Current release 125 (2022-12-14): 15,453 reactions with 12,972 unique compounds from 17,256 unique references (see statistics and news)

Find Rhea reactions

Rhea is an expert-curated knowledgebase of chemical and transport reactions of biological interest - and the standard for enzyme and transporter annotation in UniProtKB. Rhea uses the chemical dictionary ChEBI (Chemical Entities of Biological Interest) to describe reaction participants. Learn more... Cite us: Rhea, the reaction knowledgebase in 2022 ( PMID:34755880, DOI:10.1093/nar/gkab1016)

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Chemical classes (ChEBI)

Chemical structures (InChIKey)


Gene Ontology


Enzyme classes (EC)

Enzymes (UniProt)

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