Statistics for release 140 (2026-01-28)

The number of reactions given here is the number of reaction quartets.

Unique reactions: 18,343

Unique reaction participants: 15,125

Reaction participants help_outline
Type Participants Reactions
Small molecule (ChEBI) 12,884 18,275
Macromolecule (Rhea) 1,977 3,354
Polymer (Rhea) 264 328
Reactions by status help_outline
Approved 18,044
Preliminary 299
Reactions by qualifier
Chemically balanced 18,336
Transport 1,560
Linked database records
Database Data type Origin Unique database IDs Links Total reactions
EcoCyc Reaction Curated 1,617 1,662 1,650
MetaCyc Reaction Curated 9,402 9,720 9,563
Reactome Reaction Computed via ChEBI IDs 1,423 1,660 975
KEGG Reaction Curated 6,992 7,127 7,087
M-CSA Reaction Computed 138 138 136
Enzyme EC number Curated 6,184 7,902 7,613
PubMed Bibliographic citation Curated 18,680 38,000 17,366
ChEBI Compound Curated 14,185 86,404 18,343
GO Enzymes 4,431 4,431 4,429