Rhea is a manually annotated database of chemical reactions.

All data in Rhea is freely accessible and available for anyone to use.

Last release: 78.

Rhea release 78

A new release of Rhea, the annotated database of biochemical reactions, is available...

Reminder: on December 7th, 2015, the Rhea web page and web services have moved from http://www.ebi.ac.uk/rhea to http://www.rhea-db.org . Automatic redirects are in place.

The monthly release files stay on ftp://ftp.ebi.ac.uk/pub/databases/rhea/.

Rhea is a collaborative effort between the Swiss-Prot Group at the SIB Swiss Institute of Bioinformatics and the EMBL-EBI.
Rhea makes use of ChemAxon's Marvin tools.