Advanced search Browse

Results (17,783 reactions)

Reaction identifier Equation Enzyme class Enzymes
RHEA:21252 (S)-2-hydroxyglutarate + A = 2-oxoglutarate + AH2 4,258 protein(s) (UniProtKB)
RHEA:21256 3-phosphoshikimate + phosphoenolpyruvate = 5-O-(1-carboxyvinyl)-3-phosphoshikimate + phosphate
  • EC:2.5.1.19 3-phosphoshikimate 1-carboxyvinyltransferase
44,340 protein(s) (UniProtKB)
RHEA:21260 [thioredoxin]-disulfide + L-methionine + H2O = L-methionine (R)-S-oxide + [thioredoxin]-dithiol 3,112 protein(s) (UniProtKB)
RHEA:21264 glycolate + A = glyoxylate + AH2 14,321 protein(s) (UniProtKB)
RHEA:21268 (R)-canadine + 2 NADP+ = berberine + 2 NADPH + H+
RHEA:21272 spermidine + glutathione + ATP = glutathionylspermidine + ADP + phosphate + H+ 923 protein(s) (UniProtKB)
RHEA:21276 D-arabinitol + NADP+ = D-xylulose + NADPH + H+ 1 protein(s) (UniProtKB)
RHEA:21280 thiamine + 2 O2 + H2O = thiamine acetate + 2 H2O2 + H+
RHEA:21284 all-trans-retinol + NAD+ = all-trans-retinal + NADH + H+ 193 protein(s) (UniProtKB)
RHEA:21288 sn-glycerol 3-phosphate + D-glucose = D-glucose 6-phosphate + glycerol
  • EC:2.7.1.142 glycerol-3-phosphate--glucose phosphotransferase
RHEA:21292 a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H+
  • EC:2.7.1.153 phosphatidylinositol-4,5-bisphosphate 3-kinase
5,665 protein(s) (UniProtKB)
RHEA:21296 D-galactose + NAD+ = D-galactono-1,4-lactone + NADH + H+ 347 protein(s) (UniProtKB)
RHEA:21300 an N-acyl-1-β-D-(3-O-sulfo)-galactosyl-sphing-4-enine + H2O = a β-D-galactosyl-(1↔1ʼ)-N-acylsphing-4-enine + sulfate + H+ 473 protein(s) (UniProtKB)
RHEA:21304 ent-kaur-16-en-19-ol + reduced [NADPH—hemoprotein reductase] + O2 = ent-kaur-16-en-19-al + oxidized [NADPH—hemoprotein reductase] + 2 H2O + H+
RHEA:21308 (S)-2,3-epoxysqualene = cycloartenol 29 protein(s) (UniProtKB)
RHEA:21312 2,5-dihydroxybenzoate + H+ = hydroquinone + CO2
RHEA:21316 phorbol 12,13-dibutanoate + H2O = phorbol 13-butanoate + butanoate + H+
RHEA:21320 D-sorbitol + A = keto-L-sorbose + AH2
RHEA:21324 reduced [rubredoxin] + superoxide + 2 H+ = oxidized [rubredoxin] + H2O2 3,173 protein(s) (UniProtKB)
RHEA:21332 D-glucosamine + acetyl-CoA = N-acetyl-D-glucosamine + CoA + H+
RHEA:21336 pyridoxal + NAD+ = 4-pyridoxolactone + NADH + H+ 2 protein(s) (UniProtKB)
RHEA:21340 1,2-bis(4-hydroxy-3-methoxyphenyl)ethylene + O2 = 2 vanillin 2 protein(s) (UniProtKB)
RHEA:21348 10 malonyl-CoA + 8 H+ = tetracenomycin F2 + 10 CO2 + 10 CoA + 2 H2O 5 protein(s) (UniProtKB)
RHEA:21352 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + O2 = (1E,2Z)-3-hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-dien-4-oate + H+
  • EC:1.13.11.25 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4,5-dioxygenase
482 protein(s) (UniProtKB)
RHEA:21356 L-arabinitol + NAD+ = L-ribulose + NADH + H+
RHEA:21360 β-nicotinamide D-ribonucleotide + ATP + H+ = diphosphate + NAD+
  • EC:2.7.7.1 nicotinamide-nucleotide adenylyltransferase
7,797 protein(s) (UniProtKB)
RHEA:21364 N-(6-aminohexanoyl)-6-aminohexanoate + H2O = 2 6-aminohexanoate 28 protein(s) (UniProtKB)
RHEA:21368 urate + O2 + H2O = 5-hydroxyisourate + H2O2 7,079 protein(s) (UniProtKB)
RHEA:21372 urethane + H2O + H+ = ethanol + NH4+ + CO2 1 protein(s) (UniProtKB)
RHEA:21376 3-(4-hydroxyphenyl)pyruvate + O2 = (S)-4-hydroxymandelate + CO2 4 protein(s) (UniProtKB)
RHEA:21380 3,7,11,15-tetramethylhexadecanoate + ATP + CoA = phytanoyl-CoA + AMP + diphosphate 7 protein(s) (UniProtKB)
RHEA:21384 L-phenylalanine = (E)-cinnamate + NH4+ 4,016 protein(s) (UniProtKB)
RHEA:21388 L-2-aminohexano-6-lactam + H2O = L-lysine
RHEA:21392 2-phenylacetaldehyde + NAD+ + H2O = 2-phenylacetate + NADH + 2 H+ 3 protein(s) (UniProtKB)
RHEA:21396 (S)-methylmalonyl-CoA + Na+(in) + H+(out) = propanoyl-CoA + Na+(out) + CO2
  • EC:7.2.4.3 (S)-methylmalonyl-CoA decarboxylase (sodium-transporting)
9 protein(s) (UniProtKB)
RHEA:21400 2-oxoglutarate + NADP+ + CoA = succinyl-CoA + CO2 + NADPH
RHEA:21404 chloride + O2 = chlorite 2 protein(s) (UniProtKB)
RHEA:21408 L-phenylalanine + NAD+ + H2O = 3-phenylpyruvate + NH4+ + NADH + H+ 8 protein(s) (UniProtKB)
RHEA:21412 sn-glycerol 1-phosphate + NAD+ = dihydroxyacetone phosphate + NADH + H+ 2,002 protein(s) (UniProtKB)
RHEA:21416 sn-glycerol 1-phosphate + NADP+ = dihydroxyacetone phosphate + NADPH + H+ 2,002 protein(s) (UniProtKB)
RHEA:21420 prostaglandin I2 + NADP+ = 15-dehydro-prostaglandin I2 + NADPH + H+
  • EC:1.1.1.231 15-hydroxyprostaglandin-I dehydrogenase (NADP(+))
RHEA:21424 3α,7α,12β-trihydroxy-5β-cholanate + NADP+ = 3α,7α-dihydroxy-12-oxo-5β-cholanate + NADPH + H+
RHEA:21428 (2R)-3-sulfolactate = sulfite + pyruvate + H+ 4 protein(s) (UniProtKB)
RHEA:21432 (S)-malate + NAD+ = oxaloacetate + NADH + H+ 49,173 protein(s) (UniProtKB)
RHEA:21436 [translation elongation factor 2] + ATP = [translation elongation factor 2]-phosphate + ADP + H+ 1,065 protein(s) (UniProtKB)
RHEA:21440 a long-chain fatty aldehyde + 2 NADPH + O2 + H+ = a long-chain alkane + formate + 2 NADP+ + H2O 3,030 protein(s) (UniProtKB)
RHEA:21444 3-(2-hydroxyphenyl)propanoate + NAD+ = trans-2-coumarate + NADH + H+
RHEA:21448 N2 + 8 reduced [2Fe-2S]-[ferredoxin] + 16 ATP + 16 H2O = H2 + 8 oxidized [2Fe-2S]-[ferredoxin] + 2 NH4+ + 16 ADP + 16 phosphate + 6 H+ 17,524 protein(s) (UniProtKB)
RHEA:21452 a [peptide]-C-terminal glycine + 2 L-ascorbate + O2 = a [peptide]-C-terminal (2S)-2-hydroxyglycine + 2 monodehydro-L-ascorbate radical + H2O 3,168 protein(s) (UniProtKB)
RHEA:21456 (S)-tetrahydrocolumbamine + reduced [NADPH—hemoprotein reductase] + O2 = (S)-canadine + oxidized [NADPH—hemoprotein reductase] + 2 H2O + H+ 4 protein(s) (UniProtKB)
RHEA:21460 benzoin = 2 benzaldehyde 1 protein(s) (UniProtKB)
RHEA:21464 thiocyanate + H2O + 2 H+ = carbonyl sulfide + NH4+ 3 protein(s) (UniProtKB)
RHEA:21468 tylactone + dTDP-α-D-mycaminose = 5-O-β-D-mycaminosyltylactone + dTDP + H+ 1 protein(s) (UniProtKB)
RHEA:21472 citrate + ATP + CoA = (3S)-citryl-CoA + ADP + phosphate
RHEA:21476 [(1→3)-β-D-glucosyl](n) + UDP-α-D-glucose = [(1→3)-β-D-glucosyl](n+1) + UDP + H+ 7,919 protein(s) (UniProtKB)
RHEA:21480 2-furoyl-CoA + A + H2O = 5-hydroxy-2-furoyl-CoA + AH2 + H+
RHEA:21488 dalnigrein β-D-apiofuranosyl-(1→6)-β-D-glucopyranoside + H2O = dalnigrein + β-D-apiofuranosyl-(1→6)-D-glucopyranose + H+
RHEA:21492 2,3-dihydroxybenzoate + H+ = catechol + CO2 5 protein(s) (UniProtKB)
RHEA:21496 dimethylallyl diphosphate + H2O = prenol + diphosphate
RHEA:21500 UDP-α-D-glucose = UDP-4-dehydro-6-deoxy-α-D-glucose + H2O 1,091 protein(s) (UniProtKB)
RHEA:21504 aldehydo-D-ribose 5-phosphate + acetoin = 1-deoxy-D-altro-heptulose 7-phosphate + acetaldehyde
  • EC:2.2.1.4 acetoin--ribose-5-phosphate transaldolase
RHEA:21508 all-trans-retinyl hexadecanoate + H2O = retinol + hexadecanoate + H+
RHEA:21512 3,6-anhydro-L-galactonate = 2-dehydro-3-deoxy-L-galactonate 2 protein(s) (UniProtKB)
RHEA:21516 isopiperitenone = piperitenone
RHEA:21520 2 Fe(III)-[cytochrome b1] + formate = 2 Fe(II)-[cytochrome b1] + CO2 + H+
RHEA:21524 3-methyl-2-oxobutanoate + acetyl-CoA + H2O = (2S)-2-isopropylmalate + CoA + H+ 36,978 protein(s) (UniProtKB)
RHEA:21528 [phosphate](n) + H2O = [phosphate](n-1) + phosphate + H+ 10,226 protein(s) (UniProtKB)
RHEA:21532 glutathionylspermidine + glutathione + ATP = trypanothione + ADP + phosphate + H+ 2 protein(s) (UniProtKB)
RHEA:21536 (3S)-3-hydroxy-3-methylglutaryl-CoA = 3-methyl-(2E)-glutaconyl-CoA + H2O 5 protein(s) (UniProtKB)
RHEA:21540 N-(5-phospho-β-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate 36,861 protein(s) (UniProtKB)
RHEA:21544 (2E,6E)-farnesyl diphosphate + ATP = (2E,6E)-farnesyl triphosphate + ADP
RHEA:21548 N6-acetyl-L-lysyl-[α-tubulin] + H2O = L-lysyl-[α-tubulin] + acetate
1,053 protein(s) (UniProtKB)
RHEA:21552 a β-D-Gal-(1→4)-β-D-Glc-(1↔1)-Cer(d18:1(4E)) + CMP-N-acetyl-β-neuraminate = N-acetyl-α-neuraminyl-(2→6)-β-D-galactosyl-(1→4)-β-D-glucosyl-(1↔1)-ceramide + CMP + H+
  • EC:2.4.3.1 beta-galactoside alpha-(2,6)-sialyltransferase
RHEA:21556 [calmodulin]-L-lysine + S-adenosyl-L-methionine = [calmodulin]-N6-methyl-L-lysine + S-adenosyl-L-homocysteine + H+ 529 protein(s) (UniProtKB)
RHEA:21560 3-hydroxy-2-methyl-3-phytyl-2,3-dihydro-1,4-naphthoquinone + oxidized dithiothreitol = 1,4-dithiothreitol + 2,3-epoxyphylloquinone
  • EC:1.17.4.5 vitamin-K-epoxide reductase (warfarin-insensitive)
RHEA:21564 an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA 14,909 protein(s) (UniProtKB)
RHEA:21568 β-D-Gal-(1→3)-β-D-GlcNAc-(1→3)-β-D-Gal-(1→4)-D-Glc + H2O = β-D-galactosyl-(1→3)-N-acetyl-D-glucosamine + lactose 2 protein(s) (UniProtKB)
RHEA:21572 3-hydroxy-2-methyl-1H-quinolin-4-one + O2 = N-acetylanthranilate + CO + H+ 1 protein(s) (UniProtKB)
RHEA:21576 carnitine + H+ = 2-methylcholine + CO2
RHEA:21580 (2S)-2-acetolactate + H+ = (R)-acetoin + CO2 5,514 protein(s) (UniProtKB)
RHEA:21584 propane-1,2-diol 1-phosphate + NAD+ = hydroxyacetone phosphate + NADH + H+
RHEA:21588 N-acetyl-L-glutamate 5-semialdehyde + phosphate + NADP+ = N-acetyl-L-glutamyl 5-phosphate + NADPH + H+
  • EC:1.2.1.38 N-acetyl-gamma-glutamyl-phosphate reductase
35,138 protein(s) (UniProtKB)
RHEA:21592 (2S)-2-[(R)-1-carboxyethylamino]pentanoate + NAD+ + H2O = L-2-aminopentanoate + pyruvate + NADH + H+ 1 protein(s) (UniProtKB)
RHEA:21596 L-serine + NADP+ = 2-aminomalonate semialdehyde + NADPH + H+
RHEA:21600 anthranilate + benzoyl-CoA = N-benzoylanthranilate + CoA 55 protein(s) (UniProtKB)
RHEA:21604 styrene oxide = 2-phenylacetaldehyde 1 protein(s) (UniProtKB)
RHEA:21608 isoliquiritigenin + S-adenosyl-L-methionine = 2'-O-methylisoliquiritigenin + S-adenosyl-L-homocysteine + H+ 2 protein(s) (UniProtKB)
RHEA:21612 D-gluconate = 2-dehydro-3-deoxy-D-gluconate + H2O 429 protein(s) (UniProtKB)
RHEA:21616 a β-D-galactosyl-(1→3)-N-acetyl-α-D-galactosaminyl derivative + CMP-N-acetyl-β-neuraminate = an N-acetyl-α-neuraminyl-(2→3)-β-D-galactosyl-(1→3)-N-acetyl-α-D-galactosaminyl derivative + CMP + H+
  • EC:2.4.3.4 beta-galactoside alpha-2,3-sialyltransferase
3,380 protein(s) (UniProtKB)
RHEA:21620 FMNH2 + NAD+ = FMN + NADH + 2 H+ 1,048 protein(s) (UniProtKB)
RHEA:21624 FMNH2 + NADP+ = FMN + NADPH + 2 H+ 156 protein(s) (UniProtKB)
RHEA:21628 17α-hydroxyprogesterone + NADPH + O2 = androst-4-ene-3,17-dione + acetate + NADP+ + H2O
RHEA:21632 2 catechol + O2 = 2 1,2-benzoquinone + 2 H2O 213 protein(s) (UniProtKB)
RHEA:21636 (E)-4-coumarate + UDP-α-D-glucose = 4-O-(β-D-glucosyl)-trans-4-coumarate + UDP + H+ 5 protein(s) (UniProtKB)
RHEA:21640 prephenate + NADP+ = 3-(4-hydroxyphenyl)pyruvate + CO2 + NADPH 1,170 protein(s) (UniProtKB)
RHEA:21644 glycerol + ATP = sn-glycerol 3-phosphate + ADP + H+ 33,476 protein(s) (UniProtKB)
RHEA:21648 prephenate + H+ = 3-phenylpyruvate + CO2 + H2O 38,980 protein(s) (UniProtKB)
RHEA:21652 2-chlorobenzoate + NADH + O2 + H+ = catechol + chloride + CO2 + NAD+
RHEA:21656 CDP-α-D-paratose = CDP-3,6-dideoxy-α-D-mannose 1 protein(s) (UniProtKB)
RHEA:21660 benzaldehyde + NADP+ + H2O = benzoate + NADPH + 2 H+ 5 protein(s) (UniProtKB)