Rhea is curated and developed by the Swiss-Prot Group at the SIB Swiss Institute of Bioinformatics.


Rhea curation and development is currently supported by the Swiss Federal Government through the State Secretariat for Education, Research and Innovation (SERI).

Previous support for Rhea was provided by the SwissLipids and LipidX projects of the Swiss Initiative in Systems Biology, by the EU Framework Programme 7 Collaborative Project MICROME, and by the ELIXIR Implementation study 'A microbial metabolism resource for Systems Biology'.

External resources

Rhea is built on the ChEBI (Chemical Entities of Biological Interest) ontology of small molecules. We thank the ChEBI team at EMBL-EBI for their support, which is essential for the ongoing development of Rhea. We also thank ChemAxon (Software Solutions and Services for Chemistry and Biology), IDSM (Integrated Database of Small Molecules), Ketcher and InChITrust for the software and services they provide that help us to build Rhea and provide services to our users.