Reaction participants Show >> << Hide
- Name help_outline prostaglandin E2 Identifier CHEBI:606564 (Beilstein: 8364130) help_outline Charge -1 Formula C20H31O5 InChIKeyhelp_outline XEYBRNLFEZDVAW-ARSRFYASSA-M SMILEShelp_outline CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC([O-])=O 2D coordinates Mol file for the small molecule Search links Involved in 15 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
- Name help_outline H2O Identifier CHEBI:15377 (Beilstein: 3587155; CAS: 7732-18-5) help_outline Charge 0 Formula H2O InChIKeyhelp_outline XLYOFNOQVPJJNP-UHFFFAOYSA-N SMILEShelp_outline [H]O[H] 2D coordinates Mol file for the small molecule Search links Involved in 6,048 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
- Name help_outline prostaglandin A2 Identifier CHEBI:133370 Charge -1 Formula C20H29O4 InChIKeyhelp_outline MYHXHCUNDDAEOZ-FOSBLDSVSA-M SMILEShelp_outline [C@H]1([C@H](C=CC1=O)/C=C/[C@H](CCCCC)O)C/C=C\CCCC(=O)[O-] 2D coordinates Mol file for the small molecule Search links Involved in 4 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
Cross-references
| RHEA:50536 | RHEA:50537 | RHEA:50538 | RHEA:50539 | |
|---|---|---|---|---|
| Reaction direction help_outline | undefined | left-to-right | right-to-left | bidirectional |
| UniProtKB help_outline |
|
|||
| Reactome help_outline |
Publications
-
Metabolism of prostaglandins E, A, and C in serum.
Polet H., Levine L.
Three prostaglandin-metabolizing enzymes were detected in human serum. One enzyme was a dehydrase that converted prostaglandin E to prostaglandin A, the second was a prostaglandin A isomerase that converted prostaglandin A to prostaglandin C and the third was a prostaglandin C isomerase that conve ... >> More
Three prostaglandin-metabolizing enzymes were detected in human serum. One enzyme was a dehydrase that converted prostaglandin E to prostaglandin A, the second was a prostaglandin A isomerase that converted prostaglandin A to prostaglandin C and the third was a prostaglandin C isomerase that converted prostaglandin C to prostaglandin B. All three were inactivated by sulfhydryl blocking agents. In human serum, only prostaglandin C isomerase had high activity, whereas the two other enzymes had very low activity. In rabbit serum both isomerases were very active, but dehydrase activity could not be detected. Prostaglandin C isomerase activity was also found in crystallized human serum albumin and rabbit serum albumin. << Less
J Biol Chem 250:351-357(1975) [PubMed] [EuropePMC]
This publication is cited by 5 other entries.