Reaction participants Show >> << Hide
- Name help_outline 3-dehydro-α,α-trehalose Identifier CHEBI:55511 (CAS: 24885-76-5) help_outline Charge 0 Formula C12H20O11 InChIKeyhelp_outline RWDAEQLSLJPBCR-RMHOUTLUSA-N SMILEShelp_outline OC[C@H]1O[C@H](O[C@H]2O[C@H](CO)[C@@H](O)C(=O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O 2D coordinates Mol file for the small molecule Search links Involved in 1 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
- Name help_outline H2O Identifier CHEBI:15377 (CAS: 7732-18-5) help_outline Charge 0 Formula H2O InChIKeyhelp_outline XLYOFNOQVPJJNP-UHFFFAOYSA-N SMILEShelp_outline [H]O[H] 2D coordinates Mol file for the small molecule Search links Involved in 6,485 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
- Name help_outline 3-dehydro-D-glucose Identifier CHEBI:55402 (Beilstein: 6697013) help_outline Charge 0 Formula C6H10O6 InChIKeyhelp_outline APIQNBNBIICCON-KCLVSGOISA-N SMILEShelp_outline OC[C@H]1OC(O)[C@H](O)C(=O)[C@@H]1O 2D coordinates Mol file for the small molecule Search links Involved in 4 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
- Name help_outline D-glucose Identifier CHEBI:4167 (CAS: 2280-44-6) help_outline Charge 0 Formula C6H12O6 InChIKeyhelp_outline WQZGKKKJIJFFOK-GASJEMHNSA-N SMILEShelp_outline OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O 2D coordinates Mol file for the small molecule Search links Involved in 163 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
Cross-references
| RHEA:78719 | RHEA:78720 | RHEA:78721 | RHEA:78722 | |
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| Reaction direction help_outline | undefined | left-to-right | right-to-left | bidirectional |
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Publications
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Alpha-3-ketoglucosidase of Agrobacterium tumefaciens.
Hayano K., Fukui S.
A 3-ketosucrose-degrading enzyme was purified 80-fold from the sonic extracts of Agrobacterium tumefaciens IAM 1525 grown on a sucrose-containing medium. The enzyme catalyzes hydrolysis of alpha-3-ketoglucosides such as 3-ketosucrose, 3-ketotrehalose, 3-ketomaltose, and 3-ketoglucose-1-phosphate b ... >> More
A 3-ketosucrose-degrading enzyme was purified 80-fold from the sonic extracts of Agrobacterium tumefaciens IAM 1525 grown on a sucrose-containing medium. The enzyme catalyzes hydrolysis of alpha-3-ketoglucosides such as 3-ketosucrose, 3-ketotrehalose, 3-ketomaltose, and 3-ketoglucose-1-phosphate but not of beta-3-ketoglucosides, beta-3-ketogalactosides, and other glycosides such as sucrose, trehalose, maltose, glucose-1-phosphate, cellobiose, lactose, or raffinose. From the strict substrate specificity of this enzyme, the name alpha-d-3-ketoglucoside 3-ketoglucohydrolase (trivial name, alpha-3-ketoglucosidase) was proposed. K(m) values for 3-ketosucrose and 3-ketotrehalose were 3.9 x 10(-3)m and 4.8 x 10(-3)m, respectively. Optimum pH was 8.0 to 8.3. 3-Ketoglucose, a reaction product from alpha-3-ketoglucosides by the enzyme, behaved as a strong inhibitor. Physiological significance of this enzyme in the disaccharide metabolism of this bacterium was discussed. << Less
J Bacteriol 101:692-697(1970) [PubMed] [EuropePMC]
This publication is cited by 2 other entries.
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Functional genetics of human gut commensal Bacteroides thetaiotaomicron reveals metabolic requirements for growth across environments.
Liu H., Shiver A.L., Price M.N., Carlson H.K., Trotter V.V., Chen Y., Escalante V., Ray J., Hern K.E., Petzold C.J., Turnbaugh P.J., Huang K.C., Arkin A.P., Deutschbauer A.M.
Harnessing the microbiota for beneficial outcomes is limited by our poor understanding of the constituent bacteria, as the functions of most of their genes are unknown. Here, we measure the growth of a barcoded transposon mutant library of the gut commensal Bacteroides thetaiotaomicron on 48 carbo ... >> More
Harnessing the microbiota for beneficial outcomes is limited by our poor understanding of the constituent bacteria, as the functions of most of their genes are unknown. Here, we measure the growth of a barcoded transposon mutant library of the gut commensal Bacteroides thetaiotaomicron on 48 carbon sources, in the presence of 56 stress-inducing compounds, and during mono-colonization of gnotobiotic mice. We identify 516 genes with a specific phenotype under only one or a few conditions, enabling informed predictions of gene function. For example, we identify a glycoside hydrolase important for growth on type I rhamnogalacturonan, a DUF4861 protein for glycosaminoglycan utilization, a 3-keto-glucoside hydrolase for disaccharide utilization, and a tripartite multidrug resistance system specifically for bile salt tolerance. Furthermore, we show that B. thetaiotaomicron uses alternative enzymes for synthesizing nitrogen-containing metabolic precursors based on ammonium availability and that these enzymes are used differentially in vivo in a diet-dependent manner. << Less
Cell Rep. 34:108789-108789(2021) [PubMed] [EuropePMC]
This publication is cited by 1 other entry.