Rhea is curated and developed by the Swiss-Prot Group at the SIB Swiss Institute of Bioinformatics.


Rhea curation and development is currently supported by the Swiss Federal Government through the State Secretariat for Education, Research and Innovation (SERI).

Previous support for Rhea was provided by the SwissLipids and LipidX projects of the Swiss Initiative in Systems Biology, by the EU Framework Programme 7 Collaborative Project MICROME, and by the ELIXIR Implementation study 'A microbial metabolism resource for Systems Biology'.

External resources

We thank the following groups and companies for the support that they provide to help us build Rhea and provide services to our users:

  • The ChEBI (Chemical Entities of Biological Interest) team at EMBL-EBI for their support, which is essential for the ongoing development of Rhea.
  • image for the chem-bioinformatics software that is used by Rhea curators to create new compounds for submission to ChEBI. Trusted by over one million active users, Chemaxon is renowned for industry-leading software supporting scientific discovery with calculation, search, and drawing tools.
  • EPAM Life Sciences for the open-source web-based chemical structure editor Ketcher that is used on the Rhea website for structure searches.