme M + CO2 + NADPH

RHEA:18257 coproporphyrinogen III + 2 H(+) + O2 = 2 CO2 + 2 H2O + protoporphyrinogen IX

RHEA:18441 D-dopachrome + H(+) = 5,6-dihydroxyindole + CO2

RHEA:18973 2-oxoglutarate + deacetoxyvindoline + O2 = 4-O-deacetylvindoline + CO2 + succinate

RHEA:19381 H(+) + oxalosuccinate = 2-oxoglutarate + CO2

RHEA:19497 H(+) + L-aspartate = beta-alanine + CO2

RHEA:19629 isocitrate + NADP(+) = 2-oxoglutarate + CO2 + NADPH

RHEA:19785 2-oxoglutarate + dihydroclavaminate + O2 = clavaminate + CO2 + H2O + succinate

RHEA:19841 H2O + N-formylmethanofuran + 2 oxidized [2Fe-2S]-[ferredoxin] = CO2 + H(+) + methanofuran + 2 reduced [2Fe-2S]-[ferredoxin]

RHEA:20021 2-oxoglutarate + deoxyamidinoproclavaminate + O2 = amidinoproclavaminate + CO2 + succinate

RHEA:20557 2 H(+) + H2O + urea = CO2 + 2 NH4(+)

RHEA:21088 2-oxoglutarate + a (2R,3R)-dihydroflavonol + O2 = a flavonol + CO2 + H2O + succinate

RHEA:21396 (S)-methylmalonyl-CoA + H(+)(out) + Na(+)(in) = CO2 + Na(+)(out) + propanoyl-CoA

RHEA:22836 a fatty acyl-[ACP] + H(+) + malonyl-[ACP] = a 3-oxoacyl-[ACP] + CO2 + holo-[ACP]

RHEA:23068 6 (S)-methylmalonyl-CoA + 12 H(+) + 6 NADPH + propanoyl-CoA = 6-deoxyerythronolide B + 6 CO2 + 7 CoA + H2O + 6 NADP(+)

RHEA:23732 (R)-5-diphosphomevalonate + ATP = ADP + CO2 + isopentenyl diphosphate + phosphate

RHEA:24304 glycine + H(+) + N(6)-lipoyl-L-lysyl-[glycine-cleavage complex H protein] = (R)-N(6)-(S(8)-aminomethyldihydrolipoyl)-L-lysyl-[glycine-cleavage complex H protein] + CO2

RHEA:24702 NAD(+) + UDP-alpha-D-glucuronate = CO2 + NADH + UDP-beta-L-threo-pentopyranos-4-ulose

RHEA:27290 A + formate + H(+) = AH2 + CO2

RHEA:30299 2-oxoglutarate + a methylated nucleobase within DNA + O2 = a nucleobase within DNA + CO2 + formaldehyde + succinate

RHEA:32275 4-(phosphooxy)-L-threonine + NAD(+) = 3-amino-2-oxopropyl phosphate + CO2 + NADH

RHEA:32311 L-tyrosine + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = (E)-4-hydroxyphenylacetaldehyde oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]

RHEA:32483 H(+) + H2O + pheophorbide a = CO2 + methanol + pyropheophorbide a

RHEA:33023 6-phospho-D-gluconate + NAD(+) = CO2 + D-ribulose 5-phosphate + NADH

RHEA:33227 H(+) + trans-4-coumarate = 4-hydroxystyrene + CO2

RHEA:33239 L-threonine + NAD(+) = aminoacetone + CO2 + NADH

RHEA:33807 H(+) + trans-ferulate = 2-methoxy-4-vinylphenol + CO2

RHEA:34095 carboxyspermidine + H(+) = CO2 + spermidine

RHEA:34099 carboxynorspermidine + H(+) = CO2 + norspermidine

RHEA:34331 H(+) + indole-3-pyruvate + NADPH + O2 = (indol-3-yl)acetate + CO2 + H2O + NADP(+)

RHEA:34803 2 4-coumaroyl-CoA + H(+) + H2O + malonyl-CoA = bisdemethoxycurcumin + 2 CO2 + 3 CoA

RHEA:35315 H(+) + hexadecanoyl-CoA + malonyl-CoA = 3-oxooctadecanoyl-CoA + CO2 + CoA

RHEA:35391 (6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoA + H(+) + malonyl-CoA = (8Z,11Z,14Z,17Z)-3-oxoicosatetraenoyl-CoA + CO2 + CoA

RHEA:36483 (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + H(+) + malonyl-CoA = (7Z,10Z,13Z,16Z,19Z)-3-oxodocosapentaenoyl-CoA + CO2 + CoA

RHEA:36523 (9Z,12Z,15Z)-octadecatrienoyl-CoA + H(+) + malonyl-CoA = (11Z,14Z,17Z)-3-oxoeicosatrienoyl-CoA + CO2 + CoA

RHEA:36611 (3S,5S)-carbapenam-3-caboxylate + 2-oxoglutarate + O2 = (5R)-carbapenem-3-carboxylate + CO2 + H2O + succinate

RHEA:39675 (9Z)-hexadecenoyl-CoA + H(+) + malonyl-CoA = 3-oxo-(11Z)-octadecenoyl-CoA + CO2 + CoA

RHEA:41820 butanoyl-[ACP] + H(+) + malonyl-[ACP] = 3-oxohexanoyl-[ACP] + CO2 + holo-[ACP]

RHEA:41916 H(+) + hexadecanoyl-[ACP] + malonyl-[ACP] = 3-oxooctadecanoyl-[ACP] + CO2 + holo-[ACP]

RHEA:42264 H(+) + malonyl-[ACP] + octanoyl-CoA = 3-oxodecanoyl-[ACP] + CO2 + CoA

RHEA:42288 H(+) + L-alanine + pimeloyl-[ACP] = 8-amino-7-oxononanoate + CO2 + holo-[ACP]

RHEA:43120 2-oxoglutarate + O2 + xanthine = CO2 + succinate + urate

RHEA:43336 H(+) + N(6)-carboxybiotinyl-L-lysyl-[protein] + n Na(+)(in) = CO2 + N(6)-biotinyl-L-lysyl-[protein] + n Na(+)(out)

RHEA:44744 4 H(+) + 4 malonyl-CoA = (3,5-dihydroxyphenyl)acetyl-CoA + 4 CO2 + 3 CoA + H2O

RHEA:45740 2-oxoglutarate + L-ectoine + O2 = 5-hydroxyectoine + CO2 + succinate

RHEA:46096 3-phenylpropanoyl-CoA + 3 H(+) + 3 malonyl-CoA = 4 CO2 + 4 CoA + dihydropinosylvin

RHEA:46276 (S)-malate + H(+) = (S)-lactate + CO2

RHEA:46920 H(+) + trans-cinnamate = CO2 + styrene

RHEA:47740 1,4-dioxo-2-naphthoate + H(+) + phytyl diphosphate = CO2 + demethylphylloquinone + diphosphate

RHEA:47824 H(+) + malonyl-[ACP] + octadecanoyl-[ACP] = 3-oxoeicosanoyl-[ACP] + CO2 + holo-[ACP]

RHEA:48556 4-hydroxybenzoate + 5-phospho-alpha-D-ribose 1-diphosphate + H(+) = 4-(beta-D-ribofuranosyl)phenol 5'-phosphate + CO2 + diphosphate

RHEA:48976 5-methyl-phenazine-1-carboxylate + 2 H(+) + NADH + O2 = CO2 + H2O + NAD(+) + pyocyanin

RHEA:49516 2-oxoglutarate + N(1)-methyladenosine in mRNA + O2 = adenosine in mRNA + CO2 + formaldehyde + succinate

RHEA:50352 3 (R)-methylmalonyl-CoA + a long-chain acyl-[mycocerosate synthase] + 9 H(+) + 6 NADPH = a trimethylated-mycocerosoyl-[mycocerosate synthase] + 3 CO2 + 3 CoA + 3 H2O + 6 NADP(+)

RHEA:50464 4-hydroxyphenyl-[4-hydroxyphenylalkanoate synthase] + 24 H(+) + 8 malonyl-CoA + 16 NADPH = 17-(4-hydroxyphenyl)heptadecanoyl-[4-hydroxyphenylalkanoate synthase] + 8 CO2 + 8 CoA + 8 H2O + 16 NADP(+)

RHEA:50468 4-hydroxyphenyl-[4-hydroxyphenylalkanoate synthase] + 27 H(+) + 9 malonyl-CoA + 18 NADPH = 19-(4-hydroxyphenyl)nonadecanoyl-[4-hydroxyphenylalkanoate synthase] + 9 CO2 + 9 CoA + 9 H2O + 18 NADP(+)

RHEA:51616 ATP + formate + H(+) = CO2 + dATP + H2O

RHEA:51620 CTP + formate + H(+) = CO2 + dCTP + H2O

RHEA:51624 formate + GTP + H(+) = CO2 + dGTP + H2O

RHEA:51628 formate + H(+) + UTP = CO2 + dUTP + H2O

RHEA:52776 2-(L-cystein-S-yl)-2-(1H-indol-3-yl)-acetonitrile + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = camalexin + CO2 + 2 H(+) + 4 H2O + hydrogen cyanide + 2 oxidized [NADPH--hemoprotein reductase]

RHEA:53868 2 H(+) + NADH + O2 + phenazine-1-carboxylate = 1-hydroxyphenazine + CO2 + H2O + NAD(+)

RHEA:54124 coelenterazine h dioxetanone = CO2 + excited coelenteramide h monoanion + H(+)

RHEA:54432 2-oxoglutarate + a (2R,3S,4S)-leucoanthocyanidin + O2 = a 4-H-anthocyanidin with a 3-hydroxy group + CO2 + 2 H2O + succinate

RHEA:58820 H(+) + malonate + Na(+)(in) = acetate + CO2 + Na(+)(out)

RHEA:11120 cyanate + 3 H(+) + hydrogencarbonate = 2 CO2 + NH4(+)

RHEA:11128 4-coumaroyl-CoA + 2 H(+) + 3 malonyl-CoA = 2',4,4',6'-tetrahydroxychalcone + 3 CO2 + 4 CoA

RHEA:14353 3-dehydro-L-gulonate 6-phosphate + H(+) = CO2 + L-xylulose 5-phosphate

RHEA:14761 H(+) + hexadecanoyl-CoA + L-serine = 3-oxosphinganine + CO2 + CoA

RHEA:16189 3-(4-hydroxyphenyl)pyruvate + O2 = CO2 + homogentisate

RHEA:16805 2-oxoglutarate + deacetoxycephalosporin C + O2 = CO2 + deacetylcephalosporin C + succinate

RHEA:18489 cyanate + H(+) + hydrogencarbonate = carbamate + CO2

RHEA:19029 3 H(+) + H2O + urea-1-carboxylate = 2 CO2 + 2 NH4(+)

RHEA:24260 (3E)-2-oxohex-3-enedioate + H(+) = 2-oxopent-4-enoate + CO2

RHEA:36475 (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + H(+) + malonyl-CoA = (7Z,10Z,13Z,16Z)-3-oxodocosatetraenoyl-CoA + CO2 + CoA

RHEA:41680 a 4-hydroxy-3-all-trans-polyprenylbenzoate + H(+) = a 2-all-trans-polyprenylphenol + CO2

RHEA:41836 H(+) + hexanoyl-[ACP] + malonyl-[ACP] = 3-oxooctanoyl-[ACP] + CO2 + holo-[ACP]

RHEA:41852 H(+) + malonyl-[ACP] + octanoyl-[ACP] = 3-oxodecanoyl-[ACP] + CO2 + holo-[ACP]

RHEA:41868 decanoyl-[ACP] + H(+) + malonyl-[ACP] = 3-oxododecanoyl-[ACP] + CO2 + holo-[ACP]

RHEA:41884 dodecanoyl-[ACP] + H(+) + malonyl-[ACP] = 3-oxotetradecanoyl-[ACP] + CO2 + holo-[ACP]

RHEA:41900 H(+) + malonyl-[ACP] + tetradecanoyl-[ACP] = 3-oxohexadecanoyl-[ACP] + CO2 + holo-[ACP]

RHEA:42844 6 (S)-methylmalonyl-CoA + 12 H(+) + malonyl-CoA + 5 NADPH = 7 CO2 + 7 CoA + 2 H2O + 5 NADP(+) + narbonolide

RHEA:43056 5 (S)-methylmalonyl-CoA + 11 H(+) + malonyl-CoA + 5 NADPH = 10-deoxymethynolide + 6 CO2 + 6 CoA + 2 H2O + 5 NADP(+)

RHEA:48880 a quinone + CO + H2O = a quinol + CO2

RHEA:49464 2,6-dihydroxybenzoate + H(+) = CO2 + resorcinol

RHEA:49520 2-oxoglutarate + N(6)-methyladenosine in mRNA + O2 = adenosine in mRNA + CO2 + formaldehyde + succinate

RHEA:51476 a ribonucleoside 5'-triphosphate + formate + H(+) = a 2'-deoxyribonucleoside 5'-triphosphate + CO2 + H2O

RHEA:10116 6-phospho-D-gluconate + NADP(+) = CO2 + D-ribulose 5-phosphate + NADPH

RHEA:11184 3-(carbamoylamino)propanoate + 2 H(+) + H2O = beta-alanine + CO2 + NH4(+)

RHEA:11596 H(+) + orotidine 5'-phosphate = CO2 + UMP

RHEA:16509 H(+) + oxalate = CO2 + formate

RHEA:18781 H(+) + malonyl-CoA = acetyl-CoA + CO2

RHEA:18945 2-oxoglutarate + L-prolyl-[procollagen] + O2 = CO2 + succinate + trans-4-hydroxy-L-prolyl-[procollagen]

RHEA:23124 2 3-phospho-D-glycerate + 2 H(+) = CO2 + D-ribulose 1,5-bisphosphate + H2O

RHEA:25896 H(+) + malonate = acetate + CO2

RHEA:47844 2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2 H(+) = CO2 + diphosphate + thiamine phosphate

RHEA:47848 2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2 H(+) = CO2 + diphosphate + thiamine phosphate

RHEA:48400 2-oxoglutarate + [hypoxia-inducible factor alpha subunit]-L-proline + O2 = [hypoxia-inducible factor alpha subunit]-trans-4-hydroxy-L-proline + CO2 + succinate

RHEA:56516 Fe-coproporphyrin III + 2 H(+) + 2 H2O2 = 2 CO2 + 4 H2O + heme b

RHEA:57940 Fe-coproporphyrin III + H(+) + H2O2 = CO2 + 2 H2O + harderoheme III

RHEA:57944 H(+) + H2O2 + harderoheme III = CO2 + 2 H2O + heme b

RHEA:10748 H(+) + hydrogencarbonate = CO2 + H2O

RHEA:12080 acetyl-CoA + H(+) + malonyl-[ACP] = 3-oxobutanoyl-[ACP] + CO2 + CoA

RHEA:32727 a very-long-chain acyl-CoA + H(+) + malonyl-CoA = a very-long-chain 3-oxoacyl-CoA + CO2 + CoA