Rhea - reaction knowledgebase

Enzymes

Enzyme class ^help_outline	EC 2.6.1.72 D-4-hydroxyphenylglycine transaminase
GO Molecular Function ^help_outline	GO:0047320 D-4-hydroxyphenylglycine transaminase activity

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Name ^help_outline D-4-hydroxyphenylglycine Identifier CHEBI:57475 Charge 0 Formula C8H9NO3 InChIKey^help_outline LJCWONGJFPCTTL-SSDOTTSWSA-N SMILES^help_outline [NH3+][C@@H](C([O-])=O)c1ccc(O)cc1 2D coordinates Mol file for the small molecule Search links Involved in 1 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
Name ^help_outline 2-oxoglutarate Identifier CHEBI:16810 (CAS: 64-15-3) ^help_outline Charge -2 Formula C5H4O5 InChIKey^help_outline KPGXRSRHYNQIFN-UHFFFAOYSA-L SMILES^help_outline [O-]C(=O)CCC(=O)C([O-])=O 2D coordinates Mol file for the small molecule Search links Involved in 449 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
Name ^help_outline 4-hydroxyphenylglyoxylate Identifier CHEBI:58586 (Beilstein: 3543590) ^help_outline Charge -1 Formula C8H5O4 InChIKey^help_outline KXFJZKUFXHWWAJ-UHFFFAOYSA-M SMILES^help_outline Oc1ccc(cc1)C(=O)C([O-])=O 2D coordinates Mol file for the small molecule Search links Involved in 2 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
Name ^help_outline L-glutamate Identifier CHEBI:29985 (CAS: 11070-68-1) ^help_outline Charge -1 Formula C5H8NO4 InChIKey^help_outline WHUUTDBJXJRKMK-VKHMYHEASA-M SMILES^help_outline [NH3+][C@@H](CCC([O-])=O)C([O-])=O 2D coordinates Mol file for the small molecule Search links Involved in 249 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule

Cross-references

	RHEA:15589	RHEA:15590	RHEA:15591	RHEA:15592
Reaction direction	undefined	left-to-right	right-to-left	bidirectional
UniProtKB ^help_outline
EC numbers ^help_outline	2.6.1.72
Gene Ontology ^help_outline	GO:0047320
KEGG ^help_outline				R04234
MetaCyc ^help_outline				2.6.1.72-RXN

Comments

Published in: Van den Tweel, W.J.J., Ogg, R.L.H.P. and de Bont, J.A.M. Transamination with a D-transaminase from Pseudomonas putida and conversion of p-hydroxyphenylglyoxylate to D-p-hydroxyphenylglycine. Patent EP0315786, 1987, Neth. Appl. NL, 87 (1987), 02449. Van den Tweel, W.J.J., Smits, J.P., Ogg, R.L.H.P. and de Bont, J.A.M. The involvement of an enantioselective transaminase in the metabolism of D-3- and D-4-hydroxyphenylglycine in Pseudomonas putida. Appl. Microbiol. Biotechnol. 29 (1998) 224–230.

RHEA:15589 D-4-hydroxyphenylglycine + 2-oxoglutarate = 4-hydroxyphenylglyoxylate + L-glutamate

Enzymes

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Cross-references

Comments