Reaction participants Show >> << Hide
- Name help_outline L-selenohomocysteine Identifier CHEBI:84850 Charge 0 Formula C4H9NO2Se InChIKeyhelp_outline RCWCGLALNCIQNM-VKHMYHEASA-N SMILEShelp_outline [NH3+][C@@H](CC[SeH])C([O-])=O 2D coordinates Mol file for the small molecule Search links Involved in 1 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
- Name help_outline 5-methyltetrahydropteroyltri-L-glutamate Identifier CHEBI:58207 Charge -4 Formula C30H35N9O12 InChIKeyhelp_outline HVRNKDVLFAVCJF-VJANTYMQSA-J SMILEShelp_outline CN1[C@@H](CNc2ccc(cc2)C(=O)N[C@@H](CCC(=O)N[C@@H](CCC(=O)N[C@@H](CCC([O-])=O)C([O-])=O)C([O-])=O)C([O-])=O)CNc2nc(N)[nH]c(=O)c12 2D coordinates Mol file for the small molecule Search links Involved in 2 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
- Name help_outline tetrahydropteroyltri-L-glutamate Identifier CHEBI:58140 Charge -4 Formula C29H33N9O12 InChIKeyhelp_outline RXWVHRYZTWZATH-XSLAGTTESA-J SMILEShelp_outline Nc1nc2NC[C@H](CNc3ccc(cc3)C(=O)N[C@@H](CCC(=O)N[C@@H](CCC(=O)N[C@@H](CCC([O-])=O)C([O-])=O)C([O-])=O)C([O-])=O)Nc2c(=O)[nH]1 2D coordinates Mol file for the small molecule Search links Involved in 2 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
- Name help_outline L-selenomethionine Identifier CHEBI:62621 Charge 0 Formula C5H11NO2Se InChIKeyhelp_outline RJFAYQIBOAGBLC-BYPYZUCNSA-N SMILEShelp_outline C[Se]CC[C@H]([NH3+])C([O-])=O 2D coordinates Mol file for the small molecule Search links Involved in 2 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
Cross-references
| RHEA:45016 | RHEA:45017 | RHEA:45018 | RHEA:45019 | |
|---|---|---|---|---|
| Reaction direction help_outline | undefined | left-to-right | right-to-left | bidirectional |
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Publications
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L-Selenohomocysteine: one-step synthesis from L-selenomethionine and kinetic analysis as substrate for methionine synthases.
Zhou Z.S., Smith A.E., Matthews R.G.
A single-step convenient synthesis of L-selenohomocysteine (SeHcy) from L-selenomethionine (SeMet) using sodium in liquid ammonia is described. Methionine synthases convert SeHcy to SeMet at rates comparable to their rates of conversion of L-homocysteine (Hcy) to L-methionine (Met). This study sug ... >> More
A single-step convenient synthesis of L-selenohomocysteine (SeHcy) from L-selenomethionine (SeMet) using sodium in liquid ammonia is described. Methionine synthases convert SeHcy to SeMet at rates comparable to their rates of conversion of L-homocysteine (Hcy) to L-methionine (Met). This study suggests that SeHcy generated from SeMet metabolism can be efficiently recycled to SeMet in mammals. << Less
Bioorg Med Chem Lett 10:2471-2475(2000) [PubMed] [EuropePMC]