Enzymes
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- Name help_outline 3'-phosphoadenylyl sulfate Identifier CHEBI:58339 Charge -4 Formula C10H11N5O13P2S InChIKeyhelp_outline GACDQMDRPRGCTN-KQYNXXCUSA-J SMILEShelp_outline Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP([O-])(=O)OS([O-])(=O)=O)[C@@H](OP([O-])([O-])=O)[C@H]1O 2D coordinates Mol file for the small molecule Search links Involved in 102 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
- Name help_outline α-D-glucosyl-(1→6)-α-D-glucosyl-(1→6)-α-D-glucosyl-(1→3)-1-alkyl-2-acylglycerol Identifier CHEBI:16295 Charge 0 Formula C22H36O19R2 SMILEShelp_outline OC[C@H]1O[C@H](OC[C@H]2O[C@H](OC[C@H]3O[C@H](OCC(CO[*])OC([*])=O)[C@H](O)[C@@H](O)[C@@H]3O)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@@H]1O 2D coordinates Mol file for the small molecule Search links Involved in 1 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
- Name help_outline 6-sulfo-α-D-glucosyl-(1→6)-α-D-glucosyl-(1→6)-α-D-glucosyl-(1→3)-1-alkyl-2-acylglycerol Identifier CHEBI:58028 Charge -1 Formula C22H35O22SR2 SMILEShelp_outline O[C@H]1[C@H](O)[C@@H](CO[C@H]2O[C@H](CO[C@H]3O[C@H](COS([O-])(=O)=O)[C@@H](O)[C@H](O)[C@H]3O)[C@@H](O)[C@H](O)[C@H]2O)O[C@H](OCC(CO[*])OC([*])=O)[C@@H]1O 2D coordinates Mol file for the small molecule Search links Involved in 1 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
- Name help_outline adenosine 3',5'-bisphosphate Identifier CHEBI:58343 Charge -4 Formula C10H11N5O10P2 InChIKeyhelp_outline WHTCPDAXWFLDIH-KQYNXXCUSA-J SMILEShelp_outline Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP([O-])([O-])=O)[C@@H](OP([O-])([O-])=O)[C@H]1O 2D coordinates Mol file for the small molecule Search links Involved in 137 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
- Name help_outline H+ Identifier CHEBI:15378 Charge 1 Formula H InChIKeyhelp_outline GPRLSGONYQIRFK-UHFFFAOYSA-N SMILEShelp_outline [H+] 2D coordinates Mol file for the small molecule Search links Involved in 9,176 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
Cross-references
| RHEA:13273 | RHEA:13274 | RHEA:13275 | RHEA:13276 | |
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| Reaction direction help_outline | undefined | left-to-right | right-to-left | bidirectional |
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Publications
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Biosynthesis in vitro of a sulfated triglucosyl monoalkylmonoacylglycerol by rat gastric mucosa.
Liau Y.H., Zdebska E., Slomiany A., Slomiany B.L.
A sulfotransferase activity which catalyzes the transfer of the sulfate ester group from 3'-phosphoadenosine 5'-phosphosulfate to triglucosyl monoalkylmonoacylglycerol to form sulfated triglucosyl monoalkylmonoacylglycerol (SO3H-6Glc alpha 1 leads to 6Glc alpha 1 leads to 6Glc alpha 1 leads to 3-1 ... >> More
A sulfotransferase activity which catalyzes the transfer of the sulfate ester group from 3'-phosphoadenosine 5'-phosphosulfate to triglucosyl monoalkylmonoacylglycerol to form sulfated triglucosyl monoalkylmonoacylglycerol (SO3H-6Glc alpha 1 leads to 6Glc alpha 1 leads to 6Glc alpha 1 leads to 3-1,(3)-O-alkyl-2-O-acylglycerol) has been demonstrated in the rat gastric mucosa. The most enzyme activity was found in the cytosol fraction. Optimum enzymatic activity was obtained using the detergent Triton X-100, F1-, and Mg2+ at a pH of 7.8. The ATP, ADP, and dithiothreitol had inhibitory effects on the sulfotransferase. The enzymatic activity increased proportionally, over a given range, with increased concentrations of both substrates and of enzyme. The apparent Km of the enzyme for triglucosyl monoalkylmonoacylglycerol was 6.9 x 10(-5) M, and for 3'-phosphoadenosine 5'-phosphosulfate, 8.5 x 10(-7) M. The enzyme did not catalyze the transfer of sulfate to galactosylceramide. The results of compositional analyses and permethylation studies of the 35S-labeled product of the enzymatic reaction established that the sulfate ester group is located at C-6 on the terminal glucose residue. << Less