The Rhea reaction database welcomes new reaction submissions currently not annotated in Rhea. Rhea was designed to incorporate reactions independent of spatial location and catalysts. Rhea can also handle non-enzymatic reactions. For extensive information on the types of reactions that Rhea covers please consult our documentation.
All new reaction submissions should be posted on our SourceForge Reaction Requests/Updates tracker with relevant information to correctly annotate the reaction. Relevant information include the ChEBI identifiers for each participant in the reaction and also cross-references to other relevant databases. If the ChEBI identifiers are not available please provide a chemical structure, a name and formula if possible. It is also useful if at least one cross-reference or publication identifier can be provided.