Enzymes
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- Name help_outline a 2-deoxy-α-D-glucoside Identifier CHEBI:37449 Charge 0 Formula C6H11O5R SMILEShelp_outline OC[C@H]1O[C@@H](C[C@@H](O)[C@@H]1O)O[*] 2D coordinates Mol file for the small molecule Search links Involved in 10 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
- Name help_outline H2O Identifier CHEBI:15377 (Beilstein: 3587155; CAS: 7732-18-5) help_outline Charge 0 Formula H2O InChIKeyhelp_outline XLYOFNOQVPJJNP-UHFFFAOYSA-N SMILEShelp_outline [H]O[H] 2D coordinates Mol file for the small molecule Search links Involved in 6,048 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
- Name help_outline 2-deoxy-D-glucose Identifier CHEBI:84755 Charge 0 Formula C6H12O5 InChIKeyhelp_outline PMMURAAUARKVCB-CERMHHMHSA-N SMILEShelp_outline OC[C@H]1OC(O)C[C@@H](O)[C@@H]1O 2D coordinates Mol file for the small molecule Search links Involved in 3 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
- Name help_outline an alcohol Identifier CHEBI:30879 Charge 0 Formula HOR SMILEShelp_outline O[*] 2D coordinates Mol file for the small molecule Search links Involved in 1,506 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
Cross-references
| RHEA:15317 | RHEA:15318 | RHEA:15319 | RHEA:15320 | |
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| Reaction direction help_outline | undefined | left-to-right | right-to-left | bidirectional |
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Publications
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Identification of a glycosidase activity with apparent specificity for 2-deoxy-D-glucose in glycosidic linkage.
Canellakis Z.N., Bondy P.K., May J.A. Jr., Myers-Robfogel M.K., Sartorelli A.C.
2-Deoxy-D-glucose (dGlc) is a carbohydrate with significant activity as an inhibitor of glucose metabolism and as a precursor in the synthesis of glycosylated macromolecules; several of the enzymes associated with its metabolism remain uncharacterized. In the present report, the partial purificati ... >> More
2-Deoxy-D-glucose (dGlc) is a carbohydrate with significant activity as an inhibitor of glucose metabolism and as a precursor in the synthesis of glycosylated macromolecules; several of the enzymes associated with its metabolism remain uncharacterized. In the present report, the partial purification and some of the properties of a mammalian enzyme that appears to be relatively specific for the hydrolysis of dGlc bound in glycosidic linkage is described. The physiological function of this enzymatic activity is unknown. In addition, dGlc has been shown to be taken up by HTC cells in culture and incorporated into macromolecular bound form, both as dGlc and as 2-deoxygalactose which is formed from dGlc. << Less
Eur J Biochem 143:159-163(1984) [PubMed] [EuropePMC]
This publication is cited by 1 other entry.