Results (16,609 reactions)

Reaction identifier Equation Enzyme class Enzymes
RHEA:23376 L-threonate + NAD+ = 3-dehydro-D-erythronate + H+ + NADH
RHEA:23380 N-acetyl-α-D-glucosaminyl-diphosphodolichol + UDP-N-acetyl-α-D-glucosamine = H+ + N,N'-diacetylchitobiosyl diphosphodolichol + UDP
  • EC:2.4.1.141 N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase
3,267 protein(s) (UniProtKB)
RHEA:23384 D-cellobiose = β-D-glucosyl-(1→4)-D-mannopyranose 1,884 protein(s) (UniProtKB)
RHEA:23388 ATP + hygromycin B = 7''-O-phosphohygromycin B + ADP + H+ 1 protein(s) (UniProtKB)
RHEA:23392 (n-1) H2O + RNA(n) = n a ribonucleoside 5'-phosphate + n H+
RHEA:23396 H2O + phloretin = 1,3,5-trihydroxybenzene + H+ + phloretate 2 protein(s) (UniProtKB)
RHEA:23400 7,8-dihydroxykynurenate + O2 = 5-(3-carboxy-3-oxoprop-1-en-1-yl)-4,6-dihydroxypyridine-2-carboxylate + H+
RHEA:23404 (2E,6E,10E)-geranylgeranyl diphosphate + sn-glycerol 1-phosphate = diphosphate + sn-3-O-(geranylgeranyl)glycerol 1-phosphate
  • EC:2.5.1.41 phosphoglycerol geranylgeranyltransferase
5,092 protein(s) (UniProtKB)
RHEA:23408 NADP+ + precorrin-6B = 2 H+ + NADPH + precorrin-6A 5 protein(s) (UniProtKB)
RHEA:23412 H2O + N-acetylputrescine = acetate + putrescine 8 protein(s) (UniProtKB)
RHEA:23416 (2R)-O-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate + phosphate 8,383 protein(s) (UniProtKB)
RHEA:23420 α,α-trehalose 6-phosphate + H2O = α,α-trehalose + phosphate 15,792 protein(s) (UniProtKB)
RHEA:23424 α-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate 29,469 protein(s) (UniProtKB)
RHEA:23428 3-O-(β-D-GalNAc-(1→4)-β-D-GlcA-(1→3)-β-D-Gal-(1→3)-β-D-Gal-(1→4)-β-D-Xyl)-L-seryl-[protein] + UDP-α-D-glucuronate = 3-O-(β-D-GlcA-(1→3)-β-D-GalNAc-(1→4)-β-D-GlcA-(1→3)-β-D-Gal-(1→3)-β-D-Gal-(1→4)-β-D-Xyl)-L-seryl-[protein] + H+ + UDP
  • EC:2.4.1.226 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase
12 protein(s) (UniProtKB)
RHEA:23432 (4S)-limonene + O2 + reduced [NADPH—hemoprotein reductase] = (4S)-perillyl alcohol + H+ + H2O + oxidized [NADPH—hemoprotein reductase] 3 protein(s) (UniProtKB)
RHEA:23436 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + H2O = 2,5,6-triamino-4-hydroxypyrimidine + D-ribose 5-phosphate
6,661 protein(s) (UniProtKB)
RHEA:23440 4-chlorobenzoate + H2O = 4-hydroxybenzoate + chloride + H+
RHEA:23444 (S)-lactate + NAD+ = H+ + NADH + pyruvate 18,468 protein(s) (UniProtKB)
RHEA:23448 3-deoxy-α-D-manno-oct-2-ulosonate + CTP = CMP-3-deoxy-β-D-manno-octulosonate + diphosphate
  • EC:2.7.7.38 3-deoxy-manno-octulosonate cytidylyltransferase
18,445 protein(s) (UniProtKB)
RHEA:23452 2'-deoxyadenosine + ATP = ADP + dAMP + H+ 524 protein(s) (UniProtKB)
RHEA:23456 (9Z,12Z)-octadecadienoate + AH2 + O2 = A + crepenynate + 2 H2O
RHEA:23460 benzyl cetraxate + H2O = benzyl alcohol + cetraxate + H+
RHEA:23464 3-O-(β-D-GlcA-(1→3)-β-D-Gal-(1→3)-β-D-Gal-(1→4)-β-D-Xyl)-L-seryl-[protein] + UDP-N-acetyl-α-D-galactosamine = 3-O-(β-D-GalNAc-(1→4)-β-D-GlcA-(1→3)-β-D-Gal-(1→3)-β-D-Gal-(1→4)-β-D-Xyl)-L-seryl-[protein] + H+ + UDP
  • EC:2.4.1.174 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase
5 protein(s) (UniProtKB)
RHEA:23468 2-aminobenzenesulfonate + 2 H+ + NADH + O2 = 2,3-dihydroxybenzenesulfonate + NAD+ + NH4+ 2 protein(s) (UniProtKB)
RHEA:23472 2 α,α'-trehalose 6-mycolate = α,α'-trehalose 6,6'-bismycolate + α,α-trehalose 1,931 protein(s) (UniProtKB)
RHEA:23476 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate + H+ = (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O 41,807 protein(s) (UniProtKB)
RHEA:23480 2-methylene-3-methylsuccinate = dimethylmaleate 1 protein(s) (UniProtKB)
RHEA:23484 A + D-cellobiose = AH2 + D-cellobiono-1,5-lactone 1 protein(s) (UniProtKB)
RHEA:23488 1,4-benzoquinone + H+ + NADPH = hydroquinone + NADP+ 1 protein(s) (UniProtKB)
RHEA:23492 UDP-α-D-glucosamine = UDP-α-D-galactosamine
RHEA:23496 5-hydroxypentanoate + acetyl-CoA = 5-hydroxy-pentanoyl-CoA + acetate
RHEA:23500 H2O + N6-propanoyl-L-lysyl-[protein] + NAD+ = 3''-O-propanoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide
7 protein(s) (UniProtKB)
RHEA:23504 adenosylcob(III)inamide + H2O = (R)-1-aminopropan-2-ol + adenosylcob(III)yrate 2 protein(s) (UniProtKB)
RHEA:23508 (7R)-7-(4-carboxybutanamido)cephalosporanate + H2O = (7R)-7-aminocephalosporanate + glutarate
  • EC:3.5.1.93 glutaryl-7-aminocephalosporanic-acid acylase
4 protein(s) (UniProtKB)
RHEA:23512 α,α-trehalose + phosphate = β-D-glucose 1-phosphate + D-glucose 2 protein(s) (UniProtKB)
RHEA:23516 (R)-glycerate + ATP = (2R)-3-phosphoglycerate + ADP + H+ 750 protein(s) (UniProtKB)
RHEA:23520 acetyl-CoA + propanoate = acetate + propanoyl-CoA 2 protein(s) (UniProtKB)
RHEA:23524 1-O-(trans-cinnamoyl)-β-D-glucose + an alcohol = an alkyl cinnamate + β-D-glucose
RHEA:23532 ATP + cholate + CoA = AMP + choloyl-CoA + diphosphate 6 protein(s) (UniProtKB)
RHEA:23536 α-D-glucose 1-phosphate = α-D-glucose 6-phosphate
  • EC:5.4.2.2 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent)
  • EC:5.4.2.5 phosphoglucomutase (glucose-cofactor)
14,174 protein(s) (UniProtKB)
RHEA:23540 ATP + L-glutamate + tRNAGlu = AMP + diphosphate + L-glutamyl-tRNAGlu 50,792 protein(s) (UniProtKB)
RHEA:23544 a flavonol 3-O-β-D-glucosyl-(1→2)-β-D-glucoside + UDP-α-D-glucose = a flavonol 3-O-β-D-glucosyl-(1→2)-β-D-glucosyl-(1→2)-β-D-glucoside + H+ + UDP
RHEA:23548 guanosine966 in 16S rRNA + S-adenosyl-L-methionine = H+ + N2-methylguanosine966 in 16S rRNA + S-adenosyl-L-homocysteine
  • EC:2.1.1.171 16S rRNA (guanine(966)-N(2))-methyltransferase
6,133 protein(s) (UniProtKB)
RHEA:23552 2-methylpropane-1,2-diol + NAD+ = 2-hydroxy-2-methylpropanal + H+ + NADH 1 protein(s) (UniProtKB)
RHEA:23556 D-alanine + L-glutamine = γ-L-glutamyl-D-alanine + NH4+
RHEA:23560 adenosylcob(III)inamide-GDP + α-ribazole 5'-phosphate = adenosylcob(III)alamin 5'-phosphate + GMP + H+
  • EC:2.7.8.26 adenosylcobinamide-GDP ribazoletransferase
21,479 protein(s) (UniProtKB)
RHEA:23564 2 columbamine + O2 = 2 berberine + 2 H2O
RHEA:23568 (2E)-decenoyl-[ACP] = (3Z)-decenoyl-[ACP]
  • EC:5.3.3.14 trans-2-decenoyl-[acyl-carrier-protein] isomerase
6,207 protein(s) (UniProtKB)
RHEA:23572 3-methylbutanoyl-CoA + 3 H+ + 3 malonyl-CoA = 3 CO2 + 4 CoA + phlorisovalerophenone 3 protein(s) (UniProtKB)
RHEA:23576 (R)-N-methylcoclaurine + (S)-N-methylcoclaurine + O2 + reduced [NADPH—hemoprotein reductase] = berbamunine + H+ + 2 H2O + oxidized [NADPH—hemoprotein reductase] 1 protein(s) (UniProtKB)
RHEA:23580 prostaglandin H2 = prostaglandin I2 800 protein(s) (UniProtKB)
RHEA:23584 7,8-dihydropteroate + ATP + L-glutamate = 7,8-dihydrofolate + ADP + H+ + phosphate 10,227 protein(s) (UniProtKB)
RHEA:23588 oxalate + succinyl-CoA = oxalyl-CoA + succinate
RHEA:23592 glycerol + NADP+ = D-glyceraldehyde + H+ + NADPH 245 protein(s) (UniProtKB)
RHEA:23596 H2O + 2 NAD+ + UDP-α-D-glucose = 3 H+ + 2 NADH + UDP-α-D-glucuronate 46,412 protein(s) (UniProtKB)
RHEA:23600 2-oxoglutarate + L-2-aminohexanoate = 2-oxohexanoate + L-glutamate
RHEA:23604 kievitone hydrate = H2O + kievitone 1 protein(s) (UniProtKB)
RHEA:23608 H+ + H2O + N-isopropylammelide = cyanurate + isopropylamine
  • EC:3.5.4.42 N-isopropylammelide isopropylaminohydrolase
1 protein(s) (UniProtKB)
RHEA:23612 1,2-dihydro-α-santonin + NAD+ = α-santonin + H+ + NADH
RHEA:23616 1,2-dihydro-α-santonin + NADP+ = α-santonin + H+ + NADPH
RHEA:23620 ATP + N2-(2-carboxyethyl)-L-arginine = AMP + deoxyamidinoproclavaminate + diphosphate + H+
  • EC:6.3.3.4 (carboxyethyl)arginine beta-lactam-synthase
1 protein(s) (UniProtKB)
RHEA:23624 a 5,6-dihydrouridine in tRNA + NADP+ = a uridine in tRNA + H+ + NADPH
35,672 protein(s) (UniProtKB)
RHEA:23628 a β-D-galactosyl-(1→3)-N-acetyl-β-D-glucosaminyl derivative + GDP-β-L-fucose = a β-D-galactosyl-(1→3)-[α-L-fucosyl-(1→4)]-N-acetyl-β-D-glucosaminyl derivative + GDP + H+
  • EC:2.4.1.65 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase
474 protein(s) (UniProtKB)
RHEA:23632 D-threo-isocitrate + NAD+ = 2-oxoglutarate + CO2 + NADH 4,028 protein(s) (UniProtKB)
RHEA:23640 1-aminocyclopropane-1-carboxylate + L-ascorbate + O2 = CO2 + ethene + 2 H2O + hydrogen cyanide + L-dehydroascorbate 1,089 protein(s) (UniProtKB)
RHEA:23644 lithocholate + O2 + reduced [NADPH—hemoprotein reductase] = H+ + H2O + hyodeoxycholate + oxidized [NADPH—hemoprotein reductase] 1 protein(s) (UniProtKB)
RHEA:23648 dTDP-6-deoxy-β-L-talose + NADP+ = dTDP-4-dehydro-β-L-rhamnose + H+ + NADPH 1 protein(s) (UniProtKB)
RHEA:23652 N-terminal L-glutaminyl-[peptide] = N-terminal 5-oxo-L-prolyl-[peptide] + NH4+ 2,698 protein(s) (UniProtKB)
RHEA:23656 2-(carboxymethyl)-5-oxo-2,5-dihydro-2-furoate = 3-carboxy-cis,cis-muconate + H+
  • EC:5.5.1.2 3-carboxy-cis,cis-muconate cycloisomerase
4 protein(s) (UniProtKB)
RHEA:23660 4-imidazolone-5-propanoate + H2O = N-formimidoyl-L-glutamate 18,882 protein(s) (UniProtKB)
RHEA:23664 A + a (2R)-2-hydroxycarboxylate = a 2-oxocarboxylate + AH2 1 protein(s) (UniProtKB)
RHEA:23668 apo-[methylmalonyl-CoA:pyruvate carboxytransferase] + ATP + biotin = AMP + diphosphate + H+ + holo-[methylmalonyl-CoA:pyruvate carboxytransferase]
  • EC:6.3.4.9 biotin--[methylmalonyl-CoA-carboxytransferase] ligase
4 protein(s) (UniProtKB)
RHEA:23672 a quinone + L-quinate = 3-dehydroquinate + a quinol
  • EC:1.1.5.8 quinate/shikimate dehydrogenase (quinone)
2 protein(s) (UniProtKB)
RHEA:23676 ATP + meso-2,6-diaminoheptanedioate + UDP-N-acetyl-α-D-muramoyl-L-alanyl-D-glutamate = ADP + H+ + phosphate + UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminoheptanedioate
  • EC:6.3.2.13 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase
31,291 protein(s) (UniProtKB)
RHEA:23680 a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + H+ + phosphate 59,404 protein(s) (UniProtKB)
RHEA:23684 (S)-cis-N-methylcanadine + O2 + reduced [NADPH—hemoprotein reductase] = allocryptopine + 2 H+ + H2O + oxidized [NADPH—hemoprotein reductase] 1 protein(s) (UniProtKB)
RHEA:23688 adenine + H+ + H2O = hypoxanthine + NH4+ 22,028 protein(s) (UniProtKB)
RHEA:23692 (R)-malate = H2O + maleate 4 protein(s) (UniProtKB)
RHEA:23696 myo-inositol + O2 = D-glucuronate + H+ + H2O 4,333 protein(s) (UniProtKB)
RHEA:23700 (6R)-5,10-methenyltetrahydrofolate + H2O = (6R)-10-formyltetrahydrofolate + H+
  • EC:3.5.4.9 methenyltetrahydrofolate cyclohydrolase
48,070 protein(s) (UniProtKB)
RHEA:23704 GTP + 4 H2O = 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + formate + 3 H+ + 2 phosphate 35,389 protein(s) (UniProtKB)
RHEA:23708 [GlcNAc-(1→4)-Mur2Ac(oyl-L-Ala-γ-D-Glu-L-Lys-D-Ala-D-Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate + β-D-GlcNAc-(1→4)-Mur2Ac(oyl-L-Ala-γ-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate = [GlcNAc-(1→4)-Mur2Ac(oyl-L-Ala-γ-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans-octa-cis-undecaprenyl diphosphate + di-trans,octa-cis-undecaprenyl diphosphate + H+ 170,170 protein(s) (UniProtKB)
RHEA:23712 NADP+ + pregnan-21-ol = H+ + NADPH + pregnan-21-al
RHEA:23716 (3Z)-dodecenoyl-CoA = (2E)-dodecenoyl-CoA
  • EC:5.3.3.8 Delta(3)-Delta(2)-enoyl-CoA isomerase
3 protein(s) (UniProtKB)
RHEA:23720 ATP + hydrogencarbonate + propanoyl-CoA = (S)-methylmalonyl-CoA + ADP + H+ + phosphate 8,981 protein(s) (UniProtKB)
RHEA:23724 H2O + O2 + pyridoxal = 4-pyridoxate + H+ + H2O2
RHEA:23728 (5Z,8Z,11Z,14Z)-eicosatetraenoate + AH2 + 2 O2 = A + H2O + prostaglandin H2 559 protein(s) (UniProtKB)
RHEA:23732 (R)-5-diphosphomevalonate + ATP = ADP + CO2 + isopentenyl diphosphate + phosphate 3,347 protein(s) (UniProtKB)
RHEA:23736 5-hydroxyisourate + H2O = 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + H+ 16,066 protein(s) (UniProtKB)
RHEA:23744 2-oxoglutarate + L-histidinol phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate 44,815 protein(s) (UniProtKB)
RHEA:23748 ATP + GTP = diphosphate + pppGp(2'-5')A
RHEA:23752 all-trans-undecaprenol + ATP = ADP + all-trans-undecaprenyl phosphate + H+
RHEA:23756 D-arabinono-1,4-lactone + O2 = dehydro-D-arabinono-1,4-lactone + H+ + H2O2 1,165 protein(s) (UniProtKB)
RHEA:23760 H+ + H2 + oxidized coenzyme F420-(γ-L-Glu)(n) = reduced coenzyme F420-(γ-L-Glu)(n) 12 protein(s) (UniProtKB)
RHEA:23764 diphosphate + L-serine = H+ + O-phospho-L-serine + phosphate
RHEA:23768 a fatty acyl-CoA + sphing-4-enine = an N-acylsphing-4-enine + CoA + H+ 17 protein(s) (UniProtKB)
RHEA:23772 (2R,3S)-2,3-dihydroxy-2,3-dihydro-p-cumate + NAD+ = 2,3-dihydroxy-p-cumate + H+ + NADH
  • EC:1.3.1.58 2,3-dihydroxy-2,3-dihydro-p-cumate dehydrogenase
2 protein(s) (UniProtKB)
RHEA:23776 ATP + L-aspartate = 4-phospho-L-aspartate + ADP 59,909 protein(s) (UniProtKB)
RHEA:23780 H2O + oxaloacetate + propanoyl-CoA = (2S,3S)-2-methylcitrate + CoA + H+ 900 protein(s) (UniProtKB)
RHEA:23784 a quinone + L-proline = (S)-1-pyrroline-5-carboxylate + a quinol + H+ 26,191 protein(s) (UniProtKB)