Advanced search Browse

Results (17,422 reactions)

Reaction identifier Equation Enzyme class Enzymes
RHEA:23128 4-hydroxybutanoate + ATP + CoA = 4-hydroxybutanoyl-CoA + AMP + diphosphate
  • EC:6.2.1.40 4-hydroxybutyrate--CoA ligase (AMP-forming)
2 protein(s) (UniProtKB)
RHEA:23132 hydrogen sulfide + 6 oxidized [2Fe-2S]-[ferredoxin] + 3 H2O = sulfite + 6 reduced [2Fe-2S]-[ferredoxin] + 7 H+
  • EC:1.8.7.1 assimilatory sulfite reductase (ferredoxin)
9,392 protein(s) (UniProtKB)
RHEA:23136 a primary amine + S-adenosyl-L-methionine = a methylated primary amine + S-adenosyl-L-homocysteine + H+ 4 protein(s) (UniProtKB)
RHEA:23140 β-nicotinamide D-ribonucleotide + H2O = D-ribose 5-phosphate + nicotinamide + H+
RHEA:23144 N-acetyl-α-D-glucosamine + NAD+ + H2O = N-acetyl-D-glucosaminate + NADH + 2 H+
RHEA:23148 propanoate + ATP = propanoyl phosphate + ADP 1,626 protein(s) (UniProtKB)
RHEA:23152 a ubiquinone + NADH + H+ = a ubiquinol + NAD+
5,233 protein(s) (UniProtKB)
RHEA:23156 (E)-(indol-3-yl)acetaldehyde oxime = (indol-3-yl)acetonitrile + H2O 1 protein(s) (UniProtKB)
RHEA:23160 L-rhamnopyranose = L-rhamnulose 3,985 protein(s) (UniProtKB)
RHEA:23164 a 7-O-hydroxy-flavonol + UDP-α-D-glucose = a flavonol 7-O-β-D-glucoside + UDP + H+ 6 protein(s) (UniProtKB)
RHEA:23168 coformycin + NADP+ = 8-oxocoformycin + NADPH + H+
RHEA:23172 L-seryl-[3-hydroxy-3-methylglutaryl-coenzyme A reductase] + ATP = O-phospho-L-seryl-[3-hydroxy-3-methylglutaryl-coenzyme A reductase] + ADP + H+
  • EC:2.7.11.31 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase
1,857 protein(s) (UniProtKB)
RHEA:23176 acetate + ATP + CoA = acetyl-CoA + AMP + diphosphate 29,486 protein(s) (UniProtKB)
RHEA:23180 a secondary alcohol + O2 = a ketone + H2O2
RHEA:23184 (6aS,11aS)-3,6a,9-trihydroxypterocarpan + dimethylallyl diphosphate = (6aS,11aS)-4-dimethylallyl-3,6a,9-trihydroxypterocarpan + diphosphate
  • EC:2.5.1.36 trihydroxypterocarpan dimethylallyltransferase
1 protein(s) (UniProtKB)
RHEA:23188 propane-1,3-diol + NAD+ = 3-hydroxypropanal + NADH + H+ 2 protein(s) (UniProtKB)
RHEA:23192 Mur2Ac(oyl-L-Ala-γ-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + UDP-N-acetyl-α-D-glucosamine = β-D-GlcNAc-(1→4)-Mur2Ac(oyl-L-Ala-γ-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + UDP + H+
  • EC:2.4.1.227 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase
1,554 protein(s) (UniProtKB)
RHEA:23196 L-2-aminoadipate + L-valine + L-cysteine + 3 ATP + H2O = N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine + 3 AMP + 3 diphosphate + 3 H+
  • EC:6.3.2.26 N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase
6 protein(s) (UniProtKB)
RHEA:23200 N6-methyl-L-lysine + O2 + H2O = L-lysine + formaldehyde + H2O2
RHEA:23204 chlorogenate + D-glucarate = 2-O-caffeoylglucarate + L-quinate
  • EC:2.3.1.98 chlorogenate--glucarate O-hydroxycinnamoyltransferase
RHEA:23208 trans-glutaconate + acetyl-CoA = (2E)-glutaconyl-CoA + acetate 2 protein(s) (UniProtKB)
RHEA:23212 N-acetyl-β-alanine + H2O = β-alanine + acetate
RHEA:23216 benzoyl-CoA + NADPH + O2 + H+ = 3-hydroxybenzoyl-CoA + NADP+ + H2O
RHEA:23220 4-chlorobenzoate + ATP + CoA = 4-chlorobenzoyl-CoA + AMP + diphosphate 3 protein(s) (UniProtKB)
RHEA:23224 trans-zeatin + UDP-α-D-glucose = O-β-D-glucosyl-trans-zeatin + UDP + H+ 1 protein(s) (UniProtKB)
RHEA:23228 L-lysine + NADPH + O2 = N6-hydroxy-L-lysine + NADP+ + H2O 5,828 protein(s) (UniProtKB)
RHEA:23232 hydrazine + 4 Fe(III)-[cytochrome c] = N2 + 4 Fe(II)-[cytochrome c] + 4 H+ 1 protein(s) (UniProtKB)
RHEA:23236 [protein]-L-glutamate 5-O-methyl ester + H2O = L-glutamyl-[protein] + methanol + H+ 37,036 protein(s) (UniProtKB)
RHEA:23240 (6S)-5-formyl-5,6,7,8-tetrahydrofolate + L-glutamate = N-formyl-L-glutamate + (6S)-5,6,7,8-tetrahydrofolate + H+ 5 protein(s) (UniProtKB)
RHEA:23244 S-adenosyl 3-(methylsulfanyl)propylamine + propane-1,3-diamine = norspermidine + S-methyl-5'-thioadenosine + H+ 3 protein(s) (UniProtKB)
RHEA:23248 myo-inositol + S-adenosyl-L-methionine = 1D-4-O-methyl-myo-inositol + S-adenosyl-L-homocysteine + H+ 1 protein(s) (UniProtKB)
RHEA:23252 a 2'-deoxyribonucleoside 5'-diphosphate + [thioredoxin]-disulfide + H2O = a ribonucleoside 5'-diphosphate + [thioredoxin]-dithiol 80,816 protein(s) (UniProtKB)
RHEA:23256 adenosylcob(III)yrinate a,c-diamide + 4 L-glutamine + 4 ATP + 4 H2O = adenosylcob(III)yrate + 4 L-glutamate + 4 ADP + 4 phosphate + 4 H+
  • EC:6.3.5.10 adenosylcobyric acid synthase (glutamine-hydrolyzing)
RHEA:23260 (15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + NAD+ = 15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoate + NADH + H+ 2,057 protein(s) (UniProtKB)
RHEA:23264 (15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + NADP+ = 15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoate + NADPH + H+
RHEA:23268 guanidinoacetate + H2O = urea + glycine
RHEA:23272 an N6-alkylaminopurine + UDP-α-D-glucose = an N6-alkylamino-7-β-D-glucosylpurine + UDP + H+
RHEA:23276 2-dehydropantoate = 3-methyl-2-oxobutanoate + formaldehyde
RHEA:23280 cysteamine + acetyl-CoA = S-acetylcysteamine + CoA
RHEA:23284 isopentenyl diphosphate = dimethylallyl diphosphate
  • EC:5.3.3.2 isopentenyl-diphosphate Delta-isomerase
18,126 protein(s) (UniProtKB)
RHEA:23288 acetaldehyde + NAD+ + CoA = acetyl-CoA + NADH + H+ 6,828 protein(s) (UniProtKB)
RHEA:23292 L-lombricine + ATP = N-phospho-L-lombricine + ADP + H+ 2 protein(s) (UniProtKB)
RHEA:23296 aceneuramate = aldehydo-N-acetyl-D-mannosamine + pyruvate 11,100 protein(s) (UniProtKB)
RHEA:23300 isopentenyl diphosphate + (2E)-geranyl diphosphate = (2Z,6E)-farnesyl diphosphate + diphosphate 467 protein(s) (UniProtKB)
RHEA:23304 atropine + H2O = tropate + tropine + H+ 1 protein(s) (UniProtKB)
RHEA:23308 D-glucarate + (E)-sinapoyl-CoA = 2-O-[(E)-sinapoyl]-D-glucarate + CoA
RHEA:23312 2 sucrose = 1F-β-D-fructosylsucrose + D-glucose 1 protein(s) (UniProtKB)
RHEA:23316 2'-deoxyuridine + 2-oxoglutarate + O2 = 2-deoxy-D-ribono-1,4-lactone + uracil + succinate + CO2
RHEA:23320 D-tryptophan + malonyl-CoA = N2-malonyl-D-tryptophan + CoA + H+
RHEA:23324 2'-phospho-[ligated tRNA] + NAD+ = mature tRNA + ADP-α-D-ribose 1'',2''-cyclic phosphate + nicotinamide 4,138 protein(s) (UniProtKB)
RHEA:23328 a 9-cis-epoxycarotenoid + O2 = a 12'-apo-carotenal + 2-cis,4-trans-xanthoxin 1,019 protein(s) (UniProtKB)
RHEA:23332 (2R)-3-phosphoglycerate + GTP = (2R)-3-phospho-glyceroyl phosphate + GDP
RHEA:23336 2 iodide + H2O2 + 2 H+ = diiodine + 2 H2O 424 protein(s) (UniProtKB)
RHEA:23340 3-deoxy-α-D-manno-oct-2-ulosonate = D-arabinose + pyruvate
RHEA:23344 a purine D-ribonucleoside + H2O = a purine nucleobase + D-ribose 3 protein(s) (UniProtKB)
RHEA:23348 (R)-2-(carboxymethyl)-5-oxo-2,5-dihydro-2-furoate + H+ = (4,5-dihydro-5-oxofuran-2-yl)-acetate + CO2 2 protein(s) (UniProtKB)
RHEA:23352 4-aminobutanoate + 2-oxoglutarate = succinate semialdehyde + L-glutamate
  • EC:2.6.1.19 4-aminobutyrate--2-oxoglutarate transaminase
2,855 protein(s) (UniProtKB)
RHEA:23356 L-seryl-[rhodopsin] + ATP = O-phospho-L-seryl-[rhodopsin] + ADP + H+ 825 protein(s) (UniProtKB)
RHEA:23360 L-tyrosyl-[glycogenin] + UDP-α-D-glucose = α-D-glucosyl-L-tyrosyl-[glycogenin] + UDP + H+ 2,576 protein(s) (UniProtKB)
RHEA:23368 phenylglyoxylate + H+ = benzaldehyde + CO2 2 protein(s) (UniProtKB)
RHEA:23372 UDP-N-acetyl-α-D-muramate + L-alanine + ATP = UDP-N-acetyl-α-D-muramoyl-L-alanine + ADP + phosphate + H+
  • EC:6.3.2.8 UDP-N-acetylmuramate--L-alanine ligase
38,555 protein(s) (UniProtKB)
RHEA:23376 L-threonate + NAD+ = 3-dehydro-D-erythronate + NADH + H+
RHEA:23380 an N-acetyl-α-D-glucosaminyl-diphospho-di-trans,poly-cis-dolichol + UDP-N-acetyl-α-D-glucosamine = an N,N'-diacetylchitobiosyl-diphospho-di-trans,poly-cis-dolichol + UDP + H+
  • EC:2.4.1.141 N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase
1,636 protein(s) (UniProtKB)
RHEA:23384 D-cellobiose = β-D-glucosyl-(1→4)-D-mannopyranose 1,889 protein(s) (UniProtKB)
RHEA:23388 hygromycin B + ATP = 7''-O-phosphohygromycin B + ADP + H+ 1 protein(s) (UniProtKB)
RHEA:23392 RNA(n) + (n-1) H2O = n a ribonucleoside 5'-phosphate + n H+
RHEA:23396 phloretin + H2O = phloretate + 1,3,5-trihydroxybenzene + H+ 2 protein(s) (UniProtKB)
RHEA:23400 7,8-dihydroxykynurenate + O2 = 5-(3-carboxy-3-oxoprop-1-en-1-yl)-4,6-dihydroxypyridine-2-carboxylate + H+
RHEA:23404 sn-glycerol 1-phosphate + (2E,6E,10E)-geranylgeranyl diphosphate = sn-3-O-(geranylgeranyl)glycerol 1-phosphate + diphosphate
  • EC:2.5.1.41 phosphoglycerol geranylgeranyltransferase
5,127 protein(s) (UniProtKB)
RHEA:23408 precorrin-6B + NADP+ = precorrin-6A + NADPH + 2 H+ 5 protein(s) (UniProtKB)
RHEA:23412 N-acetylputrescine + H2O = putrescine + acetate 8 protein(s) (UniProtKB)
RHEA:23416 (2R)-O-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate + phosphate 8,617 protein(s) (UniProtKB)
RHEA:23420 α,α-trehalose 6-phosphate + H2O = α,α-trehalose + phosphate 17,010 protein(s) (UniProtKB)
RHEA:23424 α-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate 29,980 protein(s) (UniProtKB)
RHEA:23428 3-O-(β-D-GalNAc-(1→4)-β-D-GlcA-(1→3)-β-D-Gal-(1→3)-β-D-Gal-(1→4)-β-D-Xyl)-L-seryl-[protein] + UDP-α-D-glucuronate = 3-O-(β-D-GlcA-(1→3)-β-D-GalNAc-(1→4)-β-D-GlcA-(1→3)-β-D-Gal-(1→3)-β-D-Gal-(1→4)-β-D-Xyl)-L-seryl-[protein] + UDP + H+
  • EC:2.4.1.226 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase
12 protein(s) (UniProtKB)
RHEA:23432 (4S)-limonene + reduced [NADPH—hemoprotein reductase] + O2 = (4S)-perillyl alcohol + oxidized [NADPH—hemoprotein reductase] + H2O + H+ 3 protein(s) (UniProtKB)
RHEA:23436 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + H2O = 2,5,6-triamino-4-hydroxypyrimidine + D-ribose 5-phosphate
6,995 protein(s) (UniProtKB)
RHEA:23440 4-chlorobenzoate + H2O = 4-hydroxybenzoate + chloride + H+
RHEA:23444 (S)-lactate + NAD+ = pyruvate + NADH + H+ 17,321 protein(s) (UniProtKB)
RHEA:23448 3-deoxy-α-D-manno-oct-2-ulosonate + CTP = CMP-3-deoxy-β-D-manno-octulosonate + diphosphate
  • EC:2.7.7.38 3-deoxy-manno-octulosonate cytidylyltransferase
18,706 protein(s) (UniProtKB)
RHEA:23452 2'-deoxyadenosine + ATP = dAMP + ADP + H+ 547 protein(s) (UniProtKB)
RHEA:23456 (9Z,12Z)-octadecadienoate + AH2 + O2 = crepenynate + A + 2 H2O
RHEA:23460 benzyl cetraxate + H2O = cetraxate + benzyl alcohol + H+
RHEA:23464 3-O-(β-D-GlcA-(1→3)-β-D-Gal-(1→3)-β-D-Gal-(1→4)-β-D-Xyl)-L-seryl-[protein] + UDP-N-acetyl-α-D-galactosamine = 3-O-(β-D-GalNAc-(1→4)-β-D-GlcA-(1→3)-β-D-Gal-(1→3)-β-D-Gal-(1→4)-β-D-Xyl)-L-seryl-[protein] + UDP + H+
  • EC:2.4.1.174 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase
5 protein(s) (UniProtKB)
RHEA:23468 2-aminobenzenesulfonate + NADH + O2 + 2 H+ = 2,3-dihydroxybenzenesulfonate + NH4+ + NAD+ 2 protein(s) (UniProtKB)
RHEA:23472 2 α,α'-trehalose 6-mycolate = α,α'-trehalose 6,6'-bismycolate + α,α-trehalose 2,071 protein(s) (UniProtKB)
RHEA:23476 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate + H+ = (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O 42,764 protein(s) (UniProtKB)
RHEA:23480 2-methylene-3-methylsuccinate = dimethylmaleate 1 protein(s) (UniProtKB)
RHEA:23484 D-cellobiose + A = D-cellobiono-1,5-lactone + AH2 1 protein(s) (UniProtKB)
RHEA:23488 1,4-benzoquinone + NADPH + H+ = hydroquinone + NADP+ 1 protein(s) (UniProtKB)
RHEA:23492 UDP-α-D-glucosamine = UDP-α-D-galactosamine
RHEA:23496 5-hydroxypentanoate + acetyl-CoA = 5-hydroxy-pentanoyl-CoA + acetate
RHEA:23500 N6-propanoyl-L-lysyl-[protein] + NAD+ + H2O = 3''-O-propanoyl-ADP-D-ribose + nicotinamide + L-lysyl-[protein]
7 protein(s) (UniProtKB)
RHEA:23504 adenosylcob(III)inamide + H2O = (R)-1-aminopropan-2-ol + adenosylcob(III)yrate 2 protein(s) (UniProtKB)
RHEA:23508 (7R)-7-(4-carboxybutanamido)cephalosporanate + H2O = (7R)-7-aminocephalosporanate + glutarate
  • EC:3.5.1.93 glutaryl-7-aminocephalosporanic-acid acylase
4 protein(s) (UniProtKB)
RHEA:23512 α,α-trehalose + phosphate = β-D-glucose 1-phosphate + D-glucose 2 protein(s) (UniProtKB)
RHEA:23516 (R)-glycerate + ATP = (2R)-3-phosphoglycerate + ADP + H+ 779 protein(s) (UniProtKB)
RHEA:23520 propanoate + acetyl-CoA = propanoyl-CoA + acetate 2 protein(s) (UniProtKB)
RHEA:23524 1-O-(trans-cinnamoyl)-β-D-glucose + an alcohol = an alkyl cinnamate + β-D-glucose
RHEA:23532 cholate + ATP + CoA = choloyl-CoA + AMP + diphosphate 6 protein(s) (UniProtKB)