Rhea - reaction knowledgebase

Enzymes

UniProtKB ^help_outline	2,865 proteins
Enzyme class ^help_outline	EC 2.3.1.89 tetrahydrodipicolinate N-acetyltransferase
GO Molecular Function ^help_outline	GO:0047200 tetrahydrodipicolinate N-acetyltransferase activity

Reaction participants Show >> << Hide

Name ^help_outline (S)-2,3,4,5-tetrahydrodipicolinate Identifier CHEBI:16845 Charge -2 Formula C7H7NO4 InChIKey^help_outline CXMBCXQHOXUCEO-BYPYZUCNSA-L SMILES^help_outline [O-]C(=O)[C@@H]1CCCC(=N1)C([O-])=O 2D coordinates Mol file for the small molecule Search links Involved in 7 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
Name ^help_outline acetyl-CoA Identifier CHEBI:57288 (Beilstein: 8468140) ^help_outline Charge -4 Formula C23H34N7O17P3S InChIKey^help_outline ZSLZBFCDCINBPY-ZSJPKINUSA-J SMILES^help_outline CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP([O-])(=O)OP([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP([O-])([O-])=O)n1cnc2c(N)ncnc12 2D coordinates Mol file for the small molecule Search links Involved in 321 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
Name ^help_outline H₂O Identifier CHEBI:15377 (Beilstein: 3587155; CAS: 7732-18-5) ^help_outline Charge 0 Formula H2O InChIKey^help_outline XLYOFNOQVPJJNP-UHFFFAOYSA-N SMILES^help_outline [H]O[H] 2D coordinates Mol file for the small molecule Search links Involved in 6,048 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
Name ^help_outline CoA Identifier CHEBI:57287 (Beilstein: 11604429) ^help_outline Charge -4 Formula C21H32N7O16P3S InChIKey^help_outline RGJOEKWQDUBAIZ-IBOSZNHHSA-J SMILES^help_outline CC(C)(COP([O-])(=O)OP([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP([O-])([O-])=O)n1cnc2c(N)ncnc12)[C@@H](O)C(=O)NCCC(=O)NCCS 2D coordinates Mol file for the small molecule Search links Involved in 1,468 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
Name ^help_outline L-2-acetamido-6-oxoheptanedioate Identifier CHEBI:58117 Charge -2 Formula C9H11NO6 InChIKey^help_outline RVHKMLVNOXVQRH-LURJTMIESA-L SMILES^help_outline CC(=O)N[C@@H](CCCC(=O)C([O-])=O)C([O-])=O 2D coordinates Mol file for the small molecule Search links Involved in 2 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule

Cross-references

	RHEA:13085	RHEA:13086	RHEA:13087	RHEA:13088
Reaction direction	undefined	left-to-right	right-to-left	bidirectional
UniProtKB ^help_outline	2,865 proteins
EC numbers ^help_outline	2.3.1.89
Gene Ontology ^help_outline	GO:0047200
KEGG ^help_outline				R04364
MetaCyc ^help_outline		2.3.1.89-RXN

Publications

Bacterial distribution of the use of succinyl and acetyl blocking groups in diaminopimelic acid biosynthesis.

Weinberger S., Gilvarg C.

The use of acetate, rather than succinate, as a blocking group in diaminopimelate biosynthesis has been found only in species of the genus Bacillus.

J. Bacteriol. 101:323-324(1970) [PubMed] [EuropePMC]

Comments

Published in Chatterjee, S.P. and White, P.J. Activities and regulation of the enzymes of lysine biosynthesis in a lysine-excreting strain of Bacillus megaterium. J Gen Microbiol 128:1073-1081 (1982) (https://doi.org/10.1099/00221287-128-5-1073)