Advanced search Browse

Results (17,614 reactions)

Reaction identifier Equation Enzyme class Enzymes
RHEA:22864 L-lysine = D-lysine 654 protein(s) (UniProtKB)
RHEA:22868 thioglycolate + 3-chloro-L-alanine = S-carboxymethyl-L-cysteine + chloride + H+ 1 protein(s) (UniProtKB)
RHEA:22872 L-prolyl-[collagen] + 2-oxoglutarate + O2 = trans-3-hydroxy-L-prolyl-[collagen] + succinate + CO2 687 protein(s) (UniProtKB)
RHEA:22876 (R)-mandelamide + H2O = (R)-mandelate + NH4+ 1 protein(s) (UniProtKB)
RHEA:22880 L-arogenate + 2-oxoglutarate = prephenate + L-glutamate 238 protein(s) (UniProtKB)
RHEA:22884 glyoxylate + L-methionine = 4-methylsulfanyl-2-oxobutanoate + glycine 4 protein(s) (UniProtKB)
RHEA:22888 (R)-methylmalonyl-CoA = succinyl-CoA 3,700 protein(s) (UniProtKB)
RHEA:22892 (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NAD+ = (6R)-5,10-methenyltetrahydrofolate + NADH
  • EC:1.5.1.15 methylenetetrahydrofolate dehydrogenase (NAD(+))
12 protein(s) (UniProtKB)
RHEA:22896 n malonyl-CoA + acetyl-CoA + 2n NADPH + 2n H+ = a long-chain fatty acyl-CoA + n CO2 + 2n NADP+ + n CoA + H2O
RHEA:22900 (R)-acetoin + NAD+ = diacetyl + NADH + H+ 1 protein(s) (UniProtKB)
RHEA:22904 ent-7α-hydroxykaur-16-en-19-oate + reduced [NADPH—hemoprotein reductase] + O2 = gibberellin A12 aldehyde + oxidized [NADPH—hemoprotein reductase] + 2 H2O + H+
RHEA:22908 3',5'-cyclic AMP + H2O + H+ = 3',5'-cyclic IMP + NH4+ 1 protein(s) (UniProtKB)
RHEA:22912 L-valine + pyruvate = 3-methyl-2-oxobutanoate + L-alanine 2 protein(s) (UniProtKB)
RHEA:22916 4'-hydroxyacetophenone + NADPH + O2 + H+ = 4-acetoxyphenol + NADP+ + H2O 1 protein(s) (UniProtKB)
RHEA:22920 scyllo-inosose + L-glutamine = 1-amino-1-deoxy-scyllo-inositol + 2-oxoglutaramate 1 protein(s) (UniProtKB)
RHEA:22924 dCMP + H2O + H+ = dUMP + NH4+ 11 protein(s) (UniProtKB)
RHEA:22928 4-acetamidobutanoyl-CoA + H2O = 4-aminobutanoyl-CoA + acetate
RHEA:22932 an N-acetyl-β-D-glucosaminyl derivative + UDP-α-D-galactose = a β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl derivative + UDP + H+
  • EC:2.4.1.38 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase
604 protein(s) (UniProtKB)
RHEA:22936 N-acetyl-D-glucosamine 6-phosphate + H2O = D-glucosamine 6-phosphate + acetate
  • EC:3.5.1.25 N-acetylglucosamine-6-phosphate deacetylase
3,489 protein(s) (UniProtKB)
RHEA:22940 L-arginine + ATP = Nω-phospho-L-arginine + ADP + H+ 363 protein(s) (UniProtKB)
RHEA:22944 3β-hydroxy-5β-pregnane-20-one + NADP+ = 5β-pregnan-3,20-dione + NADPH + H+ 6 protein(s) (UniProtKB)
RHEA:22948 D-tagatofuranose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate 3,170 protein(s) (UniProtKB)
RHEA:22952 octanedioyl-CoA + O2 = (2E)-octenedioyl-CoA + H2O2
RHEA:22956 a 1-(1,2-saturated alkyl)-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(II)-[cytochrome b5] + O2 + 2 H+ = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(III)-[cytochrome b5] + 2 H2O 4 protein(s) (UniProtKB)
RHEA:22960 formononetin + reduced [NADPH—hemoprotein reductase] + O2 = calycosin + oxidized [NADPH—hemoprotein reductase] + H2O + H+ 1 protein(s) (UniProtKB)
RHEA:22964 L-ornithine + H+ = putrescine + CO2 12,445 protein(s) (UniProtKB)
RHEA:22968 butanal + NAD+ + CoA = butanoyl-CoA + NADH + H+
RHEA:22972 butanal + NADP+ + CoA = butanoyl-CoA + NADPH + H+
RHEA:22976 (25R)-3α,7α,12α-trihydroxy-5β-cholestan-26-oate + ATP + CoA = (25R)-3α,7α,12α-trihydroxy-5β-cholestan-26-oyl-CoA + AMP + diphosphate 6 protein(s) (UniProtKB)
RHEA:22980 a di-trans,poly-cis-dolichyl diphosphooligosaccharide + L-asparaginyl-[protein] = N4-(oligosaccharide-(1→4)-N-acetyl-β-D-glucosaminyl-(1→4)-N-acetyl-β-D-glucosaminyl)-L-asparaginyl-[protein] + a di-trans,poly-cis-dolichyl diphosphate + H+
  • EC:2.4.99.18 dolichyl-diphosphooligosaccharide--protein glycotransferase
8,356 protein(s) (UniProtKB)
RHEA:22984 oxamate + carbamoyl phosphate = N-carbamoyl-2-oxoglycine + phosphate 4 protein(s) (UniProtKB)
RHEA:22988 3-oxopropanoate + NADP+ + CoA = acetyl-CoA + CO2 + NADPH
  • EC:1.2.1.18 malonate-semialdehyde dehydrogenase (acetylating)
RHEA:22992 3-oxopropanoate + NAD+ + CoA = acetyl-CoA + CO2 + NADH
  • EC:1.2.1.18 malonate-semialdehyde dehydrogenase (acetylating)
RHEA:22996 L-ascorbate + H2O2 = L-dehydroascorbate + 2 H2O 1,244 protein(s) (UniProtKB)
RHEA:23000 (R)-pantoate + NAD+ = (R)-4-dehydropantoate + NADH + H+
RHEA:23004 a neolactoside nLc4Cer(d18:1(4E)) + UDP-N-acetyl-α-D-glucosamine = a neolactoside IV3-β-GlcNAc-nLc4Cer(d18:1(4E)) + UDP + H+
890 protein(s) (UniProtKB)
RHEA:23008 α,α-trehalose 6-phosphate + H2O = D-glucose 6-phosphate + D-glucose 2 protein(s) (UniProtKB)
RHEA:23012 a fatty acid + S-adenosyl-L-methionine = a fatty acid methyl ester + S-adenosyl-L-homocysteine 1 protein(s) (UniProtKB)
RHEA:23016 (2R,3S,4S)-3,4-leucopelargonidin + NADP+ = (2R,3R)-dihydrokaempferol + NADPH + H+
RHEA:23024 [(1→4)-β-D-glucosyl](n) + phosphate = [(1→4)-β-D-glucosyl](n-1) + α-D-glucose 1-phosphate
RHEA:23028 N6-biotinyl-L-lysyl-[protein] + malonyl-[ACP] = N6-carboxybiotinyl-L-lysyl-[protein] + acetyl-[ACP]
  • EC:2.1.3.10 malonyl-S-ACP:biotin-protein carboxyltransferase
2 protein(s) (UniProtKB)
RHEA:23032 2-formamido-N1-(5-O-phospho-β-D-ribosyl)acetamidine + ATP = 5-amino-1-(5-phospho-β-D-ribosyl)imidazole + ADP + phosphate + H+
  • EC:6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
43,297 protein(s) (UniProtKB)
RHEA:23036 2 inosine + O2 = 2 5'-dehydroinosine + 2 H2O
RHEA:23040 2-oxobutanoate + acetyl-CoA + H2O = (R)-2-ethylmalate + CoA + H+
RHEA:23044 N,N-dihydroxy-L-tyrosine + H+ = (E)-4-hydroxyphenylacetaldehyde oxime + CO2 + H2O
1 protein(s) (UniProtKB)
RHEA:23048 (S)-3-hydroxybutanoate + 2-oxoglutarate = (R)-2-hydroxyglutarate + acetoacetate 4,551 protein(s) (UniProtKB)
RHEA:23052 L-seryl-[pyruvate dehydrogenase E1 α subunit] + ATP = O-phospho-L-seryl-[pyruvate dehydrogenase E1 α subunit] + ADP + H+
  • EC:2.7.11.2 [pyruvate dehydrogenase (acetyl-transferring)] kinase
5,368 protein(s) (UniProtKB)
RHEA:23056 urea = cyanamide + H2O 642 protein(s) (UniProtKB)
RHEA:23060 a (2R,3S)-2-alkyl-3-hydroxyalkanoate + ATP = a cis-3-alkyl-4-alkyloxetan-2-one + AMP + diphosphate 3 protein(s) (UniProtKB)
RHEA:23064 an alkanesulfonate + FMNH2 + O2 = an aldehyde + FMN + sulfite + H2O + 2 H+ 5,219 protein(s) (UniProtKB)
RHEA:23068 6 (S)-methylmalonyl-CoA + propanoyl-CoA + 6 NADPH + 12 H+ = 6-deoxyerythronolide B + 6 CO2 + 6 NADP+ + 7 CoA + H2O 3 protein(s) (UniProtKB)
RHEA:23076 4-chlorobenzoyl-CoA + chloride + NADP+ = 2,4-dichlorobenzoyl-CoA + NADPH
RHEA:23080 L-rhamnonate = 2-dehydro-3-deoxy-L-rhamnonate + H2O 1,257 protein(s) (UniProtKB)
RHEA:23084 3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA = 7-methyl-3-oxooct-6-enoyl-CoA + acetate 1 protein(s) (UniProtKB)
RHEA:23088 O-alkylglycerone + ATP = a 1-O-alkylglycerone 3-phosphate + ADP + H+
RHEA:23092 hydroxyatrazine + H2O + H+ = N-isopropylammelide + ethylamine
  • EC:3.5.4.43 hydroxydechloroatrazine ethylaminohydrolase
1 protein(s) (UniProtKB)
RHEA:23096 4-amino-5-hydroxymethyl-2-methylpyrimidine + ATP = 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + ADP + H+ 11,241 protein(s) (UniProtKB)
RHEA:23100 dAMP + ATP = dADP + ADP 1,096 protein(s) (UniProtKB)
RHEA:23104 D-arabinose 5-phosphate = D-ribulose 5-phosphate 7,379 protein(s) (UniProtKB)
RHEA:23108 D-arabinono-1,4-lactone + H2O = D-arabinonate + H+ 3 protein(s) (UniProtKB)
RHEA:23112 6-methylsalicylate + H+ = 3-methylphenol + CO2 2,460 protein(s) (UniProtKB)
RHEA:23116 4-hydroxybenzoate + ATP + CoA = 4-hydroxybenzoyl-CoA + AMP + diphosphate 4 protein(s) (UniProtKB)
RHEA:23120 a dipeptide(out) + ATP + H2O = a dipeptide(in) + ADP + phosphate + H+ 8,713 protein(s) (UniProtKB)
RHEA:23124 2 (2R)-3-phosphoglycerate + 2 H+ = D-ribulose 1,5-bisphosphate + CO2 + H2O 172,414 protein(s) (UniProtKB)
RHEA:23128 4-hydroxybutanoate + ATP + CoA = 4-hydroxybutanoyl-CoA + AMP + diphosphate
  • EC:6.2.1.40 4-hydroxybutyrate--CoA ligase (AMP-forming)
2 protein(s) (UniProtKB)
RHEA:23132 hydrogen sulfide + 6 oxidized [2Fe-2S]-[ferredoxin] + 3 H2O = sulfite + 6 reduced [2Fe-2S]-[ferredoxin] + 7 H+
  • EC:1.8.7.1 assimilatory sulfite reductase (ferredoxin)
9,427 protein(s) (UniProtKB)
RHEA:23136 a primary amine + S-adenosyl-L-methionine = a methylated primary amine + S-adenosyl-L-homocysteine + H+ 4 protein(s) (UniProtKB)
RHEA:23140 β-nicotinamide D-ribonucleotide + H2O = D-ribose 5-phosphate + nicotinamide + H+
RHEA:23144 N-acetyl-α-D-glucosamine + NAD+ + H2O = N-acetyl-D-glucosaminate + NADH + 2 H+
RHEA:23148 propanoate + ATP = propanoyl phosphate + ADP 1,638 protein(s) (UniProtKB)
RHEA:23152 a ubiquinone + NADH + H+ = a ubiquinol + NAD+
5,272 protein(s) (UniProtKB)
RHEA:23156 (E)-(indol-3-yl)acetaldehyde oxime = (indol-3-yl)acetonitrile + H2O 1 protein(s) (UniProtKB)
RHEA:23160 L-rhamnopyranose = L-rhamnulose 4,007 protein(s) (UniProtKB)
RHEA:23164 a 7-O-hydroxy-flavonol + UDP-α-D-glucose = a flavonol 7-O-β-D-glucoside + UDP + H+ 6 protein(s) (UniProtKB)
RHEA:23168 coformycin + NADP+ = 8-oxocoformycin + NADPH + H+
RHEA:23172 L-seryl-[3-hydroxy-3-methylglutaryl-coenzyme A reductase] + ATP = O-phospho-L-seryl-[3-hydroxy-3-methylglutaryl-coenzyme A reductase] + ADP + H+
  • EC:2.7.11.31 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase
1,875 protein(s) (UniProtKB)
RHEA:23176 acetate + ATP + CoA = acetyl-CoA + AMP + diphosphate 29,665 protein(s) (UniProtKB)
RHEA:23180 a secondary alcohol + O2 = a ketone + H2O2
RHEA:23184 (6aS,11aS)-3,6a,9-trihydroxypterocarpan + dimethylallyl diphosphate = (6aS,11aS)-4-dimethylallyl-3,6a,9-trihydroxypterocarpan + diphosphate
  • EC:2.5.1.36 trihydroxypterocarpan dimethylallyltransferase
1 protein(s) (UniProtKB)
RHEA:23188 propane-1,3-diol + NAD+ = 3-hydroxypropanal + NADH + H+ 2 protein(s) (UniProtKB)
RHEA:23192 Mur2Ac(oyl-L-Ala-γ-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + UDP-N-acetyl-α-D-glucosamine = β-D-GlcNAc-(1→4)-Mur2Ac(oyl-L-Ala-γ-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + UDP + H+
  • EC:2.4.1.227 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase
1,571 protein(s) (UniProtKB)
RHEA:23196 L-2-aminoadipate + L-valine + L-cysteine + 3 ATP + H2O = N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine + 3 AMP + 3 diphosphate + 3 H+
  • EC:6.3.2.26 N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase
6 protein(s) (UniProtKB)
RHEA:23200 N6-methyl-L-lysine + O2 + H2O = L-lysine + formaldehyde + H2O2
RHEA:23204 chlorogenate + D-glucarate = 2-O-caffeoylglucarate + L-quinate
  • EC:2.3.1.98 chlorogenate--glucarate O-hydroxycinnamoyltransferase
RHEA:23208 trans-glutaconate + acetyl-CoA = (2E)-glutaconyl-CoA + acetate 2 protein(s) (UniProtKB)
RHEA:23212 N-acetyl-β-alanine + H2O = β-alanine + acetate
RHEA:23216 benzoyl-CoA + NADPH + O2 + H+ = 3-hydroxybenzoyl-CoA + NADP+ + H2O
RHEA:23220 4-chlorobenzoate + ATP + CoA = 4-chlorobenzoyl-CoA + AMP + diphosphate 3 protein(s) (UniProtKB)
RHEA:23224 trans-zeatin + UDP-α-D-glucose = O-β-D-glucosyl-trans-zeatin + UDP + H+ 1 protein(s) (UniProtKB)
RHEA:23228 L-lysine + NADPH + O2 = N6-hydroxy-L-lysine + NADP+ + H2O 6,495 protein(s) (UniProtKB)
RHEA:23232 hydrazine + 4 Fe(III)-[cytochrome c] = N2 + 4 Fe(II)-[cytochrome c] + 4 H+ 1 protein(s) (UniProtKB)
RHEA:23236 [protein]-L-glutamate 5-O-methyl ester + H2O = L-glutamyl-[protein] + methanol + H+ 37,106 protein(s) (UniProtKB)
RHEA:23240 (6S)-5-formyl-5,6,7,8-tetrahydrofolate + L-glutamate = N-formyl-L-glutamate + (6S)-5,6,7,8-tetrahydrofolate + H+ 5 protein(s) (UniProtKB)
RHEA:23244 S-adenosyl 3-(methylsulfanyl)propylamine + propane-1,3-diamine = norspermidine + S-methyl-5'-thioadenosine + H+ 3 protein(s) (UniProtKB)
RHEA:23248 myo-inositol + S-adenosyl-L-methionine = 1D-4-O-methyl-myo-inositol + S-adenosyl-L-homocysteine + H+ 1 protein(s) (UniProtKB)
RHEA:23252 a 2'-deoxyribonucleoside 5'-diphosphate + [thioredoxin]-disulfide + H2O = a ribonucleoside 5'-diphosphate + [thioredoxin]-dithiol 82,653 protein(s) (UniProtKB)
RHEA:23256 adenosylcob(III)yrinate a,c-diamide + 4 L-glutamine + 4 ATP + 4 H2O = adenosylcob(III)yrate + 4 L-glutamate + 4 ADP + 4 phosphate + 4 H+
  • EC:6.3.5.10 adenosylcobyric acid synthase (glutamine-hydrolyzing)
RHEA:23260 (15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + NAD+ = 15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoate + NADH + H+ 2,055 protein(s) (UniProtKB)
RHEA:23264 (15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + NADP+ = 15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoate + NADPH + H+
RHEA:23268 guanidinoacetate + H2O = urea + glycine