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- Name help_outline H+ Identifier CHEBI:15378 Charge 1 Formula H InChIKeyhelp_outline GPRLSGONYQIRFK-UHFFFAOYSA-N SMILEShelp_outline [H+] 2D coordinates Mol file for the small molecule Search links Involved in 9,176 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
- Name help_outline NADPH Identifier CHEBI:57783 (Beilstein: 10411862) help_outline Charge -4 Formula C21H26N7O17P3 InChIKeyhelp_outline ACFIXJIJDZMPPO-NNYOXOHSSA-J SMILEShelp_outline NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](COP([O-])(=O)OP([O-])(=O)OC[C@H]2O[C@H]([C@H](OP([O-])([O-])=O)[C@@H]2O)n2cnc3c(N)ncnc23)[C@@H](O)[C@H]1O 2D coordinates Mol file for the small molecule Search links Involved in 1,247 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
- Name help_outline selenodiglutathione Identifier CHEBI:71259 Charge -2 Formula C20H30N6O12S2Se InChIKeyhelp_outline GJEZZQVPWMCGSB-BJDJZHNGSA-L SMILEShelp_outline [NH3+][C@@H](CCC(=O)N[C@@H](CS[Se]SC[C@H](NC(=O)CC[C@H]([NH3+])C([O-])=O)C(=O)NCC([O-])=O)C(=O)NCC([O-])=O)C([O-])=O 2D coordinates Mol file for the small molecule Search links Involved in 2 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
- Name help_outline glutathione Identifier CHEBI:57925 Charge -1 Formula C10H16N3O6S InChIKeyhelp_outline RWSXRVCMGQZWBV-WDSKDSINSA-M SMILEShelp_outline [NH3+][C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(=O)[O-])C(=O)[O-] 2D coordinates Mol file for the small molecule Search links Involved in 100 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
- Name help_outline glutathioselenol Identifier CHEBI:71265 Charge -1 Formula C10H16N3O6SSe InChIKeyhelp_outline UUYVRXVWXDDDGX-WDSKDSINSA-M SMILEShelp_outline [NH3+][C@@H](CCC(=O)N[C@@H](CS[SeH])C(=O)NCC([O-])=O)C([O-])=O 2D coordinates Mol file for the small molecule Search links Involved in 2 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
- Name help_outline NADP+ Identifier CHEBI:58349 Charge -3 Formula C21H25N7O17P3 InChIKeyhelp_outline XJLXINKUBYWONI-NNYOXOHSSA-K SMILEShelp_outline NC(=O)c1ccc[n+](c1)[C@@H]1O[C@H](COP([O-])(=O)OP([O-])(=O)OC[C@H]2O[C@H]([C@H](OP([O-])([O-])=O)[C@@H]2O)n2cnc3c(N)ncnc23)[C@@H](O)[C@H]1O 2D coordinates Mol file for the small molecule Search links Involved in 1,253 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
Cross-references
| RHEA:34927 | RHEA:34928 | RHEA:34929 | RHEA:34930 | |
|---|---|---|---|---|
| Reaction direction help_outline | undefined | left-to-right | right-to-left | bidirectional |
| UniProtKB help_outline |
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| Gene Ontology help_outline | ||||
| MetaCyc help_outline | ||||
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Publications
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Selenium metabolism in Escherichia coli.
Turner R.J., Weiner J.H., Taylor D.E.
Escherichia coli will reduce selenite (SeO3(2-)) and selenate (SeO4(2-)) to elemental selenium Se0. Selenium will also become incorporated into proteins as part of the amino acids selenocysteine or selenomethionine. The reaction of selenite with glutathione produces selenodiglutathione (GS-Se-GS). ... >> More
Escherichia coli will reduce selenite (SeO3(2-)) and selenate (SeO4(2-)) to elemental selenium Se0. Selenium will also become incorporated into proteins as part of the amino acids selenocysteine or selenomethionine. The reaction of selenite with glutathione produces selenodiglutathione (GS-Se-GS). Selenodiglutathione and its subsequent reduction to glutathioselenol (GS-SeH) are likely the key intermediates in the possible metabolic fates of selenium. This review presents the possible pathways involving selenium in E. coli. Identification of intermediates and potential processes from uptake of the toxic oxyanions through to their detoxification will assist us in understanding the complexities of metalloid oxyanion metabolism in these bacteria. << Less
Biometals 11:223-227(1998) [PubMed] [EuropePMC]
This publication is cited by 4 other entries.