Reaction participants Show >> << Hide
- Name help_outline A Identifier CHEBI:13193 Charge Formula R SMILEShelp_outline * 2D coordinates Mol file for the small molecule Search links Involved in 2,783 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
- Name help_outline H2O Identifier CHEBI:15377 (Beilstein: 3587155; CAS: 7732-18-5) help_outline Charge 0 Formula H2O InChIKeyhelp_outline XLYOFNOQVPJJNP-UHFFFAOYSA-N SMILEShelp_outline [H]O[H] 2D coordinates Mol file for the small molecule Search links Involved in 6,048 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
- Name help_outline uracil Identifier CHEBI:17568 (Beilstein: 606623; CAS: 66-22-8) help_outline Charge 0 Formula C4H4N2O2 InChIKeyhelp_outline ISAKRJDGNUQOIC-UHFFFAOYSA-N SMILEShelp_outline O=c1cc[nH]c(=O)[nH]1 2D coordinates Mol file for the small molecule Search links Involved in 20 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
- Name help_outline AH2 Identifier CHEBI:17499 Charge 0 Formula RH2 SMILEShelp_outline *([H])[H] 2D coordinates Mol file for the small molecule Search links Involved in 2,713 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
- Name help_outline barbiturate Identifier CHEBI:77938 Charge -1 Formula C4H3N2O3 InChIKeyhelp_outline GVLZYMDNTPNTLV-UHFFFAOYSA-N SMILEShelp_outline O=c1[cH-]c(=O)[nH]c(=O)[nH]1 2D coordinates Mol file for the small molecule Search links Involved in 2 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
- Name help_outline H+ Identifier CHEBI:15378 Charge 1 Formula H InChIKeyhelp_outline GPRLSGONYQIRFK-UHFFFAOYSA-N SMILEShelp_outline [H+] 2D coordinates Mol file for the small molecule Search links Involved in 9,176 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
Cross-references
RHEA:22752 | RHEA:22753 | RHEA:22754 | RHEA:22755 | |
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Publications
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Novel amidohydrolytic reactions in oxidative pyrimidine metabolism: analysis of the barbiturase reaction and discovery of a novel enzyme, ureidomalonase.
Soong C.-L., Ogawa J., Shimizu S.
Amidohydrolytic reactions in oxidative pyrimidine metabolism were investigated in detail. Barbiturase has been reported to catalyze the amidohydrolysis of barbituric acid to urea and malonic acid. However, purification of the enzyme revealed that it catalyzes the ring-opening of barbituric acid to ... >> More
Amidohydrolytic reactions in oxidative pyrimidine metabolism were investigated in detail. Barbiturase has been reported to catalyze the amidohydrolysis of barbituric acid to urea and malonic acid. However, purification of the enzyme revealed that it catalyzes the ring-opening of barbituric acid to ureidomalonic acid. The existence of a consecutive enzyme named ureidomalonase, which hydrolyzes ureidomalonic acid to urea and malonic acid, was also discovered during the purification of barbiturase. << Less
Biochem. Biophys. Res. Commun. 286:222-226(2001) [PubMed] [EuropePMC]
This publication is cited by 3 other entries.
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Metabolism of cytosine, thymine, uracil, and barbituric acid by bacterial enzymes.
HAYAISHI O., KORNBERG A.
J Biol Chem 197:717-732(1952) [PubMed] [EuropePMC]
This publication is cited by 1 other entry.
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On the decomposition of pyrimidines by bacteria. II. Studies with cell-free enzyme preparations.
LARA F.J.
J Bacteriol 64:279-285(1952) [PubMed] [EuropePMC]
This publication is cited by 1 other entry.
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Metabolism of pyrimidines by a soil bacterium.
WANG T.P., LAMPEN J.O.
J Biol Chem 194:775-783(1952) [PubMed] [EuropePMC]
This publication is cited by 1 other entry.
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Uracil oxidase and the isolation of barbituric acid from uracil oxidation.
WANG T.P., LAMPEN J.O.
J Biol Chem 194:785-791(1952) [PubMed] [EuropePMC]
This publication is cited by 1 other entry.